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Biochemistry of cardiovascular dysfunction in obesity / / Paramjit S. Tappia, Sukhwinder K. Bhullar, Naranjan S. Dhalla, editors
Biochemistry of cardiovascular dysfunction in obesity / / Paramjit S. Tappia, Sukhwinder K. Bhullar, Naranjan S. Dhalla, editors
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2020]
Descrizione fisica 1 online resource (XV, 401 p. 55 illus., 48 illus. in color.)
Disciplina 616.1
Collana Advances in Biochemistry in Health and Disease
Soggetto topico Cardiovascular system - Diseases
ISBN 3-030-47336-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Biochemistry of cardiovascular dysfunction in obesity -- Vascular mechanisms linking RAAS components to obesity-associated hypertension -- Mechanisms of obesity-induced hypertension in adolescents -- Role of the sympathetic nervous system in obesity-induced hypertension -- Sex differences in the mechanisms associated with obesity-induced hypertension -- Leptin as a mediator of obesity-induced hypertension -- Endothelial dysfunction in obesity -- Neurohormonal regulation of sympathoexcitation and hypertension in obesity -- Role of obesity in hypertension in children -- Small for gestational age and obesity associated co-morbidities -- Obesity-Related Hypertension in Children -- The relationship between obesity and hypertension -- Hypertension in Obesity and the Impact of Weight Loss -- Parallels in the Evolution of Obesity and Hypertension -- Obesity and hypertension -- The microcirculation: a key player in obesity-associated cardiovascular disease -- Sex Differences in Leptin Control of Cardiovascular Function in Health and Metabolic Diseases -- Sex differences in the role of leptin and coronary heart disease -- Differential effect of subcutaneous abdominal and visceral adipose tissue on cardiometabolic risk -- Sex differences in lipid and lipoprotein metabolism -- Sex differences in the mechanisms of obesity-induced hypertension -- Impaired cardiac function in obese individuals -- Role of Vitamin D deficiency in cardiac function -- Obesity in advanced heart failure -- Cardiovascular morbidity and mortality associated with obesity -- Risk of overweight with the development of heart failure -- Obesity and heart failure -- Obesity phenotypes and their paradoxical association with cardiovascular diseases -- Mechanisms of heart failure with preserved ejection fraction in obesity -- Obesity and cardiovascular diseases -- Obesity and Heart Failure: Possible mechanisms of the Obesity Paradox -- Prognosis of morbid obesity patients with advanced heart failure -- BMI as a risk factor for cardiovascular disease -- Relationship between BMI and cardiovascular outcomes in diabetic patients -- Cardiometabolic risk in obese children -- Gender related differences in obesity associated cardiovascular complications -- Understanding the mechanisms and clinical significance of the obesity paradox -- Advances in understanding gender difference in cardiometabolic disease risk -- Cardiovascular and Metabolic Complications – Diagnosis and Management in Obese Children -- Obesity and Ventricular Repolarization.
Record Nr. UNINA-9910424634603321
Cham, Switzerland : , : Springer, , [2020]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Biomedical Translational Research : Drug Design and Discovery / / edited by R.C. Sobti, Naranjan S. Dhalla
Biomedical Translational Research : Drug Design and Discovery / / edited by R.C. Sobti, Naranjan S. Dhalla
Edizione [1st ed. 2022.]
