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Applications of Toxicogenomics in Safety Evaluation and Risk Assessment [[electronic resource]]
| Applications of Toxicogenomics in Safety Evaluation and Risk Assessment [[electronic resource]] |
| Autore | Boverhof Darrell R |
| Pubbl/distr/stampa | Hoboken, : Wiley, 2011 |
| Descrizione fisica | 1 online resource (402 p.) |
| Disciplina |
616.042
616/.042 |
| Altri autori (Persone) | GollapudiB. Bhaskar |
| Soggetto topico |
Genetic toxicology
Health risk assessment Risk Assessment Toxicity testing Toxicogenetics Toxicology Pharmacogenetics Risk Risk Management Epidemiologic Measurements Organization and Administration Pharmacology Probability Genetics Public Health Health Occupations Statistics as Topic Biological Science Disciplines Biology Health Services Administration Environment and Public Health Natural Science Disciplines Health Care Health Care Evaluation Mechanisms Epidemiologic Methods Quality of Health Care Investigative Techniques Health Care Quality, Access, and Evaluation Health & Biological Sciences Toxicology & Public Health |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-283-23966-3
9786613239662 1-118-00104-4 1-118-00103-6 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Preface; Contributors; 1 Toxicology, ""Omics"" Technologies, and Toxicogenomics: A Primer; 2 Introduction to Human Health Risk Assessment; 3 Practical Considerations for the Application of Toxicogenomics to Risk Assessment: Early Experience, Current Drivers, and a Path Forward; 4 Approaches and Practical Considerations for the Analysis of Toxicogenomics Data; 5 Genomics in Identifying Mutagenic Mode of Action in Carcinogenesis; 6 Application of Genomics for Predicting and Understanding the Mode of Action for Nongenotoxic Carcinogens; 7 Genomics in Characterizing Endocrine Toxicity
8 Studying Organ-Specific Toxicity Using Gene-Expression Profiling9 Toxicogenomic Studies in Human Populations; 10 Toxicogenomics Applied to Ecological Risk Assessment; 11 Analysis of Transcriptomic Dose-Response Data for Toxicology and Risk Assessment; 12 Toxicogenomics as a Tool for Validating Animal to Human Extrapolations in Chemical Risk Assessment: Concepts, Applications, and Challenges; 13 Toxicogenomics and Animal Alternatives; 14 Toxicogenomics and the Regulatory Framework; 15 Standardization of Gene-Expression Information for the Safety Evaluation: Activities in Japan 16 Applying Transcriptional Profiling in Drug Safety Evaluation17 Reframing the Risk Assessment Paradigm: Toward a Systems Biology Approach; Index |
| Record Nr. | UNINA-9910139607903321 |
Boverhof Darrell R
|
||
| Hoboken, : Wiley, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Applications of Toxicogenomics in Safety Evaluation and Risk Assessment [[electronic resource]]
| Applications of Toxicogenomics in Safety Evaluation and Risk Assessment [[electronic resource]] |
| Autore | Boverhof Darrell R |
| Edizione | [First edition.] |
| Pubbl/distr/stampa | Hoboken : , : Wiley, , 2011 |
| Descrizione fisica | 1 online resource (402 pages) |
| Disciplina |
616.042
616/.042 |
| Altri autori (Persone) | GollapudiB. Bhaskar |
| Soggetto topico |
Genetic toxicology
Health risk assessment Risk Assessment Toxicity testing Toxicogenetics Toxicology Pharmacogenetics Risk Risk Management Epidemiologic Measurements Organization and Administration Pharmacology Probability Genetics Public Health Health Occupations Statistics as Topic Biological Science Disciplines Biology Health Services Administration Environment and Public Health Natural Science Disciplines Health Care Health Care Evaluation Mechanisms Epidemiologic Methods Quality of Health Care Investigative Techniques Health Care Quality, Access, and Evaluation Health & Biological Sciences Toxicology & Public Health |
| ISBN |
1-283-23966-3
9786613239662 1-118-00104-4 1-118-00103-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Preface; Contributors; 1 Toxicology, ""Omics"" Technologies, and Toxicogenomics: A Primer; 2 Introduction to Human Health Risk Assessment; 3 Practical Considerations for the Application of Toxicogenomics to Risk Assessment: Early Experience, Current Drivers, and a Path Forward; 4 Approaches and Practical Considerations for the Analysis of Toxicogenomics Data; 5 Genomics in Identifying Mutagenic Mode of Action in Carcinogenesis; 6 Application of Genomics for Predicting and Understanding the Mode of Action for Nongenotoxic Carcinogens; 7 Genomics in Characterizing Endocrine Toxicity
8 Studying Organ-Specific Toxicity Using Gene-Expression Profiling9 Toxicogenomic Studies in Human Populations; 10 Toxicogenomics Applied to Ecological Risk Assessment; 11 Analysis of Transcriptomic Dose-Response Data for Toxicology and Risk Assessment; 12 Toxicogenomics as a Tool for Validating Animal to Human Extrapolations in Chemical Risk Assessment: Concepts, Applications, and Challenges; 13 Toxicogenomics and Animal Alternatives; 14 Toxicogenomics and the Regulatory Framework; 15 Standardization of Gene-Expression Information for the Safety Evaluation: Activities in Japan 16 Applying Transcriptional Profiling in Drug Safety Evaluation17 Reframing the Risk Assessment Paradigm: Toward a Systems Biology Approach; Index |
| Record Nr. | UNINA-9910824275603321 |
|
Boverhof Darrell R
|
||
| Hoboken : , : Wiley, , 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||