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Handbook on the toxicology of metals / / Gunnar F. Nordberg, Bruce A. Fowler, Monica Nordberg, editors
| Handbook on the toxicology of metals / / Gunnar F. Nordberg, Bruce A. Fowler, Monica Nordberg, editors |
| Edizione | [Fourth edition.] |
| Pubbl/distr/stampa | London, England : , : Academic Press, , 2015 |
| Descrizione fisica | 1 online resource (1544 p.) |
| Disciplina | 615.9/253 |
| Soggetto topico | Metals - Toxicology |
| Soggetto genere / forma | Electronic books. |
| ISBN | 0-12-397339-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
e9780444594532v1; Front Cover; Handbook on theToxicology of Metals; Copyright; Preface; Short Contents; Full Contents; List of Contributors; List of Reviewers; Volume I -General Considerations; Chapter 1 -Toxicology of Metals: Overview, Definitions, Concepts, and Trends; 1 METAL EXPOSURES AND GLOBAL BURDEN OF DISEASE; 2 INTERNATIONAL HISTORICAL PERSPECTIVES ON RISKS OF HEALTH EFFECTS OF METALS; 3 METAL POISONING AND OTHER HUMAN HEALTH EFFECTS; 4 HUMAN EXPOSURES TO METALLIC COMPOUNDS, RISK ASSESSMENT, AND PREVENTION; References
Chapter 2 - General Chemistry, Sampling, Analytical Methods, and Speciation*1 DEFINITION OF METALS; 2 THE PERIODIC TABLE; 3 COMPOUNDS OF METALLIC ELEMENTS; 4 SOLUBILITY; 5 PROPERTIES OF METAL IONS; 6 OTHER ASPECTS OF METAL CHEMISTRY OF BIOLOGICAL AND TOXICOLOGICAL INTEREST; 7 METALLOMICS, TOTAL ELEMENT ANALYSIS, AND ELEMENTAL SPECIATION; 8 SAMPLING AND SAMPLE PREPARATION; 9 SEPARATION TECHNIQUES; 10 DETECTION METHODS; 11 CALIBRATION; 12 REFERENCE MATERIALS; 13 QUALITY ASSURANCE; 14 CONCLUSIONS; References; Chapter 3 - Routes of Exposure, Dose, and Toxicokinetics of Metals*; 1 INTRODUCTION 2 EXPOSURE3 DEPOSITION AND ABSORPTION; 4 TRANSPORT, BIOTRANSFORMATION, AND DISTRIBUTION; 5 PATHWAYS AND MECHANISMS OF EXCRETION; 6 TOXICOKINETIC MODELS AND THEIR USE IN ESTABLISHING DOSE-RESPONSE AND DOSE-EFFECT RELATIONSHIPS; 7 USE OF INDICATOR MEDIA FOR ESTIMATING EXPOSURE OR CRITICAL ORGAN CONCENTRATION; References; Chapter 4 - Toxicity of Metal and Metal Oxide Nanoparticles; 1 METAL AND METAL OXIDE NANOPARTICLES; 2 PRINCIPLES OF NANOPARTICLE-INDUCED TOXICITY; 3 PHYSICOCHEMICAL CHARACTERIZATION; 4 METHODS FOR TOXICITY TESTING OF NANOPARTICLES; 5 GOLD NANOPARTICLES; 6 SILVER NANOPARTICLES 7 PLATINUM AND PALLADIUM NANOPARTICLES8 ALUMINUM AND ALUMINUM OXIDE NANOPARTICLES; 9 COPPER AND COPPER OXIDE NANOPARTICLES; 10 NICKEL AND NICKEL OXIDE NANOPARTICLES; 11 IRON OXIDE NANOPARTICLES; 12 TITANIUM DIOXIDE NANOPARTICLES; 13 ZINC OXIDE NANOPARTICLES; 14 CERIUM OXIDE NANOPARTICLES; 15 SILICON DIOXIDE OR SILICA NANOPARTICLES; 16 SEMICONDUCTOR NANOCRYSTALS; 17 CONCLUDING REMARKS; References; Chapter 5 - Toxicity of Metals Released from Implanted Medical Devices; 1 BACKGROUND; 2 TOXICOLOGICAL ISSUES ASSOCIATED WITH METAL RELEASE FROM SPECIFIC TYPES OF IMPLANTED MEDICAL DEVICES 3 CHALLENGES AND FUTURE DIRECTIONSReferences; Chapter 6 - Toxic Metals in Food; 1 INTRODUCTION; 2 CADMIUM; 3 LEAD; 4 MERCURY; 5 ARSENIC; 6 HEALTH-BASED GUIDANCE VALUES AND BENCHMARK DOSE (LOWER CONFIDENCE LIMIT) FOR CADMIUM, MERCURY, LEAD, AND ARSENIC; 7 FOOD CONTAMINATION FROM PACKAGING; 8 CONCLUSION; References; Chapter 7 - Exposure Assessment, Forward and Reverse Dosimetry*; 1 INTRODUCTION; 2 GENERAL PRINCIPLES; 3 PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING; 4 BIOMONITORING AND ITS INTERPRETATION; 5 HUMAN PBPK TOOL KIT DEVELOPMENT: THE GENERAL APPROACH; 6 CONCLUSIONS; References Chapter 8 - Biological Monitoring and Biomarkers |
| Record Nr. | UNINA-9910458724903321 |
| London, England : , : Academic Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Handbook on the toxicology of metals / / Gunnar F. Nordberg, Bruce A. Fowler, Monica Nordberg, editors
| Handbook on the toxicology of metals / / Gunnar F. Nordberg, Bruce A. Fowler, Monica Nordberg, editors |
| Edizione | [Fourth edition.] |
| Pubbl/distr/stampa | London, England : , : Academic Press, , 2015 |
| Descrizione fisica | 1 online resource (1544 p.) |
| Disciplina | 615.9/253 |
| Soggetto topico | Metals - Toxicology |
| ISBN | 0-12-397339-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
e9780444594532v1; Front Cover; Handbook on theToxicology of Metals; Copyright; Preface; Short Contents; Full Contents; List of Contributors; List of Reviewers; Volume I -General Considerations; Chapter 1 -Toxicology of Metals: Overview, Definitions, Concepts, and Trends; 1 METAL EXPOSURES AND GLOBAL BURDEN OF DISEASE; 2 INTERNATIONAL HISTORICAL PERSPECTIVES ON RISKS OF HEALTH EFFECTS OF METALS; 3 METAL POISONING AND OTHER HUMAN HEALTH EFFECTS; 4 HUMAN EXPOSURES TO METALLIC COMPOUNDS, RISK ASSESSMENT, AND PREVENTION; References
Chapter 2 - General Chemistry, Sampling, Analytical Methods, and Speciation*1 DEFINITION OF METALS; 2 THE PERIODIC TABLE; 3 COMPOUNDS OF METALLIC ELEMENTS; 4 SOLUBILITY; 5 PROPERTIES OF METAL IONS; 6 OTHER ASPECTS OF METAL CHEMISTRY OF BIOLOGICAL AND TOXICOLOGICAL INTEREST; 7 METALLOMICS, TOTAL ELEMENT ANALYSIS, AND ELEMENTAL SPECIATION; 8 SAMPLING AND SAMPLE PREPARATION; 9 SEPARATION TECHNIQUES; 10 DETECTION METHODS; 11 CALIBRATION; 12 REFERENCE MATERIALS; 13 QUALITY ASSURANCE; 14 CONCLUSIONS; References; Chapter 3 - Routes of Exposure, Dose, and Toxicokinetics of Metals*; 1 INTRODUCTION 2 EXPOSURE3 DEPOSITION AND ABSORPTION; 4 TRANSPORT, BIOTRANSFORMATION, AND DISTRIBUTION; 5 PATHWAYS AND MECHANISMS OF EXCRETION; 6 TOXICOKINETIC MODELS AND THEIR USE IN ESTABLISHING DOSE-RESPONSE AND DOSE-EFFECT RELATIONSHIPS; 7 USE OF INDICATOR MEDIA FOR ESTIMATING EXPOSURE OR CRITICAL ORGAN CONCENTRATION; References; Chapter 4 - Toxicity of Metal and Metal Oxide Nanoparticles; 1 METAL AND METAL OXIDE NANOPARTICLES; 2 PRINCIPLES OF NANOPARTICLE-INDUCED TOXICITY; 3 PHYSICOCHEMICAL CHARACTERIZATION; 4 METHODS FOR TOXICITY TESTING OF NANOPARTICLES; 5 GOLD NANOPARTICLES; 6 SILVER NANOPARTICLES 7 PLATINUM AND PALLADIUM NANOPARTICLES8 ALUMINUM AND ALUMINUM OXIDE NANOPARTICLES; 9 COPPER AND COPPER OXIDE NANOPARTICLES; 10 NICKEL AND NICKEL OXIDE NANOPARTICLES; 11 IRON OXIDE NANOPARTICLES; 12 TITANIUM DIOXIDE NANOPARTICLES; 13 ZINC OXIDE NANOPARTICLES; 14 CERIUM OXIDE