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Alternatives for Dermal Toxicity Testing / / edited by Chantra Eskes, Erwin van Vliet, Howard I. Maibach
| Alternatives for Dermal Toxicity Testing / / edited by Chantra Eskes, Erwin van Vliet, Howard I. Maibach |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (XX, 592 p. 92 illus., 61 illus. in color.) |
| Disciplina | 616.5 |
| Soggetto topico |
Dermatology
Pharmacology Animal models in research Pharmacology/Toxicology Animal Models |
| ISBN | 3-319-50353-7 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Concepts -- Skin irritation -- Skin corrosion -- Skin sensitization -- UV-induced effects (phototoxicity & photoallergy) -- Skin genotoxicity -- Other exploratory areas of relevance. |
| Record Nr. | UNINA-9910254487003321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Validation of Alternative Methods for Toxicity Testing / / edited by Chantra Eskes, Maurice Whelan
| Validation of Alternative Methods for Toxicity Testing / / edited by Chantra Eskes, Maurice Whelan |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (XX, 407 p. 44 illus., 40 illus. in color.) |
| Disciplina | 615.704028 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Pharmaceutical technology
Molecular biology Pharmaceutical Sciences/Technology Molecular Medicine |
| ISBN | 3-319-33826-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Validation in support of internationally harmonised OECD Test Guidelines for assessing the safety of chemicals -- Regulatory acceptance of alternative methods in the development and approval of pharmaceuticals -- Validation of alternative in vitro methods to animal testing: concepts, challenges, processes and tools -- Practical aspects of designing and conducting validation studies involving multi-study trials -- Validation of computational methods -- Implementation of New Test Methods into Practical Testing -- Pathway Based Toxicology and Fit-for-Purpose Assays -- Evidence-based toxicology -- Validation of transcriptomics-based in vitro methods -- Ensuring the quality of stem cell-derived in vitro models for toxicity testing -- Validation of bioreactor and human-on-a-chip devices for chemical safety assessment -- Integrated approaches to testing and assessment -- International harmonization and cooperation in the validation of alternative methods -- Evolving the principles and practice of validation for new alternative approaches to toxicity testing. . |
| Record Nr. | UNINA-9910253895003321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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