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The battle of hackham heath / / John Flanagan
| The battle of hackham heath / / John Flanagan |
| Autore | Flanagan John |
| Edizione | [Unabridged edition.] |
| Pubbl/distr/stampa | New York, : Listening Library, 2016 |
| Descrizione fisica | 1 online resource (9 audio files) : digital |
| Altri autori (Persone) |
FlanaganJohn
KeatingJohn |
| Collana | Ranger's Apprentice: The Early Years |
| Soggetto topico |
Juvenile Fiction
Fantasy Juvenile Literature |
| ISBN | 0-7352-8796-1 |
| Classificazione | JUV001000JUV037000JUV039060 |
| Formato | Audiolibri  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910136240203321 |
Flanagan John
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| New York, : Listening Library, 2016 | ||
| Audiolibri | ||
| Lo trovi qui: Univ. Federico II | ||
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XIIIth international symposium on Spermatology / / edited by Lars Bjorndahl, John Flanagan, Rebecka Holmberg
| XIIIth international symposium on Spermatology / / edited by Lars Bjorndahl, John Flanagan, Rebecka Holmberg |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (352 pages) |
| Disciplina | 571.8451 |
| Soggetto topico |
Spermatozoa
Espermatozoides |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-66292-6 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Contents -- Part I: Introduction to the Spermatology Symposium -- The 13th International Symposium on Spermatology -- Introduction to the Symposium -- A Long Series of International Symposia on Spermatology -- A Personal Dedication of the 13th Symposium -- Structure of the Symposium -- Themes -- Much Appreciated Support for the Meeting -- References -- Fifty Years of the Spermatology Symposium -- Spermatology in Sweden -- Gustaf Retzius 1842-1919 (Fig. 1) -- Retzius and Technical Excellence -- Lennart Nicander -- Leif Plöen 1941-2003 -- References -- Part II: Are Sperm at the Verge of Extinction? -- Temporal Trends in Human Sperm Counts: Findings and Implications -- References -- Is Decreasing Sperm Concentrations a Sign of a General Decay in Fertility Potential? -- Annoying Facts -- What Is Semen Quality? -- Sperm Production -- Ejaculation -- Laboratory Techniques -- Discussion and Conclusions -- References -- Environmental Toxicants and Sperm Production in Men and Animals -- Introduction -- Methods -- Study Design and Population -- Recruitment and Sampling -- Exposure Assessment -- Biochemical Analysis -- Semen Analysis -- Sperm Chromatin Structure Assay -- Animal Study -- Statistical Analysis -- Results and Discussion -- Changes in DDT/DDE Concentrations -- Hormonal Changes in Young Men -- Urine Metabolites -- SCSA -- Animal Study -- Where Do We Go from Here? -- References -- Part III: Sperm DNA: Protection and Delivery of a Complete and Undamaged Genome -- Post-testicular Sperm DNA Oxidation: What to Be Afraid of? -- Sperm as a Possible Source of Transgenerational Epimutations and Genetic Instability -- Complex Population of Chromatin-Associated Proteins Identified in Mature Sperm of the European Sea Bass (Dicentrarchus labrax) Through High-Throughput Proteomic Analysis -- Reference.
Does Cinnamtannin B-1 Protect or Destabilize Sperm DNA? Contradictory Results of SCSA® and TUNEL -- Peripubertal Serum Dioxin Concentrations and Sperm Methylome of Young Russian Adults -- Sperm DNA Fragmentation in Human Split Ejaculates -- Reference -- Part IV: Sperm Competition, Evolution and Sperm-Egg Interaction -- The Sexual Cascade: Evolutionary Dynamics of Sperm Competition -- Genotype-Phenotype Associations in Relation to Evolution of Sperm Form and Function -- From Mouse to Human: New Aspects of Sperm Transport and Fertilization Using Cutting-Edge Technologies -- First Snapshot of How Sperm Binds the Egg at the Molecular Level -- References -- The Typical and Atypical Centrioles and Their Potential Roles in the Sperm and Embryo -- Introduction -- General Overview: Typical Centriole Structure, Composition, Function, and Formation -- Typical Centrioles Are Cylindrical Cytoplasmic Structures Made of Nine Triplet Microtubules -- Typical Centrioles Often Have Associated Substructures that Correspond to the Centriole's Maturity -- A Typical Centriole Forms the Centrosome or the Cilium/Flagellum -- Centriole Maturation and Duplication Regulates Centriole Number and Structure -- Insect's Sperm and Zygote Have a Typical Centriole and an Atypical Centriole -- Insect Sperm Often Has Two Atypical Centrioles -- Zygote Centrioles -- Typical and Atypical Sperm Centrioles Function in the Zygote of Non-murine Mammals -- Non-murine Mammalian Sperm Have Two Centrioles, One Typical and One Atypical in Structure -- The Discovery of the Atypical Centriole in Non-murine Mammals -- The Two Sperm Centrioles Function in the Zygote of Non-murine Mammals -- The Confusing Status of Murine Sperm Centrioles -- Mouse Sperm Centriole Degeneration Starts in the Testis and Continues in the Epididymis -- Mice Are Thought to Have No Functional Sperm Centriole. The Evolution of the Atypical Centriole -- Sperm Competition Drives Sperm Evolution, and May Have Actively Selected for Atypical Centrioles -- Atypical Sperm Centrioles May Have Passively Evolved Due to Lack of Necessity -- Sperm Centrioles Contribute to Infertility and Reduced Male Fecundity -- A Link Between Centriole Defects and Male Infertility -- A Link Between Centriole Defect and Human Embryo Development -- More Research Is Needed for Effective Treatment of Centriole-Based Infertility -- Methods of Studying Sperm Centrioles Past, Present, and Future -- Transmission Electron Microscopy (TEM) -- Western Blot -- Immunohistochemistry -- Immunofluorescence with Classic or Super-Resolution Microscopy -- Flow Cytometry -- Final Remarks -- References -- Adaptive Modifications of the Regulation of Sperm Motility in the Diversification of Reproductive Modes of Amphibians -- Part V: Genetic Aspects of Sperm Production and Performance and its Effects on the Offspring -- When Cilia Go Bad: The Complex Genetics of Ciliopathies -- Within-Ejaculate Sperm Selection and Its Implications for Assisted Reproduction Technologies -- Introduction -- The Importance of Sperm Selection -- Possible Steps of Sperm Selection in ARTs -- Possible Future Avenues -- References -- Heads and Tails: Requirements for Informative and Robust Computational Measures of Sperm Motility -- Introduction -- Preparation Matters -- Imaging Matters -- Data Analysis Matters -- Mechanics Matters -- Conclusions -- Appendix -- References -- Effect of Cryopreservation on the Genome of Sperm in Animals and Humans -- Introduction -- Results -- Main Pillars of Genetic Integrity -- DNA -- Nucleoproteins -- Protamines -- Cryo-Related Extreme Factors that May Damage the DNA-Protein Complex -- DNA Repair System -- Imprinting -- Effect of Cryopreservation on the Genome. Cryodamage of Genetic Material in Spermatozoa -- Study of the Sperm Genome at the Molecular Level -- Development of Embryos Derived from Cryopreserved Sperm -- Study of the Sperm Genome at the Chromosomal Level -- Long-Term Study of the Effect of Cryopreservation on the Sperm Genome -- Conclusion -- References -- Mutations in the CFAP-Coding Genes Lead to Male Infertility with Multiple Morphological Abnormalities of the Sperm Flagella -- The Mouse-Specific Gly-to-Cys Mutation in Mammalian Acrosin is a Cause of Impairment in Proteolytic Activity -- Chemical and Genetic Approaches to Identify Caenorhabditis elegans Spermiogenesis-Related Factors -- Part VI: CASA: Advances and Challenges -- Routine Application of CASA in Human Clinical Andrology and ART Laboratories -- Introduction -- CASA and Human Semen Analysis -- CASA and Washed Sperm Preparations -- Issues of Non-comparability of Kinematics Between CASA Systems -- Sperm Functional Assessment: The "SFA" -- Clinical Value of the SFA -- Strategies to Validate CASA Technology for Clinical Applications -- Conclusions -- References -- Processes and Data Management of Computer-Aided Sperm Analysis in Human and Animal Spermatozoa -- CASA Parameters Quantified and Pitfalls -- CASA Parameters and Sperm Subpopulations Which Needs to Be Focused on -- Most Appropriate Quantitative and Qualitative Statistical Approaches for CASA -- Conclusion -- References -- Relationship Between Flagellar Movement and Head Trajectory at Higher Frame Rates: Is This Still a Valid Approach for CASA? -- Introduction -- Microtubule Sliding Mechanism in Sperm Flagellar Motility -- Effect of Three-Dimensional Flagellar Waves on Sperm Motility -- References -- CASA: A Suitable Tool for Epidemiology and Reprotox Studies -- Introduction -- Research Applications: Epidemiological Studies. Research Applications: Reproductive Toxicology Studies -- Applications for Chemical Exposures -- Discussion -- References -- Part VII: Challenges for Sperm Function In Vitro -- Common Challenges for Sperm In Vitro: Causes and Consequences -- Sequence of Ejaculation -- Sperm Exposure to Seminal Vesicular Fluid: An Unphysiological Challenge During Sperm Preparation for ART -- Emission and Ejaculation -- The WHO Ejaculate Is an Artefact -- Sperm Chromatin and Zinc -- Incorporation of Zinc into the Chromatin -- Sperm Chromatin Zinc and Prostatic Fluid -- Sperm Chromatin Zinc and Seminal Vesicular Fluid -- Also Zinc-Rich Semen Can Cause Sperm Chromatin Zinc Deficiency In Vitro -- Zinc Bound to Seminal Vesicular HMW Proteins Varies Between Fertile and Infertile Men -- Zinc Bridges and Disulphide Bridges in the Human Sperm Chromatin: A Model -- The "Chemical" Resistance of the Mammalian Sperm Chromatin -- Delivery: Decondensation of the Chromatin -- Sperm Chromatin Stability in Liquefied Semen -- The Zinc-Deficient Spermatozoa -- DFI and Chromatin Stability -- Gaps of Knowledge -- Searching for the Zinc-Deficient Spermatozoon -- How Can this Make Sense? -- In Conclusion -- The Sperm Osmotic Roller Coaster: Another Unphysiological Challenge During Sperm Preparation for ART -- Osmolality and Consequences for Cellular Functions -- Osmolality Going up -- Osmolality: Going Steeply Down -- References -- Main Effects of In Vitro Manipulation of Human Spermatozoa -- Introduction -- In Vitro Manipulation during Sperm Selection for ARTs -- In Vitro Sperm Incubation During IVF/ICSI Procedures -- In Vitro Manipulation During Sperm Cryopreservation -- Conclusions -- References -- Effect of Melatonin on Capacitation and Ca2+ Distribution in Red Deer Spermatozoa -- References. Unraveling the Signal Transduction Pathways of Novel Mitochondrial Peroxiporins in Activated Piscine Spermatozoa. |
| Record Nr. | UNINA-9910495216203321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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