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Biochemistry of Cardiovascular Dysfunction in Obesity / / edited by Paramjit S. Tappia, Sukhwinder K. Bhullar, Naranjan S. Dhalla
| Biochemistry of Cardiovascular Dysfunction in Obesity / / edited by Paramjit S. Tappia, Sukhwinder K. Bhullar, Naranjan S. Dhalla |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
| Descrizione fisica | 1 online resource (XV, 401 p. 55 illus., 48 illus. in color.) |
| Disciplina | 616.1 |
| Collana | Advances in Biochemistry in Health and Disease |
| Soggetto topico |
Human physiology
Human Physiology |
| ISBN | 3-030-47336-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Biochemistry of cardiovascular dysfunction in obesity -- Vascular mechanisms linking RAAS components to obesity-associated hypertension -- Mechanisms of obesity-induced hypertension in adolescents -- Role of the sympathetic nervous system in obesity-induced hypertension -- Sex differences in the mechanisms associated with obesity-induced hypertension -- Leptin as a mediator of obesity-induced hypertension -- Endothelial dysfunction in obesity -- Neurohormonal regulation of sympathoexcitation and hypertension in obesity -- Role of obesity in hypertension in children -- Small for gestational age and obesity associated co-morbidities -- Obesity-Related Hypertension in Children -- The relationship between obesity and hypertension -- Hypertension in Obesity and the Impact of Weight Loss -- Parallels in the Evolution of Obesity and Hypertension -- Obesity and hypertension -- The microcirculation: a key player in obesity-associated cardiovascular disease -- Sex Differences in Leptin Control of Cardiovascular Function in Health and Metabolic Diseases -- Sex differences in the role of leptin and coronary heart disease -- Differential effect of subcutaneous abdominal and visceral adipose tissue on cardiometabolic risk -- Sex differences in lipid and lipoprotein metabolism -- Sex differences in the mechanisms of obesity-induced hypertension -- Impaired cardiac function in obese individuals -- Role of Vitamin D deficiency in cardiac function -- Obesity in advanced heart failure -- Cardiovascular morbidity and mortality associated with obesity -- Risk of overweight with the development of heart failure -- Obesity and heart failure -- Obesity phenotypes and their paradoxical association with cardiovascular diseases -- Mechanisms of heart failure with preserved ejection fraction in obesity -- Obesity and cardiovascular diseases -- Obesity and Heart Failure: Possible mechanisms of the Obesity Paradox -- Prognosis of morbid obesity patients with advanced heart failure -- BMI as a risk factor for cardiovasculardisease -- Relationship between BMI and cardiovascular outcomes in diabetic patients -- Cardiometabolic risk in obese children -- Gender related differences in obesity associated cardiovascular complications -- Understanding the mechanisms and clinical significance of the obesity paradox -- Advances in understanding gender difference in cardiometabolic disease risk -- Cardiovascular and Metabolic Complications – Diagnosis and Management in Obese Children -- Obesity and Ventricular Repolarization. |
| Record Nr. | UNINA-9910424634603321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomedical Translational Research : Drug Design and Discovery / / edited by R.C. Sobti, Naranjan S. Dhalla
| Biomedical Translational Research : Drug Design and Discovery / / edited by R.C. Sobti, Naranjan S. Dhalla |
| Edizione | [1st ed. 2022.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2022 |
| Descrizione fisica | 1 online resource (597 pages) |
| Disciplina | 610.28 |
| Soggetto topico |
Medicine - Research
Biology - Research Drugs - Design Pharmaceutical chemistry Genomics Bioinformatics Biomedical Research Structure-Based Drug Design Pharmaceutics Disseny de medicaments Enginyeria biomèdica |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 981-16-9232-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1. Emerging Technologies : Gateway to Understand Molecular Insight of Diseases, Newer Drugs, Their Design and Targeting -- Chapter 2. Polypharmacology: New Paradigms in Drug Development -- Chapter 3. Drug Repurposing in Biomedical Research : Benefits and Challenges -- Chapter 4. Computational Methods for Drug Repurposing -- Chapter 5. Genomic Approaches for Drug Repositioning -- Chapter 6. Organ-On-A- Chip: Novel in-Vitro Model For Drug Discovery -- Chapter 7. Precision Radiomolecular Oncology: Challenging the Classical Statistical Evidence Based Medicine -- Chapter 8. Drug Repositioning of the Phenylpiperazine Derivative Naftopidil in Prostate Cancer Treatment -- Chapter 9. Biomarker Based Drug Discovery and Reverse Translational Approach -- Chapter 10. Nanotechnology in Dentistry -- Chapter 11. Nanoparticles a Potential Breakthrough in Counteracting Multidrug-Resistant Bacterial Infections: A Holistic View on Underlying Mechanisms and Antibacterial Properties -- Chapter 12. Emerging Role of Cannabinoid System Modulators in Treatment of Cancer -- Chapter 13. Nanodrugs : A Futuristic Approach for Treating Nephrolithiasis -- Chapter 14. Lipo Dermaceuticals : Technological Transformation -- Chapter 15. The Importance of Drug Dose Adjustment in Elderly Patients with Special Considerations for Patients on Diverse Co-Medications and Antidepressants -- Chapter 16. Role of Microfluidics and Nano Fluidics in Managing CAD -- Chapter 17. Targeted Gene Delivery Through Magnetofection: The New Face of Medicine -- Chapter 18. Qbd-Steered Systematic Development of Drug Delivery Nanoconstructs : Vital Precepts, Retrospect and Prospects -- Chapter 19. Nanoemulsions: A Potential Advanced Nanocarrier Platform for Herbal Drug Delivery -- Chapter 20. Sirna Encapsulated Nanoparticles for Targeting Dorsal Root Ganglion (Drg) in Diabetic Neuropathic Pain -- Chapter 21. EGFR Targeted Quinazoline Clubbed Heterocycles as Anti-Cancer Agents. Chapter 22. Therapeutic Human Monoclonal Antibodies -- Chapter 23. Hydroxyapatites and Their Biomedical Applications -- Chapter 24. Recent Progress in Applications of Magnetic Nanoparticles in Medicine: A Review -- Chapter 25. Chimeric Antigen Receptor T-Cell Therapy: A Cutting Edge Therapy for Multiple Myeloma -- Chapter 26. Nanoparticles-Associated Lipopeptides: A New Class of Antimicrobials -- Chapter 27. Antimicrobial Applications of Engineered Metal-Based Nanomaterials -- Chapter 28. Strengthening Immunity-Ayurveda & Medicinal Plants -- Chapter 29. The Pathophysiology of Liver Disorders and Pharmacotherapy Options with Special Reference to Traditional Herbal Medicines: A Comprehensive Review -- Chapter 30. Polymeric Vehicles for Controlled Delivery of Ayurvedic Drugs for Wound Management. |
| Record Nr. | UNINA-9910585974703321 |
| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cardiac Energy Metabolism in Health and Disease / / edited by Gary D. Lopaschuk, Naranjan S. Dhalla
| Cardiac Energy Metabolism in Health and Disease / / edited by Gary D. Lopaschuk, Naranjan S. Dhalla |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (301 p.) |
| Disciplina |
612.173
616.1205 |
| Collana | Advances in Biochemistry in Health and Disease |
| Soggetto topico |
Biochemistry
Bioinformatics Cardiology Computational and Systems Biology |
