Biochemistry of cardiovascular dysfunction in obesity / / Paramjit S. Tappia, Sukhwinder K. Bhullar, Naranjan S. Dhalla, editors |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2020] |
Descrizione fisica | 1 online resource (XV, 401 p. 55 illus., 48 illus. in color.) |
Disciplina | 616.1 |
Collana | Advances in Biochemistry in Health and Disease |
Soggetto topico | Cardiovascular system - Diseases |
ISBN | 3-030-47336-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Biochemistry of cardiovascular dysfunction in obesity -- Vascular mechanisms linking RAAS components to obesity-associated hypertension -- Mechanisms of obesity-induced hypertension in adolescents -- Role of the sympathetic nervous system in obesity-induced hypertension -- Sex differences in the mechanisms associated with obesity-induced hypertension -- Leptin as a mediator of obesity-induced hypertension -- Endothelial dysfunction in obesity -- Neurohormonal regulation of sympathoexcitation and hypertension in obesity -- Role of obesity in hypertension in children -- Small for gestational age and obesity associated co-morbidities -- Obesity-Related Hypertension in Children -- The relationship between obesity and hypertension -- Hypertension in Obesity and the Impact of Weight Loss -- Parallels in the Evolution of Obesity and Hypertension -- Obesity and hypertension -- The microcirculation: a key player in obesity-associated cardiovascular disease -- Sex Differences in Leptin Control of Cardiovascular Function in Health and Metabolic Diseases -- Sex differences in the role of leptin and coronary heart disease -- Differential effect of subcutaneous abdominal and visceral adipose tissue on cardiometabolic risk -- Sex differences in lipid and lipoprotein metabolism -- Sex differences in the mechanisms of obesity-induced hypertension -- Impaired cardiac function in obese individuals -- Role of Vitamin D deficiency in cardiac function -- Obesity in advanced heart failure -- Cardiovascular morbidity and mortality associated with obesity -- Risk of overweight with the development of heart failure -- Obesity and heart failure -- Obesity phenotypes and their paradoxical association with cardiovascular diseases -- Mechanisms of heart failure with preserved ejection fraction in obesity -- Obesity and cardiovascular diseases -- Obesity and Heart Failure: Possible mechanisms of the Obesity Paradox -- Prognosis of morbid obesity patients with advanced heart failure -- BMI as a risk factor for cardiovascular disease -- Relationship between BMI and cardiovascular outcomes in diabetic patients -- Cardiometabolic risk in obese children -- Gender related differences in obesity associated cardiovascular complications -- Understanding the mechanisms and clinical significance of the obesity paradox -- Advances in understanding gender difference in cardiometabolic disease risk -- Cardiovascular and Metabolic Complications – Diagnosis and Management in Obese Children -- Obesity and Ventricular Repolarization. |
Record Nr. | UNINA-9910424634603321 |
Cham, Switzerland : , : Springer, , [2020] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Biomedical Translational Research : Drug Design and Discovery / / edited by R.C. Sobti, Naranjan S. Dhalla |
Edizione | [1st ed. 2022.] |
Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2022 |
Descrizione fisica | 1 online resource (597 pages) |
Disciplina | 610.28 |
Soggetto topico |
Medicine - Research
Biology - Research Drugs - Design Pharmaceutical chemistry Genomics Bioinformatics Biomedical Research Structure-Based Drug Design Pharmaceutics Disseny de medicaments Enginyeria biomèdica |
Soggetto genere / forma | Llibres electrònics |
ISBN | 981-16-9232-7 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Chapter 1. Emerging Technologies : Gateway to Understand Molecular Insight of Diseases, Newer Drugs, Their Design and Targeting -- Chapter 2. Polypharmacology: New Paradigms in Drug Development -- Chapter 3. Drug Repurposing in Biomedical Research : Benefits and Challenges -- Chapter 4. Computational Methods for Drug Repurposing -- Chapter 5. Genomic Approaches for Drug Repositioning -- Chapter 6. Organ-On-A- Chip: Novel in-Vitro Model For Drug Discovery -- Chapter 7. Precision Radiomolecular Oncology: Challenging the Classical Statistical Evidence Based Medicine -- Chapter 8. Drug Repositioning of the Phenylpiperazine Derivative Naftopidil in Prostate Cancer Treatment -- Chapter 9. Biomarker Based Drug Discovery and Reverse Translational Approach -- Chapter 10. Nanotechnology in Dentistry -- Chapter 11. Nanoparticles a Potential Breakthrough in Counteracting Multidrug-Resistant Bacterial Infections: A Holistic View on Underlying Mechanisms and Antibacterial Properties -- Chapter 12. Emerging Role of Cannabinoid System Modulators in Treatment of Cancer -- Chapter 13. Nanodrugs : A Futuristic Approach for Treating Nephrolithiasis -- Chapter 14. Lipo Dermaceuticals : Technological Transformation -- Chapter 15. The Importance of Drug Dose Adjustment in Elderly Patients with Special Considerations for Patients on Diverse Co-Medications and Antidepressants -- Chapter 16. Role of Microfluidics and Nano Fluidics in Managing CAD -- Chapter 17. Targeted Gene Delivery Through Magnetofection: The New Face of Medicine -- Chapter 18. Qbd-Steered Systematic Development of Drug Delivery Nanoconstructs : Vital Precepts, Retrospect and Prospects -- Chapter 19. Nanoemulsions: A Potential Advanced Nanocarrier Platform for Herbal Drug Delivery -- Chapter 20. Sirna Encapsulated Nanoparticles for Targeting Dorsal Root Ganglion (Drg) in Diabetic Neuropathic Pain -- Chapter 21. EGFR Targeted Quinazoline Clubbed Heterocycles as Anti-Cancer Agents. Chapter 22. Therapeutic Human Monoclonal Antibodies -- Chapter 23. Hydroxyapatites and Their Biomedical Applications -- Chapter 24. Recent Progress in Applications of Magnetic Nanoparticles in Medicine: A Review -- Chapter 25. Chimeric Antigen Receptor T-Cell Therapy: A Cutting Edge Therapy for Multiple Myeloma -- Chapter 26. Nanoparticles-Associated Lipopeptides: A New Class of Antimicrobials -- Chapter 27. Antimicrobial Applications of Engineered Metal-Based Nanomaterials -- Chapter 28. Strengthening Immunity-Ayurveda & Medicinal Plants -- Chapter 29. The Pathophysiology of Liver Disorders and Pharmacotherapy Options with Special Reference to Traditional Herbal Medicines: A Comprehensive Review -- Chapter 30. Polymeric Vehicles for Controlled Delivery of Ayurvedic Drugs for Wound Management. |
Record Nr. | UNINA-9910585974703321 |
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Cellular and biochemical mechanisms of obesity / / Paramjit S. Tappia, Bram Ramjiawan and Naranjan S. Dhalla, editors |
Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
Descrizione fisica | 1 online resource (420 pages) |
Disciplina | 574.192 |
Collana | Advances in biochemistry in health and disease |
Soggetto topico |
Biochemistry
Obesitat Trastorns del metabolisme |
Soggetto genere / forma | Llibres electrònics |
ISBN | 3-030-84763-2 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910513582303321 |
Cham, Switzerland : , : Springer, , [2021] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Diabetic cardiomyopathy : biochemical and molecular mechanisms / / Belma Turan, Naranjan S. Dhalla, editors |
Edizione | [1st ed. 2014.] |
Pubbl/distr/stampa | New York : , : Springer, , 2014 |
Descrizione fisica | 1 online resource (xix, 416 pages) : illustrations (some color) |
Disciplina | 616.1071 |
Collana | Advances in Biochemistry in Health and Disease |
Soggetto topico |
Myocardium - Diseases - Pathophysiology
Diabetes - Complications Clinical biochemistry |
ISBN | 1-4614-9317-X |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Cardiac defects in diabetes -- Hormonal imbalance and neuropathy -- Role of oxidative stress -- Role of cation channel defects -- Abnormalities in glucose transport -- Fatty acid utilization -- Sarcolemmal Na+-K+ ATPase -- Sarcolemmal Ca2+-transport -- Sarcoplasmic reticular Ca2+-transport -- Intracellular Ca2+-homeostasis -- Mitochondrial function -- Contractile proteins -- β-adrenoceptor mechanisms -- Protein kinases and signal transduction -- Regulation of phopholipases -- Endothelin defects and cardiac dysfunction -- Metabolic changes in smooth muscles -- Metabolic defects in skeletal muscles -- Metabolic defects in brain -- Role of microangiopathy in heart dysfunction -- Role of nephropathy in heart dysfunction -- Prevention of diabetic-induced cardiac dysfunction -- Molecular targets for the therapy of diabetic cardiomyopathy. |
Record Nr. | UNINA-9910298347803321 |
New York : , : Springer, , 2014 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The Renin Angiotensin System in Cancer, Lung, Liver and Infectious Diseases / / edited by Sukhwinder K. Bhullar, Paramjit S. Tappia, Naranjan S. Dhalla |
Edizione | [1st ed. 2023.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
Descrizione fisica | 1 online resource (499 pages) |
Disciplina |
615.36
612.17 |
Collana | Advances in Biochemistry in Health and Disease |
Soggetto topico |
Medicine - Research
Biology - Research Human physiology Cancer Cancer - Treatment Virology Therapeutics Biomedical Research Human Physiology Cancer Biology Cancer Therapy |
ISBN | 3-031-23621-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | 1. Implications of renin-angiotensin system in health and disease -- 2. Renin angiotensin system and aging -- 3. The interplay of the renin-angiotensin system and solid organ transplantation -- 4. Correlation between renin angiotensin system and infectious disease -- 5. Emerging contributions of endocrine pathophysiology in virus-related infectious disease -- 6. Understanding the renin-angiotensin system in coronavirus disease 2019 -- 7. Metabolomics approach in differentiating RAS responses in ARDS (Acute respiratory distress syndrome) and SAR-CoV-2 -- 8. A Comprehensive review of the impact of the renin angiotensin system in the liver, lung, infectious diseases and cancers -- 9. Application of biosensors for monitoring changes in renin angiotensin system (RAS) in cancers and lung diseases -- 10. Bioinformatics study on renin angiotensin in lung, and liver cancer using plant-based extracts -- 11. Role of renin-angiotensin system in the pathogenesis and progression of non-alcoholic fatty liver -- 12. The classical and nonclassical renin-angiotensin-aldosterone system in liver cirrhosis -- 13. Renin-angiotensin-aldosterone system role in organ fibrosis -- 14. Role of renin angiotensin-aldosterone system in kidney homeostasis -- 15. Renin-angiotensin system in chronic kidney disease: Implications in stroke outcome -- 16. The renin-angiotensin system and cancer -- 17. Renin-angiotensin system and cancer: From laboratory to clinics -- 18. Role of renin-angiotensin system in cancer cachexia -- 19. Renin angiotensin system activity in different cancers: Mechanistic insight and preclinical studies -- 20. The new dimension of the renin-angiotensin system in the hallmarks of cancer -- 21. Renin-angiotensin system in hematological malignancies -- 22. Renin angiotensin system (RAS): The common thread between cancer and heart failure -- 23. Renin-angiotensin system: a potential therapeutic target for colorectal cancer -- 24. Anticancer role of natural phenolic acids by targeting angiotensin-converting enzyme (ACE) -- 25. Angiotensin-(1-7): A Prospective Cancer Therapeutic. |
Record Nr. | UNINA-9910682569503321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The Renin Angiotensin System in Cardiovascular Disease / / edited by Naranjan S. Dhalla, Sukhwinder K. Bhullar, Anureet K. Shah |
Edizione | [1st ed. 2023.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
Descrizione fisica | 1 online resource (453 pages) |
Disciplina | 616.980214 |
Collana | Advances in Biochemistry in Health and Disease |
Soggetto topico |
Medicine - Research
Biology - Research Cardiovascular system Physiology Cardiology Clinical biochemistry Biomedical Research Cardiovascular Physiology Medical Biochemistry |
ISBN | 3-031-14952-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Past, present and future perspectives of renin angiotensin system -- Biochemical pathways of renin angiotensin system -- Structure-function relationships of angiotensin II receptors -- Signal transduction mechanism of angiotensin II -- Renin angiotensin system: Pathophysiology and clinical implications in cardiovascular disease COVID-19 infection -- Angiotensin II and the pathogenesis of hypertension -- Signaling transduction of angiotensin II in hypertension -- Role of angiotensin II type 1 receptors in vascular remodeling in hypertension -- Molecular and cellular mechanisms of renin-angiotensin system in hypertension -- Tissue renin-angiotensin system and risks in hypertension -- Oxidative stress and angiotensin II-induced hypertension -- Angiotensin II: inflammatory system disorder and hypertension -- Therapeutic approaches for angiotensin receptor blockers in hypertension -- Renin-angiotensin systems: A pivotal role in the development of atherosclerosis -- Angiotensin II induced intracellular signaling pathways in pathogenesis of atherosclerosis -- Cellular and molecular mechanisms of Ang II: Contribution to atherosclerotic plaque vulnerability -- Role of angiotensin II, nitric oxide and reactive oxygen species in atherosclerosis -- The renin-angiotensin system and inflammatory processes in atherosclerotic lesion formation -- Role of renin-angiotensin system in alterations in blood lipids and gene expression in atherogenesis -- Effects of angiotensin-converting enzyme and receptors in atherosclerosis -- Effects of angiotensin II on cardiac arrhythmia and signal transduction -- Angiotensin II induced oxidative stress contribute to ventricular arrhythmias -- Modulation of renin angiotensin system: Beneficial effect on ventricular arrhythmias -- ACE inhibitor and ventricular arrhythmia in ischemic heart disease -- The renin-angiotensin system modulators and cardiac arrhythmias -- Angiotensin receptor blockers in the treatment of arrhythmias -- Angiotensin II induced cardiac hypertrophy and heart failure -- Renin-angiotensin system: Role in cardiac remodeling and subcellular defects in heart failure -- Renin-angiotensin system: Molecular and cellular mechanisms in heart failure -- Role of angiotensin II receptor mRNA expression in heart failure -- Renin angiotensin system: Mitochondrial dysfunction in the progression of heart failure -- Angiotensin II type 1 receptor: Genetic polymorphisms and heart failure -- Angiotensin converting enzyme 2 and angiotensin metabolism in heart failure -- Cellular and molecular mechanisms of renin-angiotensin system blockade in heart failure: An update -- Angiotensin II receptor antagonists: Modulation of the extracellular matrix regulatory system in heart failure. |
Record Nr. | UNINA-9910637718403321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Sex differences in heart disease / / Bohuslav Ostadal and Naranjan S. Dhalla (editors) |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2020] |
Descrizione fisica | 1 online resource (XVI, 284 p. 47 illus., 15 illus. in color.) |
Disciplina | 573.1 |
Collana | Advances in Biochemistry in Health and Disease |
Soggetto topico | Cardiovascular Biology |
ISBN | 3-030-58677-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | The role of sex in cardiac function and disease -- Sex based differences in cardiac ischemic injury and reperfusion -- Sex differences in myocardial infarct size -- Sex differences in the susceptibility to ischemic injury – the role of calcium loading and adrenergic stimulation -- Sex and obesity and myocardial tolerance to ischemia -- Effect of female sex on rat ventricular myocytes exposed to stimulated ischemia -- Cardioprotection in females -- Sex differences in Cardioprotection ischemia reperfusion injury -- Sex and ischemic preconditioning -- Postconditioning and female heart -- Prenatal hypoxia and sex-dependent increase in heart susceptibility in adults -- Sex and cardiovascular system -- Sex differences in coronary heart disease -- Sex differences in the management of non-ST-elevation acute coronary syndrome -- Sex specific aspects of coronary heart disease risk factors -- Sex differences in patients with ischemic heart failure undergoing surgical treatment -- Woman and the management of acute coronary syndrome -- Sex differences and heart hypertrophy and failure -- Sex differences among patients with acute coronary syndrome undergoing PTCA -- Sex differences and atherosclerosis -- Estrogen and cardiovascular system -- Estrogen signaling and cardiovascular disease -- A novel estrogen receptor GPER and its role in the protection against ischemia/reperfusion injury -- Sexual hormones: effects on mitochondrial activity after ischemia/reperfusion injury -- Progesterone and ischemia/reperfusion injury -- Testosteron and myocardial infarction -- Postmenopausal hormone therapy: risks and benefits -- Molecular and cellular basis of cardiovascular sex differences -- Mitochondria – a target for sex differences in cardiac pathology -- Sex differences in the sensitivity of cardiac mitochondrial permeability transition pore to calcium load -- Sex differences in mitochondrial biogenesis -- Sexual dimorphism in the expression of mitochondria-related genes in rat heart -- Sex differences in mitochondrial antioxidant gene expression -- Sex differences in the regulation of mitochondrial subpopulations -- Sex specificities in Ca handling in cardiac mitochondria -- The influence of exercise and sex on mitochondrial metabolism and ultrastructure -- Sex differences in the phosphorylation of mitochondrial proteins – effect on cardioprotection -- Sex – specific proteomic alterations in mitochondrial pathways. |
Record Nr. | UNINA-9910426054603321 |
Cham, Switzerland : , : Springer, , [2020] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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