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Decreasing the Impact of Treatment Resistance in Schizophrenia: Identifying Novel Molecular Targets/ Pathways to Increase Treatment Efficacy
Decreasing the Impact of Treatment Resistance in Schizophrenia: Identifying Novel Molecular Targets/ Pathways to Increase Treatment Efficacy
Autore Manchia Mirko
Pubbl/distr/stampa Frontiers Media SA, 2020
Descrizione fisica 1 electronic resource (177 p.)
Soggetto topico Science: general issues
Pharmacology
Soggetto non controllato omics
epigenetics
pharmacogenetics
CYP
risk prediction
microbiota
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti Decreasing the Impact of Treatment Resistance in Schizophrenia
Record Nr. UNINA-9910557214503321
Manchia Mirko  
Frontiers Media SA, 2020
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Recovery and major mental disorders / / Bernardo Carpiniello, Antonio Vita and Claudio Mencacci, editors
Recovery and major mental disorders / / Bernardo Carpiniello, Antonio Vita and Claudio Mencacci, editors
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2022]
Descrizione fisica 1 online resource (264 pages)
Disciplina 616.898
Collana Comprehensive approach to psychiatry
Soggetto topico Schizophrenia - Treatment
Affective disorders - Treatment
ISBN 3-030-98301-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Foreword -- Introductory Remarks. The Recovery Model in Mental Health -- Contents -- Part I: Recovery in Schizophrenia and Related Disorders -- 1: Dimensions and Course of Clinical Recovery in Schizophrenia and Related Disorders -- 1.1 Introduction -- 1.2 Clinical Recovery -- 1.2.1 Conceptual Heterogeneity of Clinical Recovery -- 1.2.2 Prevalence of Clinical Recovery -- 1.2.2.1 Methodological Issues -- 1.2.2.2 Data from Studies Based on Prevalent Cases -- 1.2.2.3 Data from Studies Based on Incident Cases -- 1.2.2.4 Data from Meta-analytical Studies -- 1.2.3 Time Course of Recovery -- 1.2.4 Recovery Beyond Schizophrenia -- 1.2.5 Recovery in the Elderly -- 1.3 Clinical and Personal Recovery -- 1.3.1 Personal Recovery -- Definitions, Characteristics, Processes, Stages -- 1.3.2 Clinical vs. Personal Recovery -- 1.4 Concluding Remarks -- References -- 2: Determinants of Clinical Recovery in Schizophrenia -- 2.1 Introduction -- 2.2 Cross-Sectional Assessment of Determinants of Clinical Recovery -- 2.2.1 Neurocognitive Deficits -- 2.2.2 Deficits of Functional Capacity -- 2.2.3 Deficits of Social Cognition -- 2.2.4 Negative Symptoms -- 2.2.5 Other Potential Predictors or Mediators of Clinical Recovery -- 2.3 Longitudinal Assessment of Determinants of Clinical Recovery -- 2.3.1 Neurocognitive Deficits -- 2.3.2 Deficits of Functional Capacity and Social Cognition -- 2.3.3 Negative Symptoms -- 2.4 Conclusions -- References -- 3: Personal Recovery in Schizophrenia: A Narrative Review -- 3.1 Introduction -- 3.2 From Remission to Recovery -- 3.3 How Many Types of Recovery -- 3.4 The Content of Personal Recovery -- 3.5 Consumer Models of Recovery -- 3.6 Stigma and Resilience -- 3.7 From Values to Recovery -- 3.8 A Pragmatic View About Personal Recovery -- 3.9 Conclusions -- References.
4: Personal Recovery Within Forensic Settings -- 4.1 Introduction -- 4.2 Personal Recovery -- 4.3 Forensic Settings and Practice -- 4.4 Forensic Recovery -- 4.5 Particular Issues -- 4.5.1 Ethics -- 4.5.2 Complexity, Co-morbidity and Personality Disruption -- 4.5.3 Offending Behaviour -- 4.6 Future Work and Directions -- References -- 5: Stigma and Attitude Towards Personal Recovery from Mental Illness Among Italian Mental Health Professionals -- 5.1 Introduction -- 5.2 Attitudes and Stigma Displayed by Mental Health Professionals Towards the Mentally Ill: Selected Studies Conducted in Italian Facilities -- 5.3 Assessment of Staff Knowledge and Attitudes Towards Recovery Principles -- 5.3.1 Quantitative Methods -- 5.4 Measures of Recovery Orientation in Mental Health Services -- 5.5 Italian Study of the Knowledge of and Attitudes Displayed Towards Personal Recovery from Mental Illness by Mental Health Operators -- 5.6 Conclusions -- References -- 6: Psychosocial Recovery-Oriented Interventions in Schizophrenia -- 6.1 Background -- 6.1.1 Evidence-Based Psychosocial Practices -- 6.1.2 Psychoeducation and Family Interventions -- 6.1.3 Cognitive Behavioural Therapy for Psychosis -- 6.1.4 Social Skills Training -- 6.1.5 Vocational Rehabilitation: Supported Employment and Prevocational Training -- 6.1.6 Cognitive Remediation -- 6.1.7 Social Cognitive Training -- 6.1.8 Metacognitive Training -- 6.1.9 Healthy Lifestyle Interventions and Physical Exercise -- 6.1.10 Assertive Community Treatment -- 6.1.11 Illness Self-Management Training -- 6.1.12 Integrated Interventions -- 6.1.13 Integrated Early Intervention for Psychosis -- 6.1.14 Integrated Interventions for Co-occurring Substance Use Disorder -- 6.2 Critical Issues and Future Challenges -- References.
7: Recovery from Psychosis: Emerging Definitions, Research and Select Clinical Application -- 7.1 Introduction -- 7.2 Historical Views of Outcome from Psychosis and the Emergence of the Concept of Recovery -- 7.2.1 The Challenge of Defining Recovery -- 7.2.2 Objective and Subjective Domains of Recovery -- 7.2.3 Recovery, the Self, and Metacognition -- 7.3 General Implications for Recovery-Oriented Practice -- 7.4 Four Emerging Forms of Recovery Oriented Treatments -- 7.5 Reflections, Limitations, and Future Directions -- References -- 8: Treatments and Recovery to Enhance Employment Outcomes for People with Schizophrenia and Other Major Mental Disorders: An Innovative Clinical and Organisational Model of Work Inclusion in Milan and Surrounding Area -- 8.1 Introduction -- 8.2 How to Improve Employment Outcomes for People with Schizophrenia and Other Major Mental Disorders. A Brief Introduction to the Main Models and Issues -- 8.3 Supporting Employment in an Advanced Welfare Context. Treatments, Recovery, Regulatory Changes and Methodological and Organisational Issues in the City of Milan -- 8.4 The Development of Regional Innovative Programme TR-106 Between 2009 and 2019 and Its Impact -- 8.5 Sample Description and Outcome -- 8.6 Perspectives, Critical Issues and Conclusions -- References -- 9: Recovery-Oriented Psychopharmacological Interventions in Schizophrenia -- 9.1 Introduction -- 9.1.1 Historical Aspects: From Chemical Contention to Remission and Recovery -- 9.1.2 Clinical Recovery May Not Be Patient Recovery -- 9.1.3 Psychopharmacological Interventions Among Other Factors of Recovery -- 9.1.4 How to Assess Functional Remission -- 9.1.5 The Place of Functional Remission/Recovery in Pharmacological Trials -- 9.2 The Impact of Psychopharmacological Interventions on Recovery.
9.2.1 The Positive Impact of Psychopharmacological Interventions -- 9.2.2 The Problem of Adherence -- 9.2.2.1 The Impact of Side Effects on Adherence and Well-Being -- 9.2.2.2 Using Different Pharmacological Approaches to Diminish Side Effects -- 9.2.2.3 Using Long-Acting Injectable Antipsychotics to Enhance the Potential for Recovery -- 9.2.3 Using Antipsychotic Polypharmacy to Diminish the Risk of Hospitalization -- 9.2.4 Shared Decision-Making to Improve Adherence and Empowerment -- 9.2.5 Recent Pharmacological Advances -- 9.2.5.1 Partial Agonists at the D2 Receptor -- 9.2.5.2 Anti-inflammatory Strategies -- 9.2.5.3 Other Promising Pharmacological Agents -- 9.3 Conclusion -- References -- Part II: Recovery in Mood Disorders -- 10: Predictors of Clinical Recovery in Bipolar Disorders -- 10.1 Introduction -- 10.2 Remission in Bipolar Disorders -- 10.2.1 Definition of Remission -- 10.2.2 Treatment Strategies for Remission -- 10.2.2.1 Acute Mania -- 10.2.2.2 Acute Bipolar Depression -- 10.2.2.3 Mixed States -- 10.3 From Symptomatic to Functional Recovery -- 10.3.1 Maintenance Treatment of Bipolar Disorder -- 10.3.2 Residual Symptoms -- 10.4 Functional Recovery -- 10.4.1 The Pathway to Recovery in Bipolar Disorder: Functional Remediation -- 10.5 Conclusions -- References -- 11: Psychosocial Recovery-Oriented Treatments in Bipolar Disorders -- 11.1 Psychosocial Functioning in Bipolar Disorder -- 11.2 Defining and Measuring Psychosocial Functioning -- 11.3 Variables Related with Psychosocial Functioning -- 11.4 Restoring Psychosocial Functioning -- 11.4.1 Pharmacological Interventions -- 11.4.2 Psychological Interventions -- 11.5 Preventing Functional Decline -- 11.5.1 Addressing Subthreshold Depressive Symptoms -- 11.5.2 Enhancing Cognitive Reserve -- 11.5.3 Diet and Physical Exercise -- 11.5.4 Multicomponent Programs.
11.6 Personal Recovery: Well-Being and QoL -- 11.6.1 Pharmacological Interventions -- 11.6.2 Psychological Interventions -- 11.7 Conclusions -- References -- 12: Psychopharmacological Recovery-Oriented Treatments in Bipolar Disorders -- 12.1 Introduction -- 12.2 Psychopharmacological Treatment of Bipolar Phases -- 12.2.1 Acute Mania in Bipolar Disorder -- 12.2.2 Rapid Cycling Bipolar Disorder -- 12.2.3 Bipolar Depression -- 12.2.4 Mixed States in Bipolar Disorder -- 12.3 Treatment-Resistant Bipolar Disorder (Augmentation Strategies) -- 12.4 Special Populations -- 12.4.1 Pregnancy -- 12.4.2 Breastfeeding -- 12.5 Maintenance of Bipolar Disorder -- 12.6 Prophylaxis of Bipolar Disorder -- 12.6.1 Antipsychotic Long-Acting Injections in Bipolar Disorder -- 12.7 Conclusions -- References -- 13: Dimensions and Predictors of Personal Recovery in Major Depression -- 13.1 Introduction -- 13.2 From Response to Full Functional Recovery in MDD: History of Outcome Definitions in the Treatment for MDD -- 13.3 Dimensions of Personal Recovery in Severe Mental Disorders -- 13.4 Personal Recovery in Major Depression -- 13.5 The Way Forward -- 13.6 Conclusions -- References -- 14: Recovery-Oriented Treatments in Major Depressive Disorder -- 14.1 Toward a Recovery-Oriented Model of Major Depression -- 14.2 Toward Full Functional Recovery: How to Improve Patients' Outcome with Personalized and Precision Interventions -- 14.3 Recovery-Oriented Pharmacological Treatments -- 14.4 Psychotherapies and the Role of Combination Therapies -- 14.5 Psychosocial Interventions -- 14.6 Conclusions -- References.
Record Nr. UNINA-9910734096303321
Cham, Switzerland : , : Springer, , [2022]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Violence and Mental Disorders / / edited by Bernardo Carpiniello, Antonio Vita, Claudio Mencacci
Violence and Mental Disorders / / edited by Bernardo Carpiniello, Antonio Vita, Claudio Mencacci
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
Descrizione fisica 1 online resource (296 pages)
Disciplina 616.8582
Collana Comprehensive Approach to Psychiatry
Soggetto topico Psychiatry
ISBN 3-030-33188-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Section I General aspects.-Violence as a social, clinical and forensic problem.-Biological basis of violence in mental disorders.-Epidemiology and risk factors for violence in people with mental disorders.-Section II Risk Factors, phenomenology and characteristics of violence in mental disorders.-Violence in major mental disorders -- Psychopaty, personality disorders and violence -- Substance use disorders and violence.-Violence and PTSD -- Major Neurocognitive disorders and violence.-Section III The contexts of violence.-Studying patients with severe mental disorders who act violently: Italian and European projects.-Prevalence and risk factors of violence by psychiatric acute inpatients: systematic review and meta-analysis. A 2019 Update -- Violence and mental disorders in Jails.-Violent behavior in Forensic Residential Facilities: the Italian experience after the closure of Forensic Psychiatric Hospitals.-Section IV Prevention and management of violence in mental health -- Violence Risk Assessment in mental health.-Psychoparmacology of violent behaviour among people with severe mental disorders.-Non Pharmacological approaches to violence among people with severe mental disorders.
Record Nr. UNINA-9910369959603321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui