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Contemporary Biostatistics with Biopharmaceutical Applications / / edited by Lanju Zhang, Ding-Geng (Din) Chen, Hongmei Jiang, Gang Li, Hui Quan
Contemporary Biostatistics with Biopharmaceutical Applications / / edited by Lanju Zhang, Ding-Geng (Din) Chen, Hongmei Jiang, Gang Li, Hui Quan
Edizione [1st ed. 2019.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019
Descrizione fisica 1 online resource (339 pages)
Disciplina 610.727
519.5
Collana ICSA Book Series in Statistics
Soggetto topico Statistics 
Biostatistics
Pharmaceutical technology
Statistics for Life Sciences, Medicine, Health Sciences
Statistical Theory and Methods
Pharmaceutical Sciences/Technology
ISBN 3-030-15310-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Part I Biostatistical Methodology -- Dimension Reduction in High Dimensional Multivariate Time Series Analysis -- Multi-Panel Kendall Plot Applied to Measuring Dependence -- Flexible Optimal Design Strategies -- A Multivariate Spatial Modelling Approach with Nonparametric Cross-covariogram -- A Deterministic Global Optimization Method for Variational Inference -- Part II Statistical Genetics and Bioinformatics -- Subgroup identification with latent Dirichlet allocation -- Dictionary learning based genotype imputation to improve power for association testing -- Integrating Transcriptional Time Lag Information into Gene Regulatory Network Construction -- Optimal experimental designs for fMRI when the model matrix is uncertain -- On Exact and Approximate Distributions of K-homopolymer for iid and Markov Dependent DNA Sequences -- Part III Regulatory Statistics -- Utilizing Seamless Adaptive Designs for NASH Clinical Trials -- A Bayesian Non-inferiority Design with Companion Constancy Test in Active Controlled Trials -- A Study Design for Utilizing External Data to Augment the Control in a Randomized Controlled Trial -- Some thoughts in designing a Bayesian study: From a statistical reviewer’s perspective -- On Weighted Performance Goals in Medical Device Single-Arm Clinical Studies -- Part IV Biopharmaceutical Research and Applications.-Current Status Data in the Presence of a Terminal Event -- Seamless Phase 2/3 Study Design with an Oncology Example -- A Bayesian meta-analysis method for estimating risk difference of rare events -- Comparison of multi-arm multi-stage design and adaptive randomization in platform clinical trials -- A Calibrated Power Prior Approach to Borrow Information from Historical Data with Application -- A Gatekeeping Test in a Group Sequential Design with Multiple Interim Looks -- Application of Bayesian Methods in Oncology Dose Escalation Studies with Late Onset Toxicity -- Bayesian hierarchical model estimation and comparison of immunogenicity assay cut-points.-Inference for Two-Stage Dynamic Treatment Regimes in the Presence of Drop -- Comparison of different approaches for dynamic prediction of survival using longitudinal data -- Update on progress of ASA Biopharm Safety Monitoring Working Group -- Options for implementing pattern-mixture-based sensitivity analyses.
Record Nr. UNINA-9910349323603321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Innovative Statistical Methods for Public Health Data / / edited by Ding-Geng (Din) Chen, Jeffrey Wilson
Innovative Statistical Methods for Public Health Data / / edited by Ding-Geng (Din) Chen, Jeffrey Wilson
Edizione [1st ed. 2015.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015
Descrizione fisica 1 online resource (354 p.)
