GC/MS in clinical chemistry [[electronic resource] /] / Petra Gerhards ... [et al.] ; translated by G. Leach |
Pubbl/distr/stampa | Weinheim ; ; New York, : Wiley-VCH, c1999 |
Descrizione fisica | 1 online resource (259 p.) |
Disciplina |
616.07/56
616.0756 |
Altri autori (Persone) | GerhardsPetra |
Soggetto topico |
Clinical chemistry
Gas chromatography Mass spectrometry |
Soggetto genere / forma | Electronic books. |
ISBN |
1-281-75842-6
9786611758424 3-527-61404-4 3-527-61405-2 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
GC/MS in Clinical Chemistry; Contents; Part I Fundamental Principles of Analysis by Gas Chromatography and Mass Spectrometry; 1. Physical Theory and Equipment Design; 1.1 Adsorption; 1.2 Partition; 1.3 Design of a Gas Chromatography System; 2. Injection and Headspace Technique; 2.1 Injection; 2.1.1 Splitless Injection; 2.1.2 Split Injection; 2.1.3 Temperature-Programmed Injection; 2.1.4 On-Column Injection; 2.2 Headspace Technique; 2.2.1 Static Headspace; 2.2.2 Dynamic Headspace; 3. Columns and Carrier Gas; 3.1 Packed Columns; 3.2 Capillary Columns; 3.3 Stationary Phases; 3.4 Film Thickness
3.5 Carrier Gas4. GC Detectors and Mass Spectrometry; 4.1 Selectivity; 4.2 The Flame Ionization Detector (FID); 4.3 The Electron Capture Detector (ECD); 4.4 Mass Spectrometry; 4.4.1 Design and Function of a Quadrupole Mass Spectrometer; 4.4.2 Detection; 4.4.3 Sample Introduction - the GC/MS Interface; 4.4.4 The Total Ion Current (TIC); 4.4.5 Selected Ion Monitoring (SIM); 4.4.6 Data Processing; 5. Quantification; 5.1 Methods Based on Internal Standards; 5.2 Standard Addition; 5.3 External Calibration; 5.4 Quantification in the Split Mode; 5.5 Limits of Detection; References for Part I Part II Drug Screening6. Epidemiology of the Abuse of Drugs and Medicaments; 6.1 Introduction; 6.2 Specific Data and Trends; 6.2.1 Opiates/Opioids; 6.2.1.1 Heroin; 6.2.1.2 Codeine; 6.2.1.3 Dehydrocodeine (DHC); 6.2.1.4 Methadone; 6.2.1.5 Tramadol; 6.2.1.6 Tilidine; 6.2.1.7 Other Centrally Active Analgesics; 6.2.2 Peripheral Analgesics; 6.2.3 Benzodiazepines; 6.2.3.1 Diazepam; 6.2.3.2 Flunitrazepam; 6.2.3.3 Bromazepam; 6.2.4 Barbiturates; 6.2.5 Other Sedatives and Addictive Substances; 6.2.5.1 Chlormethiazole; 6.2.5.2 Antihistamines; 6.2.6 Amphetamines and Related Substances 6.2.6.1 Substances of the Drug Scene6.2.6.2 Psychoanaleptics and Antihypotonics; 6.2.6.3 Appetite Suppressants; 6.2.7 Designer Drugs; 6.2.8 Cannabis; 6.2.9 Cocaine; 6.2.10 Other Hallucinogens; 6.2.10.1 Lysergic Acid Diethylamide (LSD); 6.2.10.2 Other Indole Derivatives; 6.2.10.3 Mescalin; 6.2.10.4 Nutmeg; 6.2.10.5 Pipendine Denvatives; 6.2.10.6 Fly Agaric; 6.2.10.7 Biperiden; 6.2.11 Substances Taken by Sniffing; 7. Methods of Sample Preparation for Drug Analysis; 7.1 History of Sample Preparation; 7.2 The Principle of Solid Phase Extraction; 7.2.1 Practical Aspects 7.2.1.1 Sample Preparation for the Matrix Urine7.2.1.2 Sample Preparation for the Matrix Whole Blood; 7.3 Liquid-Liquid Extraction (LLE); 7.4 Comparison of SPE with LLE; 7.5 Quantitative Determination of Derivatized Drugs; 7.5.1 Introduction; 7.5.2 Determination of the Detection Limits; 7.5.3 Sample Preparation and Analysis of Real Samples; 8. Drug Screening from Urine by GC/MS; 8.1 General Aspects of Drug Screening from Urine; 8.1.1 Differentiation between Drug Screening and Other Screening Procedures; 8.1.2 Sample Material; 8.1.3 Possibilities for Manipulation of Samples 8.1.4 Immunological Methods of Analysis |
Record Nr. | UNINA-9910144142803321 |
Weinheim ; ; New York, : Wiley-VCH, c1999 | ||
![]() | ||
