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Cancer Biomarkers in Body Fluids [[electronic resource] ] : Biomarkers in Proximal Fluids / / by Gabriel D. Dakubo
| Cancer Biomarkers in Body Fluids [[electronic resource] ] : Biomarkers in Proximal Fluids / / by Gabriel D. Dakubo |
| Autore | Dakubo Gabriel D |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (306 pages) |
| Disciplina | 616.994075 |
| Soggetto topico |
Human genetics
Oncology Cancer research Human Genetics Oncology Cancer Research |
| ISBN | 3-030-24725-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Melanoma Biomarkers in Exfoliated Cells -- 2. Head and Neck Cancer Biomarkers in Saliva -- 3. Lung Cancer Biomarkers in Lung Fluids -- 4. Breast Cancer Biomarkers in Breast Fluids -- 5. Gastric Cancer Biomarkers in Gastric Fluid -- 6. Colorectal Cancer Biomarkers in Stool -- 7. Hepatobiliary Cancer Biomarkers in Bile -- 8. Pancreatic Cancer Biomarkers in Pancreatic Juice -- 9. Renal Cancer Biomarkers in Urine -- 10. Bladder Cancer Biomarkers in Urine -- 11. Prostate Cancer Biomarkers in Prostatic Fluid -- 12. Testicular Cancer Biomarkers in Seminal Fluid -- 13. Ovarian Cancer Biomarkers in Peritoneal Fluid -- 14. Endometrial Cancer Biomarkers in Menstrual Fluid -- 15. Cervical and Vulvar Cancer Biomarkers in Exfoliated Cells -- 16. Brain Cancer Biomarkers in Cerebrospinal Fluid -- 17. Hematologic Cancer Biomarkers in Blood -- 18. The Body Fluid Microbiome and Cancer -- 19. Biomarkers in Interstitial Fluids of Cancer Cells. |
| Record Nr. | UNINA-9910349446103321 |
Dakubo Gabriel D
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| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Biomarkers in Body Fluids [[electronic resource] ] : Biomarkers in Circulation / / by Gabriel D. Dakubo
| Cancer Biomarkers in Body Fluids [[electronic resource] ] : Biomarkers in Circulation / / by Gabriel D. Dakubo |
| Autore | Dakubo Gabriel D |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (XIX, 509 p. 20 illus. in color.) |
| Disciplina |
611.01816
599.935 |
| Soggetto topico |
Human genetics
Oncology Cancer research Human Genetics Oncology Cancer Research |
| ISBN | 9783319483603 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910155302903321 |
|
Dakubo Gabriel D
|
||
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Cancer Biomarkers in Body Fluids [[electronic resource] ] : Principles / / by Gabriel D. Dakubo
| Cancer Biomarkers in Body Fluids [[electronic resource] ] : Principles / / by Gabriel D. Dakubo |
| Autore | Dakubo Gabriel D |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (311 p.) |
| Disciplina | 610 |
| Soggetto topico |
Human genetics
Oncology Cancer research Human Genetics Oncology Cancer Research |
| ISBN | 3-319-01580-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Preface; Contents; Chapter 1: Molecular Pathology of Cancer; Key Topics; 1.1 Introduction; 1.2 Functional Anatomy of the Cancer Cell; 1.3 History of Cancer Molecular Pathology; 1.4 Causes and Risk Factors of Cancer; 1.4.1 Infectious Causes of Cancer and Circulating Biomarkers; 1.5 The Biology of Cancer and Biomarkers; 1.6 Mutations as Cancer Biomarkers; 1.7 DNA Repair Mechanisms; 1.7.1 Direct Repair System; 1.7.2 Excision Repair; 1.7.2.1 Base-Excision Repair; 1.7.2.2 Nucleotide-Excision Repair; 1.7.2.3 Mismatch Repair; 1.7.3 Repair of Double-Strand Breaks
1.8 Oncogene and Tumor Suppressor Gene Alterations as Biomarkers1.9 Cancer Signaling Pathway Alterations as Biomarkers; 1.9.1 The Receptor Tyrosine Kinase (RTK) Signaling Pathway; 1.9.2 The Phosphoinositide 3-Kinase (PI3K) Signaling Pathway; 1.9.3 The Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway; 1.9.4 The Mesenchymal-Epithelial Transition (MET) Factor Signaling Pathway; 1.9.5 The Janus Kinase (JAK) Signaling Pathway; 1.9.6 The Transforming Growth Factor-Beta (TGFbeta) Signaling Pathway; 1.9.7 The Nuclear Factor-kB (NF-kB) Signaling Pathway; 1.9.8 Src Signaling in Cancer Invasion 1.9.9 Control of the Cell Cycle1.9.10 Hypoxia-Inducible Factor Signaling; 1.9.11 The WNT/beta-Catenin Signaling Pathway; 1.9.12 The Hedgehog Signaling Pathway; 1.9.13 The Notch Signaling Pathway; 1.10 Cell Death Processes and Cancer; 1.10.1 Nomenclature for Cell Death Processes; 1.10.2 Apoptosis; 1.10.3 Cancer Initiation as Defects in Apoptosis; 1.11 Multistep Carcinogenesis and Early Detection Cancer Biomarkers; 1.12 Personalized Cancer Care; 1.12.1 Nomenclature of Targeted Therapies; 1.12.2 Tests of Interest in Personalized Oncology; 1.13 Epigenetic Modifications and Cancer 1.13.1 DNA Methylation1.13.2 Histone Modification; 1.13.3 The Cancer Cell Epigenome; 1.14 Genetic Alterations in Cancer; 1.14.1 Chromosomal Alterations; 1.14.1.1 Chromosomal Instability; 1.14.1.2 Microsatellite Alterations; 1.14.1.3 Gene Amplification; 1.14.1.4 Telomere Dysfunction; 1.14.2 Gene Mutations; 1.14.2.1 Cancer Genome Consortia; 1.15 The Cancer Cell Transcriptome; 1.16 The Proteome or Peptidome; 1.16.1 Serum Peptidome; 1.16.2 Serum vs. Plasma Proteomics; 1.16.3 Issues with Proteomic Biomarker Studies; 1.17 The Cancer Cell Metabolome; 1.17.1 Body Fluid Metabolomics; 1.18 Summary Internet ResourcesReferences; Chapter 2: Advanced Technologies for Body Fluid Biomarker Analyses; Key Topics; 2.1 Introduction; 2.2 High-Throughput Technologies for Biomarker Analyses; 2.3 Next-Generation Sequencing; 2.4 Single-Cell Analysis; 2.4.1 Whole Genome Amplification; 2.4.2 Whole Transcriptome Amplification; 2.4.3 Whole Genome Analysis of Circulating Tumor Cells; 2.5 Proteomic Technologies for Body Fluid Analysis; 2.6 Gel Based (2D and DIGE); 2.7 Non-gel-based Proteomic Techniques; 2.7.1 Mass Spectrometry; 2.7.1.1 Matrix-Assisted Laser Desorption/Ionization (MALDI)-MS 2.7.1.2 Electrospray Ionization (ESI) |
| Record Nr. | UNINA-9910253896603321 |
|
Dakubo Gabriel D
|
||
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||