| ISBN | 1-4939-1227-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part 1. Control of Energy Metabolism -- 1. A Primer on Carbohydrate Metabolism in the Heart -- 2. Lipoproteins: A Source of Cardiac Lipids -- 3. Role of Lipoprotein Lipase in Fatty Acid Delivery to the Heart -- 4. Control of Myocardial Fatty Acid Uptake -- 5. Cardiac Energy Metabolism in Heart Failure Associated with Obesity and Diabetes -- 6. Transcriptional Control of Mitochondrial Biogenesis and Maturation -- 7. Relationship between Substrate Metabolism and Cardiac Efficiency -- 8. Acetylation in the Control of Mitochondrial Metabolism and Integrity -- Part 2. Alteration in Energy Metabolism -- 9. Adrenergic Control of Cardiac Fatty Acid Oxidation in Diabetes -- 10. The Myocardial Creatine Kinase System in the Normal, Ischaemic and Failing Heart -- 11. Fuel Metabolism Plasticity in Pathological Cardiac Hypertrophy and Failure -- 12. Defects in Mitochondrial Oxidative Phosphorylation in Hearts Subjected to Ischemia-Reperfusion Injury -- 13. The Role of AMPK in the Control of Cardiac Hypertrophy -- 14. The Role of Incomplete Fatty Acid Oxidation in the Development of Cardiac Insulin Resistance -- Part 3. Optimization of Energy Metabolism -- 15. Metabolic Therapy for the Ischemic Heart -- 16. Inhibition of Fatty Acid Oxidation to Treat Heart Failure in Patients -- 17. Cardiac Metabolic Protection for the Newborn Heart -- 18. Targeting Transcriptional Control of Fatty Acid Oxidation to Treat Heart Disease. |
| Record Nr. | UNINA-9910298350603321 |
| New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cellular and Biochemical Mechanisms of Obesity / / edited by Paramjit S. Tappia, Bram Ramjiawan, Naranjan S. Dhalla
| Cellular and Biochemical Mechanisms of Obesity / / edited by Paramjit S. Tappia, Bram Ramjiawan, Naranjan S. Dhalla |
| Edizione | [1st ed. 2021.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 |
| Descrizione fisica | 1 online resource (420 pages) |
| Disciplina | 574.192 |
| Collana | Advances in Biochemistry in Health and Disease |
| Soggetto topico |
Human physiology
Human Physiology Obesitat Trastorns del metabolisme |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-84763-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cellular and biochemical mechanisms of obesity -- The role of inflammation in obesity -- Hypothalamic inflammation and malfunctioning glia in the pathophysiology of obesity -- The role of the inflammasome in obesity -- Adipose tissue macrophages and their polarization in health and obesity -- Adolescent Obesity and Insulin Resistance: Roles of Ectopic Fat Accumulation and Adipose Inflammation -- The interplay between adipocytes and immune system cells in the pathophysiology of obesity -- Neuropeptides in Obesity and Metabolic Disease -- Adiposity and the Role of Neuroendocrine Hormones in Energy Balance -- Obesity in menopause -- Ovarian hormones and obesity -- The role of tissue-specific glucocorticoids in central obesity -- Thyroid function in obesity -- Glucocorticoid hormones: cause or cure for obesity -- Obesity: An overview of possible role(s) of gut hormones, lipid sensing and gut microbiota -- Recent advances in leptin and obesity -- Pathophysiology of obesity due to neurohormonal dysregulation and autophagy -- The Role of the Autonomic Nervous System in the Pathophysiology of Obesity -- Disturbance of neuronal signals in the pathophysiology of obesity -- The sympathetic neuro-adipose connection and the control of body weight -- Sympathetic activation in obesity -- Obesity-associated sympathetic overactivity in children and adolescents: the role of catecholamine resistance in lipid metabolism -- Relevance of Sympathetic Nervous System Activation in Obesity and Metabolic Syndrome -- Should the sympathetic nervous system be a target to improve obesity? -- Metabolic Syndrome and Oxidative Stress: A Complex Relationship -- The role of oxidative stress in the pathogenesis of obesity -- How effective are antioxidant supplements in obesity -- Oxidative stress in obesity: a critical component in human diseases -- Cellular mechanisms involved in the pathophysiology of obesity during oxidative stress -- Oxidative stress and metabolic pathologies: from an adipocentric point of view -- Oxidative stress contributes to the pathogenesis of obesity -- The genetics of oxidative stress in obesity -- Increased oxidative stress is associated with adipocyte fat accumulation -- The vicious cycle of oxidative stress and obesity -- GPCR-Mediated Signaling of Metabolites in the pathophysiology of obesity -- Ceramide signaling in obesity -- The role of the triggering receptor in the pathophysiology of obesity -- The AMPK pathway in the development of obesity -- Interleukin-1 superfamily: Divergent roles in obesity -- Ghrelin Receptor Mutations and Human Obesity -- Sirtuin 1 deacetylase: a key regulator of hepatic lipid metabolism -- JAK/STAT signaling pathway in the development of obesity -- SIRT1 and SIRT3 as mediators for the development of obesity -- Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity -- Interplay between Obesity and cGMP Signaling in adipose tissue. |
| Record Nr. | UNINA-9910513582303321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Diabetic Cardiomyopathy : Biochemical and Molecular Mechanisms / / edited by Belma Turan, Naranjan S. Dhalla
| Diabetic Cardiomyopathy : Biochemical and Molecular Mechanisms / / edited by Belma Turan, Naranjan S. Dhalla |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (xix, 416 pages) : illustrations (some color) |
| Disciplina | 616.1071 |
| Collana | Advances in Biochemistry in Health and Disease |
| Soggetto topico |
Proteins
Diseases Cardiology Human physiology Biological transport Cell membranes Clinical biochemistry Protein Biochemistry Human Physiology Membrane Trafficking Medical Biochemistry |
| ISBN |
9781461493174
146149317X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cardiac defects in diabetes -- Hormonal imbalance and neuropathy -- Role of oxidative stress -- Role of cation channel defects -- Abnormalities in glucose transport -- Fatty acid utilization -- Sarcolemmal Na+-K+ ATPase -- Sarcolemmal Ca2+-transport -- Sarcoplasmic reticular Ca2+-transport -- Intracellular Ca2+-homeostasis -- Mitochondrial function -- Contractile proteins -- β-adrenoceptor mechanisms -- Protein kinases and signal transduction -- Regulation of phopholipases -- Endothelin defects and cardiac dysfunction -- Metabolic changes in smooth muscles -- Metabolic defects in skeletal muscles -- Metabolic defects in brain -- Role of microangiopathy in heart dysfunction -- Role of nephropathy in heart dysfunction -- Prevention of diabetic-induced cardiac dysfunction -- Molecular targets for the therapy of diabetic cardiomyopathy. |
| Record Nr. | UNINA-9910298347803321 |
| New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Functional biochemistry of metallic elements / / Naranjan S. Dhalla, Paramjit S. Tappia, Anureet K. Shah, editors
| Functional biochemistry of metallic elements / / Naranjan S. Dhalla, Paramjit S. Tappia, Anureet K. Shah, editors |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2026 |
| Descrizione fisica | 1 online resource (592 pages) : illustrations (some color) |
| Disciplina | 572 |
| Collana | Advances in Biochemistry in Health and Disease |
| Soggetto topico |
Metals - Physiological effect
Metals - Therapeutic use Biochemistry Metal ions Clinical biochemistry Metal Ions Medical Biochemistry |
| ISBN |
3-032-14445-0
9783032144454 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I. Trace Elements in Health and Disease -- Chapter 1. Modulation of Trace Elements in Pregnant Women and its Clinical Importance for Fetal Development -- Chapter 2. Trace Elements as Molecular Orchestrators of Health and Disease: A Biochemical and Pathophysiological Perspective -- Chapter 3. Trace Minerals (Fe, Zn, Cr, Cu, Se, V, Mn, Mo, Co) in Human Health and Disease -- Chapter 4. Sources and Role of Trace Elements in Nutrition -- Chapter 5. The Neuroprotective Role of Micronutrients: A Systematic Review of Preclinical and Clinical Studies on Antioxidant Vitamins, Essential Minerals, and Trace Elements in Managing Neurodegenerative Diseases -- Chapter 6. Chromium in the Prevention of Diabetes-induced Cardiovascular and Renal Disorders: Where do We Stand Now? -- Chapter 7. The Role of Antioxidant-associated Trace Elements in the Development Diabetic Cardiomyopathy -- Chapter 8. Selenium and the Heart: Molecular Insights into Cardioprotection – A Review -- Chapter 9. The Role of Cadmium in the Development and Progression of Liver Cancer -- Chapter 10. Functional Biochemistry of Trace Elements in Cancer: Mechanisms, Biomarkers, and Therapeutic Potentials -- Part II. Heavy Metals and Major Minerals -- Chapter 11. Heavy Metals for Treating Disease and Maintaining Health -- Chapter 12. Role of Micronutrients in the Treatment of Metal/ Metalloid Toxicity: Mechanisms and Therapeutic Potential -- Chapter 13. Development of Hypertension in Response to Chronic Exposure to Mercury -- Chapter 14. Occupational Lead Exposure and its Association with Reproductive Dysfunctions in Both Genders -- Chapter 15. Essential and Toxic: The Dual Nature of Heavy Metals in Human Physiology -- Chapter 16. Functional Biochemistry of Iron and its Cardio-pulmonary Impact -- Chapter 17. Iron Metabolism and Its Role in Anemia -- Chapter 18. The Involvement of Copper Deficiency in the Pathogenesis of Non-alcoholic Fatty Liver Disease -- Chapter 19. Major Minerals: Cardiometabolic Benefits and their Role in Promoting Healthy Aging -- Chapter 20. Major Minerals (Na, K, Ca, Mg, P) in Physiological Function and Disease -- Chapter 21. Sodium Homeostasis and Roles of Sodium-Dependent Transport in Health. |
| Record Nr. | UNINA-9911114560503321 |
| Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2026 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Modulation of Oxidative Stress in Heart Disease / / edited by Sajal Chakraborti, Naranjan S. Dhalla, Madhu Dikshit, Nirmal K. Ganguly
| Modulation of Oxidative Stress in Heart Disease / / edited by Sajal Chakraborti, Naranjan S. Dhalla, Madhu Dikshit, Nirmal K. Ganguly |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (XIII, 686 p. 114 illus., 100 illus. in color.) |
| Disciplina | 571.9453 |
| Soggetto topico |
Oxidative stress
Cardiovascular system Cardiology Cell physiology Biochemistry Biomedical engineering Oxidative Stress Cardiovascular Biology Cell Physiology Biochemistry, general Biomedical Engineering/Biotechnology Estrès (Psicologia) Malalties del cor |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 981-13-8946-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910373918403321 |
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oxidative Stress in Heart Diseases / / edited by Sajal Chakraborti, Naranjan S Dhalla, Nirmal K Ganguly, Madhu Dikshit
| Oxidative Stress in Heart Diseases / / edited by Sajal Chakraborti, Naranjan S Dhalla, Nirmal K Ganguly, Madhu Dikshit |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (XIII, 596 p. 66 illus.) |
| Disciplina | 571.6 |
| Soggetto topico |
Cytology
Cardiology Biochemistry Biomedical engineering Health promotion Cell physiology Cell Biology Biochemistry, general Biomedical Engineering/Biotechnology Health Promotion and Disease Prevention Cell Physiology Estrès oxidatiu Malalties del cor |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 981-13-8273-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | I. Role of Oxidative Stress in Heart Diseases -- 1. J.L Johnson. Laboratory of cardiovascular pathology, School of Clinical Sciences, University of Bristol, Bristol. UK -- 2. M.A.Srivastava, Department of Physiology, McGill University, Canada -- 3. P. Balakumar. Pharmacology Unit, AIMST University, Semeling 08100 Bedong, Kedah Darul Aman, Malaysia -- 4. K. B Pasumarthi. Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada -- 5. B. Turan. Department of Biophysics, Ankara University, Faculty of Medicine, Ankara,Turkey -- 6. Z. Xie. Marshall Institute of Interdisciplinary Research, Marshall University, Huntington,WV, USA -- 7. T. L. Haas. Angiogenesis Research Group, School of Health Sciences, York University,Toronto, Canada -- 8. A. Kukol. School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK -- 9. N.S.Dhalla, Cardiovascular Research Institute, University of Manitoba, Winnipeg, Canada -- 10. A.K.Srivastava. Cell Signalling laboratory, McGill University, Canada -- 11. S.Chakraborti, University of Kalyani, Kalyani 741235, West Bengal, India -- 12. S.Goswami, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India -- 13. C.C.Kartha, Rajiv Gandhi Institute of Biotechnology, Thiruvanatapuram, India -- 14. S.K.Malick, Department of Pharmacology. AIIMS, New Delhi, India -- 15. S.Chatterjee, Anna University, Chennai, India -- 16. N.Mahapatra, IIT-Madras, Chennai, India -- 17. R. Bhunya, Department of Biochemistry and Biophysicvs, University of kalyani, West Bengal, India -- 18. S.Nandi, North Est Hill University, Meghalaya, India -- 19. N.K.Ganguly, Sir gangaram Hospital, New Delhi -- 20. M.Dixit, CSIR-CDR, -Lucknow, India -- 21. A.D.Abell, University of Adelaide, Australia -- 22. Chava Kimchi Sarfaty, Centre for Biologics Evaluation and Research, Foodand Drug Administration, Bethesda, Maryland, USA -- 23. B. Furhman, Technion Faculty of Medicine and Ramban Medical Center, Hiafa, Israel -- 24. R.F.Gerlach, Department of Physiology, University of Sao Paulo, Brazil -- 25.T.L.Haas, School of Kinesiology and Health Sciences, York University, Toronto, Canada -- 26. B. Mittal, Department of Genetics. Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttap Pradesh, India -- 27. Richard Schulz, Department of Pedfiatrics, University of Alberta, Canada -- 28. Bodh J Jugdutt, Mackenzie Haeth Sciences Centre, Division of Cardiology, University of Alberta, Canada -- 29. Vibha Rani, Jaypee Institute of Information Technology, Noida, Uttar Pradesh, India -- 34. Veena Dhawan, Department of Experimental Medicine and Biotechnology,PGIMER,Chandigarh, India -- 30. Surekha Rani, Department of Genetics, Osmania University, Hyderabad, Telengana State, India. |
| Record Nr. | UNINA-9910373919303321 |
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pathophysiological Aspects of Proteases / / edited by Sajal Chakraborti, Naranjan S. Dhalla
| Pathophysiological Aspects of Proteases / / edited by Sajal Chakraborti, Naranjan S. Dhalla |
| Edizione | [1st ed.. 2017.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (XV, 671 p. 88 illus., 71 illus. in color.) |
| Disciplina | 612 |
| Soggetto topico |
Human physiology
Molecular biology Pharmaceutical technology Cancer - Research Human Physiology Molecular Medicine Pharmaceutical Sciences/Technology Cancer Research |
| ISBN | 981-10-6141-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Protease mediated viral infection -- Role of proteases in cancer pathology especially in breast cancer, as well as role of proteases as posible targets for drug development for cancer -- The multifunctional post-prolinedipeptidyl peptidase, DPP9, in EGF signaling, immunity and cancer biology -- Translating the knowledge of functional dynamics towards designing inhibitors of BACE1, a key aspartate protease in Alzheimer's disease -- Cysteine Dependent Aspartate Specific Proteases in Coronary Artery Disease -- Matrix metalloproteases: Potential role in Type 2 Diabetic Nephropathy -- Matrix-metalloproteinases in Breast Carcinoma, Immunohistology and Prognosis -- Matrix metalloproteinases in parasitic infections -- Role of proteases in cancer metastasis -- Proteolytic