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Peptide and protein vaccines / / edited by Rossen Donev
Peptide and protein vaccines / / edited by Rossen Donev
Pubbl/distr/stampa Amsterdam, [Netherlands] : , : Academic Press, , 2015
Descrizione fisica 1 online resource (192 p.)
Disciplina 572.65
Collana Advances in Protein Chemistry and Structural Biology
Soggetto topico Peptides - Therapeutic use
Proteins - Therapeutic use
Peptide drugs
Soggetto genere / forma Electronic books.
ISBN 0-12-802869-6
0-12-802827-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Peptide and Protein Vaccines; Copyright; Contents; Contributors; Preface; References; Chapter 1: Peptide Immunotherapy in Vaccine Development: From Epitope to Adjuvant; 1. Introduction; 2. Cancer Vaccine; 3. Allergy Vaccine; 4. Alzheimerś Disease Vaccine; 5. Adjuvant and Delivery; 6. Perspectives and Conclusions; References; Chapter 2: The Use of Liposomes to Shape Epitope Structure and Modulate Immunogenic Responses of Peptide Vaccines Against...; 1. Introduction; 2. MPER: ASite of Vulnerability on HIV-1 Env and a Linear Epitope; 3. Structural Organization of MPER
3.1. Hydrophobicity Distribution3.2. MPER Peptide Structure; 4. Lipid Vesicles: Adjuvants and Devices to Shape MPER Structure; 4.1. Liposomes as Adjuvants; 4.2. The Lipid Bilayer as an MPER Scaffold; 5. Immunogenicity Studies of MPER-Derived Peptides in Liposomes; References; Chapter 3: Recombinant Lipoproteins as Novel Vaccines with Intrinsic Adjuvant; 1. Introduction; 2. Establishment of High Expression Recombinant Lipoprotein System; 3. The Lipid Structure of Lipoprotein; 4. Recombinant Lipoprotein with Intrinsic Adjuvant Properties
5. To Engineer Chimeric Lipoproteins with Intrinsic Adjuvant for Novel Vaccine Development6. Recombinant Chimeric Lipoproteins Can Activate BMDCs; 7. A Robustness Up- and Downstream Processes for Lipoprotein Production; 8. Recombinant Lipoprotein-Based Subunit Vaccine Induces High Titers of Neutralizing Antibody and Longer Memory Immune Re...; 9. Recombinant Lipidated Human Papillomavirus E7 Induces Cellular Immune Responses and Protective Immunity Against Cervic...; 10. Conclusion; Acknowledgment; References
Chapter 4: Perspective of Peptide Vaccine Composed of Epitope Peptide, CpG-DNA, and Liposome Complex Without Carriers1. Introduction; 2. Licensed Adjuvants; 3. CpG-DNA: Adjuvant; 4. Phosphodiester Bond CpG-DNA; 5. Liposomes: Adjuvants; 6. Adjuvants for Peptide Vaccine; 7. Peptide Vaccine Composed of Epitope Peptide, CpG-DNA, and Liposome Complex Without Carriers; 7.1. Antibody Production with Epitope Peptide, CpG-DNA, and Liposome Complex Without Carriers; 7.2. Prevention of Influenza A Virus Infection; 7.3. Prevention of Respiratory Syncytial Virus Infection
7.4. Cancer Vaccine Composed of Epitope Peptide, CpG-DNA, and Liposome Complex Without Carriers8. Perspectives; Acknowledgments; References; Chapter 5: Chemical Platforms for Peptide Vaccine Constructs; 1. Introduction; 2. Multiple Antigenic Peptide System Using a PolyLys Core: ABoon to Synthetic Peptide Vaccines; 3. Synthetic Antigen Carrier Bearing N-(S-acetylmercaptoacetyl)-Glutamyl Residues; 4. Thioester as a Replacement for Natural Peptide Bond (Chemical Ligation): Construction of Proteins; 5. Synthetic Peptide Dendrimer with Thiazolidinyl Pendant
6. Oxime Chemistry for Synthetic Peptide-Based Vaccines
Record Nr. UNINA-9910460999503321
Amsterdam, [Netherlands] : , : Academic Press, , 2015
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Peptide and protein vaccines / / edited by Rossen Donev
Peptide and protein vaccines / / edited by Rossen Donev
Pubbl/distr/stampa Amsterdam, [Netherlands] : , : Academic Press, , 2015
Descrizione fisica 1 online resource (192 p.)
Disciplina 572.65
Collana Advances in Protein Chemistry and Structural Biology
Soggetto topico Peptides - Therapeutic use
Proteins - Therapeutic use
Peptide drugs
ISBN 0-12-802869-6
0-12-802827-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Peptide and Protein Vaccines; Copyright; Contents; Contributors; Preface; References; Chapter 1: Peptide Immunotherapy in Vaccine Development: From Epitope to Adjuvant; 1. Introduction; 2. Cancer Vaccine; 3. Allergy Vaccine; 4. Alzheimerś Disease Vaccine; 5. Adjuvant and Delivery; 6. Perspectives and Conclusions; References; Chapter 2: The Use of Liposomes to Shape Epitope Structure and Modulate Immunogenic Responses of Peptide Vaccines Against...; 1. Introduction; 2. MPER: ASite of Vulnerability on HIV-1 Env and a Linear Epitope; 3. Structural Organization of MPER
3.1. Hydrophobicity Distribution3.2. MPER Peptide Structure; 4. Lipid Vesicles: Adjuvants and Devices to Shape MPER Structure; 4.1. Liposomes as Adjuvants; 4.2. The Lipid Bilayer as an MPER Scaffold; 5. Immunogenicity Studies of MPER-Derived Peptides in Liposomes; References; Chapter 3: Recombinant Lipoproteins as Novel Vaccines with Intrinsic Adjuvant; 1. Introduction; 2. Establishment of High Expression Recombinant Lipoprotein System; 3. The Lipid Structure of Lipoprotein; 4. Recombinant Lipoprotein with Intrinsic Adjuvant Properties
5. To Engineer Chimeric Lipoproteins with Intrinsic Adjuvant for Novel Vaccine Development6. Recombinant Chimeric Lipoproteins Can Activate BMDCs; 7. A Robustness Up- and Downstream Processes for Lipoprotein Production; 8. Recombinant Lipoprotein-Based Subunit Vaccine Induces High Titers of Neutralizing Antibody and Longer Memory Immune Re...; 9. Recombinant Lipidated Human Papillomavirus E7 Induces Cellular Immune Responses and Protective Immunity Against Cervic...; 10. Conclusion; Acknowledgment; References
Chapter 4: Perspective of Peptide Vaccine Composed of Epitope Peptide, CpG-DNA, and Liposome Complex Without Carriers1. Introduction; 2. Licensed Adjuvants; 3. CpG-DNA: Adjuvant; 4. Phosphodiester Bond CpG-DNA; 5. Liposomes: Adjuvants; 6. Adjuvants for Peptide Vaccine; 7. Peptide Vaccine Composed of Epitope Peptide, CpG-DNA, and Liposome Complex Without Carriers; 7.1. Antibody Production with Epitope Peptide, CpG-DNA, and Liposome Complex Without Carriers; 7.2. Prevention of Influenza A Virus Infection; 7.3. Prevention of Respiratory Syncytial Virus Infection
7.4. Cancer Vaccine Composed of Epitope Peptide, CpG-DNA, and Liposome Complex Without Carriers8. Perspectives; Acknowledgments; References; Chapter 5: Chemical Platforms for Peptide Vaccine Constructs; 1. Introduction; 2. Multiple Antigenic Peptide System Using a PolyLys Core: ABoon to Synthetic Peptide Vaccines; 3. Synthetic Antigen Carrier Bearing N-(S-acetylmercaptoacetyl)-Glutamyl Residues; 4. Thioester as a Replacement for Natural Peptide Bond (Chemical Ligation): Construction of Proteins; 5. Synthetic Peptide Dendrimer with Thiazolidinyl Pendant
6. Oxime Chemistry for Synthetic Peptide-Based Vaccines
Record Nr. UNINA-9910797252503321
Amsterdam, [Netherlands] : , : Academic Press, , 2015
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Peptide and protein vaccines / / edited by Rossen Donev
Peptide and protein vaccines / / edited by Rossen Donev
Pubbl/distr/stampa Amsterdam, [Netherlands] : , : Academic Press, , 2015
Descrizione fisica 1 online resource (192 p.)
