Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
5-HT2A Receptors in the Central Nervous System / / edited by Bruno P. Guiard, Giuseppe Di Giovanni
| 5-HT2A Receptors in the Central Nervous System / / edited by Bruno P. Guiard, Giuseppe Di Giovanni |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Humana, , 2018 |
| Descrizione fisica | 1 online resource (446 pages) : illustrations |
| Disciplina | 612.8042 |
| Collana | The Receptors |
| Soggetto topico |
Neurosciences
Neurobiology |
| ISBN | 3-319-70474-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910298430903321 |
| Cham : , : Springer International Publishing : , : Imprint : Humana, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Extrasynaptic GABAA Receptors / / edited by Adam C. Errington, Giuseppe Di Giovanni, Vincenzo Crunelli
| Extrasynaptic GABAA Receptors / / edited by Adam C. Errington, Giuseppe Di Giovanni, Vincenzo Crunelli |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (301 p.) |
| Disciplina | 616.8 |
| Collana | The Receptors |
| Soggetto topico |
Neurosciences
Pharmacology Neurology Pharmacology/Toxicology Neurology |
| ISBN | 1-4939-1426-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | A brief introduction to extrasynaptic GABAA receptors and ‘tonic’ GABAA receptor mediated inhibition in physiology and disease -- Extrasynaptic GABAA receptors: subunit composition, distribution, and regulation -- Biophysical properties of recombinant 2- AND δ- subunit containing GABAA receptors -- The pharmacology of extrasynaptic GABAA receptors -- Neurosteroids and extrasynaptic GABAA receptors -- Sources of GABA that activate extrasynaptic GABAA receptors -- Modulation of Extrasynaptic GABAA Receptors by G-protein-coupled Receptors -- Extrasynaptic GABAA receptors and tonic inhibition in spinal cord -- The role of peri-synaptic GABA receptors after stroke -- The role of extrasynaptic GABAA receptors in focal epilepsy -- Gain-of-Function of Thalamic Extrasynaptic GABA-A Receptors in Typical Absence Seizures -- GABAergic control of the hypothalamic-pituitary-adrenal (HPA) axis: role of extrasynaptic GABAA receptors -- Tonic GABAA receptor mediated inhibition in Fragile-X Syndrome: A cause of dysfunction or a pathway for a cure? |
| Record Nr. | UNINA-9910298341003321 |
| New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
G-Protein-Coupled Receptor Dimers / / edited by Katharine Herrick-Davis, Graeme Milligan, Giuseppe Di Giovanni
| G-Protein-Coupled Receptor Dimers / / edited by Katharine Herrick-Davis, Graeme Milligan, Giuseppe Di Giovanni |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Humana, , 2017 |
| Descrizione fisica | 1 online resource (XVII, 501 p. 70 illus., 58 illus. in color.) |
| Disciplina | 612.8 |
| Collana | The Receptors |
| Soggetto topico | Neurosciences |
| ISBN | 3-319-60174-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I. Introduction -- 1. From Monomers to Dimers and Beyond: An Exciting Journey in the World of the G protein-coupled Receptor Family.- 2. The use of Spatial Intensity Distribution Analysis to Examine G protein-coupled Receptor Oligomerization -- 3. Advanced Microscopy Techniques for Studying G protein-coupled Receptors.- Part II. Receptors.- 4. Light Sensing G protein-coupled Receptor Rhodopsin Dimer -- 5. Extreme Vetting of Dopamine Receptor Oligomerization -- 6. Serotonin receptors.- 7. Cannabinoid and Opioid Receptor Heteromers -- 8. Di/oligomerization of Glycoprotein Hormone Receptors.- 9. Chemokine Receptor Oligomerization to Tweak Chemotactic Responses -- 10. Secretin Receptor Dimerization. Prototypic of Class B GPCR Behavior.- 11. Receptors and RAMPs -- 12. Obligatory Heterodimerization of GABAB Receptor.- 13. Metabotropic Glutamate Receptors. Part III. Assembly and Trafficking.- 14. The monomer/homodimer Equilibrium of G protein-coupled Receptors: Formation in the Secretory Pathway and Potential Functional Significance.- 15. Probing Self-assembly of G protein-coupled Receptor Oligomers in Membranes using Molecular Dynamics Modeling and Experimental Approaches.- 16. Interaction of Membrane Cholesterol with GPCRs: Implications in Receptor Oligomerization.- Part IV. Physiology and Therapeutic Potential.- 17. Allosterism within GPCR Oligomers: Back to Symmetry.- 18. Understanding the Physiological Significance of GPCR Dimers and Oligomers -- 19. Heteromers form Novel Signaling Complexes -- 20. Heteroreceptor Complexes Implicated in Parkinson’s Disease. |
| Record Nr. | UNINA-9910253940503321 |
| Cham : , : Springer International Publishing : , : Imprint : Humana, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
mGLU Receptors / / edited by Richard Teke Ngomba, Giuseppe Di Giovanni, Giuseppe Battaglia, Ferdinando Nicoletti
| mGLU Receptors / / edited by Richard Teke Ngomba, Giuseppe Di Giovanni, Giuseppe Battaglia, Ferdinando Nicoletti |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Humana, , 2017 |
| Descrizione fisica | 1 online resource (X, 282 p. 28 illus., 26 illus. in color.) |
| Disciplina | 612.8 |
| Collana | The Receptors |
| Soggetto topico | Neurosciences |
| ISBN | 3-319-56170-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | mGlu5 Signalling: A Target for Addiction Therapeutics? -- Supraspinal Metabotropic Glutamate Receptors: An Endogenous Substrate for Alleviating Chronic Pain and Related Affective Disorders -- Metabotropic Glutamate Receptors and Parkinson's Disease: Basic and Preclinical Neuroscience -- Metabotropic Glutamate 2 (mGlu2) Receptors and Schizophrenia Treatment -- mGlu5: A Metabotropic Glutamate Receptor at the Hub of Hippocampal Information Processing, Persistent Synaptic Plasticity and Long-Term Memory -- Neuroprotective Properties of Glutamate Metabotropic Glutamate Receptors in Parkinson’s Disease and Other Brain Disorders -- Structure, Dynamics and Modulation of Metabotropic Glutamate Receptors -- Metabotropic Glutamate Receptor Function in Thalamocortical Circuitry -- Metabotropic Glutamate Receptors in Cancer -- mGlu5 Receptors in Parkinson’s Disease and MPTP-Lesioned Monkeys: Behaviour and Brain Molecular Correlates -- Is There a Future for PAMs of Group I mGluR in Absence Epilepsy? -- Regulation of Hippocampal mGluR-Dependent Long-Term Depression by GluA2-Dependent Cofilin-Mediated Actin Remodeling -- Metabotropic Glutamate Receptors in Amygdala Functions. |
| Record Nr. | UNINA-9910253942203321 |
| Cham : , : Springer International Publishing : , : Imprint : Humana, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Nicotine addiction [[electronic resource] ] : prevention, health effects and treatment options / / Giuseppe Di Giovanni, editor
| Nicotine addiction [[electronic resource] ] : prevention, health effects and treatment options / / Giuseppe Di Giovanni, editor |
| Pubbl/distr/stampa | [Hauppauge] N.Y., : Nova Science Publishers, Inc., 2012 |
| Descrizione fisica | 1 online resource (295 p.) |
| Disciplina | 616.86/5 |
| Altri autori (Persone) | Di GiovanniGiuseppe |
| Collana | Substance abuse assessment, interventions and treatment |
| Soggetto topico |
Nicotine addiction - Prevention
Nicotine addiction - Treatment |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-62081-344-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910453057303321 |
| [Hauppauge] N.Y., : Nova Science Publishers, Inc., 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Nicotine addiction [[electronic resource] ] : prevention, health effects and treatment options / / Giuseppe Di Giovanni, editor
| Nicotine addiction [[electronic resource] ] : prevention, health effects and treatment options / / Giuseppe Di Giovanni, editor |
| Pubbl/distr/stampa | [Hauppauge] N.Y., : Nova Science Publishers, Inc., 2012 |
| Descrizione fisica | 1 online resource (295 p.) |
| Disciplina | 616.86/5 |
| Altri autori (Persone) | Di GiovanniGiuseppe |
| Collana | Substance abuse assessment, interventions and treatment |
| Soggetto topico |
Nicotine addiction - Prevention
Nicotine addiction - Treatment |
| ISBN | 1-62081-344-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910779784103321 |
| [Hauppauge] N.Y., : Nova Science Publishers, Inc., 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Nicotine addiction : prevention, health effects and treatment options / / Giuseppe Di Giovanni, editor
| Nicotine addiction : prevention, health effects and treatment options / / Giuseppe Di Giovanni, editor |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | [Hauppauge] N.Y., : Nova Science Publishers, Inc., 2012 |
| Descrizione fisica | 1 online resource (295 p.) |
| Disciplina | 616.86/5 |
| Altri autori (Persone) | Di GiovanniGiuseppe |
| Collana | Substance abuse assessment, interventions and treatment |
| Soggetto topico |
Nicotine addiction - Prevention
Nicotine addiction - Treatment |
| ISBN | 1-62081-344-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Contents -- Preface -- Chapter 1 -- Nicotine Addiction and Treatment: Recent Advances -- Abstract -- Introduction -- Nicotine Addiction -- Involvement of Nicotinic Acetylcholine Receptors -- Involvement of Neurotransmitters -- Dopamine -- Glutamate -- GABA -- Endocanabinoid System -- Endogenous Opioid System -- 5-HT -- Norepinephrine -- Involvement of Monoamine Oxidase -- Neuronal Function -- Health Effects -- Prevention -- Therapeutic Option -- Nicotine Therapy -- Non-Nicotine Therapy -- Bupropion -- Varenicline -- Nicotine Vaccine -- Research Advances -- Conclusion -- Acknowledgment -- References -- Chapter 2 -- Serotonin-Dopamine Interaction in Nicotine Addiction: Focus on 5-HT2C Receptors -- Abstract -- Introduction -- Dopamine Systems -- Serotonin Systems -- 5-HT Receptors Localization -- The 5-HT2 Receptor Family -- Effects of Nicotine on Central Dopaminergic Function -- Effects of Nicotine on Central Serotonergic Function -- Serotonin 2C (5-HT2C) and Nicotine Rewarding Properties -- Serotonergic Drug Treatment for Smoking Cessation -- Conclusion -- Acknowledgments -- References -- Chapter 3 -- Defining the Role of the Hippocampus in Nicotine Addiction -- Abstract -- Introduction -- Canonical View of Reward and Addiction -- Connectivity between the Hippocampus and the Reward Circuitry -- Nicotine-Associated Contexts and Cues -- Hippocampal Nicotinic Acetylcholine Receptors, Plasticity and Addiction -- Hippocampus, Stress and Withdrawal -- Towards a Hippocampus Model for Nicotine Addiction -- Acknowledgments -- References -- Chapter 4 -- Nicotine, Neurodegeneration, and Neuroprotection in Neuropsychiatric Disorders -- Abstract -- Introduction -- Nicotine Neuroprotection -- in Neurodegenerative Diseases -- Nicotine and Alzheimer's Disease -- Nicotine Influence on Cognitive Impairment.
Nicotine, the Cholinergic System and Alzheimer's Disease -- Nicotine and Parkinson's Disease -- Nicotine and the Pathology of Parkinson's Disease -- Nicotine and other Memory Disorders -- Nicotine Neuroprotection in Neural Injury -- Nicotine Neuroprotection in Psychiatric Disorders -- Nicotine and Schizophrenia -- Nicotinic Acetylcholine Receptors in Schizophrenia -- Auditory Evoked Potential Inhibition Deficits in Schizophrenia -- Smooth Pursuit Eye Movement Deficits in Schizophrenia -- Prepulse Inhibition of Startle Response Deficits in Schizophrenia -- Neuropsychological Impairments in Schizophrenia -- Pharmacologic Interventions Targeting the Nicotinic Acetylcholine System -- Nicotine and Bipolar Mood Disorder -- Symptom Progression in Smoking Bipolar Patients -- Genetics of Bipolar Disorder and Nicotinic Acetylcholine Receptors -- Conclusion -- References -- Chapter 5 -- Stress as a Risk Factor for Transition to Heightened Nicotine Intake: Evidence from a Rat Model of Nicotine Self-Administration -- Abstract -- Introduction -- Materials and Methods -- Subjects -- Self-Administration Apparatus -- Food Training -- Surgery -- Nicotine Self-Administration -- Effect of Pharmacological Stress on Nicotine Intake -- Statistical Analyses -- Results -- Nicotine Self-Administration in the LNT and HNT Rats -- Effect of Yohimbine on Nicotine Self-Administration in the LNT Rats -- Effect of Yohimbine on Nicotine Self-Administration in the HNT Rats -- Effect of Yohimbine in Saline-Trained Rats -- Discussion -- Conclusion -- Acknowledgments -- References -- Chapter 6 -- Smoking, Nicotine and Depression: A Review -- Abstract -- Introduction -- General Aspects of Nicotine -- Pharmacology -- Metabolism -- Nicotinic Receptors -- General Characteristics of Depression -- Smoking, Nicotine and Depression -- Epidemiology. Hypothesis on the Increase in Indexes of Smoking among Patients with Major Depression -- Interaction Mechanisms of Nicotine in Depressive Disorders -- Conclusion -- References -- Chapter 7 -- New Psychological Approaches in Nicotine Addiction -- Abstract -- Introduction -- Prevention -- Cessation -- Relapse Prevention -- Conclusion -- References -- Chapter 8 -- Cognitive Consequences of Adolescent and Adult Nicotine Exposure: Utility of Animal Models -- Abstract -- Introduction -- Benefits of Rat Models for Studying Developmental Processes in Drug Addiction -- The Utility of the Rat as an Experimental Model of Adolescent Nicotine Exposure -- Hallmarks of Adolescence in the Rat -- Effects of Adult Nicotine Exposure on Cognition in Animals -- Effects of Adolescent Nicotine Exposure on Neural Development and Cognition in Animals -- Conclusion -- Acknowledgments -- References -- Chapter 9 -- Psychosocial Risk Factors for Smoking and Nicotine Dependence: Implications for Prevention and Treatment -- Abstract -- Introduction -- Purpose of Study -- Background -- Properties and Effects of Nicotine -- Mechanism of Nicotine Dependence -- Theoretical Framework -- Neurobiological Model -- Associative Learning Model -- Depression -- Smoking Expectancies -- The Personality Trait of Neuroticism -- Childhood Adversity -- Methodology of the Study -- Sample -- Measures -- Data Collection -- Results -- Conclusion -- Implications for Treatment: Assessment -- Nicotine Replacement Therapy -- Anti-Depressant Therapy -- Varencline -- Strategies to Motivate Change and Prevent Relapse -- Case Study -- Further Recommendations -- References -- Chapter 10 -- Effects Associated with the Structure of Adsorbents on the Degrees to Which Nicotine, Tar and CO are Reduced in Tobacco Smoke -- Abstract -- Introduction. Novel Materials Efficient For Reducing Nicotine, Tar and CO Contents -- Preparation of Cigarette Samples -- Composite Filter -- Chemical Composition of the Mainstream Tobacco Smoke -- Efficiency of the Sorption Removal -- The Factor of Selectivity -- Specific Sorption Capacity of Investigated Material -- The Effects of a Hydrophilic Type Zeolite on the Degree of Reduction of Nicotine, Tar and CO in Tobacco Smoke -- The Effects Associated with the Degree of Hydrophobicity of the Zeolite on the Degree of Reduction of Tobacco Smoke Components -- The Effects Associated With the Type of Amorphous Material on the Degree of Reduction of Tobacco Smoke Components -- Conclusion -- Acknowledgment -- References -- Chapter 11 -- Kinetics of Nicotine Bonding Onto and Release from Poly (Acrylic -co-Methacrylic Acid) Hydrogel -- Abstract -- Introduction -- Poly(Acrylic Acid-Cco-Methacrylic Acid) Hydrogel Synthesis -- Nicotine Bonding and Release -- Poly(Acrylic Acid-co-methacrylic Acid) Hydrogel Synthesis -- Nicotine Bonding -- Nicotine Release -- Isothermal Kinetics of Nicotine Bonding and Release -- Models of Kinetic Nicotine Bonding to the Hydrogel -- The Kinetics Model of Nicotine Release from the Hydrogel -- Conclusion -- Acknowledgment -- References -- Index -- Blank Page. |
| Record Nr. | UNINA-9910825971903321 |
| [Hauppauge] N.Y., : Nova Science Publishers, Inc., 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||