Pubbl/distr/stampa Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2022
Descrizione fisica 1 online resource (597 pages)
Disciplina 610.28
Soggetto topico Medicine - Research
Biology - Research
Drugs - Design
Pharmaceutical chemistry
Genomics
Bioinformatics
Biomedical Research
Structure-Based Drug Design
Pharmaceutics
Disseny de medicaments
Enginyeria biomèdica
Soggetto genere / forma Llibres electrònics
ISBN 981-16-9232-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Chapter 1. Emerging Technologies : Gateway to Understand Molecular Insight of Diseases, Newer Drugs, Their Design and Targeting -- Chapter 2. Polypharmacology: New Paradigms in Drug Development -- Chapter 3. Drug Repurposing in Biomedical Research : Benefits and Challenges -- Chapter 4. Computational Methods for Drug Repurposing -- Chapter 5. Genomic Approaches for Drug Repositioning -- Chapter 6. Organ-On-A- Chip: Novel in-Vitro Model For Drug Discovery -- Chapter 7. Precision Radiomolecular Oncology: Challenging the Classical Statistical Evidence Based Medicine -- Chapter 8. Drug Repositioning of the Phenylpiperazine Derivative Naftopidil in Prostate Cancer Treatment -- Chapter 9. Biomarker Based Drug Discovery and Reverse Translational Approach -- Chapter 10. Nanotechnology in Dentistry -- Chapter 11. Nanoparticles a Potential Breakthrough in Counteracting Multidrug-Resistant Bacterial Infections: A Holistic View on Underlying Mechanisms and Antibacterial Properties -- Chapter 12. Emerging Role of Cannabinoid System Modulators in Treatment of Cancer -- Chapter 13. Nanodrugs : A Futuristic Approach for Treating Nephrolithiasis -- Chapter 14. Lipo Dermaceuticals : Technological Transformation -- Chapter 15. The Importance of Drug Dose Adjustment in Elderly Patients with Special Considerations for Patients on Diverse Co-Medications and Antidepressants -- Chapter 16. Role of Microfluidics and Nano Fluidics in Managing CAD -- Chapter 17. Targeted Gene Delivery Through Magnetofection: The New Face of Medicine -- Chapter 18. Qbd-Steered Systematic Development of Drug Delivery Nanoconstructs : Vital Precepts, Retrospect and Prospects -- Chapter 19. Nanoemulsions: A Potential Advanced Nanocarrier Platform for Herbal Drug Delivery -- Chapter 20. Sirna Encapsulated Nanoparticles for Targeting Dorsal Root Ganglion (Drg) in Diabetic Neuropathic Pain -- Chapter 21. EGFR Targeted Quinazoline Clubbed Heterocycles as Anti-Cancer Agents. Chapter 22. Therapeutic Human Monoclonal Antibodies -- Chapter 23. Hydroxyapatites and Their Biomedical Applications -- Chapter 24. Recent Progress in Applications of Magnetic Nanoparticles in Medicine: A Review -- Chapter 25. Chimeric Antigen Receptor T-Cell Therapy: A Cutting Edge Therapy for Multiple Myeloma -- Chapter 26. Nanoparticles-Associated Lipopeptides: A New Class of Antimicrobials -- Chapter 27. Antimicrobial Applications of Engineered Metal-Based Nanomaterials -- Chapter 28. Strengthening Immunity-Ayurveda & Medicinal Plants -- Chapter 29. The Pathophysiology of Liver Disorders and Pharmacotherapy Options with Special Reference to Traditional Herbal Medicines: A Comprehensive Review -- Chapter 30. Polymeric Vehicles for Controlled Delivery of Ayurvedic Drugs for Wound Management.
Record Nr. UNINA-9910585974703321
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2022
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Cellular and biochemical mechanisms of obesity / / Paramjit S. Tappia, Bram Ramjiawan and Naranjan S. Dhalla, editors
Cellular and biochemical mechanisms of obesity / / Paramjit S. Tappia, Bram Ramjiawan and Naranjan S. Dhalla, editors
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2021]
Descrizione fisica 1 online resource (420 pages)
Disciplina 574.192
Collana Advances in biochemistry in health and disease
Soggetto topico Biochemistry
Obesitat
Trastorns del metabolisme
Soggetto genere / forma Llibres electrònics
ISBN 3-030-84763-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910513582303321
Cham, Switzerland : , : Springer, , [2021]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Diabetic cardiomyopathy : biochemical and molecular mechanisms / / Belma Turan, Naranjan S. Dhalla, editors
Diabetic cardiomyopathy : biochemical and molecular mechanisms / / Belma Turan, Naranjan S. Dhalla, editors
Edizione [1st ed. 2014.]
Pubbl/distr/stampa New York : , : Springer, , 2014
Descrizione fisica 1 online resource (xix, 416 pages) : illustrations (some color)
Disciplina 616.1071
Collana Advances in Biochemistry in Health and Disease
Soggetto topico Myocardium - Diseases - Pathophysiology
Diabetes - Complications
Clinical biochemistry
ISBN 1-4614-9317-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cardiac defects in diabetes -- Hormonal imbalance and neuropathy -- Role of oxidative stress -- Role of cation channel defects -- Abnormalities in glucose transport -- Fatty acid utilization -- Sarcolemmal Na+-K+ ATPase -- Sarcolemmal Ca2+-transport -- Sarcoplasmic reticular Ca2+-transport -- Intracellular Ca2+-homeostasis -- Mitochondrial function -- Contractile proteins -- β-adrenoceptor mechanisms -- Protein kinases and signal transduction -- Regulation of phopholipases -- Endothelin defects and cardiac dysfunction -- Metabolic changes in smooth muscles -- Metabolic defects in skeletal muscles -- Metabolic defects in brain -- Role of microangiopathy in heart dysfunction -- Role of nephropathy in heart dysfunction -- Prevention of diabetic-induced cardiac dysfunction -- Molecular targets for the therapy of diabetic cardiomyopathy.
