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Brush border membranes [[electronic resource]]
| Brush border membranes [[electronic resource]] |
| Pubbl/distr/stampa | London, : Pitman, c1983 |
| Descrizione fisica | 1 online resource (352 p.) |
| Disciplina |
611.0181
611/.0181 |
| Altri autori (Persone) |
PorterRuth
CollinsGeralyn M |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Cell membranes
Cell physiology |
| ISBN |
1-280-78402-4
9786613694416 0-470-72076-X 0-470-71846-3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Brush border membranes; Contents; Chairman's introduction; Introductory remarks on the brush border; Microvillar endopeptidase, an enzyme with special topological features and a wide distribution; Discussion; Aminopeptidases and proteolipids of intestinal brush border; Discussion; Structure of microvillar enzymes in different phases of their life cycles; Discussion; Specific labelling of the hydrophobic domain of rat renal y-glutamyl transferase; Discussion; Biosynthesis and assembly of the largest and major intrinsic polypeptide of the small intestinal brush borders; Discussion
Use of monoclonal antibodies in the study of intestinal structure and function Discussion; Biosynthesis and transport of plasma membrane glyco- proteins in the rat intestinal epithelial cell: studies with sucrase- isomaltase; Discussion; GENERAL DISCUSSION I Biosynthesis and assembly of brush border proteins: (i) some co-translational models for protein insertion into membranes; molecular sizes of brush border enzymes during assembly; Distribution of enteropeptidase and aminopeptidase to non-brush border sites; General functions of the enterocyte Molecular architecture of the microvillus cytoskeleton Discussion; Structure of human placental microvilli; Discussion; Regulation of cytoskeletal structure and contractility in the brush border; Discussion; Characterization of membrane glycoproteins involved in attachment of microfilaments to the microvillar membrane; Discussion; Structural and functional relationship between the membrane and the cytoskeleton in brush border microvilli; Discussion; GENERAL DISCUSSION II A pathological condition due to congenital disorganization of the brush border Conformational changes in the a-subunit, and cation transport by Na+, K+-ATPase Discussion; Properties of immunoglobulin G-Fc receptors from neonatal rat intestinal brush borders; Immunoglobulin G receptors of intestinal brush borders from neonatal rats; Discussion after the preceding two papers; Cotransport systems in the brush border membrane of the human placenta; Discussion; GENERAL DISCUSSION III Cytoskeleton and membrane-cytoskeleton interactions; The importance of structure for understanding the biosynthetic process; Future advances in study of brush border cytoskeleton Photo-affinity labeling to identify components of the neutral amino acid carrier in the intestinal microvillar membrane Chairman's closing remarks; Index to contributors; Subject index |
| Record Nr. | UNISA-996206954703316 |
| London, : Pitman, c1983 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Brush border membranes [[electronic resource]]
| Brush border membranes [[electronic resource]] |
| Pubbl/distr/stampa | London, : Pitman, c1983 |
| Descrizione fisica | 1 online resource (352 p.) |
| Disciplina |
611.0181
611/.0181 |
| Altri autori (Persone) |
PorterRuth
CollinsGeralyn M |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Cell membranes
Cell physiology |
| ISBN |
1-280-78402-4
9786613694416 0-470-72076-X 0-470-71846-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Brush border membranes; Contents; Chairman's introduction; Introductory remarks on the brush border; Microvillar endopeptidase, an enzyme with special topological features and a wide distribution; Discussion; Aminopeptidases and proteolipids of intestinal brush border; Discussion; Structure of microvillar enzymes in different phases of their life cycles; Discussion; Specific labelling of the hydrophobic domain of rat renal y-glutamyl transferase; Discussion; Biosynthesis and assembly of the largest and major intrinsic polypeptide of the small intestinal brush borders; Discussion