Disciplina 362.1015195
Collana ICSA Book Series in Statistics
Soggetto topico Biometry
Public health
Medicine - Research
Biology - Research
Biostatistics
Public Health
Biomedical Research
ISBN 3-319-18536-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Part 1: Modelling Clustered Data -- Methods for Analyzing Secondary Outcomes in Public Health Case Control Studies -- Controlling for Population Density Using Clustering and Data Weighting Techniques When Examining Social Health and Welfare Problems -- On the Inference of Partially Correlated Data with Applications to Public Health Issues -- Modeling Time-Dependent Covariates in Longitudinal Data Analyses -- Solving Probabilistic Discrete Event Systems with Moore-Penrose Generalized Inverse Matrix Method to Extract Longitudinal Characteristics from Cross-Sectional Survey Data -- Part II: Modelling Incomplete or Missing Data -- On the Effects of Structural Zeros in Regression Models -- Modeling Based on Progressively Type-I Interval Censored Sample -- Techniques for Analyzing Incomplete Data in Public Health Research -- A Continuous Latent Factor Model for Non-ignorable Missing Data -- Part III: Healthcare Research Models -- Health Surveillance -- Standardization and Decomposition Analysis: A Useful Analytical Method for Outcome Difference, Inequality and Disparity Studies -- Cusp Catastrophe Modeling in Medical and Health Research -- On Ranked Set Sampling Variation and its Applications to Public Health Research -- Weighted Multiple Testing Correction for Correlated Endpoints in Survival Data -- Meta-analytic Methods for Public Health Research.
Record Nr. UNINA-9910299767103321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Statistical Causal Inferences and Their Applications in Public Health Research / / edited by Hua He, Pan Wu, Ding-Geng (Din) Chen
Statistical Causal Inferences and Their Applications in Public Health Research / / edited by Hua He, Pan Wu, Ding-Geng (Din) Chen
Edizione [1st ed. 2016.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
Descrizione fisica 1 online resource (XV, 321 p. 24 illus., 11 illus. in color.)
Disciplina 519.5
Collana ICSA Book Series in Statistics
Soggetto topico Statistics 
Biostatistics
Public health
Statistics for Life Sciences, Medicine, Health Sciences
Public Health
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Part I. Overview -- 1. Causal Inference – A Statistical Paradigm for Inferring Causality -- Part II. Propensity Score Method for Causal Inference -- 2. Overview of Propensity Score Methods -- 3. Sufficient Covariate, Propensity Variable and Doubly Robust Estimation -- 4. A Robustness Index of Propensity Score Estimation to Uncontrolled Confounders -- 5. Missing Confounder Data in Propensity Score Methods for Causal Inference -- 6. Propensity Score Modeling & Evaluation -- 7. Overcoming the Computing Barriers in Statistical Causal Inference -- Part III. Causal Inference in Randomized Clinical Studies -- 8. Semiparametric Theory and Empirical Processes in Causal Inference -- 9. Structural Nested Models for Cluster-Randomized Trials -- 10. Causal Models for Randomized Trials with Continuous Compliance -- 11. Causal Ensembles for Evaluating the Effect of Delayed Switch to Second-line Antiretroviral Regimens -- 12. Structural Functional Response Models for Complex Intervention Trials -- Part IV. Structural Equation Models for Mediation Analysis -- 13.Identification of Causal Mediation Models with An Unobserved Pre-treatment Confounder -- 14. A Comparison of Potential Outcome Approaches for Assessing Causal Mediation -- 15. Causal Mediation Analysis Using Structure Equation Models. .
Record Nr. UNINA-9910148857003321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Statistical Modeling for Degradation Data / / edited by Ding-Geng (Din) Chen, Yuhlong Lio, Hon Keung Tony Ng, Tzong-Ru Tsai
Statistical Modeling for Degradation Data / / edited by Ding-Geng (Din) Chen, Yuhlong Lio, Hon Keung Tony Ng, Tzong-Ru Tsai
Edizione [1st ed. 2017.]
Pubbl/distr/stampa Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017
Descrizione fisica 1 online resource (XVIII, 376 p. 109 illus., 67 illus. in color.)
Disciplina 519.5
Collana ICSA Book Series in Statistics
Soggetto topico Statistics 
Statistical Theory and Methods
Statistics for Business, Management, Economics, Finance, Insurance
ISBN 981-10-5194-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto I. Review and Theoretical Framework -- Chapter 1: Stochastic Accelerated Degradation Models Based on a Generalized Cumu-lative Damage Approach -- Chapter 2: Hierarchical Bayesian Change-Point Analysis for Nonlinear Degradation Data -- Chapter 3: Degradation Modeling, Analysis, and Applications on Residual Life Predic-tion -- Chapter 4: On Some Shock Models with Poisson and Generalized Poisson Shock Processes -- Chapter 5: Degradation Based Reliability Modeling and Assessment of Complex Systems in Dynamic Environments -- Chapter 6: A Survey of the Modeling and Applications on Non-Destructive and De-structive Degradation Tests -- II. Modeling and Experimental Designs -- Chapter 7: Degradation Test Plan for a Nonlinear Random-Coefficients Model -- Chapter 8: Optimal Designs for LED Degradation Modeling -- Chapter 9: Gamma Degradation Models: Inferences and Optimal Designs -- Chapter 10: Model Misspecification analysis of Inverse Gaussian and Gamma Degrada-tion Processes -- III. Applications -- Chapter 11: Practical Application of Fréchet Shock-Degradation Models for System Failures -- Chapter 12: Statistical Methods for Thermal Index Estimation Based on Accelerated Destructive Degradation Test Data -- Chapter 13: Inference on Remaining Useful Life Under Gamma Degradation Models with Random effects.-- Chapter 14: ADDT: An R Package for Analysis of Accelerated Destructive Degradation Test Data -- Chapter 15: Modeling and Inference of CD4 Data. .
Record Nr. UNINA-9910254306703321
Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Statistical Modeling in Biomedical Research [[electronic resource] ] : Contemporary Topics and Voices in the Field / / edited by Yichuan Zhao, Ding-Geng (Din) Chen
Statistical Modeling in Biomedical Research [[electronic resource] ] : Contemporary Topics and Voices in the Field / / edited by Yichuan Zhao, Ding-Geng (Din) Chen
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
Descrizione fisica 1 online resource (XVIII, 491 p. 107 illus., 79 illus. in color.)
Disciplina 570.15195
Collana Emerging Topics in Statistics and Biostatistics
Soggetto topico Statistics 
Biostatistics
Big data
Data mining
Statistics for Life Sciences, Medicine, Health Sciences
Big Data/Analytics
Data Mining and Knowledge Discovery
ISBN 3-030-33416-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface -- Part I: Next Generation Sequence Data Analysis -- 1. Modeling Species Specific Gene Expression Across Multiple Regions in the Brain -- 2. Classification of EEG Motion Artifact Signals Using Spatial ICA -- 3. Weighted K-means Clustering with Observation Weight for Single-cell Epigenomic Data -- 4. Discrete Multiple Testing in Detecting Differential Methylation Using Sequencing Data -- Part II: Deep Learning, Precision Medicine and Applications -- 5. Prediction of Functional Markers of Mass Cytometry Data via Deep Learning -- 6. Building Health Application Recommender System Using Partially Penalized Regression -- 7. Hierarchical Continuous Time Hidden Markov Model, with Application in Zero-Inflated Accelerometer Data -- Part III: Large Scale Data Analysis and its Applications -- 8. Privacy Preserving Feature Selection Via Voted Wrapper Method For Horizontally Distributed Medical Data -- 9. Improving Maize Trait through Modifying Combination of Genes -- 10. Molecular Basis of Food Classification in Traditional Chinese Medicine -- 11. Discovery Among Binary Biomarkers in Heterogeneous Populations -- Part IV: Biomedical Research and the Modelling -- 12. Heat Kernel Smoothing on Manifolds and Its Application to Hyoid Bone Growth Modeling -- 13. Optimal Projections in the Distance-Based Statistical Methods -- 14. Kernel Tests for One, Two, and K-Sample Goodness-Of-Fit: State of the Art and Implementation Considerations -- 15. Hierarchical Modeling of the Effect of Pre-exposure Prophylaxis on HIV in the US -- 16. Mathematical Model of Mouse Ventricular Myocytes Overexpressing Adenylyl Cyclase Type 5 -- Part V: Survival Analysis with Complex Data Structure and its Applications -- 17. Non-Parametric Maximum Likelihood Estimator for Case-Cohort and Nested Case-Control Designs with Competing Risks Data -- Authors: Jie-Huei Wang, Chun-Hao Pan, Yi-Hau Chen and I-Shou Chang -- 18. Variable Selection in Partially Linear Proportional Hazards Model with Grouped Covariates and a Diverging Number of Parameters -- 19. Inference of Transition Probabilities in Multi-state Models using Adaptive Inverse Probability Censoring Weighting Technique.
