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Aquareovirus / / edited by Qin Fang
| Aquareovirus / / edited by Qin Fang |
| Pubbl/distr/stampa | Singapore : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (242 pages) |
| Disciplina | 016.33395 |
| Soggetto topico |
Fishes - Diseases
Shellfish - Diseases Malalties dels peixos Virus |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 981-16-1903-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Contents -- Contributors -- Chapter 1: Aquareovirus: An Overview -- 1.1 Introduction -- 1.2 Origin of AqRV -- 1.3 Characteristic Features of AqRV -- 1.4 Taxonomy and Classification of the Genus AqRV -- 1.5 Geographic and Seasonal Distribution -- 1.6 Host Range and Viral Proliferation -- 1.7 Antigenic and Serological Characterization of AqRV -- 1.8 Representative and Pathogenic AqRV Strains -- 1.9 Conclusions and Future Considerations -- References -- Chapter 2: Molecular Biology of Aquareoviruses -- 2.1 Introduction -- 2.2 Particle-Based Properties -- 2.2.1 Virus Proliferation and Sample Preparation -- 2.2.2 Different Particle Components Extracted from Purified Virus Preparations -- 2.2.2.1 Intact Virions and Empty Particles -- 2.2.2.2 SVP and Virus Core -- 2.2.3 The Virus-Antibody Immunocompound of GCRV -- 2.2.4 Recombinant GCRV Particles -- 2.2.5 Surface Labeling of AqRV Particles -- 2.2.6 Infectivity Assays of Purified or Modified Virions and SVPs -- 2.3 AqRV Structural Protein Profile -- 2.3.1 Identification of AqRV Particle Proteins -- 2.3.2 Various Particle Forms and Related Protein Profiles -- 2.4 In Vitro Endogenous Transcription Assays of GCRV Particles -- 2.4.1 GCRV Nucleic Acid Release -- 2.4.2 GCRV Reaction Core -- 2.4.3 In Vitro Transcription Assays -- 2.5 The AqRV Genome -- 2.5.1 Nomenclature and Electrophoresis Profile of the AqRV dsRNA Genome -- 2.5.2 Genome Sequence-Based Features of AqRVs -- 2.5.3 Terminal Non-coding Regions -- 2.5.4 Protein-Coding Assignments and Nomenclature -- 2.5.4.1 SBRV Gene-Protein-Coding Assignment -- 2.5.4.2 GCRV Gene-Protein-Coding Assignment -- 2.5.5 In Vitro and In Vivo Protein Expression Analyses -- 2.6 AqRV Morphogenesis -- 2.6.1 TEM Analysis of VIB Formation in Infected Cells -- 2.6.2 NS80: A Scaffold of VIBs -- 2.6.3 Interaction of NS80 with Viral Proteins.
2.6.4 Role of NS38 in GCRV Morphogenesis -- 2.7 GCRV S7 Genome Segment-Encoded FAST Protein and Associated Syncytium Formation -- 2.7.1 Detection of FAST Protein -- 2.7.2 Sequence-Based Features of FAST Protein -- 2.7.3 NS16 and NS22: The AqRV FAST Proteins -- 2.7.4 NS12: A Novel Membrane-Associated Protein -- 2.7.5 Role of NS31 in Virus Replication -- 2.7.6 Possible Function of GCRV NS26 in Syncytia Formation -- 2.8 MRV σ1-like Cell Attachment Protein of GCRV-II Species -- 2.9 Conclusions and Future Considerations -- References -- Chapter 3: The Aquareovirus Particle Structure and Protein Functions -- 3.1 Introduction -- 3.2 The Aquareovirus Particle and Its Structural Protein Localization -- 3.2.1 Similarities and Differences between the Aquareovirus, Orthoreovirus, and Other Viruses in the Family Reoviridae -- 3.2.2 Comparison of Structural Proteins in the Aquareoviruses and Orthoreoviruses -- 3.3 Cryo-EM Analysis of the Aquareovirus/GCRV Virions -- 3.3.1 Electron Cryomicrograph Records of the Purified GCRV Cores and Virions -- 3.3.2 Overall Three-dimensional Structures of the Aquareovirus Virion -- 3.3.3 Features of the Aquareovirus Outer Capsid -- 3.3.4 Specialized Regions Around the Five-Fold Axes -- 3.3.5 Differences in the Features of the Aquareovirus and MRV Core Structures -- 3.3.6 Centrally Condensed dsRNA Genome -- 3.4 Protein Localization and Functional Analysis -- 3.4.1 The Inner Shell Proteins (ISPs) -- 3.4.1.1 Core Frame Protein VP3 -- 3.4.1.2 Core Clamping Protein VP6 -- 3.4.1.3 Turret Protein VP1 -- 3.4.1.4 RdRP Protein VP2 -- 3.4.1.5 RdRP Co-factor Protein VP4 -- 3.4.1.6 Interactions of the VP2-VP4 Complex with the N-termini of VP3A and VP3B -- 3.4.2 The Outer Capsid Proteins -- 3.4.2.1 The Membrane Penetration Protein VP5 -- 3.4.2.2 Interaction of VP5 with Other Proteins -- 3.4.2.3 Surface Protection Protein VP7. 3.4.2.4 Biological Functions of VP5 and VP7 -- 3.5 Conclusions and Future Considerations -- References -- Chapter 4: The Aquareovirus Infection and Replication -- 4.1 Introduction -- 4.2 Tissue Tropism -- 4.3 Cell Attachment -- 4.4 Membrane Penetration -- 4.5 Endogenous Transcription -- 4.6 Virus-Producing Cytoplasmic Factories -- 4.7 Nascent Virus Release -- 4.8 Conclusions and Future Considerations -- References -- Chapter 5: Epidemiology of the Grass Carp Reovirus -- 5.1 Introduction -- 5.2 Geographical Distribution -- 5.3 Host Range and Age -- 5.4 Clinical Features and Epidemic Potential of GCHD -- 5.5 Virus Transmission -- 5.6 Molecular Epidemiology -- 5.7 In Vitro GCRV Infection -- 5.8 Conclusions and Future Considerations -- References -- Chapter 6: Clinical Features and Diagnosis of Aquareovirus Infection -- 6.1 Introduction -- 6.2 Clinical Features and Pathology -- 6.3 Traditional Detection Methods -- 6.3.1 Viral Culture Method -- 6.3.2 EM -- 6.3.3 Genomic Electropherotype Analysis -- 6.4 Nucleic Acid-Based Methods -- 6.4.1 PCR -- 6.4.1.1 Conventional RT-PCR -- 6.4.1.2 Nested RT-PCR -- 6.4.1.3 Multiplex RT-PCR -- 6.4.2 Real-Time PCR -- 6.4.3 LAMP -- 6.4.4 Other Nucleic Acid Amplification Technologies -- 6.4.5 Nucleic Acid Hybridization -- 6.5 Immunological Methods -- 6.6 Conclusions and Future Considerations -- References -- Chapter 7: Prevention and Control of Grass Carp Hemorrhagic Disease -- 7.1 Introduction -- 7.2 Inactivated Vaccines -- 7.2.1 Inactivated GCRV Tissue Culture Vaccine -- 7.2.2 Inactivated GCRV Cell Culture Vaccine -- 7.3 Live-Attenuated Vaccines -- 7.4 Recombinant Subunit Vaccines -- 7.5 DNA Vaccines -- 7.6 Conclusions and Future Considerations -- References -- Chapter 8: Medical Treatment of Grass Carp Hemorrhagic Disease -- 8.1 Introduction -- 8.2 Effects of Natural Compounds Against the GCRV. 8.2.1 (-)-Epigallocatechin-3-Gallate (EGCG) -- 8.2.2 Magnolol and Honokiol -- 8.2.3 Quercetin -- 8.3 Effect of Chemical Inhibitors Against the GCRV -- 8.3.1 Heparin and Chondroitin Sulfate -- 8.3.2 Moroxydine Hydrochloride (Mor) -- 8.3.3 Ribavirin (Rib) -- 8.4 Effects of Endocytosis Inhibitors Against the GCRV -- 8.5 Conclusions and Future Considerations -- References -- Chapter 9: Anti-Aquareovirus Immunity -- 9.1 Introduction -- 9.2 Innate Immunity -- 9.2.1 High-Mobility Group Box Proteins -- 9.2.2 TLR Signaling Pathways -- 9.2.2.1 TLRs -- 9.2.2.2 TLR Adaptor Molecules -- 9.2.2.3 MyD88-Dependent TLR Signaling Pathway -- 9.2.2.4 MyD88-Independent TLR Signaling Pathway -- 9.2.2.5 Transcription Factors -- 9.2.3 RLR Signaling Pathways -- 9.2.3.1 Expression Profiles of RLRs In Vivo and In Vitro -- 9.2.3.2 Antiviral Functions of RLRs -- 9.2.3.3 Signaling Crosstalk Between RLRs and Other Pathways -- 9.2.4 Other Antiviral Signaling Pathways -- 9.2.4.1 NLRs -- 9.2.4.2 Scavenger Receptor, ADAR, Protein Kinase R, Z-DNA Binding Protein Kinase, and RNA Interference -- 9.3 Adaptive Immunity -- 9.4 Conclusions and Future Considerations -- References. |
| Record Nr. | UNINA-9910492145003321 |
| Singapore : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Progressive Collapse Resilience of Concrete Structures: Mechanisms, Simulations and Experiments / / by Kai Qian, Qin Fang
| Progressive Collapse Resilience of Concrete Structures: Mechanisms, Simulations and Experiments / / by Kai Qian, Qin Fang |
| Autore | Qian Kai |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (286 pages) |
| Disciplina | 624.151 |
| Altri autori (Persone) | FangQin |
| Soggetto topico |
Geotechnical engineering
Buildings—Design and construction Engineering geology Geotechnical Engineering and Applied Earth Sciences Building Construction and Design Geoengineering |
| ISBN | 981-9907-72-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1. Introduction -- Chapter 2. Mechanisms of progressive collapse of concrete structures -- Chapter 3. Dynamic increase factor (DIF) of concrete structures -- Chapter 4. Spatial and slab effects on concrete structures -- Chapter 5. Mechanisms of progressive collapse of flat slab structures -- Chapter 6. Performance of infilled frames during progressive collapse -- Chapter 7. Vulnerability and robustness of RC frames to resist progressive collapse. |
| Record Nr. | UNINA-9910734870103321 |
Qian Kai
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| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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