Use of monoclonal antibodies in the study of intestinal structure and function Discussion; Biosynthesis and transport of plasma membrane glyco- proteins in the rat intestinal epithelial cell: studies with sucrase- isomaltase; Discussion; GENERAL DISCUSSION I Biosynthesis and assembly of brush border proteins: (i) some co-translational models for protein insertion into membranes; molecular sizes of brush border enzymes during assembly; Distribution of enteropeptidase and aminopeptidase to non-brush border sites; General functions of the enterocyte Molecular architecture of the microvillus cytoskeleton Discussion; Structure of human placental microvilli; Discussion; Regulation of cytoskeletal structure and contractility in the brush border; Discussion; Characterization of membrane glycoproteins involved in attachment of microfilaments to the microvillar membrane; Discussion; Structural and functional relationship between the membrane and the cytoskeleton in brush border microvilli; Discussion; GENERAL DISCUSSION II A pathological condition due to congenital disorganization of the brush border Conformational changes in the a-subunit, and cation transport by Na+, K+-ATPase Discussion; Properties of immunoglobulin G-Fc receptors from neonatal rat intestinal brush borders; Immunoglobulin G receptors of intestinal brush borders from neonatal rats; Discussion after the preceding two papers; Cotransport systems in the brush border membrane of the human placenta; Discussion; GENERAL DISCUSSION III Cytoskeleton and membrane-cytoskeleton interactions; The importance of structure for understanding the biosynthetic process; Future advances in study of brush border cytoskeleton Photo-affinity labeling to identify components of the neutral amino acid carrier in the intestinal microvillar membrane Chairman's closing remarks; Index to contributors; Subject index |
| Record Nr. | UNINA-9910144654903321 |
| London, : Pitman, c1983 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Brush border membranes
| Brush border membranes |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | London, : Pitman, c1983 |
| Descrizione fisica | 1 online resource (352 p.) |
| Disciplina |
611.0181
611/.0181 |
| Altri autori (Persone) |
PorterRuth
CollinsGeralyn M |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Cell membranes
Cell physiology |
| ISBN |
1-280-78402-4
9786613694416 0-470-72076-X 0-470-71846-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Brush border membranes; Contents; Chairman's introduction; Introductory remarks on the brush border; Microvillar endopeptidase, an enzyme with special topological features and a wide distribution; Discussion; Aminopeptidases and proteolipids of intestinal brush border; Discussion; Structure of microvillar enzymes in different phases of their life cycles; Discussion; Specific labelling of the hydrophobic domain of rat renal y-glutamyl transferase; Discussion; Biosynthesis and assembly of the largest and major intrinsic polypeptide of the small intestinal brush borders; Discussion
Use of monoclonal antibodies in the study of intestinal structure and function Discussion; Biosynthesis and transport of plasma membrane glyco- proteins in the rat intestinal epithelial cell: studies with sucrase- isomaltase; Discussion; GENERAL DISCUSSION I Biosynthesis and assembly of brush border proteins: (i) some co-translational models for protein insertion into membranes; molecular sizes of brush border enzymes during assembly; Distribution of enteropeptidase and aminopeptidase to non-brush border sites; General functions of the enterocyte Molecular architecture of the microvillus cytoskeleton Discussion; Structure of human placental microvilli; Discussion; Regulation of cytoskeletal structure and contractility in the brush border; Discussion; Characterization of membrane glycoproteins involved in attachment of microfilaments to the microvillar membrane; Discussion; Structural and functional relationship between the membrane and the cytoskeleton in brush border microvilli; Discussion; GENERAL DISCUSSION II A pathological condition due to congenital disorganization of the brush border Conformational changes in the a-subunit, and cation transport by Na+, K+-ATPase Discussion; Properties of immunoglobulin G-Fc receptors from neonatal rat intestinal brush borders; Immunoglobulin G receptors of intestinal brush borders from neonatal rats; Discussion after the preceding two papers; Cotransport systems in the brush border membrane of the human placenta; Discussion; GENERAL DISCUSSION III Cytoskeleton and membrane-cytoskeleton interactions; The importance of structure for understanding the biosynthetic process; Future advances in study of brush border cytoskeleton Photo-affinity labeling to identify components of the neutral amino acid carrier in the intestinal microvillar membrane Chairman's closing remarks; Index to contributors; Subject index |
| Record Nr. | UNINA-9910828254603321 |