Record Nr. UNISA-996418264403316
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
Materiale a stampa
Lo trovi qui: Univ. di Salerno
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Statistical Modeling in Biomedical Research : Contemporary Topics and Voices in the Field / / edited by Yichuan Zhao, Ding-Geng (Din) Chen
Statistical Modeling in Biomedical Research : Contemporary Topics and Voices in the Field / / edited by Yichuan Zhao, Ding-Geng (Din) Chen
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
Descrizione fisica 1 online resource (XVIII, 491 p. 107 illus., 79 illus. in color.)
Disciplina 570.15195
Collana Emerging Topics in Statistics and Biostatistics
Soggetto topico Biometry
Quantitative research
Data mining
Biostatistics
Data Analysis and Big Data
Data Mining and Knowledge Discovery
ISBN 3-030-33416-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface -- Part I: Next Generation Sequence Data Analysis -- 1. Modeling Species Specific Gene Expression Across Multiple Regions in the Brain -- 2. Classification of EEG Motion Artifact Signals Using Spatial ICA -- 3. Weighted K-means Clustering with Observation Weight for Single-cell Epigenomic Data -- 4. Discrete Multiple Testing in Detecting Differential Methylation Using Sequencing Data -- Part II: Deep Learning, Precision Medicine and Applications -- 5. Prediction of Functional Markers of Mass Cytometry Data via Deep Learning -- 6. Building Health Application Recommender System Using Partially Penalized Regression -- 7. Hierarchical Continuous Time Hidden Markov Model, with Application in Zero-Inflated Accelerometer Data -- Part III: Large Scale Data Analysis and its Applications -- 8. Privacy Preserving Feature Selection Via Voted Wrapper Method For Horizontally Distributed Medical Data -- 9. Improving Maize Trait through Modifying Combination of Genes -- 10. Molecular Basis of Food Classification in Traditional Chinese Medicine -- 11. Discovery Among Binary Biomarkers in Heterogeneous Populations -- Part IV: Biomedical Research and the Modelling -- 12. Heat Kernel Smoothing on Manifolds and Its Application to Hyoid Bone Growth Modeling -- 13. Optimal Projections in the Distance-Based Statistical Methods -- 14. Kernel Tests for One, Two, and K-Sample Goodness-Of-Fit: State of the Art and Implementation Considerations -- 15. Hierarchical Modeling of the Effect of Pre-exposure Prophylaxis on HIV in the US -- 16. Mathematical Model of Mouse Ventricular Myocytes Overexpressing Adenylyl Cyclase Type 5 -- Part V: Survival Analysis with Complex Data Structure and its Applications -- 17. Non-Parametric Maximum Likelihood Estimator for Case-Cohort and Nested Case-Control Designs with Competing Risks Data -- Authors: Jie-Huei Wang, Chun-Hao Pan, Yi-Hau Chen and I-Shou Chang -- 18. Variable Selection in Partially Linear Proportional Hazards Model with Grouped Covariates and a Diverging Number of Parameters -- 19. Inference of Transition Probabilities in Multi-state Models using Adaptive Inverse Probability Censoring Weighting Technique.
Record Nr. UNINA-9910483548903321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui