Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
High-performance gradient elution : the practical application of the linear-solvent-strength model / / Lloyd R. Snyder, John W. Dolan
| High-performance gradient elution : the practical application of the linear-solvent-strength model / / Lloyd R. Snyder, John W. Dolan |
| Autore | Snyder Lloyd R |
| Pubbl/distr/stampa | Hoboken, NJ, : John Wiley, c2007 |
| Descrizione fisica | 1 online resource (491 p.) |
| Disciplina | 543/.84 |
| Altri autori (Persone) | DolanJohn W |
| Soggetto topico | High performance liquid chromatography |
| ISBN |
1-280-72143-X
9786610721436 0-470-05552-9 0-470-05551-0 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
HIGH-PERFORMANCE GRADIENT ELUTION; CONTENTS; PREFACE; GLOSSARY OF SYMBOLS AND TERMS; 1 INTRODUCTION; 1.1 The "General Elution Problem" and the Need for Gradient Elution; 1.2 Other Reasons for the Use of Gradient Elution; 1.3 Gradient Shape; 1.4 Similarity of Isocratic and Gradient Elution; 1.4.1 Gradient and Isocratic Elution Compared; 1.4.2 The Linear-Solvent-Strength Model; 1.5 Computer Simulation; 1.6 Sample Classification; 1.6.1 Sample Compounds of Related Structure ("Regular Samples"); 1.6.2 Sample Compounds of Unrelated Structure ("Irregular" Samples); 2 GRADIENT ELUTION FUNDAMENTALS
2.1 Isocratic Separation2.1.1 Retention; 2.1.2 Peak Width and Plate Number; 2.1.3 Resolution; 2.1.4 Role of Separation Conditions; 2.1.4.1 Optimizing Retention [Term a of Equation (2.7)]; 2.1.4.2 Optimizing Selectivity α [Term b of Equation (2.7)]; 2.1.4.3 Optimizing the Column Plate Number N [Term c of Equation (2.7)]; 2.2 Gradient Separation; 2.2.1 Retention; 2.2.1.1 Gradient and Isocratic Separation Compared for "Corresponding" Conditions; 2.2.2 Peak Width; 2.2.3 Resolution; 2.2.3.1 Resolution as a Function of Values of S for Two Adjacent Peaks ("Irregular" Samples) 2.2.3.2 Using Gradient Elution to Predict Isocratic Separation2.2.4 Sample Complexity and Peak Capacity; 2.3 Effect of Gradient Conditions on Separation; 2.3.1 Gradient Steepness b: Change in Gradient Time; 2.3.2 Gradient Steepness b: Change in Column Length or Diameter; 2.3.3 Gradient Steepness b: Change in Flow Rate; 2.3.4 Gradient Range Δø: Change in Initial Percentage B (ø(0)); 2.3.5 Gradient Range Δø: Change in Final %B (ø(f)); 2.3.6 Effect of a Gradient Delay; 2.3.6.1 Equipment Dwell Volume; 2.3.7 Effect of Gradient Shape (Nonlinear Gradients) 2.3.8 Overview of the Effect of Gradient Conditions on the Chromatogram2.4 Related Topics; 2.4.1 Nonideal Retention in Gradient Elution; 2.4.2 Gradient Elution Misconceptions; 3 METHOD DEVELOPMENT; 3.1 A Systematic Approach to Method Development; 3.1.1 Separation Goals (Step 1 of Fig. 3.1); 3.1.2 Nature of the Sample (Step 2 of Fig. 3.1); 3.1.3 Initial Experimental Conditions; 3.1.4 Repeatable Results; 3.1.5 Computer Simulation: Yes or No?; 3.1.6 Sample Preparation (Pretreatment); 3.2 Initial Experiments; 3.2.1 Interpreting the Initial Chromatogram (Step 3 of Fig. 3.1) 3.2.1.1 "Trimming" a Gradient Chromatogram3.2.1.2 Possible Problems; 3.3 Developing a Gradient Separation: Resolution versus Conditions; 3.3.1 Optimizing Gradient Retention k* (Step 4 of Fig. 3.1); 3.3.2 Optimizing Gradient Selectivity α* (Step 5 of Fig. 3.1); 3.3.3 Optimizing the Gradient Range (Step 6 of Fig. 3.1); 3.3.3.1 Changes in Selectivity as a Result of Change in k*; 3.3.4 Segmented (Nonlinear) Gradients (Step 6 of Fig. 3.1 Continued); 3.3.5 Optimizing the Column Plate Number N* (Step 7 of Fig. 3.1); 3.3.6 Column Equilibration Between Successive Sample Injections 3.3.7 Fast Separations |
| Record Nr. | UNINA-9910143567103321 |
Snyder Lloyd R
|
||
| Hoboken, NJ, : John Wiley, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Introduction to modern liquid chromatography / / Lloyd R. Snyder, Joseph J. Kirkland, John W. Dolan
| Introduction to modern liquid chromatography / / Lloyd R. Snyder, Joseph J. Kirkland, John W. Dolan |
| Autore | Snyder Lloyd R |
| Edizione | [3rd ed. /] |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2010 |
| Descrizione fisica | xli, 912 p. : ill |
| Disciplina | 543/.84 |
| Altri autori (Persone) |
KirklandJ. J <1925-> (Joseph Jack)
DolanJohn W |
| Soggetto topico |
Liquid chromatography
Chromatographic analysis Cromatografia de líquids |
| Soggetto genere / forma | Llibres electrònics |
| ISBN |
9786612686832
9780470508176 0470508175 9780470508183 0470508183 9781282686830 1282686836 9781118210390 1118210395 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910208844503321 |
|
Snyder Lloyd R
|
||
| Hoboken, N.J., : Wiley, c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||