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Fibrocytes [[electronic resource] ] : new insights into tissue repair and systemic fribrosis / / editor, Richard Bucala
| Fibrocytes [[electronic resource] ] : new insights into tissue repair and systemic fribrosis / / editor, Richard Bucala |
| Pubbl/distr/stampa | Hackensack, NJ, : World Scientific, c2007 |
| Descrizione fisica | 1 online resource (268 p.) |
| Disciplina | 612.7/5 |
| Altri autori (Persone) | BucalaRichard |
| Soggetto topico | Fibroblasts |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-281-12089-8
9786611120894 981-270-669-0 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contributors; CONTENTS; Chapter 1 Fibrocytes: Discovery of a Circulating Connective Tissue Cell Progenitor Richard Bucala; Chapter 2 Fibrocytes: Immunologic Features Jason Chesney; Chapter 3 Regulatory Pathways for Fibrocyte Differentiation Darrell Pilling and Richard H. Gomer; Chapter 4 Hematopoietic Origin of Fibrocytes Amanda C. LaRue and Makio Ogawa; Chapter 5 The Role of Fibrocytes in Post-burn Hypertrophic Scarring JianFei Wang, Yaujiong Wu, Abelardo Medina, Paul. G. Scott and Edward E. Tredget; Chapter 6 Role in Asthmatic Lung Disease Sabrina Mattoli and Matthias Schmidt
Chapter 7 Fibrocytes and Other Fibroblast/Myofibroblast Progenitors in Systemic Sclerosis Arnold E. PostlethwaiteChapter 8 Fibrocytes in Interstitial Lung Disease Brigitte N. Gomperts and Robert M. Strieter; Chapter 9 Role of Fibrocytes in Renal Fibrosis Norihiko Sakai, Takashi Wada, Kouji Matsushima and Shuichi Kaneko; Chapter 10 Role of Fibrocytes in Atherogenesis Heather Medbury; Chapter 11 Nephrogenic Systemic Fibrosis: A Prototype Fibrocyte Disease Cynthia L. Kucher and Shawn E. Cowper; Chapter 12 CD34+ Fibrocytes in Normal and Neoplastic Human Tissues Peter J Barth; Index |
| Record Nr. | UNINA-9910450689703321 |
| Hackensack, NJ, : World Scientific, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Fibrocytes [[electronic resource] ] : new insights into tissue repair and systemic fribrosis / / editor, Richard Bucala
| Fibrocytes [[electronic resource] ] : new insights into tissue repair and systemic fribrosis / / editor, Richard Bucala |
| Pubbl/distr/stampa | Hackensack, NJ, : World Scientific, c2007 |
| Descrizione fisica | 1 online resource (268 p.) |
| Disciplina | 612.7/5 |
| Altri autori (Persone) | BucalaRichard |
| Soggetto topico | Fibroblasts |
| ISBN |
1-281-12089-8
9786611120894 981-270-669-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contributors; CONTENTS; Chapter 1 Fibrocytes: Discovery of a Circulating Connective Tissue Cell Progenitor Richard Bucala; Chapter 2 Fibrocytes: Immunologic Features Jason Chesney; Chapter 3 Regulatory Pathways for Fibrocyte Differentiation Darrell Pilling and Richard H. Gomer; Chapter 4 Hematopoietic Origin of Fibrocytes Amanda C. LaRue and Makio Ogawa; Chapter 5 The Role of Fibrocytes in Post-burn Hypertrophic Scarring JianFei Wang, Yaujiong Wu, Abelardo Medina, Paul. G. Scott and Edward E. Tredget; Chapter 6 Role in Asthmatic Lung Disease Sabrina Mattoli and Matthias Schmidt
Chapter 7 Fibrocytes and Other Fibroblast/Myofibroblast Progenitors in Systemic Sclerosis Arnold E. PostlethwaiteChapter 8 Fibrocytes in Interstitial Lung Disease Brigitte N. Gomperts and Robert M. Strieter; Chapter 9 Role of Fibrocytes in Renal Fibrosis Norihiko Sakai, Takashi Wada, Kouji Matsushima and Shuichi Kaneko; Chapter 10 Role of Fibrocytes in Atherogenesis Heather Medbury; Chapter 11 Nephrogenic Systemic Fibrosis: A Prototype Fibrocyte Disease Cynthia L. Kucher and Shawn E. Cowper; Chapter 12 CD34+ Fibrocytes in Normal and Neoplastic Human Tissues Peter J Barth; Index |
| Record Nr. | UNINA-9910784046603321 |
| Hackensack, NJ, : World Scientific, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
MIF Family Cytokines in Innate Immunity and Homeostasis / / edited by Richard Bucala, Jürgen Bernhagen
| MIF Family Cytokines in Innate Immunity and Homeostasis / / edited by Richard Bucala, Jürgen Bernhagen |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (VIII, 246 p. 37 illus., 25 illus. in color.) |
| Disciplina | 572.6 |
| Collana | Progress in Inflammation Research |
| Soggetto topico |
Cytokines
Growth factors Immunology Infectious diseases Cell biology Cytokines and Growth Factors Infectious Diseases Cell Biology |
| ISBN | 3-319-52354-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | MIF and CD74-dependent Mechanisms -- HSP90-stabilized MIF in Oncogenesis and Cell Growth Control- CD74, MIF, and Breast Tumorigenesis: Insights from Recent Large-scale Tumor Genomics and Proteomics Studies -- MIF-dependent Regulation of Monocyte/Macrophage Polarization -- Advances in understanding the role of MIF in the pathogenesis of autoimmune diseases -- Role of MIF in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis -- Role of MIF in Hepatic Inflammatory Diseases and Fibrosis -- MIF and Pulmonary Disease -- MIF Mediates Pelvic Inflammation and Pain -- MIF Family Proteins in Cardiac Ischemia / Reperfusion Injury -- The MIF-CD74 Inflammatory Axis in Alphaviral Infection -- MIF in Eosinophilic Inflammation -- The Role of MIF in Parasitic Infections -- Parasite MIF Orthologs. |
| Record Nr. | UNINA-9910254650903321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The MIF handbook [[electronic resource] /] / edited by Richard Bucala
| The MIF handbook [[electronic resource] /] / edited by Richard Bucala |
| Pubbl/distr/stampa | Hackensack, NJ., : World Scientific, c2012 |
| Descrizione fisica | 1 online resource (399 p.) |
| Disciplina | 572/.696 |
| Altri autori (Persone) | BucalaRichard |
| Soggetto topico |
Cytokines
Immune response - Regulation |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-283-59367-X
9786613906120 981-4335-36-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Preface; Part I MIF Structure and Mechanism of Action; I-1 MIF, MIF Alleles, and the Regulation of the Host Response Richard Bucala; 1. Introduction; 2. MIF Gene; 3. MIF Production and Signal Transduction; 4. Innate Immunity; 5. Adaptive Immunity; 6. MIF Integrates Immune, Metabolic, and Oncogenic Responses; 7. MIF Alleles in Human Disease; 8. Therapeutic Implications and Future Directions; Acknowledgments; References; I-2 MIF and the Chemokine Axis Sandra Kraemer, Christian Weber and Jürgen Bernhagen; 1. Introduction; 2. Chemokines: Classes, Structure, Function, and Receptors
3. Structural Classification of MIF4. Nonclassical MIF Secretion and Link to Secretion of CLF Chemokines; 5. Chemokine-like Function (CLF) Chemokines and MIF as a CLF Chemokine; 6. MIF/ Chemokine Receptor Interactions and Functional Role in Inflammation and Atherogenesis; 7. Structural Basis Underlying MIF/Chemokine Receptor Interactions; 8. MIF Receptor Complexes; 9. Conclusion; 10. Acknowledgments; References; I-3 CD74, the Natural Receptor for MIF, Regulates Cell Survival in Health and Disease Idit Shachar, Maya Gordin, Sivan Cohen, Inbal Binsky, Ayelet Marom and Shirly Becker-Herman 1. Introduction2. CD74 (Invariant Chain, Ii); 3. CD74 Functions as a Chaperone for MHC Class II; 4. CD74 as a Signaling Molecule; 4.1 CD74 is a cell surface receptor that induces signaling cascades; 4.2 CD74 is subjected to regulated intramembrane proteolysis (RIP); 5. MIF Regulates B Cell Survival in a CD74-Dependent Manner; 5.1 A complex of CD74 and CD44 is essential for initiating the signaling cascade induced by MIF; 5.2 c-Met and its ligand HGF regulate mature B cell survival in a pathway induced by MIF binding to CD74/CD44 5.3 MIF induces TAp63 expression, which regulates B cell survival in a CD74-dependent manner6. MIF Is Secreted from Perivascular Bone Marrow Dendritic Cell Clusters that Regulate B Cell Survival; 7. MIF and CD74 in Tumors; 7.1 MIF and CD74 in CLL survival; 7.2 MIF and CD74 regulate CLL homing to the BM; References; I-4 Towards the MIF Interactome Jörg Klug and Andreas Meinhardt; 1. Introduction; 2. MIF Affects Degradation of Regulatory Proteins by Modulating the Ubiquitin Proteasome System; 3. Ribosomal Protein S19 as Endogenous Inhibitor of Extracellular MIF 4. Interactors Involved in MIF Redox Activity4.1. Insulin; 4.2. Hepatopoietin (HPO); 4.3. Proliferation-associated gene (PAG) protein; 4.4. p53; 4.5. Protein (NM23A) expressed in nonmetastatic cells (NM23-H1); 4.6. α1-inhibitor-3 (α1-I3); 5 Concluding Remarks; Acknowledgments; References; I-5 Structural Studies of Small Molecule Inhibitors of MIF Yoonsang Cho and Elias J. Lolis; 1. Introduction; 2. Small Molecule Structures; 3. Catalytic Site Inhibitors; 4. Covalent Inhibitors; 5. Allosteric and Mixed Inhibitors; References; Part II Regulation of MIF Expression II-1 Epigenetic Control of MIF Expression Thierry Roger, Jérôme Lugrin, Xavier C. Ding and Thierry Calandra |
| Record Nr. | UNINA-9910465480503321 |
| Hackensack, NJ., : World Scientific, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The MIF handbook [[electronic resource] /] / edited by Richard Bucala
| The MIF handbook [[electronic resource] /] / edited by Richard Bucala |
| Pubbl/distr/stampa | Hackensack, NJ., : World Scientific, c2012 |
| Descrizione fisica | 1 online resource (399 p.) |
| Disciplina | 572/.696 |
| Altri autori (Persone) | BucalaRichard |
| Soggetto topico |
Cytokines
Immune response - Regulation |
| ISBN |
1-283-59367-X
9786613906120 981-4335-36-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Preface; Part I MIF Structure and Mechanism of Action; I-1 MIF, MIF Alleles, and the Regulation of the Host Response Richard Bucala; 1. Introduction; 2. MIF Gene; 3. MIF Production and Signal Transduction; 4. Innate Immunity; 5. Adaptive Immunity; 6. MIF Integrates Immune, Metabolic, and Oncogenic Responses; 7. MIF Alleles in Human Disease; 8. Therapeutic Implications and Future Directions; Acknowledgments; References; I-2 MIF and the Chemokine Axis Sandra Kraemer, Christian Weber and Jürgen Bernhagen; 1. Introduction; 2. Chemokines: Classes, Structure, Function, and Receptors
3. Structural Classification of MIF4. Nonclassical MIF Secretion and Link to Secretion of CLF Chemokines; 5. Chemokine-like Function (CLF) Chemokines and MIF as a CLF Chemokine; 6. MIF/ Chemokine Receptor Interactions and Functional Role in Inflammation and Atherogenesis; 7. Structural Basis Underlying MIF/Chemokine Receptor Interactions; 8. MIF Receptor Complexes; 9. Conclusion; 10. Acknowledgments; References; I-3 CD74, the Natural Receptor for MIF, Regulates Cell Survival in Health and Disease Idit Shachar, Maya Gordin, Sivan Cohen, Inbal Binsky, Ayelet Marom and Shirly Becker-Herman 1. Introduction2. CD74 (Invariant Chain, Ii); 3. CD74 Functions as a Chaperone for MHC Class II; 4. CD74 as a Signaling Molecule; 4.1 CD74 is a cell surface receptor that induces signaling cascades; 4.2 CD74 is subjected to regulated intramembrane proteolysis (RIP); 5. MIF Regulates B Cell Survival in a CD74-Dependent Manner; 5.1 A complex of CD74 and CD44 is essential for initiating the signaling cascade induced by MIF; 5.2 c-Met and its ligand HGF regulate mature B cell survival in a pathway induced by MIF binding to CD74/CD44 5.3 MIF induces TAp63 expression, which regulates B cell survival in a CD74-dependent manner6. MIF Is Secreted from Perivascular Bone Marrow Dendritic Cell Clusters that Regulate B Cell Survival; 7. MIF and CD74 in Tumors; 7.1 MIF and CD74 in CLL survival; 7.2 MIF and CD74 regulate CLL homing to the BM; References; I-4 Towards the MIF Interactome Jörg Klug and Andreas Meinhardt; 1. Introduction; 2. MIF Affects Degradation of Regulatory Proteins by Modulating the Ubiquitin Proteasome System; 3. Ribosomal Protein S19 as Endogenous Inhibitor of Extracellular MIF 4. Interactors Involved in MIF Redox Activity4.1. Insulin; 4.2. Hepatopoietin (HPO); 4.3. Proliferation-associated gene (PAG) protein; 4.4. p53; 4.5. Protein (NM23A) expressed in nonmetastatic cells (NM23-H1); 4.6. α1-inhibitor-3 (α1-I3); 5 Concluding Remarks; Acknowledgments; References; I-5 Structural Studies of Small Molecule Inhibitors of MIF Yoonsang Cho and Elias J. Lolis; 1. Introduction; 2. Small Molecule Structures; 3. Catalytic Site Inhibitors; 4. Covalent Inhibitors; 5. Allosteric and Mixed Inhibitors; References; Part II Regulation of MIF Expression II-1 Epigenetic Control of MIF Expression Thierry Roger, Jérôme Lugrin, Xavier C. Ding and Thierry Calandra |
| Record Nr. | UNINA-9910792083903321 |
| Hackensack, NJ., : World Scientific, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||