Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Neuroinflammation : new insights into beneficial and detrimental functions / / edited by Samuel David
| Neuroinflammation : new insights into beneficial and detrimental functions / / edited by Samuel David |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, , 2015 |
| Descrizione fisica | 1 online resource (322 p.) |
| Disciplina | 616.8/0479 |
| Soggetto topico |
Central nervous system - Diseases
Central nervous system - Diseases - Immunological aspects |
| ISBN |
1-118-73277-4
1-118-73274-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Title Page; Copyright; Contents; Contributors; Preface; Part I Introduction; Chapter 1 Immune Response in the Human Central Nervous System in Multiple Sclerosis and Stroke; Introduction; The Concept of Neuroinflammation; Basic Principles of Immune Surveillance and Inflammation by Adaptive Immune Responses; Inflammation in the Central Nervous System of Patients with Multiple Sclerosis; Inflammation in Stroke Lesions; Microglia Activation and Macrophage Response; Granulocyte Infiltration; Conclusions; References
Chapter 2 In Vivo Imaging of Glial and Immune Cell Responses in Central Nervous System Injury and DiseaseIntroduction; Intravital Microscopy in the CNS and Its Challenges; In Vivo Imaging of the CNS Following Sterile Injury; In Vivo Imaging of the CNS in Disorders with an Inflammatory Component; Conclusion; Acknowledgments; References; Part II Detrimental Aspects of Inflammation; Chapter 3 Roles of CD4 and CD8 T Lymphocytes in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis; Introduction; T Lymphocytes: Central Immune Cells; Autoreactive T Lymphocytes From Peripheral Activation to CNS ExtravasationRole of CD4 T Lymphocytes in MS and EAE: Th1 versus Th17; Role of CD8 T Lymphocytes in MS and EAE; Regulatory T Lymphocytes in MS and EAE; Conclusions; Acknowledgments; References; Chapter 4 Microglia and Macrophage Responses and Their Role after Spinal Cord Injury; Introduction; Microglial Responses to Injury; Interactions between Microglia and Other Cell Types in Signaling Responses to Injury; Entry of Peripheral Macrophages and Differences with Microglia; Diverse Roles of Macrophages/Microglia in CNS Injury and Disease Macrophage Polarization in SCIConcluding Remarks; Acknowledgments; References; Chapter 5 The Complexity of the Innate Immune System Activation in Stroke Pathogenesis; Activation of the Brain Innate Immunity After Stroke; Myeloid Heterogeneity in Brain Ischemia; Concluding Remarks; References; Chapter 6 Neuroinflammation in Aging; Increased CNS Inflammation in Response to Immune Challenge is Adaptive and Beneficial; The CNS Microenvironment Shifts to a Proinflammatory State with Aging; Microglial Priming; Microglial Regulation Immune Reactivity of Glia Contributes to Cognitive and Behavioral DeficitsConclusions; References; Chapter 7 Peripheral and Central Immune Mechanisms in Neuropathic Pain; Introduction; Inflammation in Neuropathic Pain; Contribution of Peripheral Immune Cells to the Pathogenesis of Neuropathic Pain; Critical Roles of Spinal Glial Activation in Neuropathic Pain; Significance of Neural Barriers in Inflammatory Response along Pain Transmission Pathway; Imbalance of Pro- and Anti-inflammatory Responses in Neuropathic Pain Challenges in Translating Anti-inflammatory Therapeutic Strategies for the Relief of~Neuropathic Pain |
| Record Nr. | UNINA-9910131152903321 |
| Hoboken, New Jersey : , : John Wiley & Sons, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neuroinflammation : new insights into beneficial and detrimental functions / / edited by Samuel David
| Neuroinflammation : new insights into beneficial and detrimental functions / / edited by Samuel David |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, , 2015 |
| Descrizione fisica | 1 online resource (322 p.) |
| Disciplina | 616.8/0479 |
| Soggetto topico |
Central nervous system - Diseases
Central nervous system - Diseases - Immunological aspects |
| ISBN |
1-118-73277-4
1-118-73274-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Title Page; Copyright; Contents; Contributors; Preface; Part I Introduction; Chapter 1 Immune Response in the Human Central Nervous System in Multiple Sclerosis and Stroke; Introduction; The Concept of Neuroinflammation; Basic Principles of Immune Surveillance and Inflammation by Adaptive Immune Responses; Inflammation in the Central Nervous System of Patients with Multiple Sclerosis; Inflammation in Stroke Lesions; Microglia Activation and Macrophage Response; Granulocyte Infiltration; Conclusions; References
Chapter 2 In Vivo Imaging of Glial and Immune Cell Responses in Central Nervous System Injury and DiseaseIntroduction; Intravital Microscopy in the CNS and Its Challenges; In Vivo Imaging of the CNS Following Sterile Injury; In Vivo Imaging of the CNS in Disorders with an Inflammatory Component; Conclusion; Acknowledgments; References; Part II Detrimental Aspects of Inflammation; Chapter 3 Roles of CD4 and CD8 T Lymphocytes in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis; Introduction; T Lymphocytes: Central Immune Cells; Autoreactive T Lymphocytes From Peripheral Activation to CNS ExtravasationRole of CD4 T Lymphocytes in MS and EAE: Th1 versus Th17; Role of CD8 T Lymphocytes in MS and EAE; Regulatory T Lymphocytes in MS and EAE; Conclusions; Acknowledgments; References; Chapter 4 Microglia and Macrophage Responses and Their Role after Spinal Cord Injury; Introduction; Microglial Responses to Injury; Interactions between Microglia and Other Cell Types in Signaling Responses to Injury; Entry of Peripheral Macrophages and Differences with Microglia; Diverse Roles of Macrophages/Microglia in CNS Injury and Disease Macrophage Polarization in SCIConcluding Remarks; Acknowledgments; References; Chapter 5 The Complexity of the Innate Immune System Activation in Stroke Pathogenesis; Activation of the Brain Innate Immunity After Stroke; Myeloid Heterogeneity in Brain Ischemia; Concluding Remarks; References; Chapter 6 Neuroinflammation in Aging; Increased CNS Inflammation in Response to Immune Challenge is Adaptive and Beneficial; The CNS Microenvironment Shifts to a Proinflammatory State with Aging; Microglial Priming; Microglial Regulation Immune Reactivity of Glia Contributes to Cognitive and Behavioral DeficitsConclusions; References; Chapter 7 Peripheral and Central Immune Mechanisms in Neuropathic Pain; Introduction; Inflammation in Neuropathic Pain; Contribution of Peripheral Immune Cells to the Pathogenesis of Neuropathic Pain; Critical Roles of Spinal Glial Activation in Neuropathic Pain; Significance of Neural Barriers in Inflammatory Response along Pain Transmission Pathway; Imbalance of Pro- and Anti-inflammatory Responses in Neuropathic Pain Challenges in Translating Anti-inflammatory Therapeutic Strategies for the Relief of~Neuropathic Pain |
| Record Nr. | UNINA-9910827392703321 |
| Hoboken, New Jersey : , : John Wiley & Sons, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||