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Infections of the cornea and conjunctiva / / edited by Sujata Das, Vishal Jhanji
| Infections of the cornea and conjunctiva / / edited by Sujata Das, Vishal Jhanji |
| Edizione | [1st ed. 2021.] |
| Pubbl/distr/stampa | Singapore : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (XVII, 278 p. 87 illus., 83 illus. in color.) |
| Disciplina | 929.605 |
| Soggetto topico |
Conjunctiva - Diseases
Eye - Infections Cornea - Diseases |
| ISBN | 981-15-8811-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Bacterial Conjunctivitis -- Viral Conjunctivitis. Chlamydial Conjunctivitis -- Ophthalmia Neonatorum -- Clinical Work-up of Corneal Ulcers -- Bacterial Keratitis -- Atypical Mycobacterial Keratitis -- Nocardia Keratitis -- Acanthamoeba Keratitis -- Microsporidial Keratitis -- Fungal Keratitis -- Pythium Keratitis -- Herpes Simplex Virus (HSV) Keratitis -- Herpes Zoster Ophthalmicus (HZO) Keratitis -- Role of Microbiology in the Diagnosis of Corneal and Conjunctival Infections -- Role of Histopathology in the Diagnosis of Corneal and Conjunctival Infections -- Role of In Vivo Confocal Microscopy in the Diagnosis of Microbial Keratitis. |
| Record Nr. | UNINA-9910484321603321 |
| Singapore : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Keratoconus : diagnosis and treatment / / Sujata Das, editor
| Keratoconus : diagnosis and treatment / / Sujata Das, editor |
| Pubbl/distr/stampa | Singapore : , : Springer, , [2022] |
| Descrizione fisica | 1 online resource (298 pages) |
| Disciplina | 617.719 |
| Soggetto topico |
Keratoconus
Keratoconus - Treatment Quality of life |
| ISBN |
9789811942624
9789811942617 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Foreword -- Foreword -- Preface -- Contents -- About the Editor -- 1: Epidemiology of Keratoconus -- 1.1 Introduction -- 1.2 Epidemiology -- 1.2.1 Incidence and Prevalence -- 1.2.2 Age of Onset -- 1.2.3 Gender -- 1.2.4 Laterality -- 1.3 Risk Factors -- 1.3.1 Genetic -- 1.3.2 Ethnic Groups -- 1.3.3 Eye Rubbing -- 1.3.4 Atopy -- 1.3.5 Ultraviolet and Sun Exposure -- 1.3.6 Hormonal -- 1.3.7 Associated Systemic and Ocular Disorders -- 1.4 Conclusion -- References -- 2: Etiology and Risk Factors of Keratoconus -- 2.1 Introduction -- 2.2 The Genetics of Keratoconus -- 2.2.1 Genome-Wide Association Studies (GWAS) -- 2.2.2 GWAS of Central Corneal Thickness (CCT) and Corneal Biomechanical Properties -- 2.3 KC and Family History -- 2.4 Functional Studies of Candidate Genes -- 2.4.1 DOCK9 and PPIP5K2 -- 2.5 Genetic Determinants of Syndromic and Non-syndromic KC -- 2.6 Transcriptomic and Expression Studies -- 2.6.1 Noncoding RNA (lncRNAs and miRNAs) Involved in KC -- 2.7 Environmental Risk Factors -- 2.7.1 Eye Rubbing -- 2.7.2 Comorbidities -- 2.7.3 Contact Lens Wear -- 2.7.4 Asthma -- 2.7.5 Allergy -- 2.7.6 Atopy -- 2.7.7 UV Exposure -- 2.8 Conclusion -- References -- 3: Biomechanics of Keratoconus -- 3.1 Introduction -- 3.2 Background -- 3.3 Biomechanical Changes -- 3.3.1 Biomechanical Changes in KCN -- 3.3.2 Biomechanical Changes in ffKCN -- 3.3.3 Biomechanical Changes After Intrastromal Corneal Ring Segments -- 3.3.4 Biomechanical Changes in CXL -- 3.3.5 Biomechanics in Refractive Surgery -- 3.4 Conclusions -- References -- 4: Pathophysiology and Histopathology of Keratoconus -- 4.1 Introduction -- 4.2 Pathophysiology of Keratoconus -- 4.2.1 Composition of the Corneal Stroma in Keratoconus -- 4.2.2 Alterations in Volume/Stromal Thinning -- 4.2.3 Alterations in Characteristics.
4.2.4 Role of Inflammatory Mediators Including TGF Beta Pathway and Cytokine Dysregulation -- 4.2.5 Imbalance of Proteolytic Enzymes -- 4.2.6 Oxidative Stresses -- 4.2.7 Cellular Hypersensitivity to Apoptosis -- 4.3 Histopathology -- 4.3.1 Penetrating Keratoplasty Specimens -- 4.3.2 Epithelial Changes -- 4.3.3 Bowman's Layer -- 4.3.4 Stroma -- 4.3.5 Dua's Layer -- 4.3.6 Descemet's Membrane -- 4.3.7 Endothelial Cells -- 4.3.8 DALK and Attempted DALK Specimens -- 4.3.9 Acute Hydrops and Healed Hydrops -- 4.3.10 Histopathological Changes After Collagen Cross-linking -- 4.4 Conclusion -- References -- 5: Clinical Diagnosis of Keratoconus -- 5.1 Introduction -- 5.2 Symptoms -- 5.3 History -- 5.3.1 Past Ocular History -- 5.3.2 Family History -- 5.3.3 Medical History and Associated Diseases -- 5.4 Clinical Examination -- References -- 6: Classifications and Patterns of Keratoconus -- 6.1 Introduction -- 6.2 Classification Systems in Keratoconus -- 6.2.1 KISA Index -- 6.2.2 McMahon and Colleagues' Keratoconus Severity Score (KSS) -- 6.3 Classification of Keratoconus Based on Clinical Characteristics -- 6.3.1 Based on Severity of the Corneal Curvature -- 6.3.2 Classification of Keratoconus Based on Morphological Appearance of the Cone -- 6.4 Amsler-Krumeich Classification -- 6.4.1 Belin ABCD Classification -- 6.5 Fourier-Domain OCT Classification -- 6.6 Topographic Patterns in Keratoconus -- 6.7 Conclusion -- References -- 7: Differential Diagnosis of Keratoconus -- 7.1 Introduction -- 7.2 True Corneal Ectasias -- 7.2.1 Pellucid Marginal Degeneration (PMD): Keratotorus -- 7.2.2 Keratoglobus -- 7.2.3 Isolated Keratoconus Posticus -- 7.2.4 Regular Astigmatism -- 7.2.5 Post-LASIK Ectasia -- 7.2.6 Superior Keratoconus and Superior Pellucid Marginal Degeneration (PMD). 7.3 Corneal Diseases with Pseudokeratoconic Tomography -- 7.3.1 Epithelial Basement Membrane Dystrophy (EBMD) -- 7.3.2 Scar-Associated Irregular Astigmatism -- 7.3.3 Central Fuchs Endothelial Corneal Dystrophy -- 7.4 Differential Diagnosis of Corneal Hydrops -- 7.4.1 Salzmann's Nodular and Peripheral Hypertrophic Subepithelial Corneal Degeneration (PHSCD) -- References -- 8: Keratoconus in Children -- 8.1 Introduction -- 8.2 Epidemiology -- 8.3 Genetics -- 8.4 Ocular Allergy -- 8.5 Syndromes -- 8.6 Risk Factors -- 8.7 Clinical Features and Diagnosis -- 8.8 Adult vs. Pediatric Keratoconus -- 8.9 Treatment -- 8.10 Contact Lens -- 8.11 Surgical Procedures -- 8.11.1 Collagen Cross-linking -- 8.11.1.1 Indications and Timing of the Procedure in Children vs. Adolescent -- 8.11.2 CXL Standard Dresden Protocol -- 8.11.3 Transepithelial CXL (TE CXL) -- 8.11.4 Accelerated Cross-linking Protocol -- 8.11.5 Other Methods -- 8.11.6 Safety -- 8.11.6.1 Epithelial Defect -- 8.11.6.2 Endothelial Cell Loss -- 8.11.6.3 Limbal Cell Loss -- 8.11.6.4 Efficacy of Standard Protocol -- 8.11.6.5 Efficacy of Transepithelial CXL (EPI-ON) and Accelerated Protocol -- 8.11.7 Intracorneal Ring Segments -- 8.11.8 Keratoplasty -- References -- 9: Allergic Eye Disease and Keratoconus -- 9.1 Introduction -- 9.2 Association between Allergic Eye Diseases and Keratoconus -- 9.3 Etiopathogenesis -- 9.3.1 Causative Factors -- 9.3.2 Genetic Factors -- 9.3.3 Environmental Factors -- 9.3.4 Role of Inflammation -- 9.3.5 Role of Enzymes -- 9.3.6 Role of Oxidative Stress -- 9.3.7 Role of Hormones -- 9.4 Role of Early Topography in Allergic Eye Diseases -- 9.5 Role of Allergic Eye Diseases in KC Progression -- 9.6 Role of Allergic Eye Diseases in Acute Corneal Hydrops and Perforation -- 9.7 Management of Allergic Eye Disorders. 9.7.1 Treatment Options for Ocular Allergy -- 9.7.1.1 Avoidance of Allergen -- 9.7.1.2 Cold Compresses -- 9.7.1.3 Artificial Tear Substitutes -- 9.7.1.4 Topical Antihistamine -- 9.7.1.5 Topical Vasoconstrictors -- 9.7.1.6 Topical Mast Cell Stabilizers -- 9.7.1.7 Multimodal Anti-Allergic Agents -- 9.7.1.8 Topical Corticosteroids -- 9.7.1.9 Topical Immunomodulatory Agents -- 9.7.1.10 Systemic Agents -- 9.8 Prevention of Eye Rubbing -- 9.9 Surgical Treatment -- 9.9.1 Surgical Outcome in Cases with Allergic Eye Diseases and KC -- 9.10 Conclusion -- References -- 10: Topography and Tomography of Keratoconus -- 10.1 Introduction -- 10.2 Topography Vs. Tomography -- 10.2.1 Historical Background -- 10.3 Placido-Based Corneal Topographer -- 10.3.1 Principle -- 10.3.2 Features -- 10.3.3 Application Tools for Keratoconus Management -- 10.4 Scheimpflug-Based Tomography -- 10.4.1 Principle -- 10.4.2 Features -- 10.4.3 Application Tools for Keratoconus Management -- 10.5 Anterior Segment OCT -- 10.5.1 Principle -- 10.5.2 Feature -- 10.5.3 Application Tools for Keratoconus Management -- 10.6 Combined Systems with a Wavefront Aberrometer -- 10.7 Tips for the Measurements -- 10.8 Tips at Reading the Maps -- 10.9 Final Practical Comment from Specialists -- References -- 11: Newer Diagnostic Technology for Diagnosis of Keratoconus -- 11.1 Introduction -- 11.2 Corneal Topography -- 11.2.1 Types of Topographic Indices -- 11.3 Epithelial Mapping in Keratoconus -- 11.3.1 Classification of OCT-Based Devices -- 11.3.1.1 RTVUE® -- 11.3.1.2 CASIA 2 -- 11.3.1.3 MS-39: A Hybrid Tomographer -- 11.3.2 Importance of Epithelial Mapping in Diagnosis of Subclinical Keratoconus -- 11.3.3 Imaging the Bowman's Layer in Subclinical and Clinical Keratoconus -- 11.3.4 Epithelial Changes in Keratoconus -- 11.3.5 True Progression in Keratoconus. 11.3.6 Pseudoprogression in Keratoconus -- 11.3.7 Epithelial Remodeling Post-Cross-Linking -- 11.3.8 Importance of Epithelial Imaging in Identifying Keratoconus Masquerades -- 11.3.9 Clinical Applications -- 11.4 Corneal Biomechanics -- 11.4.1 Introduction -- 11.4.2 Ocular Response Analyzer -- 11.4.2.1 Application in Keratoconus -- 11.4.3 Corvis ST -- 11.4.3.1 Vinciguerra Screening Report -- 11.4.3.2 TBI (Tomographic/Biomechanical Index) -- 11.4.3.3 Biomechanics Comparative Display -- 11.4.4 Clinical Applications -- 11.5 Confocal Microscopy -- 11.5.1 Introduction -- 11.5.2 Principle -- 11.5.2.1 Tandem Scanning Confocal Microscope (TSCM) -- 11.5.2.2 Scanning Slit Confocal Microscope (SSCM) -- 11.5.2.3 Confocal Laser Scanning Microscope (CLSM) -- 11.5.3 Confocal Microscopy in Normal -- 11.5.3.1 Corneal Epithelium -- Superficial Cells -- Wing Cells -- Basal Cells -- 11.5.3.2 Bowman's Membrane -- 11.5.3.3 Corneal Stroma -- 11.5.3.4 Descemet's Membrane -- 11.5.4 Confocal Microscopy in Keratoconus -- 11.5.4.1 Corneal Epithelium -- Superficial Cells -- Basal Cells -- 11.5.4.2 Bowman's Membrane -- 11.5.4.3 Corneal Stroma -- 11.5.4.4 Corneal Nerves in Keratoconus -- 11.5.4.5 Descemet's Membrane -- 11.5.5 Clinical Applications -- 11.6 Polarization-Sensitive Optical Coherence Tomography (PS-OCT) -- 11.6.1 Introduction -- 11.6.2 Principle of PS-OCT -- 11.6.3 Corneal Imaging Using PS-OCT -- 11.6.4 Clinical Applications -- 11.6.4.1 Normal Patients -- 11.6.4.2 Keratoconus -- 11.6.4.3 Post-Corneal Collagen Cross-Linking -- 11.7 Brillouin Microscopy -- 11.7.1 Introduction -- 11.7.2 Principle of Brillouin Microscopy -- 11.7.3 Clinical Applications [73] -- 11.7.3.1 Screening/Diagnosis of Corneal Disease -- 11.7.3.2 Monitoring Response to Corneal Cross-Linking -- 11.7.3.3 Advantages. 11.8 MMP-9 Kit Useful in the Diagnosis of Molecular Markers for Keratoconus. |
| Record Nr. | UNINA-9910619278303321 |
| Singapore : , : Springer, , [2022] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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