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Organic Cation Transporters : Integration of Physiology, Pathology, and Pharmacology / / edited by Giuliano Ciarimboli, Sophie Gautron, Eberhard Schlatter
| Organic Cation Transporters : Integration of Physiology, Pathology, and Pharmacology / / edited by Giuliano Ciarimboli, Sophie Gautron, Eberhard Schlatter |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (276 p.) |
| Disciplina | 610 |
| Soggetto topico |
Human physiology
Pharmacology Pathology Human Physiology Pharmacology/Toxicology |
| ISBN | 3-319-23793-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction to the cellular transport of organic cations -- Functional properties of organic cation transporter OCT1, binding of substrates and inhibitors, and presumed transport mechanism -- Pharmacological and toxicological significance of the organic cation transporters OCT and MATE: Drug disposition, interaction and toxicity -- Genetic variability in organic cation transporters: pathophysiological manifestations and consequences for drug pharmacokinetics and efficacy -- Physiological and pathological regulation of transporters for organic cations -- Endocrine and metabolic regulation of transporters for organic cations -- Organic cation transporters (OCTs) as modulators of behavior and mood -- Organic cation transporters as modulators of neurodegeneration and neuroprotection -- Translational relevance of animal models for the study of organic cation transporter function -- Role of transporters for organic cations in plants for environmental cycling of pharmaceutical residues. |
| Record Nr. | UNINA-9910253882003321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Physiology, Biochemistry, and Pharmacology of Transporters for Organic Cations
| Physiology, Biochemistry, and Pharmacology of Transporters for Organic Cations |
| Autore | Ciarimboli Giuliano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (248 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
anticholinergics
antidepressant-like activity Baricitinib bile acids chronic kidney disease chronic lung diseases chronoamperometry cisplatin nephrotoxicity drug disposition drug excretion drug transport drug transporters drug uptake drug-induced kidney injury drugs endogenous metabolism forced swim test functional subgroups gene ontology genetic polymorphisms gut microbiome hepatotoxicity human pathology atlas interorgan communication isoflurane ketamine kidney kidneys lung epithelium Malpighian tubule MATE MATE1 n/a nephrotoxicity Nuclear receptor OCT OCT1 organic anion transporter organic cation transporter organic cation transporters organic cations organic transporters pesticides plasma membrane monoamine transporter PPAR-alpha pulmonary drug delivery RA regulation remote sensing and signaling Remote Sensing and Signaling Theory renal excretion serotonin clearance serotonin transporter SLC22 SLC22A1 SLC22A1-5 SLC22A15 SLC22A16 SLC22A18 solute carrier solute carrier (SLC) family solute carrier 22 (SLC22) species differences tail suspension test TCGA Tofacitinib transport transporters trospium β2-agonists |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557346203321 |
Ciarimboli Giuliano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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