NANOPARTICLES; 15 SILICON DIOXIDE OR SILICA NANOPARTICLES; 16 SEMICONDUCTOR NANOCRYSTALS; 17 CONCLUDING REMARKS; References; Chapter 5 - Toxicity of Metals Released from Implanted Medical Devices; 1 BACKGROUND; 2 TOXICOLOGICAL ISSUES ASSOCIATED WITH METAL RELEASE FROM SPECIFIC TYPES OF IMPLANTED MEDICAL DEVICES 3 CHALLENGES AND FUTURE DIRECTIONSReferences; Chapter 6 - Toxic Metals in Food; 1 INTRODUCTION; 2 CADMIUM; 3 LEAD; 4 MERCURY; 5 ARSENIC; 6 HEALTH-BASED GUIDANCE VALUES AND BENCHMARK DOSE (LOWER CONFIDENCE LIMIT) FOR CADMIUM, MERCURY, LEAD, AND ARSENIC; 7 FOOD CONTAMINATION FROM PACKAGING; 8 CONCLUSION; References; Chapter 7 - Exposure Assessment, Forward and Reverse Dosimetry*; 1 INTRODUCTION; 2 GENERAL PRINCIPLES; 3 PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING; 4 BIOMONITORING AND ITS INTERPRETATION; 5 HUMAN PBPK TOOL KIT DEVELOPMENT: THE GENERAL APPROACH; 6 CONCLUSIONS; References Chapter 8 - Biological Monitoring and Biomarkers |
| Record Nr. | UNINA-9910791147303321 |
| London, England : , : Academic Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Handbook on the toxicology of metals / / Gunnar F. Nordberg, Bruce A. Fowler, Monica Nordberg, editors
| Handbook on the toxicology of metals / / Gunnar F. Nordberg, Bruce A. Fowler, Monica Nordberg, editors |
| Edizione | [Fourth edition.] |
| Pubbl/distr/stampa | London, England : , : Academic Press, , 2015 |
| Descrizione fisica | 1 online resource (1544 p.) |
| Disciplina | 615.9/253 |
| Soggetto topico | Metals - Toxicology |
| ISBN | 0-12-397339-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
e9780444594532v1; Front Cover; Handbook on theToxicology of Metals; Copyright; Preface; Short Contents; Full Contents; List of Contributors; List of Reviewers; Volume I -General Considerations; Chapter 1 -Toxicology of Metals: Overview, Definitions, Concepts, and Trends; 1 METAL EXPOSURES AND GLOBAL BURDEN OF DISEASE; 2 INTERNATIONAL HISTORICAL PERSPECTIVES ON RISKS OF HEALTH EFFECTS OF METALS; 3 METAL POISONING AND OTHER HUMAN HEALTH EFFECTS; 4 HUMAN EXPOSURES TO METALLIC COMPOUNDS, RISK ASSESSMENT, AND PREVENTION; References
Chapter 2 - General Chemistry, Sampling, Analytical Methods, and Speciation*1 DEFINITION OF METALS; 2 THE PERIODIC TABLE; 3 COMPOUNDS OF METALLIC ELEMENTS; 4 SOLUBILITY; 5 PROPERTIES OF METAL IONS; 6 OTHER ASPECTS OF METAL CHEMISTRY OF BIOLOGICAL AND TOXICOLOGICAL INTEREST; 7 METALLOMICS, TOTAL ELEMENT ANALYSIS, AND ELEMENTAL SPECIATION; 8 SAMPLING AND SAMPLE PREPARATION; 9 SEPARATION TECHNIQUES; 10 DETECTION METHODS; 11 CALIBRATION; 12 REFERENCE MATERIALS; 13 QUALITY ASSURANCE; 14 CONCLUSIONS; References; Chapter 3 - Routes of Exposure, Dose, and Toxicokinetics of Metals*; 1 INTRODUCTION 2 EXPOSURE3 DEPOSITION AND ABSORPTION; 4 TRANSPORT, BIOTRANSFORMATION, AND DISTRIBUTION; 5 PATHWAYS AND MECHANISMS OF EXCRETION; 6 TOXICOKINETIC MODELS AND THEIR USE IN ESTABLISHING DOSE-RESPONSE AND DOSE-EFFECT RELATIONSHIPS; 7 USE OF INDICATOR MEDIA FOR ESTIMATING EXPOSURE OR CRITICAL ORGAN CONCENTRATION; References; Chapter 4 - Toxicity of Metal and Metal Oxide Nanoparticles; 1 METAL