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Concepts in Biology : A Historical Perspective
| Concepts in Biology : A Historical Perspective |
| Autore | Gilbert Marc |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Newark : , : John Wiley & Sons, Incorporated, , 2023 |
| Descrizione fisica | 1 online resource (340 pages) |
| Altri autori (Persone) | PirkmajerSergej |
| ISBN |
1-394-23632-8
1-394-23630-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Title Page -- Copyright Page -- Contents -- Preface -- Chapter 1. Historical Overview of Endocrinology, Neurology and Immunology -- 1.1. The history of endocrinology -- 1.2. The history of neurology -- 1.3. The history of immunology -- Chapter 2. Regulatory Systems Integrating External and Internal Changes -- 2.1. Regulatory systems: endocrine, nervous and immune -- 2.1.1. Endocrine system -- 2.1.2. Nervous system -- 2.1.3. Immune system -- 2.2. Origin and diversity of signals and communication modes -- 2.2.1. Origin -- 2.2.2. Diversity -- 2.2.3. Communication modes -- 2.3. Integration of extracellular signals: plasma membrane receptors -- 2.3.1. Chemical signals and mechanisms of action: receptor types and signaling modulation -- 2.3.2. Integration of multiple signal inputs: ratio of stimulatory vs inhibitory signals -- 2.3.3. Physical signals -- 2.4. Nuclear receptors -- 2.4.1. Chemical nature of signals and functional characteristics of nuclear receptors -- 2.4.2. Molecular mechanisms underlying regulation of gene transcription -- Chapter 3. Intracellular Events in Response to Signals -- 3.1. Signaling pathways -- 3.1.1. General overview -- 3.1.2. Signal termination -- 3.1.3. Control of protein activities: allostery, covalent modifications and proteolytic cleavage -- 3.1.4. Impaired cellular responses to extracellular signals -- 3.1.5. Subcellular localization and sequestration -- 3.1.6. Crosstalk -- 3.2. Sensing of extracellular and intracellular cues -- 3.2.1. Sensing of extracellular cues -- 3.2.2. Sensing of intracellular cues -- 3.3. Functional diversity of proteins -- 3.3.1. Multifaceted "master regulators" -- 3.3.2. Molecular motor proteins -- 3.3.3. Interactional domains -- 3.3.4. Carrier proteins -- 3.3.5. Decoy molecules -- 3.3.6. Heat shock proteins as molecular chaperones -- 3.3.7. Hormone-like peptides: molecular mimicry.
3.3.8. Telomerase and integrity of linear chromosomes -- Chapter 4. Integrative Aspects: From Cellular to Whole-Body Level -- 4.1. Homeostasis equilibrium: dynamic steady state -- 4.1.1. Regulation of systemic glucose homeostasis -- 4.1.2. Tissue homeostasis -- 4.1.3. Muscle and bone mass homeostasis -- 4.1.4. Whole-body energy homeostasis -- 4.1.5. Metabolism and cellular energy homeostasis -- 4.1.6. The gut microbiome and glucose homeostasis -- 4.1.7. Synaptic homeostasis -- 4.1.8. Open issues: membrane lipid homeostasis and acid-base homeostasis -- 4.2. Homeostasis disruption -- 4.2.1. Endocrine disorders: excess or impaired hormone secretion -- 4.2.2. Muscle energy wasting -- 4.2.3. Energy -- 4.2.4. Cell number and activity -- 4.3. Crosstalk between organs, tissues and regulatory systems -- 4.3.1. Axis concept -- 4.3.2. Crosstalk between neuroendocrine axes -- 4.3.3. Crosstalks between organs and brain -- 4.3.4. Crosstalk between immune, endocrine and nervous systems -- 4.3.5. Immune system and cancer cell interactions -- 4.3.6. Adjustments of intermediary metabolism: brain, skeletal muscle, cancer cells -- Chapter 5. Epigenetics and Circadian Rhythms: Role of Environmental Factors -- 5.1. Epigenetics: general overview -- 5.1.1. Epigenetic modifications of DNA and regulation of biological processes -- 5.1.2. Genomic imprinting -- 5.1.3. Setting and maintenance of DNA methylation -- 5.1.4. Evidence for non-genomic inheritance: epigenetic mechanisms -- 5.1.5. Nutritional influences on developmental epigenetics -- 5.1.6. Gut microbiome and epigenetic changes -- 5.1.7. Metabolites and epigenetic changes -- 5.1.8. Social environment and endocrine disruptor: epigenetic changes -- 5.1.9. Importance of epigenetics in the etiology of cancer -- 5.1.10. In vitro reprogramming systems -- 5.2. Circadian rhythms. 5.2.1. Circadian rhythms and the concept of a circadian clock -- 5.2.2. Overview of the mammalian clock -- 5.2.3. Mechanisms by which circadian clocks govern biological processes -- 5.2.4. How is the SCN clock connected to tissue and cellular functions? -- 5.2.5. Avian circadian clock -- 5.3. Conclusion -- Concluding Remarks -- References -- Index -- EULA. |
| Record Nr. | UNINA-9910830149403321 |
Gilbert Marc
|
||
| Newark : , : John Wiley & Sons, Incorporated, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Concepts in Biology : A Historical Perspective
| Concepts in Biology : A Historical Perspective |
| Autore | Gilbert Marc |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Newark : , : John Wiley & Sons, Incorporated, , 2023 |
| Descrizione fisica | 1 online resource (340 pages) |
| Altri autori (Persone) | PirkmajerSergej |
| Soggetto topico |
Biology - History
Homeostasis |
| ISBN |
9781394236329
1394236328 9781394236305 1394236301 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Title Page -- Copyright Page -- Contents -- Preface -- Chapter 1. Historical Overview of Endocrinology, Neurology and Immunology -- 1.1. The history of endocrinology -- 1.2. The history of neurology -- 1.3. The history of immunology -- Chapter 2. Regulatory Systems Integrating External and Internal Changes -- 2.1. Regulatory systems: endocrine, nervous and immune -- 2.1.1. Endocrine system -- 2.1.2. Nervous system -- 2.1.3. Immune system -- 2.2. Origin and diversity of signals and communication modes -- 2.2.1. Origin -- 2.2.2. Diversity -- 2.2.3. Communication modes -- 2.3. Integration of extracellular signals: plasma membrane receptors -- 2.3.1. Chemical signals and mechanisms of action: receptor types and signaling modulation -- 2.3.2. Integration of multiple signal inputs: ratio of stimulatory vs inhibitory signals -- 2.3.3. Physical signals -- 2.4. Nuclear receptors -- 2.4.1. Chemical nature of signals and functional characteristics of nuclear receptors -- 2.4.2. Molecular mechanisms underlying regulation of gene transcription -- Chapter 3. Intracellular Events in Response to Signals -- 3.1. Signaling pathways -- 3.1.1. General overview -- 3.1.2. Signal termination -- 3.1.3. Control of protein activities: allostery, covalent modifications and proteolytic cleavage -- 3.1.4. Impaired cellular responses to extracellular signals -- 3.1.5. Subcellular localization and sequestration -- 3.1.6. Crosstalk -- 3.2. Sensing of extracellular and intracellular cues -- 3.2.1. Sensing of extracellular cues -- 3.2.2. Sensing of intracellular cues -- 3.3. Functional diversity of proteins -- 3.3.1. Multifaceted "master regulators" -- 3.3.2. Molecular motor proteins -- 3.3.3. Interactional domains -- 3.3.4. Carrier proteins -- 3.3.5. Decoy molecules -- 3.3.6. Heat shock proteins as molecular chaperones -- 3.3.7. Hormone-like peptides: molecular mimicry.
3.3.8. Telomerase and integrity of linear chromosomes -- Chapter 4. Integrative Aspects: From Cellular to Whole-Body Level -- 4.1. Homeostasis equilibrium: dynamic steady state -- 4.1.1. Regulation of systemic glucose homeostasis -- 4.1.2. Tissue homeostasis -- 4.1.3. Muscle and bone mass homeostasis -- 4.1.4. Whole-body energy homeostasis -- 4.1.5. Metabolism and cellular energy homeostasis -- 4.1.6. The gut microbiome and glucose homeostasis -- 4.1.7. Synaptic homeostasis -- 4.1.8. Open issues: membrane lipid homeostasis and acid-base homeostasis -- 4.2. Homeostasis disruption -- 4.2.1. Endocrine disorders: excess or impaired hormone secretion -- 4.2.2. Muscle energy wasting -- 4.2.3. Energy -- 4.2.4. Cell number and activity -- 4.3. Crosstalk between organs, tissues and regulatory systems -- 4.3.1. Axis concept -- 4.3.2. Crosstalk between neuroendocrine axes -- 4.3.3. Crosstalks between organs and brain -- 4.3.4. Crosstalk between immune, endocrine and nervous systems -- 4.3.5. Immune system and cancer cell interactions -- 4.3.6. Adjustments of intermediary metabolism: brain, skeletal muscle, cancer cells -- Chapter 5. Epigenetics and Circadian Rhythms: Role of Environmental Factors -- 5.1. Epigenetics: general overview -- 5.1.1. Epigenetic modifications of DNA and regulation of biological processes -- 5.1.2. Genomic imprinting -- 5.1.3. Setting and maintenance of DNA methylation -- 5.1.4. Evidence for non-genomic inheritance: epigenetic mechanisms -- 5.1.5. Nutritional influences on developmental epigenetics -- 5.1.6. Gut microbiome and epigenetic changes -- 5.1.7. Metabolites and epigenetic changes -- 5.1.8. Social environment and endocrine disruptor: epigenetic changes -- 5.1.9. Importance of epigenetics in the etiology of cancer -- 5.1.10. In vitro reprogramming systems -- 5.2. Circadian rhythms. 5.2.1. Circadian rhythms and the concept of a circadian clock -- 5.2.2. Overview of the mammalian clock -- 5.2.3. Mechanisms by which circadian clocks govern biological processes -- 5.2.4. How is the SCN clock connected to tissue and cellular functions? -- 5.2.5. Avian circadian clock -- 5.3. Conclusion -- Concluding Remarks -- References -- Index -- EULA. |
| Record Nr. | UNINA-9911019450403321 |
|
Gilbert Marc
|
||
| Newark : , : John Wiley & Sons, Incorporated, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||