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Downstream industrial biotechnology [[electronic resource] ] : recovery and purification / / edited by Michael C. Flickinger
| Downstream industrial biotechnology [[electronic resource] ] : recovery and purification / / edited by Michael C. Flickinger |
| Pubbl/distr/stampa | Hoboken, N.J., : John Wiley & Sons Inc., 2013 |
| Descrizione fisica | 1 online resource (875 p.) |
| Disciplina | 660.6 |
| Altri autori (Persone) | FlickingerMichael C |
| Soggetto topico | Biotechnology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-118-61898-X
1-118-61912-9 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | pt. I. Introduction -- pt. II. Downstream recovery of cells and protein capture -- pt. III. Process development in downstream purification -- pt. IV. Equipment design for downstream recovery and protein purification -- pt. V. Downstream cGMP operations -- pt. VI. Biopharmaceutical facility validation -- pt. VII. FDA cGMP regulatory compliance. |
| Record Nr. | UNINA-9910463787903321 |
| Hoboken, N.J., : John Wiley & Sons Inc., 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Downstream industrial biotechnology [[electronic resource] ] : recovery and purification / / edited by Michael C. Flickinger
| Downstream industrial biotechnology [[electronic resource] ] : recovery and purification / / edited by Michael C. Flickinger |
| Pubbl/distr/stampa | Hoboken, N.J., : John Wiley & Sons Inc., 2013 |
| Descrizione fisica | 1 online resource (875 p.) |
| Disciplina | 660.6 |
| Altri autori (Persone) | FlickingerMichael C |
| Soggetto topico | Biotechnology |
| ISBN |
1-118-61898-X
1-118-61912-9 |
| Classificazione | SCI010000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | pt. I. Introduction -- pt. II. Downstream recovery of cells and protein capture -- pt. III. Process development in downstream purification -- pt. IV. Equipment design for downstream recovery and protein purification -- pt. V. Downstream cGMP operations -- pt. VI. Biopharmaceutical facility validation -- pt. VII. FDA cGMP regulatory compliance. |
| Record Nr. | UNINA-9910787324103321 |
| Hoboken, N.J., : John Wiley & Sons Inc., 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Downstream industrial biotechnology : recovery and purification / / edited by Michael C. Flickinger
| Downstream industrial biotechnology : recovery and purification / / edited by Michael C. Flickinger |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, N.J., : John Wiley & Sons Inc., 2013 |
| Descrizione fisica | 1 online resource (875 p.) |
| Disciplina | 660.6 |
| Altri autori (Persone) | FlickingerMichael C |
| Soggetto topico | Biotechnology |
| ISBN |
9781118618981
111861898X 9781118619124 1118619129 |
| Classificazione | SCI010000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | pt. I. Introduction -- pt. II. Downstream recovery of cells and protein capture -- pt. III. Process development in downstream purification -- pt. IV. Equipment design for downstream recovery and protein purification -- pt. V. Downstream cGMP operations -- pt. VI. Biopharmaceutical facility validation -- pt. VII. FDA cGMP regulatory compliance. |
| Record Nr. | UNINA-9910968118103321 |
| Hoboken, N.J., : John Wiley & Sons Inc., 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Upstream industrial biotechnology [[electronic resource] /] / edited by Michael C. Flickinger
| Upstream industrial biotechnology [[electronic resource] /] / edited by Michael C. Flickinger |
| Pubbl/distr/stampa | Hoboken, New Jersey, : John Wiley & Sons Inc., c2013 |
| Descrizione fisica | 1 online resource (1838 p.) |
| Disciplina | 660.6 |
| Altri autori (Persone) | FlickingerMichael C |
| Soggetto topico |
Biotechnology
Biotechnology industries |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-118-61923-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
UPSTREAM INDUSTRIAL BIOTECHNOLOGY; CONTENTS; 27 Animal Cell Culture, Effects of Osmolality and Temperature; PREFACE; CONTRIBUTORS; PART I INTRODUCTION; PART II INDUSTRIAL CELL GROWTH AND GENE EXPRESSION SYSTEMS; 1 Animal Cells, Suspension Culture; 1.1 INTRODUCTION; 1.2 TYPES USED FOR LARGE-SCALE PRODUCTION IN SUSPENSION CULTURE; 1.3 SUSPENSION CULTURE REACTORS; 1.4 OPERATING MODES FOR REACTORS; 1.5 PROCESS MONITORING AND CONTROL; 1.6 CULTURE MEDIA FOR SUSPENSION CULTURE; 1.7 CONCLUSIONS; REFERENCES; 2 Baculovirus Expression Systems; 2.1 INTRODUCTION; 2.2 BACULOVIRUS STRUCTURE AND REPLICATION
2.3 PRODUCTION OF RECOMBINANT BACULOVIRUSES2.4 BACULOVIRUS TRANSFER VECTORS; 2.5 MODIFYING THE BACULOVIRUS GENOME TO IMPROVE PROTEIN PRODUCTION; 2.6 INSECT CELL CULTURE; 2.7 BACULOVIRUSES FOR GENE EXPRESSION IN MAMMALIAN CELLS; 2.8 CONCLUSION; REFERENCES; 3 Baculovirus Kinetics, Insect Culture; 3.1 HISTORY AND CHALLENGE; 3.2 BACULOVIRUS; 3.3 CELL YIELD CONCEPT; 3.4 KINETIC MODEL OF VIRAL INFECTION: SYNCHRONOUS INFECTION; 3.5 KINETIC MODEL OF VIRAL INFECTION: ASYNCHRONOUS INFECTION; REFERENCES; 4 Cell Culture, Aseptic Techniques; 4.1 INTRODUCTION; 4.2 ASEPTIC TECHNIQUE: GENERAL CONSIDERATIONS 4.3 ASEPTIC TECHNIQUE: BASIC PROCEDURES4.4 HEPA FILTRATION; 4.5 HOODS AND CABINETS EMPLOYING HEPA FILTRATION; 4.6 WORKING WITHIN UNIDIRECTIONAL AIRFLOW CABINETS AND MICROBIOLOGICAL SAFETY CABINETS; 4.7 TESTING OF CLASS I AND CLASS II MICROBIOLOGICAL SAFETY CABINETS; 4.8 CLEANROOMS FOR CELL CULTURE USE; REFERENCES; 5 Cell Cycle in Bioprocesses; 5.1 INTRODUCTION; 5.2 THE CELL CYCLE; 5.3 METHODS FOR DESCRIBING THE CELLCYCLE; 5.4 IMPORTANCE OF THE CELL CYCLE IN PROCESS BIOTECHNOLOGY; REFERENCES; 6 Cell Growth and Protein Expression Kinetics; 6.1 INTRODUCTION; 6.2 BATCH CULTURE KINETICS 6.3 CONTINUOUS CULTURE KINETICS6.4 FED-BATCH AND PERFUSION CULTURES; 6.5 CONCLUSIONS; NOMENCLATURE; REFERENCES; 7 Cell Viability Measurement; 7.1 INTRODUCTION; 7.2 PERMEABILITY ASSAYS; 7.3 FUNCTIONAL ASSAYS; 7.4 FLOW CYTOMETRY; 7.5 PHYSICAL METHODS; REFERENCES; 8 Contamination Detection in Animal Cell Culture; 8.1 INTRODUCTION; 8.2 HISTORICAL PERSPECTIVES; 8.3 REGULATORY ISSUES; 8.4 MANUFACTURING AND SAFETY TESTING STANDARDS; 8.5 EXAMPLES OF VIRAL CONTAMINANTS; 8.6 DETECTION OF VIRAL CONTAMINANTS IN CELL LINES; 8.7 TESTING RAW MATERIALS; 8.8 DETECTION OF MYCOPLASMAS; 8.9 BACTERIA AND FUNGI 8.10 OXYGEN UPTAKE RATE8.11 ENDOTOXIN DETECTION; 8.12 STATISTICAL ANALYSIS; 8.13 DETECTION OF PRIONS; 8.14 SUMMARY; REFERENCES; 9 Culture Collections and Biological Resource Centers (BRCs); 9.1 INTRODUCTION; 9.2 CULTURE COLLECTION FUNDING; 9.3 OPERATION; 9.4 QUALITY MANAGEMENT; 9.5 SERVICES; 9.6 SUMMARY; REFERENCES; FURTHER READING; 10 Culture Preservation; 10.1 INTRODUCTION; 10.2 CULTURE AND PRESERVATION OF BACTERIA; 10.3 CULTURE AND PRESERVATION OF FUNGI AND YEAST; 10.4 CULTURE AND PRESERVATION OF CELL CULTURES; REFERENCES 11 Expression and Secretion of Heterologous Proteins, Bacillus and Other Gram-Positive Bacteria |
| Record Nr. | UNINA-9910463780003321 |
| Hoboken, New Jersey, : John Wiley & Sons Inc., c2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Upstream industrial biotechnology [[electronic resource] /] / edited by Michael C. Flickinger
| Upstream industrial biotechnology [[electronic resource] /] / edited by Michael C. Flickinger |
| Pubbl/distr/stampa | Hoboken, New Jersey, : John Wiley & Sons Inc., c2013 |
| Descrizione fisica | 1 online resource (1838 p.) |
| Disciplina | 660.6 |
| Altri autori (Persone) | FlickingerMichael C |
| Soggetto topico |
Biotechnology
Biotechnology industries |
| ISBN |
1-118-61927-7
1-118-61923-4 |
| Classificazione | SCI010000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
UPSTREAM INDUSTRIAL BIOTECHNOLOGY; CONTENTS; 27 Animal Cell Culture, Effects of Osmolality and Temperature; PREFACE; CONTRIBUTORS; PART I INTRODUCTION; PART II INDUSTRIAL CELL GROWTH AND GENE EXPRESSION SYSTEMS; 1 Animal Cells, Suspension Culture; 1.1 INTRODUCTION; 1.2 TYPES USED FOR LARGE-SCALE PRODUCTION IN SUSPENSION CULTURE; 1.3 SUSPENSION CULTURE REACTORS; 1.4 OPERATING MODES FOR REACTORS; 1.5 PROCESS MONITORING AND CONTROL; 1.6 CULTURE MEDIA FOR SUSPENSION CULTURE; 1.7 CONCLUSIONS; REFERENCES; 2 Baculovirus Expression Systems; 2.1 INTRODUCTION; 2.2 BACULOVIRUS STRUCTURE AND REPLICATION
2.3 PRODUCTION OF RECOMBINANT BACULOVIRUSES2.4 BACULOVIRUS TRANSFER VECTORS; 2.5 MODIFYING THE BACULOVIRUS GENOME TO IMPROVE PROTEIN PRODUCTION; 2.6 INSECT CELL CULTURE; 2.7 BACULOVIRUSES FOR GENE EXPRESSION IN MAMMALIAN CELLS; 2.8 CONCLUSION; REFERENCES; 3 Baculovirus Kinetics, Insect Culture; 3.1 HISTORY AND CHALLENGE; 3.2 BACULOVIRUS; 3.3 CELL YIELD CONCEPT; 3.4 KINETIC MODEL OF VIRAL INFECTION: SYNCHRONOUS INFECTION; 3.5 KINETIC MODEL OF VIRAL INFECTION: ASYNCHRONOUS INFECTION; REFERENCES; 4 Cell Culture, Aseptic Techniques; 4.1 INTRODUCTION; 4.2 ASEPTIC TECHNIQUE: GENERAL CONSIDERATIONS 4.3 ASEPTIC TECHNIQUE: BASIC PROCEDURES4.4 HEPA FILTRATION; 4.5 HOODS AND CABINETS EMPLOYING HEPA FILTRATION; 4.6 WORKING WITHIN UNIDIRECTIONAL AIRFLOW CABINETS AND MICROBIOLOGICAL SAFETY CABINETS; 4.7 TESTING OF CLASS I AND CLASS II MICROBIOLOGICAL SAFETY CABINETS; 4.8 CLEANROOMS FOR CELL CULTURE USE; REFERENCES; 5 Cell Cycle in Bioprocesses; 5.1 INTRODUCTION; 5.2 THE CELL CYCLE; 5.3 METHODS FOR DESCRIBING THE CELLCYCLE; 5.4 IMPORTANCE OF THE CELL CYCLE IN PROCESS BIOTECHNOLOGY; REFERENCES; 6 Cell Growth and Protein Expression Kinetics; 6.1 INTRODUCTION; 6.2 BATCH CULTURE KINETICS 6.3 CONTINUOUS CULTURE KINETICS6.4 FED-BATCH AND PERFUSION CULTURES; 6.5 CONCLUSIONS; NOMENCLATURE; REFERENCES; 7 Cell Viability Measurement; 7.1 INTRODUCTION; 7.2 PERMEABILITY ASSAYS; 7.3 FUNCTIONAL ASSAYS; 7.4 FLOW CYTOMETRY; 7.5 PHYSICAL METHODS; REFERENCES; 8 Contamination Detection in Animal Cell Culture; 8.1 INTRODUCTION; 8.2 HISTORICAL PERSPECTIVES; 8.3 REGULATORY ISSUES; 8.4 MANUFACTURING AND SAFETY TESTING STANDARDS; 8.5 EXAMPLES OF VIRAL CONTAMINANTS; 8.6 DETECTION OF VIRAL CONTAMINANTS IN CELL LINES; 8.7 TESTING RAW MATERIALS; 8.8 DETECTION OF MYCOPLASMAS; 8.9 BACTERIA AND FUNGI 8.10 OXYGEN UPTAKE RATE8.11 ENDOTOXIN DETECTION; 8.12 STATISTICAL ANALYSIS; 8.13 DETECTION OF PRIONS; 8.14 SUMMARY; REFERENCES; 9 Culture Collections and Biological Resource Centers (BRCs); 9.1 INTRODUCTION; 9.2 CULTURE COLLECTION FUNDING; 9.3 OPERATION; 9.4 QUALITY MANAGEMENT; 9.5 SERVICES; 9.6 SUMMARY; REFERENCES; FURTHER READING; 10 Culture Preservation; 10.1 INTRODUCTION; 10.2 CULTURE AND PRESERVATION OF BACTERIA; 10.3 CULTURE AND PRESERVATION OF FUNGI AND YEAST; 10.4 CULTURE AND PRESERVATION OF CELL CULTURES; REFERENCES 11 Expression and Secretion of Heterologous Proteins, Bacillus and Other Gram-Positive Bacteria |
| Record Nr. | UNINA-9910787325803321 |
| Hoboken, New Jersey, : John Wiley & Sons Inc., c2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Upstream industrial biotechnology / / edited by Michael C. Flickinger
| Upstream industrial biotechnology / / edited by Michael C. Flickinger |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, New Jersey, : John Wiley & Sons Inc., c2013 |
| Descrizione fisica | 1 online resource (1838 p.) |
| Disciplina | 660.6 |
| Altri autori (Persone) | FlickingerMichael C |
| Soggetto topico |
Biotechnology
Biotechnology industries |
| ISBN |
9781118619278
1118619277 9781118619230 1118619234 |
| Classificazione | SCI010000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
