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The science and ethics of antipsychotic use in children / / edited by Nina Di Pietro and Judy Illes ; contributors, Mai Berger [and twenty others]
| The science and ethics of antipsychotic use in children / / edited by Nina Di Pietro and Judy Illes ; contributors, Mai Berger [and twenty others] |
| Pubbl/distr/stampa | Amsterdam, [Netherlands] : , : Academic Press, , 2015 |
| Descrizione fisica | 1 online resource (228 p.) |
| Disciplina | 615.7882 |
| Soggetto topico |
Antipsychotic drugs
Children - Drug use |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; The Science and Ethics of Antipsychotic Use in Children; Copyright; Contents; Contributors; Foreword; Acknowledgments; Introduction: A Call for Partnership; References; Chapter 1: A Brief History of the Science and Ethics of Antipsychotics and Off-Label Prescribing; A New Era in Psychopharmacology Research Begins; A Second Generation Emerges; The Expansion of Antipsychotics: Off-Label Use in Children; Benefits in the Face of Risks; A Call for Partnership; References; Chapter 2: Pharmacoepidemiology of Antipsychotic Use in Canadian Children and Adolescents; Introduction
Differences in SGA Regulation Between Canada and Other CountriesCanadian Second-Generation Antipsychotic Medications Prescription Trends for Children and Adolescents; National Prescribing Trends; Provincial Prescribing Trends; Manitoba; Nova Scotia; British Columbia; Comparing Canadian SGA Prescription Trends to those in Other Countries; Conclusions; References; Chapter 3: Do We Know If They Work and If They Are Safe: Second-Generation Antipsychotics for Treatment of Autism Spectrum ...; Introduction; Methods; Efficacy of SGAs for Children and Adolescents With ASDs Efficacy of SGAs for Children and Adolescents With DBDsSummary of Adverse Effects and Safety Data from ASD and DBD Trials Combined; Discussion; SGAs Included in RCTs; Efficacy in ASD Trials; Efficacy in DBD trials; Critique and Ethical Considerations; Conclusion; References; ASD Studies: Aripiprazole; ASD Studies: Olanzapine; ASD Studies: Risperidone; DBD Studies: Aripiprazole; DBD Studies: Quetiapine; DBD Studies: Risperidone; Chapter 4: Ensuring the Safety of Children Treated with Second-Generation Antipsychotics; Introduction; Side Effects associated with SGA use in Children and Youth Monitoring the Health of Children and Youth on SGAsGuidelines for Metabolic Monitoring; Recommendations for Monitoring Metabolic Changes; Height; Weight; Body Mass Index; Waist Circumference; Blood Pressure; Management of Metabolic Complications; Why Standardized Metabolic Monitoring Matters; Improving Patient Care; Educating Families; Overcoming Barriers to Completion of Monitoring; Conclusion; References; Chapter 5: Pediatric Clinical Trial Activity for Antipsychotics and the Sharing of Results: A Complex Ethical Landscape; Introduction; Patient Safety, Ethics, and Clinical Trial Regulation The Push for Pediatric Clinical TrialsThe Push for Clinical Trial Registration; Reporting of Results; Mapping the Landscape: Clinical Trials for Antipsychotics in Children and Youth; Methods; Results; Reflections On The Current State Of Pediatric Clinical Trials For Antipsychotics; The Landscape of Clinical Trial Activity; Developmental Gaps; The Strength of Evidence; Uniformity in Outcome Measures; Gaps in Results Reporting; Recruitment and Willingness to Participate in Research; Informed Consent; Limitations; Recommendations; References Chapter 6: Pathways to Overmedication and Polypharmacy: Case Examples from Adolescents with Fetal Alcohol Spectrum Disorders |
| Record Nr. | UNINA-9910788115303321 |
| Amsterdam, [Netherlands] : , : Academic Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The science and ethics of antipsychotic use in children / / edited by Nina Di Pietro and Judy Illes ; contributors, Mai Berger [and twenty others]
| The science and ethics of antipsychotic use in children / / edited by Nina Di Pietro and Judy Illes ; contributors, Mai Berger [and twenty others] |
| Pubbl/distr/stampa | Amsterdam, [Netherlands] : , : Academic Press, , 2015 |
| Descrizione fisica | 1 online resource (228 p.) |
| Disciplina | 615.7882 |
| Soggetto topico |
Antipsychotic drugs
Children - Drug use |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; The Science and Ethics of Antipsychotic Use in Children; Copyright; Contents; Contributors; Foreword; Acknowledgments; Introduction: A Call for Partnership; References; Chapter 1: A Brief History of the Science and Ethics of Antipsychotics and Off-Label Prescribing; A New Era in Psychopharmacology Research Begins; A Second Generation Emerges; The Expansion of Antipsychotics: Off-Label Use in Children; Benefits in the Face of Risks; A Call for Partnership; References; Chapter 2: Pharmacoepidemiology of Antipsychotic Use in Canadian Children and Adolescents; Introduction
Differences in SGA Regulation Between Canada and Other CountriesCanadian Second-Generation Antipsychotic Medications Prescription Trends for Children and Adolescents; National Prescribing Trends; Provincial Prescribing Trends; Manitoba; Nova Scotia; British Columbia; Comparing Canadian SGA Prescription Trends to those in Other Countries; Conclusions; References; Chapter 3: Do We Know If They Work and If They Are Safe: Second-Generation Antipsychotics for Treatment of Autism Spectrum ...; Introduction; Methods; Efficacy of SGAs for Children and Adolescents With ASDs Efficacy of SGAs for Children and Adolescents With DBDsSummary of Adverse Effects and Safety Data from ASD and DBD Trials Combined; Discussion; SGAs Included in RCTs; Efficacy in ASD Trials; Efficacy in DBD trials; Critique and Ethical Considerations; Conclusion; References; ASD Studies: Aripiprazole; ASD Studies: Olanzapine; ASD Studies: Risperidone; DBD Studies: Aripiprazole; DBD Studies: Quetiapine; DBD Studies: Risperidone; Chapter 4: Ensuring the Safety of Children Treated with Second-Generation Antipsychotics; Introduction; Side Effects associated with SGA use in Children and Youth Monitoring the Health of Children and Youth on SGAsGuidelines for Metabolic Monitoring; Recommendations for Monitoring Metabolic Changes; Height; Weight; Body Mass Index; Waist Circumference; Blood Pressure; Management of Metabolic Complications; Why Standardized Metabolic Monitoring Matters; Improving Patient Care; Educating Families; Overcoming Barriers to Completion of Monitoring; Conclusion; References; Chapter 5: Pediatric Clinical Trial Activity for Antipsychotics and the Sharing of Results: A Complex Ethical Landscape; Introduction; Patient Safety, Ethics, and Clinical Trial Regulation The Push for Pediatric Clinical TrialsThe Push for Clinical Trial Registration; Reporting of Results; Mapping the Landscape: Clinical Trials for Antipsychotics in Children and Youth; Methods; Results; Reflections On The Current State Of Pediatric Clinical Trials For Antipsychotics; The Landscape of Clinical Trial Activity; Developmental Gaps; The Strength of Evidence; Uniformity in Outcome Measures; Gaps in Results Reporting; Recruitment and Willingness to Participate in Research; Informed Consent; Limitations; Recommendations; References Chapter 6: Pathways to Overmedication and Polypharmacy: Case Examples from Adolescents with Fetal Alcohol Spectrum Disorders |
| Record Nr. | UNINA-9910819137803321 |
| Amsterdam, [Netherlands] : , : Academic Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||