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Challenges and Solutions Against Visceral Leishmaniasis [[electronic resource] /] / edited by Angamuthu Selvapandiyan, Ruchi Singh, Niti Puri, Nirmal K. Ganguly
| Challenges and Solutions Against Visceral Leishmaniasis [[electronic resource] /] / edited by Angamuthu Selvapandiyan, Ruchi Singh, Niti Puri, Nirmal K. Ganguly |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (XXI, 449 p. 36 illus., 34 illus. in color.) |
| Disciplina | 571.999 |
| Soggetto topico |
Parasitology
Drugs - Design Pharmaceutical chemistry Epidemiology Structure-Based Drug Design Pharmaceutics |
| ISBN | 981-9969-99-9 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Module 1_Epidemiology and Surveillances -- Module 2_Omics and Advancement in Diagnosis -- Module 3_Genetics -- Module 4_New Drug Discovery Opportunity -- Module 5_Immunity and Vaccine Development. |
| Record Nr. | UNINA-9910806194803321 |
| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Handbook of Oncobiology
| Handbook of Oncobiology |
| Autore | Sobti R. C |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Singapore : , : Springer, , 2024 |
| Descrizione fisica | 1 online resource (1584 pages) |
| Disciplina | 616.994 |
| Altri autori (Persone) |
GangulyNirmal K
KumarRakesh |
| ISBN | 981-9962-63-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Acknowledgments -- Contents -- About the Editors -- About the Section Editors -- Contributors -- Part I: Understanding, Milestones, and Advancements in Cancer Biology -- 1 An Introduction to Recent Approaches Underlying Mechanistic Insights Harboring Oncobiology -- Introduction -- Factors Harboring Oncogenesis -- Cancer Staging and Diagnosis -- Carcinogens and Carcinogenesis -- Genomics Genetic Instability and DNA Mutations -- Intriguing Avenues Within the Realm of Oncobiology -- Telomerase -- TGF-β -- E-cadherin -- Protein Kinase, Cell Cycle Alterations -- p53 -- miRNA in Cancer -- Epigenetic Alterations -- Modified Angiogenesis and Metastasis -- Warburg Metabolism -- Treatment Protocols -- Immune Evasion and Immunotherapy -- Potential Future Trajectories in Oncobiology -- New and Emerging Technologies -- Immunogenomics and Immunotherapy -- Personalized Medicine (Precision Oncology and Its Significance) -- Artificial Intelligence in Oncology -- Stem Cell Therapy and Development of Vaccines -- Epigenetic Alterations and Tumor Microenvironment -- Metabolomics -- Gut Microbiota -- Nanotechnology -- Conclusion -- References -- 2 Types of Cancers, Epidemiology, and Molecular Insights -- Introduction -- Differences Between Normal Cells and Cancer Cells -- Common and Rare Cancers -- Breast Cancer -- Lung Cancer -- Colorectal Cancer -- Prostate Cancer -- Skin Cancer -- Leukemia -- Lymphoma -- Ovarian Cancer -- Pancreatic Cancer -- Bladder Cancer -- Rare Cancers -- Esophageal Cancer -- Chronic Myeloid Leukemia (Also Called as Chronic Myelogenous Leukemia) (CML) -- Childhood Acute Lymphoblastic Leukemia -- Anal Cancer -- Merkel Cell Carcinoma -- Thymic Carcinoma -- Hepatoblastoma -- Glioblastoma -- Ewing Sarcoma -- Kaposi Sarcoma -- Characteristics of Cancer -- Ability for Self-Sufficiency in Growth Signals -- Evading Apoptosis.
