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Drugs and the older population [[electronic resource] /] / editors, Peter Crome, Gary Ford
| Drugs and the older population [[electronic resource] /] / editors, Peter Crome, Gary Ford |
| Pubbl/distr/stampa | London, : Imperial College Press |
| Descrizione fisica | 1 online resource (728 p.) |
| Disciplina | 615.5/8/0846 |
| Altri autori (Persone) |
CromePeter
FordGary (Gary A.) |
| Soggetto topico | Geriatric pharmacology |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-86094-648-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Foreword; Introduction; List of Contributors; Contents; CHAPTER 1 Pharmacoepidemiology and the Elderly; Introduction; Types of Pharmacoepidemiologic Studies; Adverse and Beneficial Effects of Drug Therapy; Drug Utilization Studies; Antipsychotic Drugs; Thrombolysis in Acute Myocardial Infarction; Opioids for Pain Management in Cancer; Pharmacoeconomic Studies; Quality-of-life Studies; Importance of Postmarketing Drug Surveillance; Principles of Pharmacoepidemiologic Research; The Frequency of Adverse Drug Events; Study Designs; Observational Studies; Ecologic (correlational) Studies
Cross-sectional StudiesCase-control Studies; Cohort Studies; Common Types of Error in Observational Studies; Experimental Studies; Measures of Association; Data Sources for Observational Pharmacoepidemiologic Studies; Future Research Directions; References; CHAPTER 2 Drug Use and Older People: Sociological Perspectives; Introduction; The Role of Biomedicine; Doctors and the Elderly; Social Characteristics and Patterns of Drug Use; Drugs and the Culture of Ageing; Empowering Older People: The Role of Self-health Care and Consumerism; References CHAPTER 3 Economic Aspects of Drugs and Older PeopleIntroduction; What is Health Economics?; Demographic Trends; Life Expectancy; Prevalence of Acute and Chronic Ill-Health; GP Consultation Rates; Prescription Items Dispensed; Prescription Costs; Health Economics; Ten Common Mistakes in Health Economics; Methods of Analysis; Costs; Where Costs Fall; The Type of Costs; Outcomes; Sensitivity Analysis; Different Perspective; References; CHAPTER 4 Pharmacokinetics; Introduction; Drugs and the Older Population; Pharmacokinetics, Pharmacodynamics and Drug Effects Factors Influencing Pharmacokinetics in Older PeopleAge Related Changes in Drug Absorption and Bioavailability; Absorption; First Pass Metabolism and Bioavailability; Age Related Changes in Drug Distribution; Volume of Distribution; Protein Binding; Age Related Changes in Drug Clearance; Age Related Changes in Renal Excretion; Age Related Changes in Hepatic Clearance; Phase 1 Metabolism and Ageing; Factors Contributing to Age Related Reductions in Liver Metabolism; Phase 2 Metabolism and Ageing; Frailty, Disease and Drug Metabolism; Frailty; Disease; Conclusions; Research Work to Date Directions for Future ResearchReferences; CHAPTER 5 Pharmacodynamics; Introduction; Important Age-associated Pharmacodynamic Changes; Mechanisms of Pharmacodynamic Changes; Cardiovascular Drugs; Vascular Responses; Blood Pressure Lowering Drugs; Central Nervous System Drugs; Conclusions and Suggestions for Future Research; References; CHAPTER 6 Adverse Drug Reactions; Introduction; Definitions; ADRs and Hospital Admission; Studies in Hospital and Nursing Homes; Studies in Ambulatory Settings; Causes; Class of Drugs; Age; Number of Drugs; Consequences and Outcome Reports to Drug Regulatory Authorities |
| Record Nr. | UNINA-9910449881403321 |
| London, : Imperial College Press | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Drugs and the older population [[electronic resource] /] / editors, Peter Crome, Gary Ford
| Drugs and the older population [[electronic resource] /] / editors, Peter Crome, Gary Ford |
| Pubbl/distr/stampa | London, : Imperial College Press |
| Descrizione fisica | 1 online resource (728 p.) |
| Disciplina | 615.5/8/0846 |
| Altri autori (Persone) |
CromePeter
FordGary (Gary A.) |
| Soggetto topico | Geriatric pharmacology |
| ISBN | 1-86094-648-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Foreword; Introduction; List of Contributors; Contents; CHAPTER 1 Pharmacoepidemiology and the Elderly; Introduction; Types of Pharmacoepidemiologic Studies; Adverse and Beneficial Effects of Drug Therapy; Drug Utilization Studies; Antipsychotic Drugs; Thrombolysis in Acute Myocardial Infarction; Opioids for Pain Management in Cancer; Pharmacoeconomic Studies; Quality-of-life Studies; Importance of Postmarketing Drug Surveillance; Principles of Pharmacoepidemiologic Research; The Frequency of Adverse Drug Events; Study Designs; Observational Studies; Ecologic (correlational) Studies
Cross-sectional StudiesCase-control Studies; Cohort Studies; Common Types of Error in Observational Studies; Experimental Studies; Measures of Association; Data Sources for Observational Pharmacoepidemiologic Studies; Future Research Directions; References; CHAPTER 2 Drug Use and Older People: Sociological Perspectives; Introduction; The Role of Biomedicine; Doctors and the Elderly; Social Characteristics and Patterns of Drug Use; Drugs and the Culture of Ageing; Empowering Older People: The Role of Self-health Care and Consumerism; References CHAPTER 3 Economic Aspects of Drugs and Older PeopleIntroduction; What is Health Economics?; Demographic Trends; Life Expectancy; Prevalence of Acute and Chronic Ill-Health; GP Consultation Rates; Prescription Items Dispensed; Prescription Costs; Health Economics; Ten Common Mistakes in Health Economics; Methods of Analysis; Costs; Where Costs Fall; The Type of Costs; Outcomes; Sensitivity Analysis; Different Perspective; References; CHAPTER 4 Pharmacokinetics; Introduction; Drugs and the Older Population; Pharmacokinetics, Pharmacodynamics and Drug Effects Factors Influencing Pharmacokinetics in Older PeopleAge Related Changes in Drug Absorption and Bioavailability; Absorption; First Pass Metabolism and Bioavailability; Age Related Changes in Drug Distribution; Volume of Distribution; Protein Binding; Age Related Changes in Drug Clearance; Age Related Changes in Renal Excretion; Age Related Changes in Hepatic Clearance; Phase 1 Metabolism and Ageing; Factors Contributing to Age Related Reductions in Liver Metabolism; Phase 2 Metabolism and Ageing; Frailty, Disease and Drug Metabolism; Frailty; Disease; Conclusions; Research Work to Date Directions for Future ResearchReferences; CHAPTER 5 Pharmacodynamics; Introduction; Important Age-associated Pharmacodynamic Changes; Mechanisms of Pharmacodynamic Changes; Cardiovascular Drugs; Vascular Responses; Blood Pressure Lowering Drugs; Central Nervous System Drugs; Conclusions and Suggestions for Future Research; References; CHAPTER 6 Adverse Drug Reactions; Introduction; Definitions; ADRs and Hospital Admission; Studies in Hospital and Nursing Homes; Studies in Ambulatory Settings; Causes; Class of Drugs; Age; Number of Drugs; Consequences and Outcome Reports to Drug Regulatory Authorities |
| Record Nr. | UNINA-9910777328903321 |
| London, : Imperial College Press | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Drugs and the older population / / editors, Peter Crome, Gary Ford
| Drugs and the older population / / editors, Peter Crome, Gary Ford |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | London, : Imperial College Press |
| Descrizione fisica | 1 online resource (728 p.) |
| Disciplina | 615.5/8/0846 |
| Altri autori (Persone) |
CromePeter
FordGary (Gary A.) |
| Soggetto topico | Geriatric pharmacology |
| ISBN | 1-86094-648-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Foreword; Introduction; List of Contributors; Contents; CHAPTER 1 Pharmacoepidemiology and the Elderly; Introduction; Types of Pharmacoepidemiologic Studies; Adverse and Beneficial Effects of Drug Therapy; Drug Utilization Studies; Antipsychotic Drugs; Thrombolysis in Acute Myocardial Infarction; Opioids for Pain Management in Cancer; Pharmacoeconomic Studies; Quality-of-life Studies; Importance of Postmarketing Drug Surveillance; Principles of Pharmacoepidemiologic Research; The Frequency of Adverse Drug Events; Study Designs; Observational Studies; Ecologic (correlational) Studies
Cross-sectional StudiesCase-control Studies; Cohort Studies; Common Types of Error in Observational Studies; Experimental Studies; Measures of Association; Data Sources for Observational Pharmacoepidemiologic Studies; Future Research Directions; References; CHAPTER 2 Drug Use and Older People: Sociological Perspectives; Introduction; The Role of Biomedicine; Doctors and the Elderly; Social Characteristics and Patterns of Drug Use; Drugs and the Culture of Ageing; Empowering Older People: The Role of Self-health Care and Consumerism; References CHAPTER 3 Economic Aspects of Drugs and Older PeopleIntroduction; What is Health Economics?; Demographic Trends; Life Expectancy; Prevalence of Acute and Chronic Ill-Health; GP Consultation Rates; Prescription Items Dispensed; Prescription Costs; Health Economics; Ten Common Mistakes in Health Economics; Methods of Analysis; Costs; Where Costs Fall; The Type of Costs; Outcomes; Sensitivity Analysis; Different Perspective; References; CHAPTER 4 Pharmacokinetics; Introduction; Drugs and the Older Population; Pharmacokinetics, Pharmacodynamics and Drug Effects Factors Influencing Pharmacokinetics in Older PeopleAge Related Changes in Drug Absorption and Bioavailability; Absorption; First Pass Metabolism and Bioavailability; Age Related Changes in Drug Distribution; Volume of Distribution; Protein Binding; Age Related Changes in Drug Clearance; Age Related Changes in Renal Excretion; Age Related Changes in Hepatic Clearance; Phase 1 Metabolism and Ageing; Factors Contributing to Age Related Reductions in Liver Metabolism; Phase 2 Metabolism and Ageing; Frailty, Disease and Drug Metabolism; Frailty; Disease; Conclusions; Research Work to Date Directions for Future ResearchReferences; CHAPTER 5 Pharmacodynamics; Introduction; Important Age-associated Pharmacodynamic Changes; Mechanisms of Pharmacodynamic Changes; Cardiovascular Drugs; Vascular Responses; Blood Pressure Lowering Drugs; Central Nervous System Drugs; Conclusions and Suggestions for Future Research; References; CHAPTER 6 Adverse Drug Reactions; Introduction; Definitions; ADRs and Hospital Admission; Studies in Hospital and Nursing Homes; Studies in Ambulatory Settings; Causes; Class of Drugs; Age; Number of Drugs; Consequences and Outcome Reports to Drug Regulatory Authorities |
| Record Nr. | UNINA-9910810633503321 |
| London, : Imperial College Press | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||