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Reactive Oxygen Species : Network Pharmacology and Therapeutic Applications / / edited by Harald H. H. W. Schmidt, Pietro Ghezzi, Antonio Cuadrado
| Reactive Oxygen Species : Network Pharmacology and Therapeutic Applications / / edited by Harald H. H. W. Schmidt, Pietro Ghezzi, Antonio Cuadrado |
| Edizione | [1st ed. 2021.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 |
| Descrizione fisica | 1 online resource (421 pages) |
| Disciplina | 616.12 |
| Collana | Handbook of Experimental Pharmacology |
| Soggetto topico |
Pharmacology
Cardiology Neurosciences Clinical biochemistry Neuroscience Medical Biochemistry Oxigen actiu Ús terapèutic Farmacologia |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-68510-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I: ROS Revisited: Changing the Focus from Oxidative Stress and Redox Biology to Redox Medicine -- Demystifying oxidative stress -- Oxidants in Physiological Processes -- Network Medicine-Based Unbiased Disease Modules for Drug and Diagnostic Target Identification in ROSopathies -- Part II Targeting antioxidant responses -- Development of Telintra as an Inhibitor of Glutathione S-Transferase P -- Perspectives on the Clinical Development of NRF2-Targeting Drugs -- Part III: Inhibiting ROS formation and toxification -- NOX Inhibitors: From Bench to Naxibs to Bedside -- Nitric Oxide Synthase Inhibitors into the Clinic at Last -- Xanthine Oxidoreductase Inhibitors -- Monoamine Oxidase Inhibitors: From Classic to New Clinical Approaches -- Inhibition of Myeloperoxidase -- Part IV: Stimulating/substituting ROS -- Effects of Mammalian Thioredoxin Reductase Inhibitors -- Cardiovascular Therapeutic Potential of the Redox Siblings, Nitric Oxide (NO•) and Nitroxyl (HNO), in the Setting of Reactive Oxygen Species Dysregulation -- Tetrahydrobiopterin and Nitric Oxide Synthase Recouplers -- Part V: Repairing ROS damage -- Soluble Guanylate Cyclase Stimulators and Activators – Peter Sander -- Inhibitors of Advanced Glycation End Product (AGE) Formation and Accumulation. |
| Record Nr. | UNINA-9910484847003321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Translational Insights into Mechanisms and Therapy of Organ Dysfunction in Sepsis and Trauma
| Translational Insights into Mechanisms and Therapy of Organ Dysfunction in Sepsis and Trauma |
| Autore | Martin Lukas |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (337 p.) |
| Soggetto topico |
Medicine
Immunology |
| Soggetto non controllato |
sepsis
trauma multiple organ failure SIRS animal models translational studies clinical trials |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557211403321 |
Martin Lukas
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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