| London, : Pitman, c1983 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Development of the autonomic nervous system [[electronic resource] /] / [Katherine Elliott and Geralyn Lawrenson, editors]
| Development of the autonomic nervous system [[electronic resource] /] / [Katherine Elliott and Geralyn Lawrenson, editors] |
| Pubbl/distr/stampa | London, : Pitman, 1981 |
| Descrizione fisica | 1 online resource (402 p.) |
| Disciplina |
612
612/.89 |
| Altri autori (Persone) |
ElliottKatherine
CollinsGeralyn M |
| Collana | Ciba Foundation symposium |
| Soggetto topico | Autonomic nervous system |
| ISBN |
0-470-72065-4
0-470-71834-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Development of the autonomic nervous system; Contents; Current approaches to development of the autonomic nervous system: clues to clinical problems; Discussion; Plasticity in the development of the peripheral nervous system; Discussion; Development of enteric neurons from non-recognizable precursor cells; Discussion; Autonomic regulation of cardiovascular function in neonates; Discussion; Developmental influences on vascular structure and function; Discussion; Growth and development of sympathetic neurons in tissue culture
Adrenergic-cholinergic dual function in cultured sympathetic neurons of the ratDISCUSSION OF THE TWO PRECEDING PAPERS; In vitro responses of sympathetic neurons to nerve growth factor and other macromolecular agents; Discussion; Transmitter phenotypic expression in the embryo; Discussion; Interactions between developing autonomic neurons and their target tissues; Discussion; Factors regulating growth of catecholamine-containing nerves, as revealed by transplantation and ex- plantation studies; Discussion; Regulation of synaptic connections in the rabbit ciliary ganglion; Discussion Pregnancy induces degenerative and regenerative changes in the autonomic innervation of the female reproductive tractDiscussion; GENERAL DISCUSSION; Cholinergic synapse development in chick sympathetic ganglia; Effect of substratum on neurite outgrowth in vitro; The link between laboratory work and clinical practice; The autonomic nervous system and perinatal metabolism; Discussion; Fetal cardiovascular reactions during labour and asphyxia modified by adrenergic receptor agonists and antagonists; Discussion Myenteric plexus of the hind-gut: developmental abnormalities in humans and experimental studiesDiscussion; FINAL GENERAL DISCUSSION; Hirschsprung's disease: embryological aspects and basic mechanisms; Nerve growth factor and other trophic factors in conditioned media (with some immunological considerations); Chairman's concluding remarks; Index of contributors; Subject index |
| Record Nr. | UNINA-9910144656203321 |
| London, : Pitman, 1981 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Development of the autonomic nervous system [[electronic resource] /] / [Katherine Elliott and Geralyn Lawrenson, editors]
| Development of the autonomic nervous system [[electronic resource] /] / [Katherine Elliott and Geralyn Lawrenson, editors] |
| Pubbl/distr/stampa | London, : Pitman, 1981 |
| Descrizione fisica | 1 online resource (402 p.) |
| Disciplina |
612
612/.89 |
| Altri autori (Persone) |
ElliottKatherine
CollinsGeralyn M |
| Collana | Ciba Foundation symposium |
| Soggetto topico | Autonomic nervous system |
| ISBN |
0-470-72065-4
0-470-71834-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Development of the autonomic nervous system; Contents; Current approaches to development of the autonomic nervous system: clues to clinical problems; Discussion; Plasticity in the development of the peripheral nervous system; Discussion; Development of enteric neurons from non-recognizable precursor cells; Discussion; Autonomic regulation of cardiovascular function in neonates; Discussion; Developmental influences on vascular structure and function; Discussion; Growth and development of sympathetic neurons in tissue culture
