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Next generation sequencing in cancer research . Volume 1 Decoding the cancer genome / / Wei Wu, Hani Choudhry, editors
| Next generation sequencing in cancer research . Volume 1 Decoding the cancer genome / / Wei Wu, Hani Choudhry, editors |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | New York, : Springer Science, 2013 |
| Descrizione fisica | 1 online resource (383 p.) |
| Disciplina |
570285
599935 610 611.01816 |
| Altri autori (Persone) |
WuWei
ChoudhryHani |
| Soggetto topico |
Cancer - Genetic aspects
Gene mapping |
| ISBN | 1-4614-7645-3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction: next generation sequencing technology and cancer research -- The majority of total nuclear-encoded non-ribosomal RNA in a human cell is ‘dark matter’ unannotated RNA -- Total RNA-seq of breast cancer in hypoxia -- Altered antisense-to-sense transcript ratios in breast cancer -- Identification of piRNAs in Hela cells by massive parallel sequencing -- Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia -- Whole-Exome Sequencing Identifies FAM20A Mutations as a Cause of Amelogenesis Imperfecta and Gingival Hyperplasia Syndrome -- Whole-exome sequencing in CIC and IDH1/2 contributing to human oligodendroglioma -- Genetic and structural variation in the gastric cancer kinome revealed through targeted deep sequencing -- Tumour evolution inferred by single-cell sequencing -- Characterization of the single-cell transcriptional landscape by highly multiplex RNA-seq -- Tracing the derivation of embryonic stem cells from the inner cell mass by single-cell RNASeq analysis -- Whole genome DNA methylation analysis based on high throughput sequencing technology -- Comparative methylome analysis of benign and malignant peripheral nerve sheath tumors -- High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq -- MicroRNA transfection and AGO-bound CLIP-seq data sets reveal distinct determinants of miRNA action -- Genome-wide identification of polycomb-associated RNAs by RIP-seq -- Single-molecule sequencing: sequence methods to enable accurate quantisation -- Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells -- Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA -- The genome information process for cancer research: the challenge and perspective -- Index. |
| Record Nr. | UNINA-9910739439803321 |
| New York, : Springer Science, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Next Generation Sequencing in Cancer Research, Volume 2 : From Basepairs to Bedsides / / edited by Wei Wu, Hani Choudhry
| Next Generation Sequencing in Cancer Research, Volume 2 : From Basepairs to Bedsides / / edited by Wei Wu, Hani Choudhry |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (500 p.) |
| Disciplina |
570285
599935 610 611.01816 614.5999 |
| Soggetto topico |
Cancer - Research
Human genetics Bioinformatics Cancer Research Human Genetics |
| ISBN | 3-319-15811-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Single-cell next Generation Sequencing and Its Applications in Cancer Biology -- Utility of Next Generation Sequencing in Cancer Drug Development and Clinical Trials -- Next-Generation Sequencing in the Era of Cancer-Targeted Therapies: Towards the Personalised Medicine -- Mutational Similarities Across Cancers: Implications for Research, Diagnostics and Personalized Therapy Design -- Standardized Decision Support in NGS Reports of Somatic Cancer Variants -- Clinical Considerations in the Conduct of Cancer Next Generation Sequencing Testing and Genetic Counselling -- Next Generation Sequencing for Cancer Biomarker Discovery -- Validation and Implementation of Next Generation Sequencing Technologies in a Clinical Molecular Diagnostic Laboratory -- Next Generation Sequencing Technologies and Formalin Fixed Paraffin Embedded Tissue: Application to Clinical Cancer Research -- Applications of NGS to Screen FFPE Tumours for Detecting Fusion Transcripts -- Clinical Application of Next-Generation Sequencing of Formalin-Fixed Paraffin-Embedded Tumors -- ChIP-BS-Sequencing in Cancer Epigenomics -- Integrative Analysis Identifies Transcription Factor-DNA Methylation Relationships and Introduces New Avenues for Translating Cancer Epigenetics Into the Clinic -- Differential Methylation Analysis with Next-Generation Sequencing -- Performance Comparison and Data Analysis Strategies for MicroRNA Profiling in Cancer Research -- Small RNA Sequencing for Squamous Cell Carcinoma Research -- Exome Capture and Capturing Technologies in Cancer Research -- The Landscape of DNA Virus Associations Across Human Malignant Cancers -- Using Next Generation Sequencing to Reveal Patterns of Chromosomal Alterations in Oral Verrucous Carcinoma -- Vironomics: The Study of Viral Genomics in Human Cancer and Disease -- Molecular Typing of Lung Adenocarcinoma on Cytological Samples in the Next Generation Sequencing Era -- Whole Genome/Exome Sequencing in Acute Leukemia: From Research to Clinics -- Next Generation Sequencing Applications in Head and Neck Oncology -- CIC Mutation in Brain Tumor -- Isocitrate Dehydrogenase (IDH) Mutation in Gliomas -- Utilization of Multigene Panels in Hereditary Cancer Predisposition Testing. |
| Record Nr. | UNINA-9910298296903321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||