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Phage therapy : current research and applications / / edited by Jan Borysowski, Department of Clinical Immunology, The Medical University of Warsaw, Warsaw, Poland, Ryszard Międzybrodzki and Andrzej Górski, Department of Clinical Immunology, The Medical University of Warsaw, Warsaw, and Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland
| Phage therapy : current research and applications / / edited by Jan Borysowski, Department of Clinical Immunology, The Medical University of Warsaw, Warsaw, Poland, Ryszard Międzybrodzki and Andrzej Górski, Department of Clinical Immunology, The Medical University of Warsaw, Warsaw, and Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland |
| Pubbl/distr/stampa | Norfolk, England : , : Caister Academic Press, , [2014] |
| Descrizione fisica | 1 online resource (402 p.) |
| Disciplina | 579.26 |
| Soggetto topico |
Bacteriophages - Therapeutic use
Antibacterial agents |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-908230-74-6 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Contributors; Current books of interest; Foreword; Introduction; Part I: Characteristics of Phages as Antibacterial Agents; 1: General Characteristics of Bacteriophages; Introduction; Discovery; Basic phage techniques (Carlson, 2005); Habitats and ecology; Phage life; Host range; Classification; Genomics; Practical aspects of phage research; Electron microscopy for rapid diagnosis (Ackermann and Heldal, 2009; Ackermann, 2009); Outlook; 2: The First Step to Bacteriophage Therapy: How to Choose the Correct Phage; Introduction: therapeutic phages - what requirements should they meet?
Environmental sources of therapeutic phagesA brief overview of phage isolation methods; The selection of phages that infect encapsulated bacterial cells; Preliminary grouping of phage isolates; Pre-selection of potential therapeutic phages; Perspectives for the prediction of phage therapeutic efficacy; Purification of phage lysates; Bacteriophage stability; Host range determination; Bacterial strains for therapeutic phage propagation; Bacterial phage resistance - is it a concern?; Concluding remarks; 3: Bacteriophages as Drugs: The Pharmacology of Phage Therapy; Introduction; Pharmacology Primary pharmacodynamicsSecondary pharmacodynamics; Accumulation rates; Concentrations; Absorption and distribution; Spectrum of activity; Development issues; Conclusion; 4: Fighting Bacteriophage Infection: Mechanisms of Bacterial Resistance; Introduction; Preventing phage adsorption; Preventing phage DNA entry; Degradation of phage nucleic acids; Abortive infection systems; Conclusion; 5: Non-bactericidal Effects of Phages in Mammals; Introduction; Phages and cell adhesion; Overview of main aspects of phage antigenicity; The influence of phages on cytokine production Phage influence on phagocytosis and oxidative burstEngineered phages as vaccines; Phages and pathogenic viruses of mammals; Remarks on bacterial remains in phage preparations; Conclusions; Part II: Applications of Phages and Phage-derived Enzymes as Antibacterials; 6: Overview of Therapeutic Applications of Bacteriophages; The use of lytic phages; The therapeutic use of phage lysins; Genetically engineered phages; Phages as delivery vectors; 7: Considerations for Using Bacteriophages in Plant Pathosystems; Introduction; Impediments in using phage therapy in plant pathology Future considerations for improving phage efficacyPhages as part of integrated management strategy; Conclusions; 8: Bacteriophage Therapy in Animal Production; Introduction; Bacteriophage therapy in poultry production; Bacteriophage therapy in swine production; Bacteriophage therapy in beef, dairy and cattle production; Bacteriophage therapy in aquaculture; General discussion; 9: The Use of Phages as Biocontrol Agents in Foods; Introduction; Bacteriophages as biocontrol agents; The use of phages as biocontrol agents against specific food-borne bacteria Main factors that determine the efficacy of phages as biocontrol agents |
| Record Nr. | UNINA-9910463987903321 |
| Norfolk, England : , : Caister Academic Press, , [2014] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Phage therapy : current research and applications / / edited by Jan Borysowski, Department of Clinical Immunology, The Medical University of Warsaw, Warsaw, Poland, Ryszard Międzybrodzki and Andrzej Górski, Department of Clinical Immunology, The Medical University of Warsaw, Warsaw, and Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland
| Phage therapy : current research and applications / / edited by Jan Borysowski, Department of Clinical Immunology, The Medical University of Warsaw, Warsaw, Poland, Ryszard Międzybrodzki and Andrzej Górski, Department of Clinical Immunology, The Medical University of Warsaw, Warsaw, and Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland |
| Pubbl/distr/stampa | Norfolk, England : , : Caister Academic Press, , [2014] |
| Descrizione fisica | 1 online resource (402 p.) |
| Disciplina | 579.26 |
| Soggetto topico |
Bacteriophages - Therapeutic use
Antibacterial agents |
| ISBN | 1-908230-74-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Contributors; Current books of interest; Foreword; Introduction; Part I: Characteristics of Phages as Antibacterial Agents; 1: General Characteristics of Bacteriophages; Introduction; Discovery; Basic phage techniques (Carlson, 2005); Habitats and ecology; Phage life; Host range; Classification; Genomics; Practical aspects of phage research; Electron microscopy for rapid diagnosis (Ackermann and Heldal, 2009; Ackermann, 2009); Outlook; 2: The First Step to Bacteriophage Therapy: How to Choose the Correct Phage; Introduction: therapeutic phages - what requirements should they meet?
Environmental sources of therapeutic phagesA brief overview of phage isolation methods; The selection of phages that infect encapsulated bacterial cells; Preliminary grouping of phage isolates; Pre-selection of potential therapeutic phages; Perspectives for the prediction of phage therapeutic efficacy; Purification of phage lysates; Bacteriophage stability; Host range determination; Bacterial strains for therapeutic phage propagation; Bacterial phage resistance - is it a concern?; Concluding remarks; 3: Bacteriophages as Drugs: The Pharmacology of Phage Therapy; Introduction; Pharmacology Primary pharmacodynamicsSecondary pharmacodynamics; Accumulation rates; Concentrations; Absorption and distribution; Spectrum of activity; Development issues; Conclusion; 4: Fighting Bacteriophage Infection: Mechanisms of Bacterial Resistance; Introduction; Preventing phage adsorption; Preventing phage DNA entry; Degradation of phage nucleic acids; Abortive infection systems; Conclusion; 5: Non-bactericidal Effects of Phages in Mammals; Introduction; Phages and cell adhesion; Overview of main aspects of phage antigenicity; The influence of phages on cytokine production Phage influence on phagocytosis and oxidative burstEngineered phages as vaccines; Phages and pathogenic viruses of mammals; Remarks on bacterial remains in phage preparations; Conclusions; Part II: Applications of Phages and Phage-derived Enzymes as Antibacterials; 6: Overview of Therapeutic Applications of Bacteriophages; The use of lytic phages; The therapeutic use of phage lysins; Genetically engineered phages; Phages as delivery vectors; 7: Considerations for Using Bacteriophages in Plant Pathosystems; Introduction; Impediments in using phage therapy in plant pathology Future considerations for improving phage efficacyPhages as part of integrated management strategy; Conclusions; 8: Bacteriophage Therapy in Animal Production; Introduction; Bacteriophage therapy in poultry production; Bacteriophage therapy in swine production; Bacteriophage therapy in beef, dairy and cattle production; Bacteriophage therapy in aquaculture; General discussion; 9: The Use of Phages as Biocontrol Agents in Foods; Introduction; Bacteriophages as biocontrol agents; The use of phages as biocontrol agents against specific food-borne bacteria Main factors that determine the efficacy of phages as biocontrol agents |
| Record Nr. | UNINA-9910787832603321 |
| Norfolk, England : , : Caister Academic Press, , [2014] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Phage therapy : current research and applications / / edited by Jan Borysowski, Department of Clinical Immunology, The Medical University of Warsaw, Warsaw, Poland, Ryszard Międzybrodzki and Andrzej Górski, Department of Clinical Immunology, The Medical University of Warsaw, Warsaw, and Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland
| Phage therapy : current research and applications / / edited by Jan Borysowski, Department of Clinical Immunology, The Medical University of Warsaw, Warsaw, Poland, Ryszard Międzybrodzki and Andrzej Górski, Department of Clinical Immunology, The Medical University of Warsaw, Warsaw, and Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland |
| Pubbl/distr/stampa | Norfolk, England : , : Caister Academic Press, , [2014] |
| Descrizione fisica | 1 online resource (402 p.) |
| Disciplina | 579.26 |
| Soggetto topico |
Bacteriophages - Therapeutic use
Antibacterial agents |
| ISBN | 1-908230-74-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Contributors; Current books of interest; Foreword; Introduction; Part I: Characteristics of Phages as Antibacterial Agents; 1: General Characteristics of Bacteriophages; Introduction; Discovery; Basic phage techniques (Carlson, 2005); Habitats and ecology; Phage life; Host range; Classification; Genomics; Practical aspects of phage research; Electron microscopy for rapid diagnosis (Ackermann and Heldal, 2009; Ackermann, 2009); Outlook; 2: The First Step to Bacteriophage Therapy: How to Choose the Correct Phage; Introduction: therapeutic phages - what requirements should they meet?