Lo trovi qui: Univ. Federico II | ||
|
GC/MS in clinical chemistry [[electronic resource] /] / Petra Gerhards ... [et al.] ; translated by G. Leach |
Pubbl/distr/stampa | Weinheim ; ; New York, : Wiley-VCH, c1999 |
Descrizione fisica | 1 online resource (259 p.) |
Disciplina |
616.07/56
616.0756 |
Altri autori (Persone) | GerhardsPetra |
Soggetto topico |
Clinical chemistry
Gas chromatography Mass spectrometry |
ISBN |
1-281-75842-6
9786611758424 3-527-61404-4 3-527-61405-2 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
GC/MS in Clinical Chemistry; Contents; Part I Fundamental Principles of Analysis by Gas Chromatography and Mass Spectrometry; 1. Physical Theory and Equipment Design; 1.1 Adsorption; 1.2 Partition; 1.3 Design of a Gas Chromatography System; 2. Injection and Headspace Technique; 2.1 Injection; 2.1.1 Splitless Injection; 2.1.2 Split Injection; 2.1.3 Temperature-Programmed Injection; 2.1.4 On-Column Injection; 2.2 Headspace Technique; 2.2.1 Static Headspace; 2.2.2 Dynamic Headspace; 3. Columns and Carrier Gas; 3.1 Packed Columns; 3.2 Capillary Columns; 3.3 Stationary Phases; 3.4 Film Thickness
3.5 Carrier Gas4. GC Detectors and Mass Spectrometry; 4.1 Selectivity; 4.2 The Flame Ionization Detector (FID); 4.3 The Electron Capture Detector (ECD); 4.4 Mass Spectrometry; 4.4.1 Design and Function of a Quadrupole Mass Spectrometer; 4.4.2 Detection; 4.4.3 Sample Introduction - the GC/MS Interface; 4.4.4 The Total Ion Current (TIC); 4.4.5 Selected Ion Monitoring (SIM); 4.4.6 Data Processing; 5. Quantification; 5.1 Methods Based on Internal Standards; 5.2 Standard Addition; 5.3 External Calibration; 5.4 Quantification in the Split Mode; 5.5 Limits of Detection; References for Part I Part II Drug Screening6. Epidemiology of the Abuse of Drugs and Medicaments; 6.1 Introduction; 6.2 Specific Data and Trends; 6.2.1 Opiates/Opioids; 6.2.1.1 Heroin; 6.2.1.2 Codeine; 6.2.1.3 Dehydrocodeine (DHC); 6.2.1.4 Methadone; 6.2.1.5 Tramadol; 6.2.1.6 Tilidine; 6.2.1.7 Other Centrally Active Analgesics; 6.2.2 Peripheral Analgesics; 6.2.3 Benzodiazepines; 6.2.3.1 Diazepam; 6.2.3.2 Flunitrazepam; 6.2.3.3 Bromazepam; 6.2.4 Barbiturates; 6.2.5 Other Sedatives and Addictive Substances; 6.2.5.1 Chlormethiazole; 6.2.5.2 Antihistamines; 6.2.6 Amphetamines and Related Substances 6.2.6.1 Substances of the Drug Scene6.2.6.2 Psychoanaleptics and Antihypotonics; 6.2.6.3 Appetite Suppressants; 6.2.7 Designer Drugs; 6.2.8 Cannabis; 6.2.9 Cocaine; 6.2.10 Other Hallucinogens; 6.2.10.1 Lysergic Acid Diethylamide (LSD); 6.2.10.2 Other Indole Derivatives; 6.2.10.3 Mescalin; 6.2.10.4 Nutmeg; 6.2.10.5 Pipendine Denvatives; 6.2.10.6 Fly Agaric; 6.2.10.7 Biperiden; 6.2.11 Substances Taken by Sniffing; 7. Methods of Sample Preparation for Drug Analysis; 7.1 History of Sample Preparation; 7.2 The Principle of Solid Phase Extraction; 7.2.1 Practical Aspects 7.2.1.1 Sample Preparation for the Matrix Urine7.2.1.2 Sample Preparation for the Matrix Whole Blood; 7.3 Liquid-Liquid Extraction (LLE); 7.4 Comparison of SPE with LLE; 7.5 Quantitative Determination of Derivatized Drugs; 7.5.1 Introduction; 7.5.2 Determination of the Detection Limits; 7.5.3 Sample Preparation and Analysis of Real Samples; 8. Drug Screening from Urine by GC/MS; 8.1 General Aspects of Drug Screening from Urine; 8.1.1 Differentiation between Drug Screening and Other Screening Procedures; 8.1.2 Sample Material; 8.1.3 Possibilities for Manipulation of Samples 8.1.4 Immunological Methods of Analysis |
Record Nr. | UNINA-9910830074703321 |
Weinheim ; ; New York, : Wiley-VCH, c1999 | ||
![]() | ||
Lo trovi qui: Univ. Federico II | ||
|
GC/MS in clinical chemistry / / Petra Gerhards ... [et al.] ; translated by G. Leach |
Pubbl/distr/stampa | Weinheim ; ; New York, : Wiley-VCH, c1999 |
Descrizione fisica | 1 online resource (259 p.) |
Disciplina |
616.07/56
616.0756 |
Altri autori (Persone) | GerhardsPetra |
Soggetto topico |
Clinical chemistry
Gas chromatography Mass spectrometry |
ISBN |
1-281-75842-6
9786611758424 3-527-61404-4 3-527-61405-2 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
GC/MS in Clinical Chemistry; Contents; Part I Fundamental Principles of Analysis by Gas Chromatography and Mass Spectrometry; 1. Physical Theory and Equipment Design; 1.1 Adsorption; 1.2 Partition; 1.3 Design of a Gas Chromatography System; 2. Injection and Headspace Technique; 2.1 Injection; 2.1.1 Splitless Injection; 2.1.2 Split Injection; 2.1.3 Temperature-Programmed Injection; 2.1.4 On-Column Injection; 2.2 Headspace Technique; 2.2.1 Static Headspace; 2.2.2 Dynamic Headspace; 3. Columns and Carrier Gas; 3.1 Packed Columns; 3.2 Capillary Columns; 3.3 Stationary Phases; 3.4 Film Thickness
3.5 Carrier Gas4. GC Detectors and Mass Spectrometry; 4.1 Selectivity; 4.2 The Flame Ionization Detector (FID); 4.3 The Electron Capture Detector (ECD); 4.4 Mass Spectrometry; 4.4.1 Design and Function of a Quadrupole Mass Spectrometer; 4.4.2 Detection; 4.4.3 Sample Introduction - the GC/MS Interface; 4.4.4 The Total Ion Current (TIC); 4.4.5 Selected Ion Monitoring (SIM); 4.4.6 Data Processing; 5. Quantification; 5.1 Methods Based on Internal Standards; 5.2 Standard Addition; 5.3 External Calibration; 5.4 Quantification in the Split Mode; 5.5 Limits of Detection; References for Part I Part II Drug Screening6. Epidemiology of the Abuse of Drugs and Medicaments; 6.1 Introduction; 6.2 Specific Data and Trends; 6.2.1 Opiates/Opioids; 6.2.1.1 Heroin; 6.2.1.2 Codeine; 6.2.1.3 Dehydrocodeine (DHC); 6.2.1.4 Methadone; 6.2.1.5 Tramadol; 6.2.1.6 Tilidine; 6.2.1.7 Other Centrally Active Analgesics; 6.2.2 Peripheral Analgesics; 6.2.3 Benzodiazepines; 6.2.3.1 Diazepam; 6.2.3.2 Flunitrazepam; 6.2.3.3 Bromazepam; 6.2.4 Barbiturates; 6.2.5 Other Sedatives and Addictive Substances; 6.2.5.1 Chlormethiazole; 6.2.5.2 Antihistamines; 6.2.6 Amphetamines and Related Substances 6.2.6.1 Substances of the Drug Scene6.2.6.2 Psychoanaleptics and Antihypotonics; 6.2.6.3 Appetite Suppressants; 6.2.7 Designer Drugs; 6.2.8 Cannabis; 6.2.9 Cocaine; 6.2.10 Other Hallucinogens; 6.2.10.1 Lysergic Acid Diethylamide (LSD); 6.2.10.2 Other Indole Derivatives; 6.2.10.3 Mescalin; 6.2.10.4 Nutmeg; 6.2.10.5 Pipendine Denvatives; 6.2.10.6 Fly Agaric; 6.2.10.7 Biperiden; 6.2.11 Substances Taken by Sniffing; 7. Methods of Sample Preparation for Drug Analysis; 7.1 History of Sample Preparation; 7.2 The Principle of Solid Phase Extraction; 7.2.1 Practical Aspects 7.2.1.1 Sample Preparation for the Matrix Urine7.2.1.2 Sample Preparation for the Matrix Whole Blood; 7.3 Liquid-Liquid Extraction (LLE); 7.4 Comparison of SPE with LLE; 7.5 Quantitative Determination of Derivatized Drugs; 7.5.1 Introduction; 7.5.2 Determination of the Detection Limits; 7.5.3 Sample Preparation and Analysis of Real Samples; 8. Drug Screening from Urine by GC/MS; 8.1 General Aspects of Drug Screening from Urine; 8.1.1 Differentiation between Drug Screening and Other Screening Procedures; 8.1.2 Sample Material; 8.1.3 Possibilities for Manipulation of Samples 8.1.4 Immunological Methods of Analysis |
Record Nr. | UNINA-9910840548503321 |
Weinheim ; ; New York, : Wiley-VCH, c1999 | ||
![]() | ||
Lo trovi qui: Univ. Federico II | ||
|