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Bioinformatics for vaccinology [[electronic resource] /] / Darren R. Flower
| Bioinformatics for vaccinology [[electronic resource] /] / Darren R. Flower |
| Autore | Flower Darren R |
| Edizione | [1st edition] |
| Pubbl/distr/stampa | Chichester, West Sussex, England ; ; Hoboken, NJ, : John Wiley & Sons, 2008 |
| Descrizione fisica | 1 online resource (314 p.) |
| Disciplina |
572
615/.3720285 |
| Soggetto topico |
Immunoinformatics
Vaccines - Design - Data processing |
| ISBN |
1-281-93944-7
9786611939441 0-470-69983-3 0-470-69982-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Bioinformatics for Vaccinology; Contents; Preface; Acknowledgements; Exordium; 1 Vaccines: Their place in history; Smallpox in history; Variolation; Variolation in history; Variolation comes to Britain; Lady Mary Wortley Montagu; Variolation and the Sublime Porte; The royal experiment; The boston connection; Variolation takes hold; The Suttonian method; Variolation in Europe; The coming of vaccination; Edward Jenner; Cowpox; Vaccination vindicated; Louis Pasteur; Vaccination becomes a science; Meister, Pasteur and rabies; A vaccine for every disease; In the time of cholera
Haffkine and choleraBubonic plague; The changing face of disease; Almroth wright and typhoid; Tuberculosis, Koch, and Calmette; Vaccine BCG; Poliomyelitis; Salk and Sabin; Diphtheria; Whooping cough; Many diseases, many vaccines; Smallpox: Endgame; Further reading; 2 Vaccines: Need and opportunity; Eradication and reservoirs; The ongoing burden of disease; Lifespans; The evolving nature of disease; Economics, climate and disease; Three threats; Tuberculosis in the 21 st century; HIV and AIDS; Malaria: Then and now; Influenza; Bioterrorism; Vaccines as medicines Vaccines and the pharmaceutical industryMaking vaccines; The coming of the vaccine industry; 3 Vaccines: How they work; Challenging the immune system; The threat from bacteria: Robust, diverse, and endemic; Microbes, diversity and metagenomics; The intrinsic complexity of the bacterial threat; Microbes and humankind; The nature of vaccines; Types of vaccine; Carbohydrate vaccines; Epitopic vaccines; Vaccine delivery; Emerging immunovaccinology; The immune system; Innate immunity; Adaptive immunity; The microbiome and mucosal immunity; Cellular components of immunity; Cellular immunity The T cell repertoireEpitopes: The immunological quantum; The major histocompatibility complex; MHC nomenclature; Peptide binding by the MHC; The structure of the MHC; Antigen presentation; The proteasome; Transporter associated with antigen processing; Class II processing; Seek simplicity and then distrust it; Cross presentation; T cell receptor; T cell activation; Immunological synapse; Signal 1, signal 2, immunodominance; Humoral immunity; Further reading; 4 Vaccines: Data and databases; Making sense of data; Knowledge in a box; The science of -omes and -omics; The proteome Systems biologyThe immunome; Databases and databanks; The relational database; The XML database; The protein universe; Much data, many databases; What proteins do; What proteins are; The amino acid world; The chiral nature of amino acids; Naming the amino acids; The amino acid alphabet; Defining amino acid properties; Size, charge and hydrogen bonding; Hydrophobicity, lipophilicity and partitioning; Understanding partitioning; Charges, ionization, and pka; Many kinds of property; Mapping the world of sequences; Biological sequence databases; Nucleic acid sequence databases Protein sequence databases |
| Record Nr. | UNINA-9910144096903321 |
Flower Darren R
|
||
| Chichester, West Sussex, England ; ; Hoboken, NJ, : John Wiley & Sons, 2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Bioinformatics for vaccinology [[electronic resource] /] / Darren R. Flower
| Bioinformatics for vaccinology [[electronic resource] /] / Darren R. Flower |
| Autore | Flower Darren R |
| Edizione | [1st edition] |
| Pubbl/distr/stampa | Chichester, West Sussex, England ; ; Hoboken, NJ, : John Wiley & Sons, 2008 |
| Descrizione fisica | 1 online resource (314 p.) |
| Disciplina |
572
615/.3720285 |
| Soggetto topico |
Immunoinformatics
Vaccines - Design - Data processing |
| ISBN |
1-281-93944-7
9786611939441 0-470-69983-3 0-470-69982-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Bioinformatics for Vaccinology; Contents; Preface; Acknowledgements; Exordium; 1 Vaccines: Their place in history; Smallpox in history; Variolation; Variolation in history; Variolation comes to Britain; Lady Mary Wortley Montagu; Variolation and the Sublime Porte; The royal experiment; The boston connection; Variolation takes hold; The Suttonian method; Variolation in Europe; The coming of vaccination; Edward Jenner; Cowpox; Vaccination vindicated; Louis Pasteur; Vaccination becomes a science; Meister, Pasteur and rabies; A vaccine for every disease; In the time of cholera
Haffkine and choleraBubonic plague; The changing face of disease; Almroth wright and typhoid; Tuberculosis, Koch, and Calmette; Vaccine BCG; Poliomyelitis; Salk and Sabin; Diphtheria; Whooping cough; Many diseases, many vaccines; Smallpox: Endgame; Further reading; 2 Vaccines: Need and opportunity; Eradication and reservoirs; The ongoing burden of disease; Lifespans; The evolving nature of disease; Economics, climate and disease; Three threats; Tuberculosis in the 21 st century; HIV and AIDS; Malaria: Then and now; Influenza; Bioterrorism; Vaccines as medicines Vaccines and the pharmaceutical industryMaking vaccines; The coming of the vaccine industry; 3 Vaccines: How they work; Challenging the immune system; The threat from bacteria: Robust, diverse, and endemic; Microbes, diversity and metagenomics; The intrinsic complexity of the bacterial threat; Microbes and humankind; The nature of vaccines; Types of vaccine; Carbohydrate vaccines; Epitopic vaccines; Vaccine delivery; Emerging immunovaccinology; The immune system; Innate immunity; Adaptive immunity; The microbiome and mucosal immunity; Cellular components of immunity; Cellular immunity The T cell repertoireEpitopes: The immunological quantum; The major histocompatibility complex; MHC nomenclature; Peptide binding by the MHC; The structure of the MHC; Antigen presentation; The proteasome; Transporter associated with antigen processing; Class II processing; Seek simplicity and then distrust it; Cross presentation; T cell receptor; T cell activation; Immunological synapse; Signal 1, signal 2, immunodominance; Humoral immunity; Further reading; 4 Vaccines: Data and databases; Making sense of data; Knowledge in a box; The science of -omes and -omics; The proteome Systems biologyThe immunome; Databases and databanks; The relational database; The XML database; The protein universe; Much data, many databases; What proteins do; What proteins are; The amino acid world; The chiral nature of amino acids; Naming the amino acids; The amino acid alphabet; Defining amino acid properties; Size, charge and hydrogen bonding; Hydrophobicity, lipophilicity and partitioning; Understanding partitioning; Charges, ionization, and pka; Many kinds of property; Mapping the world of sequences; Biological sequence databases; Nucleic acid sequence databases Protein sequence databases |
| Record Nr. | UNINA-9910830214103321 |
|
Flower Darren R
|
||
| Chichester, West Sussex, England ; ; Hoboken, NJ, : John Wiley & Sons, 2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Bioinformatics for vaccinology / / Darren R. Flower
| Bioinformatics for vaccinology / / Darren R. Flower |
| Autore | Flower Darren R |
| Edizione | [1st edition] |
| Pubbl/distr/stampa | Chichester, West Sussex, England ; ; Hoboken, NJ, : John Wiley & Sons, 2008 |
| Descrizione fisica | 1 online resource (314 p.) |
| Disciplina | 615/.3720285 |
| Soggetto topico |
Immunoinformatics
Vaccines - Design - Data processing |
| ISBN |
9786611939441
9781281939449 1281939447 9780470699836 0470699833 9780470699829 0470699825 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Bioinformatics for Vaccinology; Contents; Preface; Acknowledgements; Exordium; 1 Vaccines: Their place in history; Smallpox in history; Variolation; Variolation in history; Variolation comes to Britain; Lady Mary Wortley Montagu; Variolation and the Sublime Porte; The royal experiment; The boston connection; Variolation takes hold; The Suttonian method; Variolation in Europe; The coming of vaccination; Edward Jenner; Cowpox; Vaccination vindicated; Louis Pasteur; Vaccination becomes a science; Meister, Pasteur and rabies; A vaccine for every disease; In the time of cholera
Haffkine and choleraBubonic plague; The changing face of disease; Almroth wright and typhoid; Tuberculosis, Koch, and Calmette; Vaccine BCG; Poliomyelitis; Salk and Sabin; Diphtheria; Whooping cough; Many diseases, many vaccines; Smallpox: Endgame; Further reading; 2 Vaccines: Need and opportunity; Eradication and reservoirs; The ongoing burden of disease; Lifespans; The evolving nature of disease; Economics, climate and disease; Three threats; Tuberculosis in the 21 st century; HIV and AIDS; Malaria: Then and now; Influenza; Bioterrorism; Vaccines as medicines Vaccines and the pharmaceutical industryMaking vaccines; The coming of the vaccine industry; 3 Vaccines: How they work; Challenging the immune system; The threat from bacteria: Robust, diverse, and endemic; Microbes, diversity and metagenomics; The intrinsic complexity of the bacterial threat; Microbes and humankind; The nature of vaccines; Types of vaccine; Carbohydrate vaccines; Epitopic vaccines; Vaccine delivery; Emerging immunovaccinology; The immune system; Innate immunity; Adaptive immunity; The microbiome and mucosal immunity; Cellular components of immunity; Cellular immunity The T cell repertoireEpitopes: The immunological quantum; The major histocompatibility complex; MHC nomenclature; Peptide binding by the MHC; The structure of the MHC; Antigen presentation; The proteasome; Transporter associated with antigen processing; Class II processing; Seek simplicity and then distrust it; Cross presentation; T cell receptor; T cell activation; Immunological synapse; Signal 1, signal 2, immunodominance; Humoral immunity; Further reading; 4 Vaccines: Data and databases; Making sense of data; Knowledge in a box; The science of -omes and -omics; The proteome Systems biologyThe immunome; Databases and databanks; The relational database; The XML database; The protein universe; Much data, many databases; What proteins do; What proteins are; The amino acid world; The chiral nature of amino acids; Naming the amino acids; The amino acid alphabet; Defining amino acid properties; Size, charge and hydrogen bonding; Hydrophobicity, lipophilicity and partitioning; Understanding partitioning; Charges, ionization, and pka; Many kinds of property; Mapping the world of sequences; Biological sequence databases; Nucleic acid sequence databases Protein sequence databases |
| Record Nr. | UNINA-9910876725903321 |
|
Flower Darren R
|
||
| Chichester, West Sussex, England ; ; Hoboken, NJ, : John Wiley & Sons, 2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||