Environmental sources of therapeutic phagesA brief overview of phage isolation methods; The selection of phages that infect encapsulated bacterial cells; Preliminary grouping of phage isolates; Pre-selection of potential therapeutic phages; Perspectives for the prediction of phage therapeutic efficacy; Purification of phage lysates; Bacteriophage stability; Host range determination; Bacterial strains for therapeutic phage propagation; Bacterial phage resistance - is it a concern?; Concluding remarks; 3: Bacteriophages as Drugs: The Pharmacology of Phage Therapy; Introduction; Pharmacology Primary pharmacodynamicsSecondary pharmacodynamics; Accumulation rates; Concentrations; Absorption and distribution; Spectrum of activity; Development issues; Conclusion; 4: Fighting Bacteriophage Infection: Mechanisms of Bacterial Resistance; Introduction; Preventing phage adsorption; Preventing phage DNA entry; Degradation of phage nucleic acids; Abortive infection systems; Conclusion; 5: Non-bactericidal Effects of Phages in Mammals; Introduction; Phages and cell adhesion; Overview of main aspects of phage antigenicity; The influence of phages on cytokine production Phage influence on phagocytosis and oxidative burstEngineered phages as vaccines; Phages and pathogenic viruses of mammals; Remarks on bacterial remains in phage preparations; Conclusions; Part II: Applications of Phages and Phage-derived Enzymes as Antibacterials; 6: Overview of Therapeutic Applications of Bacteriophages; The use of lytic phages; The therapeutic use of phage lysins; Genetically engineered phages; Phages as delivery vectors; 7: Considerations for Using Bacteriophages in Plant Pathosystems; Introduction; Impediments in using phage therapy in plant pathology Future considerations for improving phage efficacyPhages as part of integrated management strategy; Conclusions; 8: Bacteriophage Therapy in Animal Production; Introduction; Bacteriophage therapy in poultry production; Bacteriophage therapy in swine production; Bacteriophage therapy in beef, dairy and cattle production; Bacteriophage therapy in aquaculture; General discussion; 9: The Use of Phages as Biocontrol Agents in Foods; Introduction; Bacteriophages as biocontrol agents; The use of phages as biocontrol agents against specific food-borne bacteria Main factors that determine the efficacy of phages as biocontrol agents |
| Record Nr. | UNINA-9910813756103321 |
| Norfolk, England : , : Caister Academic Press, , [2014] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Phage Therapy: A Practical Approach / / edited by Andrzej Górski, Ryszard Międzybrodzki, Jan Borysowski
| Phage Therapy: A Practical Approach / / edited by Andrzej Górski, Ryszard Międzybrodzki, Jan Borysowski |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (384 pages) |
| Disciplina | 579.26 |
| Soggetto topico |
Medical microbiology
Molecular biology Medical Microbiology Molecular Medicine Bacteriòfags Microbiologia mèdica |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-26736-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I: Bacteriophages as antibacterialagents -- Chapter 1:Production of PhageTherapeutics and Formulations – InnovativeApproaches -- Chapter 2:Phagepharmacokinetics: relationship with administrationroute -- Chapter 3:BacterialResistance to Phage and itsImpact on Clinical Therapy -- Part II: Bacteriophages and the immune system -- Chapter 4:Phageinteraction with the mammalianimmune system -- Chapter 5:Humoralimmuneresponse to phage-basedtherapeutics -- Part III:Use of bacteriophages to combat bacterial infections -- Chapter 6:How to achieve a goodphage therapy clinical trial? -- Chapter 7: Perspectives on the RenewedInterest in the United States -- Chapter 8:Phage Therapy in Orthopaedic Implant-associated Infections -- Chapter 9:The use of bacteriophages in animalhealth and food protection -- Chapter 10:Combiningbacteriophages with otherantibacterialagents to combatbacteria -- Chapter 11: Phage therapy of infectious biofilms: Challenges and strategies -- Part IV:Phage therapy – regulatory and ethical aspects -- Chapter 12:Regulatory Considerations for Bacteriophage Therapy Products -- Chapter 13:Developing phagesintomedicines for Europe -- Chapter 14: Phagetherapy in Europe: Regulatory and intellectualpropertyprotectionissues -- Chapter 15:Ethics of phagetherapy -- Part V: Bacteriophage-derived antibacterial agents -- Chapter 16: NovelAlternative to Antibiotics. |
| Record Nr. | UNINA-9910349438503321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||