Disciplina 572.65
Collana Advances in Protein Chemistry and Structural Biology
Soggetto topico Peptides - Therapeutic use
Proteins - Therapeutic use
Peptide drugs
ISBN 0-12-802869-6
0-12-802827-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Peptide and Protein Vaccines; Copyright; Contents; Contributors; Preface; References; Chapter 1: Peptide Immunotherapy in Vaccine Development: From Epitope to Adjuvant; 1. Introduction; 2. Cancer Vaccine; 3. Allergy Vaccine; 4. Alzheimerś Disease Vaccine; 5. Adjuvant and Delivery; 6. Perspectives and Conclusions; References; Chapter 2: The Use of Liposomes to Shape Epitope Structure and Modulate Immunogenic Responses of Peptide Vaccines Against...; 1. Introduction; 2. MPER: ASite of Vulnerability on HIV-1 Env and a Linear Epitope; 3. Structural Organization of MPER
3.1. Hydrophobicity Distribution3.2. MPER Peptide Structure; 4. Lipid Vesicles: Adjuvants and Devices to Shape MPER Structure; 4.1. Liposomes as Adjuvants; 4.2. The Lipid Bilayer as an MPER Scaffold; 5. Immunogenicity Studies of MPER-Derived Peptides in Liposomes; References; Chapter 3: Recombinant Lipoproteins as Novel Vaccines with Intrinsic Adjuvant; 1. Introduction; 2. Establishment of High Expression Recombinant Lipoprotein System; 3. The Lipid Structure of Lipoprotein; 4. Recombinant Lipoprotein with Intrinsic Adjuvant Properties
5. To Engineer Chimeric Lipoproteins with Intrinsic Adjuvant for Novel Vaccine Development6. Recombinant Chimeric Lipoproteins Can Activate BMDCs; 7. A Robustness Up- and Downstream Processes for Lipoprotein Production; 8. Recombinant Lipoprotein-Based Subunit Vaccine Induces High Titers of Neutralizing Antibody and Longer Memory Immune Re...; 9. Recombinant Lipidated Human Papillomavirus E7 Induces Cellular Immune Responses and Protective Immunity Against Cervic...; 10. Conclusion; Acknowledgment; References
Chapter 4: Perspective of Peptide Vaccine Composed of Epitope Peptide, CpG-DNA, and Liposome Complex Without Carriers1. Introduction; 2. Licensed Adjuvants; 3. CpG-DNA: Adjuvant; 4. Phosphodiester Bond CpG-DNA; 5. Liposomes: Adjuvants; 6. Adjuvants for Peptide Vaccine; 7. Peptide Vaccine Composed of Epitope Peptide, CpG-DNA, and Liposome Complex Without Carriers; 7.1. Antibody Production with Epitope Peptide, CpG-DNA, and Liposome Complex Without Carriers; 7.2. Prevention of Influenza A Virus Infection; 7.3. Prevention of Respiratory Syncytial Virus Infection
7.4. Cancer Vaccine Composed of Epitope Peptide, CpG-DNA, and Liposome Complex Without Carriers8. Perspectives; Acknowledgments; References; Chapter 5: Chemical Platforms for Peptide Vaccine Constructs; 1. Introduction; 2. Multiple Antigenic Peptide System Using a PolyLys Core: ABoon to Synthetic Peptide Vaccines; 3. Synthetic Antigen Carrier Bearing N-(S-acetylmercaptoacetyl)-Glutamyl Residues; 4. Thioester as a Replacement for Natural Peptide Bond (Chemical Ligation): Construction of Proteins; 5. Synthetic Peptide Dendrimer with Thiazolidinyl Pendant
6. Oxime Chemistry for Synthetic Peptide-Based Vaccines
Record Nr. UNINA-9910818574903321
Amsterdam, [Netherlands] : , : Academic Press, , 2015
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui