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Advances in Cancer Treatment : From Systemic Chemotherapy to Targeted Therapy / / by Iago Dillion Lima Cavalcanti, José Cleberson Santos Soares
Advances in Cancer Treatment : From Systemic Chemotherapy to Targeted Therapy / / by Iago Dillion Lima Cavalcanti, José Cleberson Santos Soares
Autore Cavalcanti Iago Dillion Lima
Edizione [1st ed. 2021.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021
Descrizione fisica 1 online resource (VIII, 109 p. 27 illus., 25 illus. in color.)
Disciplina 616.994
Soggetto topico Oncology
Internal medicine
Pharmacy
Cancer—Treatment
Tumor markers
Cancer
Nanomedicine
Internal Medicine
Cancer Therapy
Tumour Biomarkers
Cancer Nanotechnology
Oncologia
Terapèutica
Fisiologia patològica
Nanomedicina
Soggetto genere / forma Llibres electrònics
ISBN 3-030-68334-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction -- Cancer: concepts and epidemiology -- A brief history of cancer -- What is Cancer? -- Cancer Epidemiology -- Cancer development and immunology -- Cell cycle -- Cell cycle control: the function of cyclins -- Cancer triggering agents -- Proto-oncogenes -- Tumor suppressor genes -- Development of tumor mass -- Cancer Immunology -- Discovery of tumor markers -- Cancer diagnosis -- Impact of the discovery of tumor markers -- Main tumor markers for cancer diagnosis -- Alpha-fetoprotein (AFP) -- Human Chorionic Gonadotropin (β-HCG) -- Mucin-like cancer-associated antigen (MCA) -- CA 15.3 -- Carcinoembryonic antigen (CEA) -- Bladder tumor antigen (BTA) -- Telomerase -- Nuclear matrix protein (NMP 22) -- Cyfra 21.1 -- Prostatic acid phosphatase (PAP) -- Prostate-specific antigen (PSA) -- CA 125 -- CA 19.9 -- p53 -- CA 72.4 -- K-ras -- HER2 -- Cancer staging -- Conventional cancer treatment -- Therapeutic modalities of cancer -- Surgery -- Radiotherapy -- Antineoplastic chemotherapy -- Classification of antineoplastic agents by cycle -- Specific cycle antineoplastics -- Nonspecific antineoplastic agents -- Classification of antineoplastic agents by chemical structure and function -- Alkylating agents -- Antimetabolites -- Plant-derived antineoplastics -- Antitumor antibiotics -- Chemotherapy toxicity -- Hematological toxicity -- Liver toxicity -- Cardiac toxicity -- Anthracyclines -- Fluoropyrimidine -- Taxanes -- Pulmonary toxicity -- Neurological toxicity -- Renal toxicity -- Gastrointestinal toxicity -- Metabolic changes -- Targeted therapies in cancer treatment -- Overexpressed receptors on tumor cells -- Immunotherapy -- Monoclonal antibodies -- Types of monoclonal antibodies -- Side effects of monoclonal antibodies -- Checkpoint Inhibitors -- Side effects of checkpoint inhibitors -- Cancer Vaccines -- Vaccines in cancer prevention -- Vaccines for the treatment of cancer -- Non-specific immunotherapies -- Tyrosine kinase inhibitors -- Imatinib -- Gefitinib -- Erlotinib -- Sorafenib -- Dasatinib -- Nilotinib -- Lapatinib -- Adverse events of tyrosine kinase inhibitors -- Conventional chemotherapy vs. targeted therapy -- Differences between conventional chemotherapy and targeted therapy -- Risks and benefits of conventional chemotherapy compared to targeted therapy -- Eligibility criteria for the indication of the targeted therapy -- Side effects of targeted therapy -- Can targeted therapy replace conventional chemotherapy? -- Targeted therapy associated with conventional chemotherapy -- Pharmaceutical nanotechnology applied to cancer -- Pharmaceutical nanotechnology -- Classification of nanosystems -- Liposomes -- Micelles -- Polymeric nanoparticles -- Solid lipid nanoparticles -- Magnetic nanoparticles -- Metal nanoparticles -- Main functions of nanosystems in cancer -- Pharmaceutical nanotechnology in cancer diagnosis -- Pharmaceutical nanotechnology for cancer treatment.
Record Nr. UNINA-9910484989203321
Cavalcanti Iago Dillion Lima  
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Chemotherapy protocols and infusion sequence : schedule considerations in cancer treatment / / Iago Dillion Lima Cavalcanti
Chemotherapy protocols and infusion sequence : schedule considerations in cancer treatment / / Iago Dillion Lima Cavalcanti
Autore Cavalcanti Iago Dillion Lima
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2022]
Descrizione fisica 1 online resource (330 pages)
Disciplina 636.80896994
Soggetto topico Cancer - Chemotherapy
Infusion therapy
ISBN 9783031108396
9783031108389
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Preface -- Contents -- Chapter 1: Polypharmacy in Cancer Therapy -- 1.1 Polypharmacy: Challenges in the Treatment of Chronic Diseases -- 1.2 Scenario of Polypharmacy in Cancer Treatment -- 1.3 Drug Interactions -- 1.3.1 Pharmacodynamic Interactions -- 1.3.2 Pharmacokinetic Interactions -- 1.4 Advantages in Drug Association -- 1.5 Risks of Polypharmacy -- References -- Chapter 2: Combined Therapy for the Treatment of Cancer -- 2.1 Anticancer Therapy -- 2.2 Combination Therapy in Cancer -- 2.2.1 Challenges in Combination Therapy -- 2.3 Toxicity of Combination Therapy for Cancer Treatment -- 2.3.1 Toxicity in the Treatment of Breast Cancer -- 2.3.2 Toxicity in the Treatment of Lung Cancer -- 2.3.3 Toxicity in the Treatment of Colorectal Cancer -- 2.3.4 Toxicity in the Treatment of Prostate Cancer -- 2.3.5 Toxicity in the Treatment of Cervical Cancer -- 2.3.6 Toxicity in the Treatment of Head and Neck Cancer -- 2.3.7 Toxicity in the Treatment of Lymphomas -- References -- Chapter 3: Importance of the Infusion Order in the Treatment of Cancer -- 3.1 Drug Infusion Therapy -- 3.1.1 Types of Infusion According to Administration Time -- 3.2 Dilution of Drugs and Their Stability -- 3.3 Risks of Chemotherapy Infusion -- 3.3.1 Drug Extravasation -- 3.3.1.1 Irritating Antineoplastics -- 3.3.1.2 Vesicant Antineoplastics -- 3.4 Concept and Importance of Infusion Order -- 3.4.1 Factors That May Influence in the Order of Infusion of Antineoplastic Agents -- References -- Chapter 4: Chemotherapeutic Protocols for the Treatment of Breast Cancer -- 4.1 Breast Cancer: Epidemiology -- 4.2 Pathophysiology of Breast Cancer -- 4.3 Molecular Subtypes of Breast Cancer -- 4.4 Breast Cancer Treatment Modalities -- 4.5 Adjuvant Chemotherapy -- 4.5.1 AC Protocol (Doxorubicin and Cyclophosphamide).
4.5.2 ACT, T-AC, or AC-T Protocol (Doxorubicin, Cyclophosphamide, and Paclitaxel) -- 4.5.3 ACTT Protocol (Doxorubicin, Cyclophosphamide, Paclitaxel, and Trastuzumab) -- 4.5.4 CMF Protocol (Cyclophosphamide, Methotrexate, and 5-Fluorouracil) -- 4.5.5 FAC Protocol (5-Fluorouracil, Doxorubicin, and Cyclophosphamide) -- 4.5.6 FEC Protocol (5-Fluorouracil, Epirubicin, and Cyclophosphamide) -- 4.5.7 FEC-D Protocol (5-Fluorouracil, Epirubicin, Cyclophosphamide, and Docetaxel) -- 4.5.8 FEC-DT Protocol (5-Fluorouracil, Epirubicin, Cyclophosphamide, Docetaxel, and Trastuzumab) -- 4.5.9 DAC (Docetaxel, Doxorubicin, and Cyclophosphamide) and DC (Docetaxel and Cyclophosphamide) Protocols -- 4.5.10 TDC Protocol (Trastuzumab, Docetaxel, and Cyclophosphamide) -- 4.5.11 DCARBT Protocol (Docetaxel, Carboplatin, and Trastuzumab) -- 4.6 Chemotherapy in Locally Advanced Breast Cancer -- 4.6.1 AC-DT Protocol (Doxorubicin, Cyclophosphamide, Docetaxel, and Trastuzumab) -- 4.6.2 CT-AC Protocol (Carboplatin, Paclitaxel, Doxorubicin, and Cyclophosphamide) -- 4.7 Chemotherapy in Advanced Breast Cancer -- 4.7.1 GEMD Protocol (Gemcitabine and Docetaxel) -- 4.7.2 GEMP Protocol (Gemcitabine and Cisplatin) -- 4.7.3 GEMT Protocol (Gemcitabine and Paclitaxel) -- 4.7.4 PTRAD Protocol (Pertuzumab, Trastuzumab, and Docetaxel) -- 4.7.5 PTRAT Protocol (Pertuzumab, Trastuzumab, and Paclitaxel) -- 4.7.6 TRVIN Protocol (Trastuzumab and Vinorelbine) -- References -- Chapter 5: Chemotherapeutic Protocols for the Treatment of Gastrointestinal Tract Cancer -- 5.1 Epidemiological Profile of Cancers of the Gastrointestinal Tract -- 5.2 Pathophysiology of Colorectal Cancer -- 5.2.1 Adjuvant Chemotherapy for the Treatment of Resectable Colorectal Cancer -- 5.2.1.1 CAPOX Protocol (Oxaliplatin and Capecitabine) -- 5.2.1.2 FL Protocol (5-Fluorouracil and Leucovorin).
5.2.1.3 FOLFOX Protocol (Oxaliplatin, Leucovorin, 5-Fluorouracil, and 5-Fluorouracil in Continuous Infusion) -- 5.2.1.4 RALOX Protocol (Oxaliplatin and Raltitrexed) -- 5.2.2 Chemotherapy for the Treatment of Advanced Unresectable Colorectal Cancer -- 5.2.2.1 CAPB Protocol (Capecitabine and Bevacizumab) -- 5.2.2.2 CETIR Protocol (Cetuximab and Irinotecan) -- 5.2.2.3 FOLFIRI Protocol (Irinotecan, Leucovorin, 5-Fluorouracil, and 5-Fluorouracil in Continuous Infusion) -- 5.2.2.4 CAPIRI Protocol (Capecitabine and Irinotecan) -- 5.2.2.5 CAPIRIB Protocol (Capecitabine, Irinotecan, and Bevacizumab) -- 5.2.2.6 CAPOXB Protocol (Oxaliplatin, Bevacizumab, and Capecitabine) -- 5.2.2.7 FOLFIRIB Protocol (5-Fluorouracil, 5-Fluorouracil in Continuous Infusion, Leucovorin, Irinotecan, and Bevacizumab) -- 5.2.2.8 FOLFIRIPAN Protocol (5-Fluorouracil, Leucovorin, Irinotecan, and Panitumumab) -- 5.2.2.9 FOLFOXB Protocol (Oxaliplatin, Leucovorin, 5-Fluorouracil, 5-Fluorouracil in Continuous Infusion, and Bevacizumab) -- 5.2.2.10 FOLFOXPAN Protocol (Oxaliplatin, 5-Fluorouracil, 5-Fluorouracil in Continuous Infusion, Leucovorin, and Panitumumab) -- 5.3 Pathophysiology of Esophageal and Stomach Cancers -- 5.3.1 Chemotherapy for the Treatment of Esophageal and Stomach Cancer -- 5.3.1.1 FOLFOXT Protocol (Oxaliplatin, 5-Fluorouracil, 5-Fluorouracil in Continuous Infusion, Leucovorin, and Trastuzumab) -- 5.3.1.2 FLOT Protocol (Oxaliplatin, 5-Fluorouracil, Leucovorin, and Docetaxel) -- 5.3.1.3 CTRT Protocol (Carboplatin, Paclitaxel, and Radiotherapy) -- 5.3.1.4 FUC Protocol (5-Fluorouracil and Cisplatin) -- 5.3.1.5 CCAPRT Protocol (Cisplatin, Capecitabine, and Radiotherapy) -- 5.3.1.6 CCAPT Protocol (Cisplatin, Capecitabine, and Trastuzumab) -- 5.3.1.7 CFUT Protocol (Cisplatin, 5-Fluorouracil, and Trastuzumab).
5.3.1.8 CAPOXT Protocol (Capecitabine, Oxaliplatin, and Trastuzumab) -- 5.3.1.9 RAMP Protocol (Paclitaxel and Ramucirumab) -- 5.3.1.10 ECCAP Protocol (Epirubicin, Cisplatin, and Capecitabine) -- 5.4 Pathophysiology of Pancreatic, Biliary Tract, and Gallbladder Cancers -- 5.4.1 Chemotherapy for the Treatment of Pancreatic, Biliary Tract, and Gallbladder Cancers -- 5.4.1.1 GEMCIS Protocol (Gemcitabine and Cisplatin) -- 5.4.1.2 FOLFIRINOX Protocol (Irinotecan, Oxaliplatin, 5-Fluorouracil, 5-Fluorouracil in Continuous Infusion, and Leucovorin) -- 5.4.1.3 GEMCAP Protocol (Capecitabine and Gemcitabine) -- 5.4.1.4 GEMABR Protocol (Gemcitabine and Nab-Paclitaxel) -- 5.5 Pathophysiology of Liver Cancer -- 5.5.1 Chemotherapy for the Treatment of Liver Cancer -- 5.5.1.1 Nivolumab and Ipilimumab Protocol -- 5.5.1.2 Atezolizumab and Bevacizumab Protocol -- 5.6 Pathophysiology of Carcinoid and Neuroendocrine Tumors -- 5.6.1 Chemotherapy for the Treatment of Carcinoid and Neuroendocrine Tumors -- 5.6.1.1 ETCIS Protocol (Etoposide and Cisplatin) -- 5.6.1.2 DS Protocol (Doxorubicin and Streptozotocin) -- 5.7 Pathophysiology of Anal Cancer -- 5.7.1 Chemotherapy in the Treatment of Anal Cancer -- 5.7.1.1 FUMRT Protocol (5-Fluorouracil, Mitomycin C, and Radiotherapy) -- 5.7.1.2 CAPMRT Protocol (Capecitabine, Mitomycin C, and Radiotherapy) -- References -- Chapter 6: Chemotherapeutic Protocols for the Treatment of Genitourinary Cancer -- 6.1 Epidemiological Profile of Genitourinary Cancers -- 6.2 Pathophysiology of Bladder Cancer -- 6.2.1 Chemotherapy for the Treatment of Bladder Cancer -- 6.2.1.1 BCGIFN Protocol (BCG and Interferon) -- 6.2.1.2 GEMDOC Protocol (Gemcitabine and Docetaxel) -- 6.2.1.3 MVAC Protocol (Methotrexate, Vinblastine, Doxorubicin, and Cisplatin) -- 6.3 Pathophysiology of Prostate Cancer -- 6.3.1 Chemotherapy for the Treatment of Prostate Cancer.
6.4 Testicular Cancer -- 6.4.1 Chemotherapy for the Treatment of Testicular Cancer -- 6.4.1.1 BEP Protocol (Bleomycin, Etoposide, and Cisplatin) -- 6.4.1.2 VIP Protocol (Etoposide, Cisplatin, Ifosfamide, and Mesna) -- 6.4.1.3 TAXGEM Protocol (Paclitaxel and Gemcitabine) -- 6.4.1.4 TIP Protocol (Paclitaxel, Cisplatin, Ifosfamide, and Mesna) -- 6.4.1.5 VEIP Protocol (Vinblastine, Cisplatin, Ifosfamide, and Mesna) -- 6.5 Pathophysiology of Kidney Cancer -- 6.5.1 Chemotherapy for the Treatment of Kidney Cancer -- 6.5.1.1 PEMAX Protocol (Pembrolizumab and Axitinib) -- 6.5.1.2 Avelumab and Axitinib Protocol -- References -- Chapter 7: Chemotherapeutic Protocols for the Treatment of Gynecological Cancer -- 7.1 Epidemiological Profile of Gynecological Cancers -- 7.2 Pathophysiology of Ovarian Cancer -- 7.2.1 Chemotherapy for the Treatment of Epithelial Ovarian Cancer -- 7.2.1.1 CABR Protocol (Carboplatin and Abraxane) -- 7.2.1.2 CAPBEV Protocol (Carboplatin, Paclitaxel, and Bevacizumab) -- 7.2.1.3 CISP Protocol (Cisplatin and Paclitaxel) -- 7.2.1.4 CISPBEV Protocol (Cisplatin, Paclitaxel, and Bevacizumab) -- 7.2.1.5 CAD Protocol (Carboplatin and Docetaxel) -- 7.2.1.6 CAG Protocol (Carboplatin and Gemcitabine) -- 7.2.1.7 PLDC Protocol (Pegylated Liposomal Doxorubicin and Carboplatin) -- 7.2.1.8 BEVG Protocol (Bevacizumab and Gemcitabine) -- 7.2.1.9 BEVPLD Protocol (Bevacizumab and Pegylated Liposomal Doxorubicin) -- 7.2.1.10 BEVP Protocol (Bevacizumab and Paclitaxel) -- 7.2.2 Chemotherapy for the Treatment of Non-epithelial Ovarian Cancer -- 7.3 Pathophysiology of Cervical Cancer -- 7.3.1 Chemotherapy for the Treatment of Cervical Cancer -- 7.4 Pathophysiology of Endometrial Cancer -- 7.4.1 Chemotherapy for the Treatment of Endometrial Cancer -- 7.5 Pathophysiology of Gestational Trophoblastic Neoplasia.
7.5.1 Chemotherapy for the Treatment of Gestational Trophoblastic Neoplasia.
Record Nr. UNINA-9910619286503321
Cavalcanti Iago Dillion Lima  
Cham, Switzerland : , : Springer, , [2022]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui