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Biological Engagement Programs: Reducing Threats and Strengthening Global Health Security Through Scientific Collaboration
Biological Engagement Programs: Reducing Threats and Strengthening Global Health Security Through Scientific Collaboration
Autore Wolfe Nathan
Pubbl/distr/stampa Frontiers Media SA, 2017
Descrizione fisica 1 electronic resource (199 p.)
Collana Frontiers Research Topics
Soggetto non controllato Infectious disease
biosecurity
Cooperative Biological Engagement
select agents
biosafety
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti Biological Engagement Programs
Record Nr. UNINA-9910261143703321
Wolfe Nathan  
Frontiers Media SA, 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Plague
Plague
Autore Atshabar Bakyt B
Edizione [1st ed.]
Pubbl/distr/stampa Cham : , : Springer International Publishing AG, , 2024
Descrizione fisica 1 online resource (183 pages)
Altri autori (Persone) StensethNils Chr
FairJeanne M
Collana Birkhäuser Advances in Infectious Diseases Series
ISBN 3-031-58831-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Foreword -- Preface -- Acknowledgments -- Contents -- About the Editors and Contributors -- About the Editors -- Contributors -- Part I: Variability and Selection of Yersinia pestis in the Natural Plague Focus -- Chapter 1: Introduction -- Definitions -- Chapter 2: Ecological Bases of Yersinia pestis Variability in the Nature -- 2.1 Population Distribution of Yersinia pestis in Natural Foci -- 2.2 Virulence of Yersinia pestis Populations -- 2.2.1 Properties of Arginine-Dependent Virulent Population of Yersinia pestis in the Ural-Oiyl Steppe Plague Focus -- 2.3 Auxotrophicity of Yersinia pestis. Search for Selection Factors of Yersinia pestis Populations in the Nature -- 2.3.1 The Effect of the Amino Acid Amount in a Solid Medium on the Yersinia pestis Growth -- 2.4 The Level of Free Amino Acids in the Rodent Blood Serum from Plague Foci -- 2.5 Some Features of Yersinia pestis Populations from Natural Plague Foci -- 2.5.1 Atypical Yersinia pestis Strains in Natural Plague Foci -- 2.6 Features of Plague Pathogenesis -- 2.7 The Role of Oxygen-Dependent Metabolism of Phagocytes in Plague Resistance -- References -- Definitions -- Untitled -- Chapter 3: Mutational Variability of Yersinia pestis Under the Action of Phagocytising Cells of Rodents -- 3.1 The Mechanism of Phagocytes' Mutagenic Activity -- 3.2 The Action of Active Oxygen Species -- 3.3 Modelling of the "Polymorphonuclear Leukocytes-Yersinia pestis" System In Vitro -- 3.3.1 The In Vitro Study of Mutagenesis -- 3.4 Modelling of the "Intraperitoneal Phagocyte-Yersinia pestis" System In Vivo -- 3.4.1 The In Vivo Study of Mutagenesis -- 3.5 Properties of Yersinia pestis Mutants -- 3.5.1 Properties of Yersinia pestis Mutants Obtained in In Vitro and In Vivo Experiments -- References -- Definitions.
Chapter 4: Environmental Aspects of Yersinia pestis Virulence and Selection in the Natural Plague Focus -- 4.1 Pathogenicity and Virulence of Yersinia pestis -- 4.2 On Resistance to Plague -- 4.3 Natural Selection in the Natural Plague Focus -- 4.3.1 Selection of the Yersinia pestis Population in the Natural Plague Focus -- References -- Definitions -- Chapter 5: The Main Carrier's Function in the Natural Plague Focus -- 5.1 On Host Specificity of the Natural Plague Focus -- 5.2 On the Hypothesis of Yersinia pestis Emergence from Saprophytes -- 5.2.1 Is That Possible? -- 5.3 On Taxonomy of Yersinia pestis -- 5.4 The Natural Plague Focus as an Ecological System -- 5.4.1 Principal Conditions for the Existence of a Natural Plague Focus -- References -- Definitions -- Part II: History and Ecology of Plague -- Chapter 6: The Ecology of Plague -- 6.1 Introduction -- 6.2 The Plague Bacterium in Reservoirs, Outbreak in Nature, and in Human Settlements -- 6.3 The Geographic Distribution of Plague Today -- 6.4 Non-human Host Species and Vectors -- 6.5 The Enzootic Stage: Plague Reservoirs -- 6.6 The Epizootic Stage: Plague Outbreak in Natural Rodent Populations -- 6.7 The Zoonotic Stage: The Spillover to Domestic Animals and Humans -- 6.8 Practical Insights of the Existence of the Outbreak Threshold and the Spill-Over Threshold -- 6.9 Ecologically Determined Evolutionarily Selective Pressure -- 6.10 Transmission of Plague Bacteria Among Humans -- 6.11 Ecological Questions Which Need Further Work -- References -- Chapter 7: The Evolutionary History of Yersinia pestis -- 7.1 Late Neolithic and Bronze Age: preLNBA- and LNBA-, Limited Flea-Adapted Lineages -- 7.2 The Bronze Age Expansion (c.2400-1800 BCE): Emerging of LNBA+, Flea-Adapted Lineages -- 7.3 From the Iron Age to the Later Middle Ages: 0.ANT Lineages.
7.4 The First Plague Pandemic (c.541-c.770): 0.ANT4 Lineage -- 7.5 The Beginnings of the Second Plague Pandemic (c.1338-41): The Great Polytomy (the 'Big Bang') -- 7.6 The Great Polytomy to Present: Branches 1-4 -- 7.6.1 Focalisation of Branch 1 in Central Europe, c. 1349-56 -- 7.6.2 Branch 1A Perseverance and Splits, c.1362-1772 -- 7.6.3 Branch 1B: Pestis secunda to Present -- 7.6.4 Branch 2 -- 7.6.5 Branches 3-4 -- 7.7 Yersinia pestis Evolutionary Questions Which Need Further Work -- References -- Index.
Record Nr. UNINA-9910878992403321
Atshabar Bakyt B  
Cham : , : Springer International Publishing AG, , 2024
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui