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Biology of pericytes-recent advances / / Alexander Birbrair, editor
| Biology of pericytes-recent advances / / Alexander Birbrair, editor |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (283 pages) |
| Disciplina | 574.87 |
| Collana | Stem Cell Biology and Regenerative Medicine |
| Soggetto topico |
Cytology
Cells Citologia Perícit |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-62129-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910484872003321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pericyte Biology - Novel Concepts / / edited by Alexander Birbrair
| Pericyte Biology - Novel Concepts / / edited by Alexander Birbrair |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (171 pages) |
| Disciplina | 574.87 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Stem cells
Regenerative medicine Tissue engineering Cancer research Cardiovascular system Stem Cells Regenerative Medicine/Tissue Engineering Cancer Research Cardiovascular Biology |
| ISBN | 3-030-02601-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Editorial preview – Pericyte Biology: Development, Homeostasis and Disease -- The NG2 Proteoglycan in Pericyte Biology -- Pericytes for Therapeutic Bone Repair -- Pericytes Biology in Zebrafish -- The Microvascular Pericyte: Approaches to Isolation, Characterization and Cultivation -- Pericytes in veterinary species - prospective isolation, characterization and tissue regeneration potential -- Pericytes in the Human Vocal Fold Mucosa -- Ca2+ signalling in pericytes -- Pericytes derived from Human Pluripotent Stem Cells -- Pericytes in Tissue Engineering -- Pericyte secretome -- Index. |
| Record Nr. | UNINA-9910303442403321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pericyte Biology in Different Organs / / edited by Alexander Birbrair
| Pericyte Biology in Different Organs / / edited by Alexander Birbrair |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (283 pages) |
| Disciplina | 611.0187 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Stem cells
Regenerative medicine Tissue engineering Cancer research Stem Cells Regenerative Medicine/Tissue Engineering Cancer Research |
| ISBN | 3-030-11093-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Pericytes in the retina -- Pancreatic pericytes in glucose homeostasis and diabetes -- Pericytes in the lung -- Pericytes in the skeletal muscle -- Pericytes in the gut -- Pericytes in the bone marrow -- Cochlear Capillary Pericytes -- Pericytes in the placenta: role in placental development and homeostasis -- Pericytes in the liver -- Pericytes in the Periodontal Ligament -- Pericytes in the heart -- Pericytes in the Umbilical Cord -- The pluripotent microvascular pericytes are the adult stem cells even in the testis -- Index . . |
| Record Nr. | UNINA-9910337955803321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pericyte Biology in Disease / / edited by Alexander Birbrair
| Pericyte Biology in Disease / / edited by Alexander Birbrair |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (359 pages) |
| Disciplina |
612.13
571.6 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Stem cells
Regenerative medicine Tissue engineering Cancer research Stem Cells Regenerative Medicine/Tissue Engineering Cancer Research |
| ISBN | 3-030-16908-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Pericytes in cutaneous wound healing -- Pericytes in glioblastomas: multifaceted role within tumor microenvironments and potential for therapeutic interventions -- Pericytes in breast cancer -- Pericytes in sarcomas and other mesenchymal tumors -- Pericytes in metastasis -- The role of pericytes in Amyotrophic Lateral Sclerosis -- Pericytes in Alzheimer’s Disease: novel clues to cerebral amyloid angiopathy pathogenesis -- Pericytes in Multiple Sclerosis -- Pericytes in ischemic stroke -- Pericytes in Hereditary Hemorrhagic Telangiectasia -- Pericytes in primary familial brain calcification -- Pericytes in type 2 diabetes -- Pericytes in atherosclerosis -- Pericytes in chronic lung disease -- Pericytes in muscular dystrophies -- Index . |
| Record Nr. | UNINA-9910337944803321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Stem Cell Microenvironments and Beyond / / edited by Alexander Birbrair
| Stem Cell Microenvironments and Beyond / / edited by Alexander Birbrair |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (XI, 270 p. 445 illus., 432 illus. in color.) |
| Disciplina | 616.02774 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Stem cells
Regenerative medicine Tissue engineering Cancer research Stem Cells Regenerative Medicine/Tissue Engineering Cancer Research |
| ISBN | 3-319-69194-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Stem Cell Microenvironments and Beyond -- 2. The bone marrow microenvironment for hematopoietic stem cells -- 3. Leukemia stem cells microenvironment -- 4. Developmental HSC Microenvironments: Lessons from Zebrafish -- 5. Spinal cord stem cells microenvironment: the ependyme as a stem cell niche -- 6. Being a Neural Stem Cell: a matter of character but defined by the microenvironment -- 7. Glioblastoma Stem Cells and their Microenvironment -- 8. Plasticity of the Muscle Stem Cell Microenvironment -- 9. The Macula Flava of the Human Vocal Fold as a Stem Cell Microenvironment -- 10. Oesophageal stem cells microenvironment -- 11. Oral cancer stem cells microenvironment -- 12 Fetal membranes-derived stem cells microenvironment -- 13. Current technologies based on the knowledge of the stem cells microenvironments. . |
| Record Nr. | UNINA-9910253947103321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Stem Cells Heterogeneity - Novel Concepts / / edited by Alexander Birbrair
| Stem Cells Heterogeneity - Novel Concepts / / edited by Alexander Birbrair |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (225 pages) |
| Disciplina | 616.02774 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Stem cells
Regenerative medicine Tissue engineering Cancer research Cell cycle Stem Cells Regenerative Medicine/Tissue Engineering Cancer Research Cell Cycle Analysis |
| ISBN | 3-030-11096-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Stem cells heterogeneity -- Heterogeneity in epiblast stem cells -- Progenitor cell heterogeneity in the adult carotid body germinal niche -- Planarian stem cell heterogeneity -- The cellular origin of Barrett’s esophagus and its stem cells -- Pluripotent stem cell heterogeneity -- Sarcoma stem cell heterogeneity -- Heterogeinity in adipose derived stem cells -- Unveiling stem cell heterogeneity towards the development of salivary gland regenerative strategies -- Heterogeneity of human mesenchymal stromal/stem cells -- Mitochondrial heterogeneity in stem cells -- The heterogeneity of renal stem cells, and their interaction with bio- and nano-materials -- Index. |
| Record Nr. | UNINA-9910337955703321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Stem Cells Heterogeneity in Cancer / / edited by Alexander Birbrair
| Stem Cells Heterogeneity in Cancer / / edited by Alexander Birbrair |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (232 pages) |
| Disciplina |
616.99407
616.02774 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Stem cells
Regenerative medicine Tissue engineering Cancer research Cell cycle Stem Cells Regenerative Medicine/Tissue Engineering Cancer Research Cell Cycle Analysis |
| ISBN | 3-030-14366-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Multilayered heterogeneity of glioblastoma stem cells: biological and clinical significance -- Heterogeneity of head and neck squamous cell carcinoma stem cells -- Heterogeneity of small cell lung cancer stem cells -- Heterogeneity of hepatic cancer stem cells -- Heterogeneity and plasticity of breast cancer stem cells -- Heterogeneity of melanoma with stem cell properties -- Heterogeneity of colon cancer stem cells -- Urothelial cancer stem cell heterogeneity -- Acute myeloid leukemia stem cell heterogeneity and its clinical relevance -- Contribution of chronic myeloid leukaemia (CML) as a disease model to define and study clonal heterogeneity -- The heterogeneity of osteosarcoma: the role played by cancer stem cells -- Ovarian cancer stem cell heterogeneity -- Index. |
| Record Nr. | UNINA-9910337947503321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Stem Cells Heterogeneity in Different Organs / / edited by Alexander Birbrair
| Stem Cells Heterogeneity in Different Organs / / edited by Alexander Birbrair |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (XII, 266 p. 48 illus., 46 illus. in color.) |
| Disciplina |
571.6
616.02774 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Stem cells
Regenerative medicine Tissue engineering Cell cycle Stem Cells Regenerative Medicine/Tissue Engineering Cell Cycle Analysis |
| ISBN | 3-030-24108-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Heterogeneity of Neural Stem Cells in the Ventricular-Subventricular Zone -- Heterogeneity of Stem Cells in the Hippocampus -- Heterogeneity of Sweat Gland Stem Cells -- Heterogeneity of Stem Cells in the Human Vocal Fold Mucosa -- Heterogeneity of Stem Cells in the Thyroid -- Heterogeneity of Pulmonary Stem Cells -- Heterogeneity of Mammary Stem Cells -- Heterogeneity of Adult Cardiac Stem Cells -- Skeletal Muscle Progenitor Cell Heterogeneity -- Hematopoietic Stem Cell Heterogeneity -- Heterogeneity of Stem Cells in the Ovary -- Heterogeneity of spermatogonial stem cells -- Sources, Identification and Clinical Implications of Heterogeneity in Human Umbilical Cord Stem Cells -- Index. |
| Record Nr. | UNINA-9910349445103321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Tumor microenvironment Signaling pathways . Part B / / Alexander Birbrair, editor
| Tumor microenvironment Signaling pathways . Part B / / Alexander Birbrair, editor |
| Edizione | [1st ed. 2021.] |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (XIII, 191 p. 31 illus., 25 illus. in color.) |
| Disciplina | 616.994 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Tumors - Molecular aspects
Cancer - Molecular aspects |
| ISBN | 3-030-47189-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Neuregulin signaling in the tumor microenvironment -- HGF/c-Met signalling in the tumor microenvironment -- Eph/ephrin signaling in the tumor microenvironment -- Src signaling in cancer and tumor microenvironment -- Purinergic signaling within the tumor microenvironment -- TGFβ signalling in the tumor microenvironment -- Wnt Signaling in the Tumor Microenvironment -- Lysophospholipid Signalling and the Tumour Microenvironment -- Adenosine signaling in the tumor microenvironment -- Androgen signaling in the tumor microenvironment -- Index. |
| Record Nr. | UNINA-9910485147603321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumor microenvironment : novel concepts / / Alexander Birbrair, editor
| Tumor microenvironment : novel concepts / / Alexander Birbrair, editor |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (546 pages) |
| Disciplina | 616.994 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Cancer - Molecular aspects
Tumors - Molecular aspects Tumors |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-73119-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Contents -- About the Editor -- The Tumour Microenvironment and Circulating Tumour Cells: A Partnership Driving Metastasis and Glycan-Based Opportunities for Cancer Control -- 1 Introduction -- 2 Tumour Microenvironment Promotion of EMT and Tumour Invasion -- 3 Tumour Microenvironment Promotion of Haematogenous Metastasis -- 4 Tumour Microenvironment Promotion of CTC Colonization -- 4.1 Tumour-Secreted Soluble Factors -- 4.2 Tumour-Derived Exosomes -- 5 Adaptation of CTC to Foreign Site Microenvironments -- 6 Glycosylation: A Key Post-translational Modification Driving Metastasis and Its Potential for Targeted Therapeutics -- 7 Concluding Remarks -- 8 Ongoing Challenges and Future Perspectives -- References -- Dormancy in the Tumor Microenvironment -- 1 Introduction -- 2 Osteogenic and Stem Cell-Driven Dormancy -- 3 Vascular/Angiogenic Dormancy -- 4 Hypoxia -- 5 Immunologic Dormancy -- 6 Conclusion -- References -- Tumor-Associated Tertiary Lymphoid Structures: A Cancer Biomarker and a Target for Next-generation Immunotherapy -- 1 Introduction -- 2 TLS Versus SLO: Which Came First in Animal Evolution? -- 3 TLS and SLO: Is There Redundancy in the Immune System? -- 4 TLS: a Powerful Prognostic Biomarker in Cancers -- 4.1 Prognostic Factor Across Human Cancer Types -- 4.2 Methods for TLS Quantification -- 5 TLS: A Key Target for Next-generation Immunotherapy -- 6 Conclusion and Perspectives -- References -- Studying the Tumor Microenvironment in Zebrafish -- 1 Introduction -- 2 Innate Immune Cells in the Zebrafish TME -- 2.1 Recruitment and Pro-tumor Functions -- 2.1.1 Neutrophils and Macrophages -- 2.1.2 Microglia/Macrophages -- 2.2 The Role of Innate Immune Cells in Metastasis -- 2.2.1 Neutrophils -- 2.2.2 Macrophages -- 2.2.3 Endothelial Cells, Extravasation, and Proliferation at the Metastatic Site.