Record Nr. UNINA-9910298347803321
New York : , : Springer, , 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
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The Renin Angiotensin System in Cancer, Lung, Liver and Infectious Diseases / / edited by Sukhwinder K. Bhullar, Paramjit S. Tappia, Naranjan S. Dhalla
The Renin Angiotensin System in Cancer, Lung, Liver and Infectious Diseases / / edited by Sukhwinder K. Bhullar, Paramjit S. Tappia, Naranjan S. Dhalla
Edizione [1st ed. 2023.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023
Descrizione fisica 1 online resource (499 pages)
Disciplina 615.36
612.17
Collana Advances in Biochemistry in Health and Disease
Soggetto topico Medicine - Research
Biology - Research
Human physiology
Cancer
Cancer - Treatment
Virology
Therapeutics
Biomedical Research
Human Physiology
Cancer Biology
Cancer Therapy
ISBN 3-031-23621-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Implications of renin-angiotensin system in health and disease -- 2. Renin angiotensin system and aging -- 3. The interplay of the renin-angiotensin system and solid organ transplantation -- 4. Correlation between renin angiotensin system and infectious disease -- 5. Emerging contributions of endocrine pathophysiology in virus-related infectious disease -- 6. Understanding the renin-angiotensin system in coronavirus disease 2019 -- 7. Metabolomics approach in differentiating RAS responses in ARDS (Acute respiratory distress syndrome) and SAR-CoV-2 -- 8. A Comprehensive review of the impact of the renin angiotensin system in the liver, lung, infectious diseases and cancers -- 9. Application of biosensors for monitoring changes in renin angiotensin system (RAS) in cancers and lung diseases -- 10. Bioinformatics study on renin angiotensin in lung, and liver cancer using plant-based extracts -- 11. Role of renin-angiotensin system in the pathogenesis and progression of non-alcoholic fatty liver -- 12. The classical and nonclassical renin-angiotensin-aldosterone system in liver cirrhosis -- 13. Renin-angiotensin-aldosterone system role in organ fibrosis -- 14. Role of renin angiotensin-aldosterone system in kidney homeostasis -- 15. Renin-angiotensin system in chronic kidney disease: Implications in stroke outcome -- 16. The renin-angiotensin system and cancer -- 17. Renin-angiotensin system and cancer: From laboratory to clinics -- 18. Role of renin-angiotensin system in cancer cachexia -- 19. Renin angiotensin system activity in different cancers: Mechanistic insight and preclinical studies -- 20. The new dimension of the renin-angiotensin system in the hallmarks of cancer -- 21. Renin-angiotensin system in hematological malignancies -- 22. Renin angiotensin system (RAS): The common thread between cancer and heart failure -- 23. Renin-angiotensin system: a potential therapeutic target for colorectal cancer -- 24. Anticancer role of natural phenolic acids by targeting angiotensin-converting enzyme (ACE) -- 25. Angiotensin-(1-7): A Prospective Cancer Therapeutic.
Record Nr. UNINA-9910682569503321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023
Materiale a stampa
Lo trovi qui: Univ. Federico II
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The Renin Angiotensin System in Cardiovascular Disease / / edited by Naranjan S. Dhalla, Sukhwinder K. Bhullar, Anureet K. Shah
The Renin Angiotensin System in Cardiovascular Disease / / edited by Naranjan S. Dhalla, Sukhwinder K. Bhullar, Anureet K. Shah
Edizione [1st ed. 2023.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023
Descrizione fisica 1 online resource (453 pages)
Disciplina 616.980214
Collana Advances in Biochemistry in Health and Disease
Soggetto topico Medicine - Research
Biology - Research
Cardiovascular system
Physiology
Cardiology
Clinical biochemistry
Biomedical Research
Cardiovascular Physiology
Medical Biochemistry
ISBN 3-031-14952-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Past, present and future perspectives of renin angiotensin system -- Biochemical pathways of renin angiotensin system -- Structure-function relationships of angiotensin II receptors -- Signal transduction mechanism of angiotensin II -- Renin angiotensin system: Pathophysiology and clinical implications in cardiovascular disease COVID-19 infection -- Angiotensin II and the pathogenesis of hypertension -- Signaling transduction of angiotensin II in hypertension -- Role of angiotensin II type 1 receptors in vascular remodeling in hypertension -- Molecular and cellular mechanisms of renin-angiotensin system in hypertension -- Tissue renin-angiotensin system and risks in hypertension -- Oxidative stress and angiotensin II-induced hypertension -- Angiotensin II: inflammatory system disorder and hypertension -- Therapeutic approaches for angiotensin receptor blockers in hypertension -- Renin-angiotensin systems: A pivotal role in the development of atherosclerosis -- Angiotensin II induced intracellular signaling pathways in pathogenesis of atherosclerosis -- Cellular and molecular mechanisms of Ang II: Contribution to atherosclerotic plaque vulnerability -- Role of angiotensin II, nitric oxide and reactive oxygen species in atherosclerosis -- The renin-angiotensin system and inflammatory processes in atherosclerotic lesion formation -- Role of renin-angiotensin system in alterations in blood lipids and gene expression in atherogenesis -- Effects of angiotensin-converting enzyme and receptors in atherosclerosis -- Effects of angiotensin II on cardiac arrhythmia and signal transduction -- Angiotensin II induced oxidative stress contribute to ventricular arrhythmias -- Modulation of renin angiotensin system: Beneficial effect on ventricular arrhythmias -- ACE inhibitor and ventricular arrhythmia in ischemic heart disease -- The renin-angiotensin system modulators and cardiac arrhythmias -- Angiotensin receptor blockers in the treatment of arrhythmias -- Angiotensin II induced cardiac hypertrophy and heart failure -- Renin-angiotensin system: Role in cardiac remodeling and subcellular defects in heart failure -- Renin-angiotensin system: Molecular and cellular mechanisms in heart failure -- Role of angiotensin II receptor mRNA expression in heart failure -- Renin angiotensin system: Mitochondrial dysfunction in the progression of heart failure -- Angiotensin II type 1 receptor: Genetic polymorphisms and heart failure -- Angiotensin converting enzyme 2 and angiotensin metabolism in heart failure -- Cellular and molecular mechanisms of renin-angiotensin system blockade in heart failure: An update -- Angiotensin II receptor antagonists: Modulation of the extracellular matrix regulatory system in heart failure.
Record Nr. UNINA-9910637718403321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Sex differences in heart disease / / Bohuslav Ostadal and Naranjan S. Dhalla (editors)
Sex differences in heart disease / / Bohuslav Ostadal and Naranjan S. Dhalla (editors)
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2020]
Descrizione fisica 1 online resource (XVI, 284 p. 47 illus., 15 illus. in color.)
Disciplina 573.1
Collana Advances in Biochemistry in Health and Disease
Soggetto topico Cardiovascular Biology
ISBN 3-030-58677-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto The role of sex in cardiac function and disease -- Sex based differences in cardiac ischemic injury and reperfusion -- Sex differences in myocardial infarct size -- Sex differences in the susceptibility to ischemic injury – the role of calcium loading and adrenergic stimulation -- Sex and obesity and myocardial tolerance to ischemia -- Effect of female sex on rat ventricular myocytes exposed to stimulated ischemia -- Cardioprotection in females -- Sex differences in Cardioprotection ischemia reperfusion injury -- Sex and ischemic preconditioning -- Postconditioning and female heart -- Prenatal hypoxia and sex-dependent increase in heart susceptibility in adults -- Sex and cardiovascular system -- Sex differences in coronary heart disease -- Sex differences in the management of non-ST-elevation acute coronary syndrome -- Sex specific aspects of coronary heart disease risk factors -- Sex differences in patients with ischemic heart failure undergoing surgical treatment -- Woman and the management of acute coronary syndrome -- Sex differences and heart hypertrophy and failure -- Sex differences among patients with acute coronary syndrome undergoing PTCA -- Sex differences and atherosclerosis -- Estrogen and cardiovascular system -- Estrogen signaling and cardiovascular disease -- A novel estrogen receptor GPER and its role in the protection against ischemia/reperfusion injury -- Sexual hormones: effects on mitochondrial activity after ischemia/reperfusion injury -- Progesterone and ischemia/reperfusion injury -- Testosteron and myocardial infarction -- Postmenopausal hormone therapy: risks and benefits -- Molecular and cellular basis of cardiovascular sex differences -- Mitochondria – a target for sex differences in cardiac pathology -- Sex differences in the sensitivity of cardiac mitochondrial permeability transition pore to calcium load -- Sex differences in mitochondrial biogenesis -- Sexual dimorphism in the expression of mitochondria-related genes in rat heart -- Sex differences in mitochondrial antioxidant gene expression -- Sex differences in the regulation of mitochondrial subpopulations -- Sex specificities in Ca handling in cardiac mitochondria -- The influence of exercise and sex on mitochondrial metabolism and ultrastructure -- Sex differences in the phosphorylation of mitochondrial proteins – effect on cardioprotection -- Sex – specific proteomic alterations in mitochondrial pathways.
Record Nr. UNINA-9910426054603321
Cham, Switzerland : , : Springer, , [2020]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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