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Physical principles in sensing and signaling [[electronic resource] ] : with an introduction to modeling in biology / / Robert G. Endres
| Physical principles in sensing and signaling [[electronic resource] ] : with an introduction to modeling in biology / / Robert G. Endres |
| Autore | Endres Robert G |
| Pubbl/distr/stampa | Oxford, : Oxford University Press, 2013 |
| Descrizione fisica | 1 online resource (158 p.) |
| Disciplina |
571.43
571.634 |
| Soggetto topico |
Biology - Simulation methods
Biology - Mathematical models |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-283-85621-2
0-19-165428-0 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Contents; 1 Introduction; Chapter summary; Further reading; 2 Chemotaxis in bacterium Escherichia coli; 2.1 Chemical gradient sensing; 2.2 "Nose and brain": the receptor cluster; 2.3 E. coli chemotaxis pathway; 2.4 Experimental approaches; 2.5 Time-course data and dose-response curves; Chapter summary; Further reading; 3 Physical concepts; 3.1 Diffusion; 3.2 Boltzmann distribution; 3.3 Ligand-receptor binding; 3.4 Fluctuation-dissipation theorem; Chapter summary; Further reading; 4 Mathematical tools; 4.1 Ordinary differential equations; 4.2 Kinetic laws; 4.3 Master equation
4.4 Poisson distribution4.5 Waiting-time distribution; 4.6 Langevin small-noise approximation; 4.7 Information theory; Chapter summary; Further reading; 5 Signal amplification and integration; 5.1 Cooperativity by allostery; 5.2 Emergence of allostery from microscopic details; 5.3 Two-state equilibrium receptor model; 5.4 Monod-Wyman-Changeux model for receptor signaling; 5.5 Alternative Ising model for receptor cluster; Chapter summary; Further reading; 6 Robust precise adaptation; 6.1 Energy-landscape picture of adaptation; 6.2 Dynamics of adaptation; 6.3 Chemotactic response function 6.4 Integral-feedback control6.5 Assistance neighborhoods; Chapter summary; Further reading; 7 Polar receptor localization and clustering; 7.1 Trimer of dimers; 7.2 Elastic cluster-membrane model; 7.3 Polar receptor clustering; Chapter summary; Further reading; 8 Accuracy of sensing; 8.1 Perfectly absorbing sphere; 8.2 Perfectly monitoring sphere; 8.3 Sensing with cell-surface receptors; Chapter summary; Further reading; 9 Motor impulse response; 9.1 Impulse response; 9.2 Time and frequency domains; 9.3 Minimal pathway model; 9.4 Linear response approximation; 9.5 Noise power spectra Chapter summaryFurther reading; 10 Optimization of pathway; 10.1 Optimal receptor-complex size; 10.2 Optimal adaptation dynamics; Chapter summary; Further reading; 11 "Seeing like a bacterium"; 11.1 Typical chemical gradients; 11.2 Weber's law; 11.3 Perception; 11.4 Fold-change detection; 11.5 Matching relations; 11.6 Predicting typical stimuli; Chapter summary; Further reading; 12 Beyond E. coli chemotaxis; Chapter summary; Further reading; Appendix More techniques; A.1 Derivation of the fluctuation-dissipation theorem; A.2 Variational principles and the Euler-Lagrange equation A.3 Gillespie simulationsA.4 Fokker-Planck approximation; A.5 Derivation of the Langevin noise; A.6 Time versus frequency domain; A.7 Model fitting to data; A.8 Principal component analysis; Chapter summary; Further reading; Index; A; B; C; D; E; F; G; H; I; L; M; N; O; P; Q; R; S; T; V; W |
| Record Nr. | UNINA-9910452690803321 |
Endres Robert G
|
||
| Oxford, : Oxford University Press, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Physical principles in sensing and signaling [[electronic resource] ] : with an introduction to modeling in biology / / Robert G. Endres
| Physical principles in sensing and signaling [[electronic resource] ] : with an introduction to modeling in biology / / Robert G. Endres |
| Autore | Endres Robert G |
| Pubbl/distr/stampa | Oxford, : Oxford University Press, 2013 |
| Descrizione fisica | 1 online resource (158 p.) |
| Disciplina |
571.43
571.634 |
| Soggetto topico |
Biology - Simulation methods
Biology - Mathematical models |
| ISBN |
1-283-85621-2
0-19-165428-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Contents; 1 Introduction; Chapter summary; Further reading; 2 Chemotaxis in bacterium Escherichia coli; 2.1 Chemical gradient sensing; 2.2 "Nose and brain": the receptor cluster; 2.3 E. coli chemotaxis pathway; 2.4 Experimental approaches; 2.5 Time-course data and dose-response curves; Chapter summary; Further reading; 3 Physical concepts; 3.1 Diffusion; 3.2 Boltzmann distribution; 3.3 Ligand-receptor binding; 3.4 Fluctuation-dissipation theorem; Chapter summary; Further reading; 4 Mathematical tools; 4.1 Ordinary differential equations; 4.2 Kinetic laws; 4.3 Master equation
4.4 Poisson distribution4.5 Waiting-time distribution; 4.6 Langevin small-noise approximation; 4.7 Information theory; Chapter summary; Further reading; 5 Signal amplification and integration; 5.1 Cooperativity by allostery; 5.2 Emergence of allostery from microscopic details; 5.3 Two-state equilibrium receptor model; 5.4 Monod-Wyman-Changeux model for receptor signaling; 5.5 Alternative Ising model for receptor cluster; Chapter summary; Further reading; 6 Robust precise adaptation; 6.1 Energy-landscape picture of adaptation; 6.2 Dynamics of adaptation; 6.3 Chemotactic response function 6.4 Integral-feedback control6.5 Assistance neighborhoods; Chapter summary; Further reading; 7 Polar receptor localization and clustering; 7.1 Trimer of dimers; 7.2 Elastic cluster-membrane model; 7.3 Polar receptor clustering; Chapter summary; Further reading; 8 Accuracy of sensing; 8.1 Perfectly absorbing sphere; 8.2 Perfectly monitoring sphere; 8.3 Sensing with cell-surface receptors; Chapter summary; Further reading; 9 Motor impulse response; 9.1 Impulse response; 9.2 Time and frequency domains; 9.3 Minimal pathway model; 9.4 Linear response approximation; 9.5 Noise power spectra Chapter summaryFurther reading; 10 Optimization of pathway; 10.1 Optimal receptor-complex size; 10.2 Optimal adaptation dynamics; Chapter summary; Further reading; 11 "Seeing like a bacterium"; 11.1 Typical chemical gradients; 11.2 Weber's law; 11.3 Perception; 11.4 Fold-change detection; 11.5 Matching relations; 11.6 Predicting typical stimuli; Chapter summary; Further reading; 12 Beyond E. coli chemotaxis; Chapter summary; Further reading; Appendix More techniques; A.1 Derivation of the fluctuation-dissipation theorem; A.2 Variational principles and the Euler-Lagrange equation A.3 Gillespie simulationsA.4 Fokker-Planck approximation; A.5 Derivation of the Langevin noise; A.6 Time versus frequency domain; A.7 Model fitting to data; A.8 Principal component analysis; Chapter summary; Further reading; Index; A; B; C; D; E; F; G; H; I; L; M; N; O; P; Q; R; S; T; V; W |
| Record Nr. | UNINA-9910779363403321 |
|
Endres Robert G
|
||
| Oxford, : Oxford University Press, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||