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Biology of vascular smooth muscle : vasoconstriction and dilatation / / Yuansheng Gao
| Biology of vascular smooth muscle : vasoconstriction and dilatation / / Yuansheng Gao |
| Autore | Gao Yuansheng |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Singapore : , : Springer, , [2022] |
| Descrizione fisica | 1 online resource (422 pages) |
| Disciplina | 599.0116 |
| Soggetto topico |
Vascular smooth muscle
Vascular smooth muscle - Physiology Múscul llis Sistema cardiovascular Fisiologia humana |
| Soggetto genere / forma | Llibres electrònics |
| ISBN |
9789811971228
9789811971211 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface to the Second Edition -- Contents -- Part I: General Properties of Vasculature -- Chapter 1: Architecture of the Blood Vessels -- 1.1 Introduction -- 1.2 Architecture of the Arteries -- 1.3 Capillaries and Microcirculation -- 1.4 Architecture of the Veins -- 1.5 Gap Junctions -- 1.6 Vasa Vasorum -- 1.7 Adventitia and Perivascular Cells -- References -- Chapter 2: Ultrastructure of Vascular Smooth Muscle -- 2.1 Introduction -- 2.2 Thin Filaments -- 2.3 Thick Filaments -- 2.4 Organization of the Thin and Thick Filaments -- 2.5 Sarcoplasmic Reticulum -- 2.6 Mitochondria -- 2.7 Cytoskeleton -- References -- Chapter 3: Vascular Endothelium -- 3.1 Introduction -- 3.2 Permeability Activity: The Paracellular Route -- 3.3 Permeability Activity: The Transcellular Route -- 3.4 Leukocyte Transendothelial Migration -- 3.5 Modulation of Coagulation and Fibrinolysis -- 3.6 Vasculogenesis and Angiogenesis -- References -- Chapter 4: Electrical and Mechanical Properties of Vascular Smooth Muscle -- 4.1 Introduction -- 4.2 Electrical Properties of Vascular Smooth Muscle -- 4.3 Ionic Channels -- 4.4 Slow Waves and Vasomotion -- 4.5 Mechanical Properties of Vascular Smooth Muscle -- 4.6 Elastic and Collagenous Fibers -- References -- Chapter 5: Biochemistry of the Contractile Proteins of Smooth Muscle -- 5.1 Introduction -- 5.2 The Structural Basis of the Myosin Motor Activity -- 5.3 The Cross-Bridge Cycle -- 5.4 Heterogeneous Activities of Myosin Heavy Chain Isoforms -- 5.5 Myosin Light Chains -- 5.6 The Latch State -- References -- Chapter 6: Metabolism of Vascular Smooth Muscle -- 6.1 Introduction -- 6.2 Energy Metabolism -- 6.3 Glucose Metabolism -- 6.4 Lipid Metabolism -- 6.5 Amino Acid Metabolism -- References -- Part II: Regulators of Vasoreactivity -- Chapter 7: Neurotransmitters -- 7.1 Introduction -- 7.2 Innervation.
7.3 G Protein-Coupled Receptor -- 7.4 Adrenergic Signaling -- 7.5 Muscarinic Signaling -- 7.6 Purinergic Signaling -- 7.7 Signalings Via Neuropeptides -- References -- Chapter 8: Endothelium-Derived Factors -- 8.1 Introduction -- 8.2 Endothelium-Derived NO -- 8.3 Prostaglandin I2 -- 8.4 Endothelium-Dependent Hyperpolarization -- 8.5 ET-1 -- References -- Chapter 9: Local Metabolic Factors and Vasoactivity -- 9.1 Introduction -- 9.2 O2 Tension -- 9.3 CO2 and pH -- 9.4 Potassium -- 9.5 Adenosine -- 9.6 Lactate -- 9.7 Redundant Regulation of Exercise-Induced Vasodilatation -- References -- Chapter 10: Shear Stress, Myogenic Response, and Blood Flow Autoregulation -- 10.1 Introduction -- 10.2 Shear Stress -- 10.3 Myogenic Response -- 10.4 Blood Flow Autoregulation -- References -- Part III: Intracellular Signalings -- Chapter 11: Intracellular Ca2+ Regulation -- 11.1 Introduction -- 11.2 The Maintenance of Basal Cytosolic Ca2+ Levels -- 11.3 Ca2+ Entry Through Plasma Membrane Channels upon Membrane Depolarization -- 11.4 Stimulated Ca2+ Release from Sarcoplasmic Reticulum -- 11.5 Store-Operated Ca2+ Entry -- 11.6 Ca2+ Dynamics in VSMCs -- References -- Chapter 12: Regulation of Myosin Light Chain Phosphorylation -- 12.1 Introduction -- 12.2 Myosin Light Chain Phosphorylation -- 12.3 Myosin Light Chain Kinase -- 12.4 Myosin Light Chain Phosphatase -- 12.5 Protein Kinase C Signaling -- 12.6 Rho Kinase Signaling -- References -- Chapter 13: Cyclic AMP Signaling -- 13.1 Introduction -- 13.2 Adenylyl Cyclases -- 13.3 cAMP Hydrolyzing Phosphodiesterases -- 13.4 PKA -- 13.5 Epac -- 13.6 CNG Channels -- References -- Chapter 14: Cyclic GMP Signaling -- 14.1 Introduction -- 14.2 sGC -- 14.3 pGCs -- 14.4 cGMP Hydrolyzing PDEs -- 14.5 cGMP-Dependent Protein Kinase -- 14.6 CNG Channels -- References -- Chapter 15: MicroRNAs and Vascular Activity -- 15.1 Introduction. 15.2 miRNA Biogenesis -- 15.3 Mechanisms of miRNA-Mediated Gene Regulation -- 15.4 MiRNAs and Vascular Contractility -- 15.5 miRNAs as Biomarkers for Vascular Diseases -- 15.6 Therapeutic Potential of miRNAs in Vascular Diseases -- References -- Chapter 16: Extracellular Vesicles and Vascular Activity -- 16.1 Introduction -- 16.2 Biogenesis of Extracellular Vesicles -- 16.3 Extracellular Vesicles as Intercellular Messengers -- 16.4 Extracellular Vesicles and Vascular Homeostasis -- 16.5 Extracellular Vesicles and Vascular Diseases -- 16.6 Therapeutic Application of Extracellular Vesicles -- References -- Part IV: Heterogeneity in Vasoreactivity -- Chapter 17: Coronary Vasoreactivity -- 17.1 Introduction -- 17.2 Coronary Anatomy -- 17.3 Characteristics of Coronary Circulation -- 17.4 Myocardial Blood Flow and Myocardial Metabolism -- 17.5 Coronary Vasoreactivity and Hemodynamic Influence -- 17.6 Endothelium-Derived Vasoactive Factors and Coronary Vasoreactivity -- 17.7 Neuronal Influences on Coronary Vasoreactivity -- References -- Chapter 18: Cerebral Vasoreactivity -- 18.1 Introduction -- 18.2 The Anatomy of Cerebral Circulation -- 18.3 Cerebral Autoregulation -- 18.4 Neurovascular Coupling -- 18.5 Regulation of Cerebral Vasoreactivity -- 18.6 Autonomic Regulation of Cerebral Blood Flow -- References -- Chapter 19: Pulmonary Vasoreactivity -- 19.1 Introduction -- 19.2 The Anatomy of Pulmonary Vasculature -- 19.3 Characteristics of Pulmonary Circulation -- 19.4 Effects of Gravity and Alveolar Pressure on Pulmonary Perfusion -- 19.5 Effect of Lung Volume -- 19.6 Pulmonary Vascular Pressure and Flow -- 19.7 Endothelium and Pulmonary Vasoactivity -- 19.8 Autonomic Nervous Influence -- 19.9 Hypoxic Pulmonary Vasoconstriction (HPV) -- References -- Chapter 20: Hypoxic Vasoreactivity -- 20.1 Introduction -- 20.2 ROS and Hypoxic Vasoactivity. 20.3 Redox Modulation of Hypoxic Vasoactivity -- 20.4 AMPK and Hypoxic Vasoactivity -- 20.5 Erythrocyte-Dependent Hypoxic Vasoactivity -- 20.6 HIFs and Hypoxic Vasoactivity -- References -- Chapter 21: Ageing and Vasoreactivity -- 21.1 Introduction -- 21.2 Telomere and Vascular Ageing -- 21.3 Metabolism-Related Signalings and Vascular Ageing -- 21.4 Mitochondria and Vascular Ageing -- 21.5 Structural Characteristics of Ageing Blood Vessels -- 21.6 Functional Changes of Ageing Blood Vessels -- References. |
| Record Nr. | UNINA-9910634037703321 |
Gao Yuansheng
|
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| Singapore : , : Springer, , [2022] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biology of Vascular Smooth Muscle: Vasoconstriction and Dilatation [[electronic resource] /] / by Yuansheng Gao
| Biology of Vascular Smooth Muscle: Vasoconstriction and Dilatation [[electronic resource] /] / by Yuansheng Gao |
| Autore | Gao Yuansheng |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (XIII, 286 p. 43 illus., 33 illus. in color.) |
| Disciplina | 612 |
| Soggetto topico |
Human physiology
Cell physiology Angiology Molecular biology Human Physiology Cell Physiology Molecular Medicine |
| ISBN | 981-10-4810-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Architecture of the vessel wall -- Ultrastructure of vascular smooth muscle -- Vascular endothelium -- Electrical and mechanical properties of vascular smooth muscle -- Biochemistry of the contractile proteins of smooth muscle -- Metabolism of vascular smooth muscle -- Neurotransmitters -- Endothelium-derived factors -- Local metabolic factors -- Shear stress myogenic response and blood flow autoregulation -- Intracellular Ca2+ regulation -- Regulation of myosin light chain phosphorylation -- Cyclic AMP signalling -- Cyclic GMP signaling -- Coronary vasoreactivity -- Cerebral vasoreactivity -- Pulmonary vasoreactivity -- Hypoxic vasoreactivity -- Ageing and vasoreactivity. |
| Record Nr. | UNINA-9910253908703321 |
|
Gao Yuansheng
|
||
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||