Adrenergic-cholinergic dual function in cultured sympathetic neurons of the ratDISCUSSION OF THE TWO PRECEDING PAPERS; In vitro responses of sympathetic neurons to nerve growth factor and other macromolecular agents; Discussion; Transmitter phenotypic expression in the embryo; Discussion; Interactions between developing autonomic neurons and their target tissues; Discussion; Factors regulating growth of catecholamine-containing nerves, as revealed by transplantation and ex- plantation studies; Discussion; Regulation of synaptic connections in the rabbit ciliary ganglion; Discussion Pregnancy induces degenerative and regenerative changes in the autonomic innervation of the female reproductive tractDiscussion; GENERAL DISCUSSION; Cholinergic synapse development in chick sympathetic ganglia; Effect of substratum on neurite outgrowth in vitro; The link between laboratory work and clinical practice; The autonomic nervous system and perinatal metabolism; Discussion; Fetal cardiovascular reactions during labour and asphyxia modified by adrenergic receptor agonists and antagonists; Discussion Myenteric plexus of the hind-gut: developmental abnormalities in humans and experimental studiesDiscussion; FINAL GENERAL DISCUSSION; Hirschsprung's disease: embryological aspects and basic mechanisms; Nerve growth factor and other trophic factors in conditioned media (with some immunological considerations); Chairman's concluding remarks; Index of contributors; Subject index |
| Record Nr. | UNISA-996206959603316 |
| London, : Pitman, 1981 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Development of the autonomic nervous system [[electronic resource] /] / [Katherine Elliott and Geralyn Lawrenson, editors]
| Development of the autonomic nervous system [[electronic resource] /] / [Katherine Elliott and Geralyn Lawrenson, editors] |
| Pubbl/distr/stampa | London, : Pitman, 1981 |
| Descrizione fisica | 1 online resource (402 p.) |
| Disciplina |
612
612/.89 |
| Altri autori (Persone) |
ElliottKatherine
CollinsGeralyn M |
| Collana | Ciba Foundation symposium |
| Soggetto topico | Autonomic nervous system |
| ISBN |
0-470-72065-4
0-470-71834-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Development of the autonomic nervous system; Contents; Current approaches to development of the autonomic nervous system: clues to clinical problems; Discussion; Plasticity in the development of the peripheral nervous system; Discussion; Development of enteric neurons from non-recognizable precursor cells; Discussion; Autonomic regulation of cardiovascular function in neonates; Discussion; Developmental influences on vascular structure and function; Discussion; Growth and development of sympathetic neurons in tissue culture
Adrenergic-cholinergic dual function in cultured sympathetic neurons of the ratDISCUSSION OF THE TWO PRECEDING PAPERS; In vitro responses of sympathetic neurons to nerve growth factor and other macromolecular agents; Discussion; Transmitter phenotypic expression in the embryo; Discussion; Interactions between developing autonomic neurons and their target tissues; Discussion; Factors regulating growth of catecholamine-containing nerves, as revealed by transplantation and ex- plantation studies; Discussion; Regulation of synaptic connections in the rabbit ciliary ganglion; Discussion Pregnancy induces degenerative and regenerative changes in the autonomic innervation of the female reproductive tractDiscussion; GENERAL DISCUSSION; Cholinergic synapse development in chick sympathetic ganglia; Effect of substratum on neurite outgrowth in vitro; The link between laboratory work and clinical practice; The autonomic nervous system and perinatal metabolism; Discussion; Fetal cardiovascular reactions during labour and asphyxia modified by adrenergic receptor agonists and antagonists; Discussion Myenteric plexus of the hind-gut: developmental abnormalities in humans and experimental studiesDiscussion; FINAL GENERAL DISCUSSION; Hirschsprung's disease: embryological aspects and basic mechanisms; Nerve growth factor and other trophic factors in conditioned media (with some immunological considerations); Chairman's concluding remarks; Index of contributors; Subject index |
| Record Nr. | UNINA-9910818859803321 |
| London, : Pitman, 1981 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Metabolic acidosis / / [editors, Ruth Porter, Geralyn Lawrenson]
| Metabolic acidosis / / [editors, Ruth Porter, Geralyn Lawrenson] |
| Pubbl/distr/stampa | London, : Pitman |
| Descrizione fisica | 1 online resource (406 pages) |
| Disciplina | 616.3/99 |
| Altri autori (Persone) |
PorterRuth
CollinsGeralyn M |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Acidosis
Metabolism - Disorders |
| ISBN |
1-280-78400-8
9786613694393 0-470-72069-7 0-470-71838-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Metabolic acidosis; Contents; The hydrogen ion in normal metabolism; Discussion; The techniques and uses of intracellular pH measurements; Discussion; Energy metabolism and cellular pH in normal and pathological conditions. A new look through 31phosphorus nuclear magnetic resonance; Discussion; Acidosis and contractility of heart muscle; Discussion; Lactic acidosis in the brain: occurrence, triggering mechanisms and pathophysiological importance; Discussion; Glutamine metabolism in metabolic acidosis; Discussion; The regulation of ketogenesis; Discussion; General discussion I
Fasting and ketone body metabolism Metabolic acidosis in exercise: (i) The fate of carboxylate ions during exercise; (ii) Clinical measurements of lactate loads; Preliminary observations on the metabolic responses to exercise in humans, using 31phosphorus nuclear magnetic resonance; Discussion; Metabolic acidosis and changes in water and electrolyte balance after maximal exercise; Some hormonal influences on glucose and ketone body metabolism in normal human subjects; Discussion; Effects of free fatty acids, insulin, glucagon and adrenaline on ketone body production in humans; Discussion Quantitative aspects of L(+)-lactate metabolism in human beings Discussion; The role of catecholamines in metabolic acidosis; Discussion; Acid-base balance in diabetic ketoacidosis; Discussion; Isotope turnover studies in uncontrolled diabetes and the effects of insulin; Discussion; Metabolic acidosis in the critically ill; Discussion; The role of altered lactate kinetics in the pathogenesis of Type B lactic acidosis; Discussion; Organic acidurias: approach, results and clinical relevance; Discussion; Problems in the congenital lactic acidoses; Discussion; GENERAL DISCUSSION II Regulation of energy metabolism, gluconeogenesis and ketogenesis The role of lactate in exercise; The relationship between intracellular and extracellular pH; Hormonal regulation of ketogenesis; Treatment of metabolic acidosis; Chairman's summary; Appendix; Index of contributors; Subject index |
| Record Nr. | UNINA-9910144655803321 |
| London, : Pitman | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Metabolic acidosis / / [editors, Ruth Porter, Geralyn Lawrenson]
| Metabolic acidosis / / [editors, Ruth Porter, Geralyn Lawrenson] |
| Pubbl/distr/stampa | London, : Pitman |
| Descrizione fisica | 1 online resource (406 pages) |
| Disciplina | 616.3/99 |
| Altri autori (Persone) |
PorterRuth
CollinsGeralyn M |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Acidosis
Metabolism - Disorders |
| ISBN |
1-280-78400-8
9786613694393 0-470-72069-7 0-470-71838-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Metabolic acidosis; Contents; The hydrogen ion in normal metabolism; Discussion; The techniques and uses of intracellular pH measurements; Discussion; Energy metabolism and cellular pH in normal and pathological conditions. A new look through 31phosphorus nuclear magnetic resonance; Discussion; Acidosis and contractility of heart muscle; Discussion; Lactic acidosis in the brain: occurrence, triggering mechanisms and pathophysiological importance; Discussion; Glutamine metabolism in metabolic acidosis; Discussion; The regulation of ketogenesis; Discussion; General discussion I
Fasting and ketone body metabolism Metabolic acidosis in exercise: (i) The fate of carboxylate ions during exercise; (ii) Clinical measurements of lactate loads; Preliminary observations on the metabolic responses to exercise in humans, using 31phosphorus nuclear magnetic resonance; Discussion; Metabolic acidosis and changes in water and electrolyte balance after maximal exercise; Some hormonal influences on glucose and ketone body metabolism in normal human subjects; Discussion; Effects of free fatty acids, insulin, glucagon and adrenaline on ketone body production in humans; Discussion Quantitative aspects of L(+)-lactate metabolism in human beings Discussion; The role of catecholamines in metabolic acidosis; Discussion; Acid-base balance in diabetic ketoacidosis; Discussion; Isotope turnover studies in uncontrolled diabetes and the effects of insulin; Discussion; Metabolic acidosis in the critically ill; Discussion; The role of altered lactate kinetics in the pathogenesis of Type B lactic acidosis; Discussion; Organic acidurias: approach, results and clinical relevance; Discussion; Problems in the congenital lactic acidoses; Discussion; GENERAL DISCUSSION II Regulation of energy metabolism, gluconeogenesis and ketogenesis The role of lactate in exercise; The relationship between intracellular and extracellular pH; Hormonal regulation of ketogenesis; Treatment of metabolic acidosis; Chairman's summary; Appendix; Index of contributors; Subject index |
| Record Nr. | UNISA-996206958103316 |
| London, : Pitman | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Metabolic acidosis / / [editors, Ruth Porter, Geralyn Lawrenson]
| Metabolic acidosis / / [editors, Ruth Porter, Geralyn Lawrenson] |
| Pubbl/distr/stampa | London, : Pitman |
| Descrizione fisica | 1 online resource (406 pages) |
| Disciplina | 616.3/99 |
| Altri autori (Persone) |
PorterRuth
CollinsGeralyn M |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Acidosis
Metabolism - Disorders |
| ISBN |
1-280-78400-8
9786613694393 0-470-72069-7 0-470-71838-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Metabolic acidosis; Contents; The hydrogen ion in normal metabolism; Discussion; The techniques and uses of intracellular pH measurements; Discussion; Energy metabolism and cellular pH in normal and pathological conditions. A new look through 31phosphorus nuclear magnetic resonance; Discussion; Acidosis and contractility of heart muscle; Discussion; Lactic acidosis in the brain: occurrence, triggering mechanisms and pathophysiological importance; Discussion; Glutamine metabolism in metabolic acidosis; Discussion; The regulation of ketogenesis; Discussion; General discussion I
Fasting and ketone body metabolism Metabolic acidosis in exercise: (i) The fate of carboxylate ions during exercise; (ii) Clinical measurements of lactate loads; Preliminary observations on the metabolic responses to exercise in humans, using 31phosphorus nuclear magnetic resonance; Discussion; Metabolic acidosis and changes in water and electrolyte balance after maximal exercise; Some hormonal influences on glucose and ketone body metabolism in normal human subjects; Discussion; Effects of free fatty acids, insulin, glucagon and adrenaline on ketone body production in humans; Discussion Quantitative aspects of L(+)-lactate metabolism in human beings Discussion; The role of catecholamines in metabolic acidosis; Discussion; Acid-base balance in diabetic ketoacidosis; Discussion; Isotope turnover studies in uncontrolled diabetes and the effects of insulin; Discussion; Metabolic acidosis in the critically ill; Discussion; The role of altered lactate kinetics in the pathogenesis of Type B lactic acidosis; Discussion; Organic acidurias: approach, results and clinical relevance; Discussion; Problems in the congenital lactic acidoses; Discussion; GENERAL DISCUSSION II Regulation of energy metabolism, gluconeogenesis and ketogenesis The role of lactate in exercise; The relationship between intracellular and extracellular pH; Hormonal regulation of ketogenesis; Treatment of metabolic acidosis; Chairman's summary; Appendix; Index of contributors; Subject index |
| Record Nr. | UNINA-9910828254803321 |
| London, : Pitman | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular approaches to human polygenic disease [[electronic resource]]
| Molecular approaches to human polygenic disease [[electronic resource]] |
| Pubbl/distr/stampa | Chichester ; ; New York, : Wiley, 1987 |
| Descrizione fisica | 1 online resource (286 p.) |
| Disciplina |
616
616.042 |
| Altri autori (Persone) |
BockGregory
CollinsGeralyn M |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Genetic disorders
Medical genetics Molecular genetics |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-282-13790-5
9786612137907 0-470-51350-0 0-470-51351-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
MOLECULAR APPROACHES TO HUMAN POLYGENIC DISEASE; Contents; Participants; Introduction; Human gene mapping; Genetics of coronary heart disease and its risk factors; The LDL receptor: oligonucleotide-directed mutagenesis of the cytoplasmic domain; Apolipoproteins, quantitative I i poprotei n traits and mu It ifactorial hyperli pidaemia; Structure and evolution of human apolipoprotein genes: identification of regulatory elements of the human apolipoprotein Egene; General discussion
Genetic architecture of inter-individual variabi I i ty i n apol i pop rot ei n , I i pop rot ei n and lipid phenotypesUse of DNA polymorphisms of the apolipoprotein genes to study the role of genetic variation in the determination of serum lipid levels; Hypertension and the genetics of red cell membrane abnormalities; The molecular genetics of diabetes mellitus; Searching for major genes for psychiatric disorders; The molecular genetics of HLA-related disorders; The human genome sequence and the analysis of multifactorial traits Gene therapy: efforts at developing large animal models for autologous bone marrow transplant and gene transfer with retroviral vectorsImplications of genetic research for control measures; Final general discussion; Chairman's summing-up; Index of contributors; Subject index |
| Record Nr. | UNINA-9910144748203321 |
| Chichester ; ; New York, : Wiley, 1987 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