activation of kinase growth factors in the pathophysiology of cancer -- Involvement of m-Calpain in Colorectal Adenocarcinomas -- Proteases in Cancer: Potential Therapeutic Targets -- MMPs in Oral Squamous Cell Carcinoma -- Matrix metalloproteinase silencing: a therapeutic approach to treat cardiovascular pathology -- Proteases and Breast cancer -- Matrix metalloproteinases (MMPs) in cancer initiation and progression -- Neutrophil Serine protease in health and disease -- Proteases in disease pathology -- PAR1 mediated apoptosis and tumor regression of breast cancer cells by V. cholerae hemagglutinin protease -- Protein-protease interactions : an overview of the process from an ‘in silico’ perspective -- The functional relevance of Deubiquitinases in life and disease -- Physiological and pathological functions of mitochondrial proteases -- Proteases of parasitic helminths: their metabolic role in establishment of infection in the host -- Cysteine proteases of parasitic helminths -- Targeting proteases in urine for bladder cancer diagnosis. |
| Record Nr. | UNINA-9910253960203321 |
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Proteases in Human Diseases / / edited by Sajal Chakraborti, Tapati Chakraborti, Naranjan S. Dhalla
| Proteases in Human Diseases / / edited by Sajal Chakraborti, Tapati Chakraborti, Naranjan S. Dhalla |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (XVII, 513 p. 63 illus., 52 illus. in color.) |
| Disciplina | 612 |
| Soggetto topico |
Human physiology
Molecular biology Pharmaceutical technology Cancer - Research Human Physiology Molecular Medicine Pharmaceutical Sciences/Technology Cancer Research |
| ISBN |
9789811031618
9789811031625 (e-book) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Matrix metalloproteases in breast carcinoma, immunohistology and prognosis -- 2. Matrix metalloproteases in parasite infection -- 3. Cysteine cathepsins: In health and rheumatoid arthritis -- 4. Protective role of antiproteases in radiation induced damage -- 5. Role of proteases in the regulation of N-myristoyltransferase -- 6. Proteases in cancer: Potential therapeutic targets -- 7. MMPs in oral squamous cell carcinoma -- 8. Caspase regulatory mechanisms: Implications in pathogenesis and therapeutics -- 9. Physiological and pathological functions of mitochondrial proteases -- 10. Proteases of parasitic helminths: their metabolic role in establishment of infection in the host -- 11. Cysteine proteases of parasitic helminths -- 12. targeting proteases in urine for bladder cancer diagnosis -- 13. Intramembrane cleaving proteases (ICLiPs), particularly the gamma secretase protease and its role in neurodegeneration, cancer and innate immune signalling -- 14. Contribution of matrix metalloproteases in cardiovascular diseases -- 15. OPG/RANKL-protease axis in cardiometabolic diseases -- 16. Proteases and protease inhibitors in male reproduction -- 17. The role of MMP-2 and -9 in embryonic neural crest cells and their derivatives -- 18. Proteolytic ubiquitin like proteins -- 19. C.albicans aspartic proteases: role of these enzymes in degradation of crucial human host proteins at the place of infection and a possible implications of the protease action for propagation of infection. -- 20. MMPs in cancer -- 21. Pathophysiological roles played by proteases of Psedomonas aeruginosa: crucial multifunctional molecules involved in the host infection -- 22. Role of proteases on activating cell death pathways -- 23. varying faces of matrix metalloproteinases in cardiovascular diseases -- 24. kallikreins and kallikrein related peptides (KLKs) in health and disease -- 25. Endogenous proteases in tumoral progression. |
| Record Nr. | UNINA-9910253924403321 |
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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