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Kidney cancer : recent advances in surgical and molecular pathology / / edited by Mukul K. Divatia, Ayhan Ozcan, Charles C. Guo, Jae Y. Ro
| Kidney cancer : recent advances in surgical and molecular pathology / / edited by Mukul K. Divatia, Ayhan Ozcan, Charles C. Guo, Jae Y. Ro |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
| Descrizione fisica | 1 online resource (xi, 445 pages) |
| Disciplina |
616.07
616.99461 |
| Soggetto topico |
Kidneys - Cancer - Molecular aspects
Cancer - Surgery Interventional radiology Pathology Urology Surgical Oncology Interventional Radiology |
| ISBN | 3-030-28333-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Surgical Considerations in Renal Tumors -- Renal Cell Carcinoma: The Oncologist’s Point of View -- Normal Anatomy and Histology of the Kidney: Importance for Kidney Tumors -- Benign Renal Epithelial / Epithelial and Stromal Tumors -- Major Subtypes of Renal Cell Carcinoma -- New and Emerging Subtypes of Renal Cell Carcinoma -- Renal Mass Biopsy -- Mesenchymal Kidney Tumors -- Pediatric Renal Tumors: Diagnostic Updates -- Neuroendocrine Kidney Tumors -- Hereditary Syndromes Associated with Kidney Tumors -- Lymphoid Neoplasms of the Kidney -- Tumors of the Renal Pelvis -- Non-Neoplastic Changes in Nephrectomy Specimens for Tumors -- Application of Immunohistochemistry in Diagnosis of Renal Cell Neoplasms -- Cytology of Kidney Tumors -- Diagnostic Imaging in Renal Tumors. Molecular Pathology of Kidney Tumors -- Targeted Treatment of Renal Cell Carcinoma -- Specimen Handling: Radical and Partial Nephrectomy Specimens -- Staging and Reporting of Renal Cell Carcinomas. |
| Record Nr. | UNINA-9910369953603321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Precision Molecular Pathology of Prostate Cancer / / edited by Brian D. Robinson, Juan Miguel Mosquera, Jae Y. Ro, Mukul Divatia
| Precision Molecular Pathology of Prostate Cancer / / edited by Brian D. Robinson, Juan Miguel Mosquera, Jae Y. Ro, Mukul Divatia |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (570 pages) : illustrations (some color), charts |
| Disciplina | 616.99463075 |
| Collana | Molecular Pathology Library |
| Soggetto topico |
Pathology
Oncology Urology |
| ISBN | 3-319-64096-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I. General principles -- Approach to patient -- Etiology -- Precursor and pre-invasive lesions of prostate cancer -- Prostatic adenocarcinoma: morphologic spectrum, Gleason scoring, etc -- Genetic susceptibility -- DNA damage repair, BRCA mutations, DNA adducts, SNPs -- Racial differences -- Cancer stem cells Part II. Molecular signatures of primary prostate cancer -- SNPs -- Copy number variation/chromosomal aberration (PTEN deletion, etc.) -- Gene fusions (TMPRSS2:ERG, etc.) -- Gene expression arrays -- Next generation sequencing (point mutations, indels, etc.) -- Epigenetic changes (chromatin remodeling, etc.) -- Proteomics -- Metabolomics -- miRNA and lncRNA Part III. Molecular signatures of advanced prostate cancer -- Lymph node metastasis -- Bone metastasis a -- RANKL, Src kinases, endothelins, bisphosphonates -- Visceral metastasis a -- Role of extracellular matrix, angiogenesis, epithelial-mesenchymal transition (EMT), inflammation -- Castration resistant prostate cancer (CRPC) -- Neuroendocrine prostate cancer (NEPC) Part IV. Key molecular pathways in prostate cancer development and progression -- Androgen receptor in carcinogenesis -- Androgen receptor in progression (CRPC) -- PI3K/Akt/mTOR/PTEN and ERK/MAPK pathways -- Cell cycle regulators (p53, etc.) -- DNA damage repair -- Tyrosine kinase signaling (EGFR, VEGFR, PDGFR, FGFR, IGFR, etc.) -- Cytoskeletal function (microtubules and taxane therapy) Part V. Precision medicine approach: Diagnosis, treatment, prognosis -- Molecular diagnosis -- Molecular imaging -- Molecular prognostic markers/tests -- Molecular targeted therapies -- Towards molecular classification of prostate cancer. |
| Record Nr. | UNINA-9910300279403321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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