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Drug delivery strategies for poorly water-soluble drugs [[electronic resource] /] / edited by Dennis Douroumis and Alfred Fahr
| Drug delivery strategies for poorly water-soluble drugs [[electronic resource] /] / edited by Dennis Douroumis and Alfred Fahr |
| Pubbl/distr/stampa | Chichester, West Sussex, : John Wiley & Sons, 2012 |
| Descrizione fisica | 1 online resource (644 p.) |
| Disciplina | 615.1 |
| Altri autori (Persone) |
DouroumisDennis
FahrAlfred |
| Collana | Advances in pharmaceutical technology |
| Soggetto topico |
Drug delivery systems
Pharmaceutical chemistry Drug carriers (Pharmacy) Solubility |
| ISBN |
1-118-44472-8
1-299-25270-2 1-118-44477-9 1-118-44467-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Self-assembled delivery vehicles for poorly water-soluble drugs : basic theoretical considerations and modeling concepts / Silvio May and Alfred Fahr -- Liposome as intravenous solubilizers for poorly water soluble drugs / Peter van Hoogevest, Mathew Leigh and Alfred Fahr -- Drug solubilization and stabilization of cyclodextrin drug carriers / Thorsteinn Loftsson and Marcus Eli Brewster -- Solid lipid nanoparticles for drug delivery / Sonja Joseph and Heike Bunjes -- Polymeric drug delivery systems for encapsulating hydrophobic drugs / Naveed Ahmed, C.E. Mora-Heurtas, Chiraz Jaafar-Maalej, Hatem Fessi and Abdelhamid Elaissari -- Polymeric drug delivery systems for encapsulating hydrophobic drugs / Dagmar Fischer -- Development of self-emulsifying drug delivery systems (SEDDS) for oral ioavailability enhancement of poorly soluble drugs / Dimitrios G. Fatouros and Anette Müllertz -- Novel top-down technologies : effective production of ultra-fine drug nanocrystals / Cornelia.M. Keck, S. Kobierski, R. Mauludin and Rainer H. Müller -- Nanosuspensions with enhanced drug dissolution rates of poorly water-soluble drugs / Dennis Douroumis -- Microemulsions for drug solubilization and delivery / X.Q. Wang and Qiang Zhang -- Enhancing drug solubility and bioavailability using hot melt extruded solid dispersions / Shu Li, David S. Jones and Gavin P. Andrews -- Penetration enhancers, solvents and the skin / Jonathan Hadgraft and Majella E. Lane -- Dendrimers for enhanced drug solubilization / Narendra K. Jain and Rakesh K. Tekade -- Polymeric micelles for the delivery of poorly soluble drugs / Swati Biswas, Onkar S.Vaze, Sara Movassaghian and Vladimir P. Torchilin -- Nanostructured silicon-based materials as a drug delivery system for water insoluble drugs / Vesa-Pekka Lehto, Jarno Salonen, Helder Santos and Joakim Riikonen -- Micro- and nanosizing of poorly soluble drugs by grinding techniques / Stefan Scheler -- Enhanced solubility of poorly soluble drugs via spray drying / Cordin Arpagaus, David Rütti and Marco Meuri. |
| Record Nr. | UNINA-9910141512303321 |
| Chichester, West Sussex, : John Wiley & Sons, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Drug delivery strategies for poorly water-soluble drugs / / edited by Dennis Douroumis and Alfred Fahr
| Drug delivery strategies for poorly water-soluble drugs / / edited by Dennis Douroumis and Alfred Fahr |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Chichester, West Sussex, : John Wiley & Sons, 2012 |
| Descrizione fisica | 1 online resource (644 p.) |
| Disciplina | 615.1 |
| Altri autori (Persone) |
DouroumisDennis
FahrAlfred |
| Collana | Advances in pharmaceutical technology |
| Soggetto topico |
Drug delivery systems
Pharmaceutical chemistry Drug carriers (Pharmacy) Solubility |
| ISBN |
1-118-44472-8