Insensitivity to Anti-Growth Signals -- Sustained Angiogenesis -- Tissue Invasion and Metastasis -- Limitless Replication Potentials -- Reprogramming of Energy Metabolism -- Evasion of the Immune System -- Genome Instability -- Tumor-Promoting Inflammation -- Epidemiological and Etiological Advances in Understanding Cancers -- Oncogenes and Cancer Formation -- Etiological Factors in Cancer -- Understanding Cancer Etiology -- Age -- Child and Teen Cancer Incidence -- Infancy´s Impact -- Sexual Transmission -- Hormones -- Modifiable Risk Factors -- Sex -- Dietary Habits -- Socioeconomic Status -- Obesity -- Hygiene -- Microorganisms -- Tumorigenesis -- Cancer Genomics -- Epigenetics of Cancer -- Cancer Stem Cells -- Concluding Remarks -- References -- 3 Current Concepts and Advances in Oncobiology -- Introduction -- Viruses and Cancers -- Small DNA Tumor Viruses -- The Papillomavirus -- Merkel Cell Polyomavirus -- Polyomaviruses, SV40, and Adenoviruses -- Herpesviruses -- Hepatitis B Virus (HBV) -- RNA Oncoviruses -- Hepatitis C Virus (HCV) -- Retroviruses -- Human T-Lymphotropic Virus-1 (HTLV-1) -- Human Immunodeficiency Virus (HIV) -- Micro RNAs as Carcinogens -- Viral Molecule Diagnostic Efficacy in Cancer -- Hepatitis B Virus, Hepatitis C Virus: Hepatocellular Carcinoma -- Advances in Cancer -- Cancer Genetics -- Oncogenes -- Concluding Remarks -- References -- 4 Technological Advancements in Cancer Diagnosis and Prognosis -- Introduction -- Recent Advances in Cancer Diagnosis -- Fluid Biopsy -- Molecular Profiling -- Next-Generation Sequencing -- Role of MRI in Cancer Diagnosis -- Electrochemiluminescence (ECL) Nanosensing Systems -- Aptasensors -- M2 Pyruvate Kinase -- Staging and Grading of Cancers -- Classification of the TNM Staging System -- Staging Systems Other than the TNM System -- Ann Arbor´s Staging System -- FIGO Staging System. Importance of Cancer Staging (Cancer Staging Systems | ACS, n.d.) -- Classification of Cancer Grading -- Recent Developments in Prognosis -- MicroRNA as New Prognostic/Diagnostic Markers for Cancer -- Concluding Remarks -- References -- 5 Advanced Therapeutic Approaches in Cancer Therapy -- Introduction -- Precision Oncology -- Precision Surgery -- Recent Developments in Cancer Treatment -- Immunotherapy -- Immunomodulators -- Adoptive Cell Therapy -- CAR Constructs Can Be Divided into Five Generations -- Monoclonal Antibodies -- Dabrafenib-Trametinib -- Alfa-interferon Therapy -- Cancer Vaccines -- CRIPR/Cas9 -- DNA Cages -- HIPEC -- Hormone Therapy -- Nano Oncology -- Radiotherapy -- Oncolytic Virus Therapy -- Artificial Intelligence and Virtual Reality in Cancer Research -- Precision Oncology -- Precision Surgery -- Concluding Remarks -- References -- 6 History, Evolution, and Milestones in Cancer Research and Treatment -- Historical Aspects of Cancer Research and Treatment -- Oldest Descriptions of Cancer -- History of Cancer Research -- Cancer Chemotherapy -- Cancer Prevention with Vaccines -- Evolution of Cancer Research and Treatment -- Milestones in Cancer Research and Treatment -- Chemoprevention -- Nutrient-Related Agents -- Phyto Molecules -- Carotenoids -- Secondary Metabolites -- Molecularly Targeted Agents -- Hormonal Prevention -- Finasteride -- Tumor Microenvironment -- Biologic Transduction Pathways -- Peptide Drug -- Bacillus Calmette-Guérin (BCG) -- Hepatitis B -- Human Papillomavirus -- Oral Contraceptives -- The Major Advancement in Cancer Research and Treatment -- Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) -- Artificial Intelligence (AI) -- Robotic Surgery -- Telemedicine and Telehealth -- Infinium Assay -- Cryo-Electron Microscopy (Cryo-EM) -- Conclusion -- References. 7 Cancer Statistics: Geographical and Racial Disparities -- Introduction -- Statistics of Different Types of Cancers in the World -- Statistics of Different Types of Cancers in India -- Statistics of Cancer in Different Racial Groups -- References -- 8 A Comprehensive Overview of Various Cancer Types and Their Progression -- Introduction -- Breast Cancer -- Gene Involved in Aggressive Breast Cancer Progression -- STAT Influence on the TNBC -- Ovarian Cancer -- Lung Cancer -- Non-Small Cell Lung Cancer Signaling Pathway -- PI3K/AKT/mTOR Signaling Pathway -- Pancreatic Cancer -- K-Ras Oncogenic Signaling Pathway -- Wnt/β-Catenin Signaling Pathway -- Childhood Cancer -- Colorectal Cancer -- Wnt-β-Catenine Pathway -- PI3K/Akt/mTOR Signaling Pathways -- Renal Cancer -- PI3K/AKT/mTOR Pathway -- Wnt/β-Catenin Signaling -- Prostate Cancer -- Wnt/β-Catenin Signaling -- PI3-AKT Signaling Pathway -- Conclusion -- References -- 9 Strategies of Early Diagnosis of Cancers -- Introduction -- Characteristics of Cancer -- Progressive Proliferating Signaling -- Inhibiting Apoptosis -- Eluding Growth Inhibitors -- Cancer Screening and Different Markers for Early Cancer Detection -- Early Diagnostic -- Screening -- Constraints of Screening -- Biomarkers -- DNA Methylation -- Blood Biomarkers -- Tumor Biomarkers -- P53 Biomarker -- Scanning and Imaging Tests for Diagnosis of Cancer -- Pap Smear and Human Papillomavirus Testing -- Types of Scanning and Imaging Techniques Used for Diagnosis of Cancer -- X-Ray -- Computed Tomography (CT) -- Mammogram -- Ultrasound -- Magnetic Resonance Imaging (MRI) -- Nuclear Medicine Scan -- PET (Positron Emission Tomography) Scan -- Bone Scans -- MUGA Scans -- Conclusion -- References -- 10 Advancement in Cancer Modeling System: Latest Developments and Trends in Cancer Research and Healthcare Interventions -- Introduction. Historical Aspect of the Cancer Model System: Where It Started? -- What Method Should Be Used to Construct the Cancer Models? -- Conceptual Models -- Agent-Based Models, or ABMs -- Deterministic Models -- Machine Learning (ML) -- What Models Can Address? -- Tumor Growth Models -- Drug Dynamics and PKPD Models (Intra-Tumoral Biodistribution) -- Modeling Tumor Heterogeneity -- Tumor Microenvironment and Immune Interactions -- Examples of Specific Modeling Strategies -- Predator-Prey Models -- Evolutionary Game Theory -- Dynamic Precision Medicine -- An Insight into Cancer Model System -- In Vitro Models -- Cell Lines -- Emerging Trends in in Vitro Research -- Vascularization -- Organs on Chip -- Organoids -- In Vivo Models -- Patient-Derived Xenograft -- Genetically Engineered Mouse Models (GEMMs) -- Drosophila Melanogaster -- Pig Cancer Model -- Zebrafish -- Computational Models -- Conclusion -- References -- 11 Point of Care Molecular Diagnostics in Cancer -- Introduction -- Limitations of PoCs -- References -- 12 Genetics of Cancer: Past, Present, and Future -- Introduction -- Cancer Genetics in Past -- Present -- Future Perspectives in Cancer Genetics -- References -- 13 Mechanisms of Oncogenesis -- References -- 14 Recent Developments in Cancer Detection and Treatment -- Introduction -- Recent Advancements in Cancer Detection -- Recent Advancements in Cancer Treatments -- Conclusion -- References -- 15 Circadian Rhythms and Their Association with Cancer Development -- Introduction -- Circadian Clock Genes -- Circadian Clock and Cancer -- Core Circadian Genes and Hallmarks of Cancer -- Cell Proliferation -- Cancer Cell Signaling -- Apoptosis -- Cancer Cell Metabolism -- DNA Damage -- Conclusion -- References -- 16 Advances in Cancer Pain Management -- Introduction -- Pain Definitions -- Pain Classification and Pathophysiology -- Nociceptive Pain. Neuropathic Pain. |
| Record Nr. | UNINA-9910861093203321 |
Sobti R. C
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| Singapore : , : Springer, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Modulation of Oxidative Stress in Heart Disease [[electronic resource] /] / edited by Sajal Chakraborti, Naranjan S. Dhalla, Madhu Dikshit, Nirmal K. Ganguly
| Modulation of Oxidative Stress in Heart Disease [[electronic resource] /] / edited by Sajal Chakraborti, Naranjan S. Dhalla, Madhu Dikshit, Nirmal K. Ganguly |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (XIII, 686 p. 114 illus., 100 illus. in color.) |
| Disciplina | 571.9453 |
| Soggetto topico |
Oxidative stress
Cardiovascular system Cardiology Cell physiology Biochemistry Biomedical engineering Oxidative Stress Cardiovascular Biology Cell Physiology Biochemistry, general Biomedical Engineering/Biotechnology Estrès (Psicologia) Malalties del cor |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 981-13-8946-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910373918403321 |
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oxidative Stress in Heart Diseases [[electronic resource] /] / edited by Sajal Chakraborti, Naranjan S Dhalla, Nirmal K Ganguly, Madhu Dikshit
| Oxidative Stress in Heart Diseases [[electronic resource] /] / edited by Sajal Chakraborti, Naranjan S Dhalla, Nirmal K Ganguly, Madhu Dikshit |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (XIII, 596 p. 66 illus.) |
| Disciplina | 571.6 |
| Soggetto topico |
Cell biology
Cardiology Biochemistry Biomedical engineering Health promotion Cell physiology Cell Biology Biochemistry, general Biomedical Engineering/Biotechnology Health Promotion and Disease Prevention Cell Physiology Estrès oxidatiu Malalties del cor |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 981-13-8273-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | I. Role of Oxidative Stress in Heart Diseases -- 1. J.L Johnson. Laboratory of cardiovascular pathology, School of Clinical Sciences, University of Bristol, Bristol. UK -- 2. M.A.Srivastava, Department of Physiology, McGill University, Canada -- 3. P. Balakumar. Pharmacology Unit, AIMST University, Semeling 08100 Bedong, Kedah Darul Aman, Malaysia -- 4. K. B Pasumarthi. Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada -- 5. B. Turan. Department of Biophysics, Ankara University, Faculty of Medicine, Ankara,Turkey -- 6. Z. Xie. Marshall Institute of Interdisciplinary Research, Marshall University, Huntington,WV, USA -- 7. T. L. Haas. Angiogenesis Research Group, School of Health Sciences, York University,Toronto, Canada -- 8. A. Kukol. School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK -- 9. N.S.Dhalla, Cardiovascular Research Institute, University of Manitoba, Winnipeg, Canada -- 10. A.K.Srivastava. Cell Signalling laboratory, McGill University, Canada -- 11. S.Chakraborti, University of Kalyani, Kalyani 741235, West Bengal, India -- 12. S.Goswami, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India -- 13. C.C.Kartha, Rajiv Gandhi Institute of Biotechnology, Thiruvanatapuram, India -- 14. S.K.Malick, Department of Pharmacology. AIIMS, New Delhi, India -- 15. S.Chatterjee, Anna University, Chennai, India -- 16. N.Mahapatra, IIT-Madras, Chennai, India -- 17. R. Bhunya, Department of Biochemistry and Biophysicvs, University of kalyani, West Bengal, India -- 18. S.Nandi, North Est Hill University, Meghalaya, India -- 19. N.K.Ganguly, Sir gangaram Hospital, New Delhi -- 20. M.Dixit, CSIR-CDR, -Lucknow, India -- 21. A.D.Abell, University of Adelaide, Australia -- 22. Chava Kimchi Sarfaty, Centre for Biologics Evaluation and Research, Foodand Drug Administration, Bethesda, Maryland, USA -- 23. B. Furhman, Technion Faculty of Medicine and Ramban Medical Center, Hiafa, Israel -- 24. R.F.Gerlach, Department of Physiology, University of Sao Paulo, Brazil -- 25.T.L.Haas, School of Kinesiology and Health Sciences, York University, Toronto, Canada -- 26. B. Mittal, Department of Genetics. Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttap Pradesh, India -- 27. Richard Schulz, Department of Pedfiatrics, University of Alberta, Canada -- 28. Bodh J Jugdutt, Mackenzie Haeth Sciences Centre, Division of Cardiology, University of Alberta, Canada -- 29. Vibha Rani, Jaypee Institute of Information Technology, Noida, Uttar Pradesh, India -- 34. Veena Dhawan, Department of Experimental Medicine and Biotechnology,PGIMER,Chandigarh, India -- 30. Surekha Rani, Department of Genetics, Osmania University, Hyderabad, Telengana State, India. |
| Record Nr. | UNINA-9910373919303321 |
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oxidative Stress in Lung Diseases [[electronic resource] ] : Volume 2 / / edited by Sajal Chakraborti, Narasimham L. Parinandi, Rita Ghosh, Nirmal K. Ganguly, Tapati Chakraborti
| Oxidative Stress in Lung Diseases [[electronic resource] ] : Volume 2 / / edited by Sajal Chakraborti, Narasimham L. Parinandi, Rita Ghosh, Nirmal K. Ganguly, Tapati Chakraborti |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020 |
| Descrizione fisica | 1 online resource (xvi, 488 pages) : illustrations |
| Disciplina | 616.24 |
| Soggetto topico |
Oxidative stress
Respiratory organs—Diseases Medical biochemistry Biomedical engineering Oxidative Stress Pneumology/Respiratory System Medical Biochemistry Biomedical Engineering/Biotechnology |
| ISBN | 981-329-366-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part A -- Chapter 1. The effects of oxidative stress on the pulmonary surfactant and the role of lipids in this scenario -- Chapter 2. Oxidative stress in experimental models of acute lung injury -- Chapter 3. Potential of mesenchymal stem cells in modulating oxidative stress in the management of lung diseases -- Chapter 4. Role of NADPH oxidase induced oxidative stress in matrix metalloprotease-mediated lung diseases -- Chapter 5. Oxidative stress mechanisms in the pathogenesis of environmental lung diseases -- Part B -- Chapter 6. Oxidative stress induced mitochondrial dysfunction and asthma -- Chapter 7. Regulation of antioxidant Nrf2 signaling, an important pathway in COPD -- Chapter 8. Role of smoke-induced oxidative stress in pathogenesis of chronic obstructive pulmonary disease -- Chapter 9. Oxidative stress in obstructive and restrictive lung diseases -- Chapter 10. The use of ozone as redox modulator in the treatment of the chronic obstructive pulmonary disease -- Chapter 11. TRP channels, oxidative stress and chronic obstructive pulmonary disease -- Chapter 12. Paraquat induced oxidative stress and lung inflammation -- Chapter 13. Environmental, occupational and cancer drug induced oxidative stress in lung fibrosis -- Part C -- Chapter 14. Respiratory syncytial virus-induced oxidative stress in lung pathogenesis -- Chapter 15. Reactive oxygen species: Friends or foes of lung cancer? -- Chapter 16. Roles of long non-coding RNAs in lung cancer -- Chapter 17. modulator of therapeutic response in non small cell lung carcinoma -- Chapter 18. old story, new modalities!.Part D -- Chapter 19. Oxidative stress and therapeutic development in lung cancer -- Chapter 20. Regulation of oxidative stress by nitric oxide defines lung development and Diseases -- Chapter 21. Epidermal growth factor receptor: promising targets for non-small cell lung cancer -- Chapter 22. Oxygenated lipid products in COPD and asthma: a clinical picture. . |
| Record Nr. | UNINA-9910367257903321 |
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Studies on Respiratory Disorders / / edited by Nirmal K. Ganguly, Surinder K. Jindal, Shyam Biswal, Peter J. Barnes, Ruby Pawankar
| Studies on Respiratory Disorders / / edited by Nirmal K. Ganguly, Surinder K. Jindal, Shyam Biswal, Peter J. Barnes, Ruby Pawankar |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Humana, , 2014 |
| Descrizione fisica | 1 online resource (396 p.) |
| Disciplina | 616.2 |
| Collana | Oxidative Stress in Applied Basic Research and Clinical Practice |
| Soggetto topico |
Oxidative stress
Cell biology Respiratory organs—Diseases Oxidative Stress Cell Biology Pneumology/Respiratory System |
| ISBN | 1-4939-0497-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction to oxidative stress and anti-oxidant therapy -- Role of reactive oxygen and nitrogen species in respiratory diseases: general considerations -- Role of exhaled biomarkers volatiles and exhaled breath condensate -- Pulmonary infections and oxidative injury -- Role of reactive oxygen species in causing acute lung injury -- Free radicals in pulmonary tuberculosis -- Oxidative injury caused by smoking and air-pollution -- Oxidative stress in chronic obstructive pulmonary disease -- Oxidative stress in asthma and allergic disease -- Oxygen free radicals in pulmonary hypertension -- Pulmonary fibrosis and oxidative stress -- Oxidant injury in sarcoidosis and other granulomatous disorders -- Oxidative stress in lung cancer -- Pulmonary toxicity from drugs, heavy metals and other poisonings – oxidant injury and role of anti-oxidants -- Oxidative stress and respiratory muscle dysfunction -- The critical role of Nrf2 -- Development of novel antioxidants -- Asbestosis. |
| Record Nr. | UNINA-9910298338003321 |
| New York, NY : , : Springer New York : , : Imprint : Humana, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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