UPSTREAM INDUSTRIAL BIOTECHNOLOGY; CONTENTS; 27 Animal Cell Culture, Effects of Osmolality and Temperature; PREFACE; CONTRIBUTORS; PART I INTRODUCTION; PART II INDUSTRIAL CELL GROWTH AND GENE EXPRESSION SYSTEMS; 1 Animal Cells, Suspension Culture; 1.1 INTRODUCTION; 1.2 TYPES USED FOR LARGE-SCALE PRODUCTION IN SUSPENSION CULTURE; 1.3 SUSPENSION CULTURE REACTORS; 1.4 OPERATING MODES FOR REACTORS; 1.5 PROCESS MONITORING AND CONTROL; 1.6 CULTURE MEDIA FOR SUSPENSION CULTURE; 1.7 CONCLUSIONS; REFERENCES; 2 Baculovirus Expression Systems; 2.1 INTRODUCTION; 2.2 BACULOVIRUS STRUCTURE AND REPLICATION
2.3 PRODUCTION OF RECOMBINANT BACULOVIRUSES2.4 BACULOVIRUS TRANSFER VECTORS; 2.5 MODIFYING THE BACULOVIRUS GENOME TO IMPROVE PROTEIN PRODUCTION; 2.6 INSECT CELL CULTURE; 2.7 BACULOVIRUSES FOR GENE EXPRESSION IN MAMMALIAN CELLS; 2.8 CONCLUSION; REFERENCES; 3 Baculovirus Kinetics, Insect Culture; 3.1 HISTORY AND CHALLENGE; 3.2 BACULOVIRUS; 3.3 CELL YIELD CONCEPT; 3.4 KINETIC MODEL OF VIRAL INFECTION: SYNCHRONOUS INFECTION; 3.5 KINETIC MODEL OF VIRAL INFECTION: ASYNCHRONOUS INFECTION; REFERENCES; 4 Cell Culture, Aseptic Techniques; 4.1 INTRODUCTION; 4.2 ASEPTIC TECHNIQUE: GENERAL CONSIDERATIONS 4.3 ASEPTIC TECHNIQUE: BASIC PROCEDURES4.4 HEPA FILTRATION; 4.5 HOODS AND CABINETS EMPLOYING HEPA FILTRATION; 4.6 WORKING WITHIN UNIDIRECTIONAL AIRFLOW CABINETS AND MICROBIOLOGICAL SAFETY CABINETS; 4.7 TESTING OF CLASS I AND CLASS II MICROBIOLOGICAL SAFETY CABINETS; 4.8 CLEANROOMS FOR CELL CULTURE USE; REFERENCES; 5 Cell Cycle in Bioprocesses; 5.1 INTRODUCTION; 5.2 THE CELL CYCLE; 5.3 METHODS FOR DESCRIBING THE CELLCYCLE; 5.4 IMPORTANCE OF THE CELL CYCLE IN PROCESS BIOTECHNOLOGY; REFERENCES; 6 Cell Growth and Protein Expression Kinetics; 6.1 INTRODUCTION; 6.2 BATCH CULTURE KINETICS 6.3 CONTINUOUS CULTURE KINETICS6.4 FED-BATCH AND PERFUSION CULTURES; 6.5 CONCLUSIONS; NOMENCLATURE; REFERENCES; 7 Cell Viability Measurement; 7.1 INTRODUCTION; 7.2 PERMEABILITY ASSAYS; 7.3 FUNCTIONAL ASSAYS; 7.4 FLOW CYTOMETRY; 7.5 PHYSICAL METHODS; REFERENCES; 8 Contamination Detection in Animal Cell Culture; 8.1 INTRODUCTION; 8.2 HISTORICAL PERSPECTIVES; 8.3 REGULATORY ISSUES; 8.4 MANUFACTURING AND SAFETY TESTING STANDARDS; 8.5 EXAMPLES OF VIRAL CONTAMINANTS; 8.6 DETECTION OF VIRAL CONTAMINANTS IN CELL LINES; 8.7 TESTING RAW MATERIALS; 8.8 DETECTION OF MYCOPLASMAS; 8.9 BACTERIA AND FUNGI 8.10 OXYGEN UPTAKE RATE8.11 ENDOTOXIN DETECTION; 8.12 STATISTICAL ANALYSIS; 8.13 DETECTION OF PRIONS; 8.14 SUMMARY; REFERENCES; 9 Culture Collections and Biological Resource Centers (BRCs); 9.1 INTRODUCTION; 9.2 CULTURE COLLECTION FUNDING; 9.3 OPERATION; 9.4 QUALITY MANAGEMENT; 9.5 SERVICES; 9.6 SUMMARY; REFERENCES; FURTHER READING; 10 Culture Preservation; 10.1 INTRODUCTION; 10.2 CULTURE AND PRESERVATION OF BACTERIA; 10.3 CULTURE AND PRESERVATION OF FUNGI AND YEAST; 10.4 CULTURE AND PRESERVATION OF CELL CULTURES; REFERENCES 11 Expression and Secretion of Heterologous Proteins, Bacillus and Other Gram-Positive Bacteria |
| Record Nr. | UNINA-9910956907403321 |
| Hoboken, New Jersey, : John Wiley & Sons Inc., c2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||