1-299-25270-2 1-118-44477-9 1-118-44467-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Self-assembled delivery vehicles for poorly water-soluble drugs : basic theoretical considerations and modeling concepts / Silvio May and Alfred Fahr -- Liposome as intravenous solubilizers for poorly water soluble drugs / Peter van Hoogevest, Mathew Leigh and Alfred Fahr -- Drug solubilization and stabilization of cyclodextrin drug carriers / Thorsteinn Loftsson and Marcus Eli Brewster -- Solid lipid nanoparticles for drug delivery / Sonja Joseph and Heike Bunjes -- Polymeric drug delivery systems for encapsulating hydrophobic drugs / Naveed Ahmed, C.E. Mora-Heurtas, Chiraz Jaafar-Maalej, Hatem Fessi and Abdelhamid Elaissari -- Polymeric drug delivery systems for encapsulating hydrophobic drugs / Dagmar Fischer -- Development of self-emulsifying drug delivery systems (SEDDS) for oral ioavailability enhancement of poorly soluble drugs / Dimitrios G. Fatouros and Anette Müllertz -- Novel top-down technologies : effective production of ultra-fine drug nanocrystals / Cornelia.M. Keck, S. Kobierski, R. Mauludin and Rainer H. Müller -- Nanosuspensions with enhanced drug dissolution rates of poorly water-soluble drugs / Dennis Douroumis -- Microemulsions for drug solubilization and delivery / X.Q. Wang and Qiang Zhang -- Enhancing drug solubility and bioavailability using hot melt extruded solid dispersions / Shu Li, David S. Jones and Gavin P. Andrews -- Penetration enhancers, solvents and the skin / Jonathan Hadgraft and Majella E. Lane -- Dendrimers for enhanced drug solubilization / Narendra K. Jain and Rakesh K. Tekade -- Polymeric micelles for the delivery of poorly soluble drugs / Swati Biswas, Onkar S.Vaze, Sara Movassaghian and Vladimir P. Torchilin -- Nanostructured silicon-based materials as a drug delivery system for water insoluble drugs / Vesa-Pekka Lehto, Jarno Salonen, Helder Santos and Joakim Riikonen -- Micro- and nanosizing of poorly soluble drugs by grinding techniques / Stefan Scheler -- Enhanced solubility of poorly soluble drugs via spray drying / Cordin Arpagaus, David Rütti and Marco Meuri. |
| Record Nr. | UNINA-9910817900703321 |
| Chichester, West Sussex, : John Wiley & Sons, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Nanotechnology in Therapeutics : Basics and Trends
| Nanotechnology in Therapeutics : Basics and Trends |
| Autore | Demetzos Costas |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Newark : , : John Wiley & Sons, Incorporated, , 2024 |
| Descrizione fisica | 1 online resource (303 pages) |
| Disciplina | 615/.6 |
| Altri autori (Persone) |
DouroumisDennis
SnowdenMartin J FahrAlfred SiepmannJuergen TorchilinVladimir P |
| Collana | Advances in Pharmaceutical Technology Series |
| Soggetto topico |
Nanomedicine
Nanoparticles |
| ISBN |
1-394-27408-4
1-394-27406-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Series Page -- Title Page -- Copyright Page -- Dedication Page -- Contents -- About the Author -- Foreword -- Advances in Pharmaceutical Technology: Series Preface -- Preface -- Acknowledgments -- List of Abbreviations -- List of Figures -- List of Tables -- Part A Nanotechnology: Introduction and Brief Historical Overview -- Chapter 1 Introduction and Applications of Nanotechnology -- 1.1 Nanotechnology: Introduction and Brief Historical Overview -- 1.2 An Overview of Nanomedicines -- 1.3 Nanomedicine -- 1.4 The Strategic Research and Innovation Agenda for anomedicine (SRIA) 2016-2030 (www.etp-nanomedicine.eu) -- References -- Chapter 2 Biophysics, Thermodynamics, and Stability of Colloidal Dispersion Nanosystems -- 2.1 The Eukaryotic Cell Membranes -- 2.1.1 Structure and Function of Cell Membranes -- 2.1.2 Thermodynamic Properties of the Lipid Bilayers of Cell Membranes -- 2.2 Liquid Crystals (LCs) -- 2.2.1 Thermotropic and Lyotropic Liquid Crystals -- 2.3 Liquid Crystals in Biological Systems -- 2.4 The Role of Lipidic Domains in Cell Membranes -- 2.4.1 Lipid Conformational and Motional Properties -- 2.5 Dispersion Nanosystems -- 2.6 Stability of Nanocolloidal Dispersion Systems -- 2.6.1 Fundamentals of DLVO Theory -- 2.7 The DLVO Theory -- 2.7.1 Historical Background in Brief -- 2.7.2 Extension of the Classic DLVO Theory -- 2.7.3 Classification of Hydration Forces During the Interaction of Nanoparticles of a Colloidal Dispersion System -- 2.7.4 Entropic Effect -- 2.7.5 Osmotic Effect -- 2.7.6 Enthalpic Stabilization -- 2.8 Introduction to Applied Thermodynamics and Biothermodynamics -- 2.8.1 Introduction to Thermodynamics -- 2.8.2 Small System Thermodynamics -- 2.8.3 Comparison of Thermal Analysis with Other Analytical Techniques -- 2.8.4 Classification of Thermal Analysis Techniques.
2.8.5 Differential Scanning Calorimetry: Basic Principles -- 2.8.6 Polymorphism - Lyotropism -- 2.8.7 Differential Scanning Calorimetry (DSC) Types -- 2.9 Light Scattering Techniques -- 2.9.1 Photon Correlation Spectroscopy (PCS) -- 2.10 Microscopy -- 2.10.1 Optical Microscopy -- 2.10.2 Electron Microscopy -- 2.10.3 Scanning Probe Microscopy -- References -- Part B Lipid and Polymeric Nanostructures in Medicine -- Chapter 3 Liposomes: An Overview -- 3.1 Introduction and Historical Issues of Liposomal Technology -- 3.2 Types of Liposomes -- 3.3 Entrapment of Bioactive Molecules in Multilamellar Lipid Vesicles and Liposomes -- 3.4 Advantages of Liposomes -- 3.5 Liposomes as Model of the Cell Membrane and Properties of Their Liquid Crystalline State of Matter -- 3.6 Liposome Physicochemical Characterization and Their Physical Stability -- 3.6.1 Summary of Liposome Preparation Methods -- 3.7 Liposomes as Analytical Tool -- 3.7.1 Biosensors Based on Liposome Technology -- 3.7.2 Future Perspectives in Lipidic Drug Delivery Nanosystems -- References -- Chapter 4 Lipidic and Polymeric Nanomedicines in Clinical Applications -- 4.1 Liposomal Nanomedicines -- 4.1.1 Anticancer Liposomal Medicines -- 4.1.2 Antifungal Liposomal and Lipidic-based Nanomedicines. Case Study of Liposomal and Lipidic-based Amphotericin B -- 4.1.3 Lipid Nanoparticles -- 4.2 Advanced Liposomal Nanomedicines -- 4.2.1 Stimuli-responsive Liposomal Nanosystems -- 4.2.2 Immunoliposomes -- 4.2.3 Mitochondria as Target Domain -- 4.3 Polymers -- 4.3.1 Polyelectrolytes -- 4.4 Polymersomes -- 4.4.1 Polymersome Size and Size Distribution Evaluation -- 4.4.2 Polymersome Properties and Applications -- 4.4.3 Polymersome Surface Chemistry -- 4.4.4 Polymerosome Applications -- 4.5 Biodegradable Polymeric Nanoparticles -- 4.6 Polymeric Micelles -- 4.7 Dendrimers -- 4.7.1 Dendrimer Use in Biomedicine. 4.7.2 Dendrimer Applications -- 4.7.3 Dendrimer Application in Diagnostics with Magnetic Resonance Imaging Technique -- References -- Chapter 5 Applied Nanotechnology -- 5.1 Nanotechnology in Therapeutics -- 5.2 Nanotechnology and Cancer -- 5.3 Nanooncology and Gene Transfer -- 5.4 Nanobiotechnology -- 5.5 Nanogenomics and Nanoproteomics -- 5.6 Delivery Nanosystems for Therapeutic Biological Products -- 5.7 New Therapies Based on Nanotechnology -- 5.8 Theranostics -- 5.8.1 Theranostics: Applications in the Treatment, Diagnosis of Diseases, and Tissue Monitoring -- References -- Chapter 6 Nanotechnology in Vaccines -- 6.1 Introduction to Vaccines -- 6.2 Development of Novel Nanovaccines -- 6.3 Liposomes, Lipid Nanoparticles, and Nonviral Lipid Nanoparticles (Virosomes) -- 6.4 Vaccines Against SARS‐CoV‐2 Virus -- 6.4.1 Stability of Nanovaccines as Nanocolloids -- 6.5 Future Perspectives and the Concept of the "Thermodynamic Epitope" -- 6.6 LNPs‐based Nanovaccines in Clinical Applications -- 6.6.1 Comirnaty® -- 6.6.2 Spikevax -- References -- Part C Nanotechnology and Nanomedicine: The Regulatory Landscape -- Chapter 7 New Health Technologies and Regulatory Approaches -- 7.1 New Health Technologies and the Regulatory Landscape for the Approval Process -- 7.2 Nanoinformatics -- 7.2.1 Artificial Intelligence (AI) -- 7.3 Complex Systems, Complexity, and Artificial Bionanosystems -- 7.4 Chaos and Nonlinear Dynamics in Nanocolloids -- 7.4.1 Chaotic Dynamic Systems -- 7.4.2 Lyapunov Approximation -- 7.4.3 Linking Lyapunov Exponents to Information -- 7.5 Nanocolloids. Complexity, Chaos, and Stability -- 7.6 Regulatory Agencies -- 7.6.1 Medicine Approval Processes -- 7.7 Advanced Therapy Medicinal Products (ATMPs) -- 7.8 Approval Process for Advanced Therapy Medicinal Products. 7.9 The Regulatory Framework for the Nanobiotechnological Products in the United States and the Role of the FDA -- 7.10 Regulatory Issues for Biotechnological Medicines. The Role of the EMA -- 7.11 Committee for Advanced Therapies (CAT) -- 7.12 Nanosimilars -- 7.13 Generics and Biosimilar Therapeutic Products -- References -- Index -- EULA. |
| Record Nr. | UNINA-9910878995403321 |
Demetzos Costas
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| Newark : , : John Wiley & Sons, Incorporated, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||