AND METAL OXIDE NANOPARTICLES; 2 PRINCIPLES OF NANOPARTICLE-INDUCED TOXICITY; 3 PHYSICOCHEMICAL CHARACTERIZATION; 4 METHODS FOR TOXICITY TESTING OF NANOPARTICLES; 5 GOLD NANOPARTICLES; 6 SILVER NANOPARTICLES 7 PLATINUM AND PALLADIUM NANOPARTICLES8 ALUMINUM AND ALUMINUM OXIDE NANOPARTICLES; 9 COPPER AND COPPER OXIDE NANOPARTICLES; 10 NICKEL AND NICKEL OXIDE NANOPARTICLES; 11 IRON OXIDE NANOPARTICLES; 12 TITANIUM DIOXIDE NANOPARTICLES; 13 ZINC OXIDE NANOPARTICLES; 14 CERIUM OXIDE NANOPARTICLES; 15 SILICON DIOXIDE OR SILICA NANOPARTICLES; 16 SEMICONDUCTOR NANOCRYSTALS; 17 CONCLUDING REMARKS; References; Chapter 5 - Toxicity of Metals Released from Implanted Medical Devices; 1 BACKGROUND; 2 TOXICOLOGICAL ISSUES ASSOCIATED WITH METAL RELEASE FROM SPECIFIC TYPES OF IMPLANTED MEDICAL DEVICES 3 CHALLENGES AND FUTURE DIRECTIONSReferences; Chapter 6 - Toxic Metals in Food; 1 INTRODUCTION; 2 CADMIUM; 3 LEAD; 4 MERCURY; 5 ARSENIC; 6 HEALTH-BASED GUIDANCE VALUES AND BENCHMARK DOSE (LOWER CONFIDENCE LIMIT) FOR CADMIUM, MERCURY, LEAD, AND ARSENIC; 7 FOOD CONTAMINATION FROM PACKAGING; 8 CONCLUSION; References; Chapter 7 - Exposure Assessment, Forward and Reverse Dosimetry*; 1 INTRODUCTION; 2 GENERAL PRINCIPLES; 3 PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING; 4 BIOMONITORING AND ITS INTERPRETATION; 5 HUMAN PBPK TOOL KIT DEVELOPMENT: THE GENERAL APPROACH; 6 CONCLUSIONS; References Chapter 8 - Biological Monitoring and Biomarkers |
| Record Nr. | UNINA-9910813104503321 |
| London, England : , : Academic Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Risk assessment for human metal exposures : mode of action and kinetic approaches / / Gunnar F. Nordberg, Bruce A. Fowler
| Risk assessment for human metal exposures : mode of action and kinetic approaches / / Gunnar F. Nordberg, Bruce A. Fowler |
| Autore | Nordberg Gunnar |
| Edizione | [First edition.] |
| Pubbl/distr/stampa | London, United Kingdom : , : Academic Press, an imprint of Elsevier, , [2019] |
| Descrizione fisica | 1 online resource (350 pages) |
| Disciplina | 615.9253 |
| Soggetto topico | Metals - Toxicology |
| ISBN |
0-12-804268-0
0-12-804227-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Metal exposures and human health -- historical development, current importance, and toxicological concepts for prevention -- Exposure, internal dose, and toxicokinesis (TK) -- Biomonitoring, mode of action (MOA), target dose, and adverse outcome pathways (AOPs) -- Hazard identification and assessment -- Dose-effect and dose-response assessment -- Dose-response for essential metals and the evaluation of mixed exposures -- Applied risk assessment, hazard assessment, and risk management -- Examples of risk assessments of human metal exposures and the need for mode of action (MOA), toxicokinetic-toxicodynamic (TKTD) modeling, and adverse outcome pathways (AOPs). |
| Record Nr. | UNINA-9910583026303321 |
Nordberg Gunnar
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| London, United Kingdom : , : Academic Press, an imprint of Elsevier, , [2019] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||