3 A Role of Adipocytes in Tumor Growth and Invasion -- 4 Fibroblasts -- 5 Neo-angiogenesis -- 6 Future Directions -- References -- Pre-metastatic Niche Formation by Neutrophils in Different Organs -- 1 Introduction -- 2 Neutrophil Development -- 3 Emergency Granulopoiesis -- 4 Neutrophils in Cancer -- 5 Metastasis and Metastatic Seeding -- 6 Pre-metastatic Niche -- 7 Recruitment of Neutrophils into Pre-metastatic Organs -- 8 The Influence of Neutrophils on the Formation of Pre-metastatic Niche -- 8.1 Inflammation as a Stimulus for Metastasis -- 8.2 Deregulation of Adaptive Immune Responses -- 8.3 Direct Support of Tumor Cell Growth by Neutrophils -- 8.4 Released Neutrophil Factors Support Tumor Survival -- 8.5 NETosis as Pro-metastatic Factor -- 9 Summary and Future Perspectives -- References -- Tumor Cell Invasion and the Tumor Microenvironment: Special Focus on Brain Tumors -- 1 Introduction -- 2 General Features of the Invasive Process in Glioblastoma -- 3 Invasive Mechanisms at the Level of Tumor Cells -- 4 Brain Tumor Blood Vessels, Vessel Co-option, and Invasion -- 5 Immune System and Tumor Cell Invasion -- 6 Invasion of White Matter Tracts by Glioma Cells -- 7 Role of Tumor-Associated Astrocytes in Glioblastoma Invasion -- 8 Role of the Extracellular Matrix in Tumor Invasion -- 9 Conclusion -- References -- The Dog as a Model to Study the Tumor Microenvironment -- 1 Introduction -- 2 Components of Tumor Microenvironment -- 3 A Special Insight on the Role of Macrophages and T-Lymphocytes in Tumor Microenvironment -- 3.1 Macrophage, The Head of the Orchestra -- 3.1.1 Macrophages and Tumor Initiation: A Crosstalk with a Chronic Inflammation State -- 3.1.2 Macrophages and Tumor Metastasization -- 3.1.3 Macrophages as Therapeutic Targets in Cancer -- 3.2 T-Lymphocytes in the Tumor Microenvironment -- 3.2.1 T-Lymphocytes and Tumor Initiation. 3.2.2 T-Lymphocytes and Tumor Metastization -- 3.2.3 Lymphocytes as Therapeutic Targets in Cancer -- 3.3 Lactate Efflux and the Interaction with T-Lymphocytes and Macrophages in Tumor Microenvironment: A Dance with the "Wolfs" -- 3.3.1 Cancer Progression and Immunologic Escape -- 3.3.2 Lactic Acid and Tumor Metastasization -- 4 Concluding Remarks -- References -- Efferocytosis and the Story of "Find Me," "Eat Me," and "Don't Eat Me" Signaling in the Tumor Microenvironment -- 1 Introduction -- 2 Cellular Mechanism of Efferocytosis -- 3 Tumor Survival and Metastasis Need Efferocytosis -- 4 Conclusion and Future Perspectives -- References -- Color-Coded Imaging of the Tumor Microenvironment (TME) in Human Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models -- 1 Introduction -- 2 Materials and Methods -- 2.1 Mice -- 2.2 Animal Care -- 2.3 Establishment of a PDOX Model of Patient Tumors -- 2.4 Patient-Derived Orthotopic Xenograft (PDOX) Transgenic Fluorescent Protein-Expressing Nude Mouse Models -- 2.5 Establishment of a PDOX Model of Soft Tissue Sarcoma -- 2.6 Fluorescence Imaging -- 2.7 Confocal Microscopy -- 2.8 Histological Analysis -- 2.9 GFP-Expressing Telomerase-Specific Adenovirus -- 2.10 OBP-401-GFP Labeling of an RFP-Expressing PDOX -- 3 Results and Discussion -- 3.1 GFP Host Stromal Cells Infiltrate a Pancreatic Cancer PDOX -- 3.2 GFP Host Stromal Cells Infiltrate Peritoneal-Disseminated Metastases of Pancreatic Cancer PDOX -- 3.3 RFP Host Stromal Cells Infiltrate Pancreatic Cancer PDOX -- 3.4 GFP Host Stromal Cells Infiltrate Pancreatic PDOX Labeled with RFP Stroma to Form a Two-Color Stroma Model -- 3.5 CFP Host Stromal Cells Infiltrate Pancreatic Cancer PDOX Previously Grown in RFP and GFP Transgenic Mice to Form a Three-Color Stroma Model -- 3.6 OBP-401-GFP Labeling of Cancer Cells in Pancreatic Cancer PDOX with RFP-Expressing Stroma. 3.7 Color-Coded Imaging to Visualize Selective Stromal Cell Therapy -- 3.8 Noninvasive Imaging of a PDOX Sarcoma in Noncolored Nude Mouse After a Single Passage in RFP Nude Mouse -- 3.9 Imaging of Body Imaging and the RFP Stroma in the UPS Imageable PDOX (iPDOX) Model During Multiple Passages -- 4 Conclusion -- References -- Mitochondria and the Tumour Microenvironment in Blood Cancer -- 1 Introduction -- 2 The Bone Marrow -- 3 Haematopoiesis -- 4 Bone Marrow Microenvironment -- 4.1 HSC Niche -- 4.2 Cell Compartments of the BM Microenvironment -- 4.3 BMSC and Normal Haematopoiesis -- 5 Aging and Tumour Microenvironment of the BM -- 5.1 Aging -- 5.2 Blood Cancer -- 5.3 Multiple Myeloma -- 5.4 Acute Lymphoblastic Leukaemia -- 5.5 Acute Myeloid Leukaemia -- 6 Mitochondria and Mitochondrial Transfer to Malignant Blood Cells -- 6.1 Mitochondria -- 6.2 Mitochondrial Transfer -- 6.3 Tunnelling Nanotubules -- 6.4 Extracellular Vesicles -- 6.5 Gap Junctions -- 7 Mitochondrial Transfer and Microenvironment in Solid Tumours -- 8 Conclusions -- References -- Telocytes in the Tumor Microenvironment -- 1 Introduction -- 2 The Nature of Telocytes -- 3 Tumor Angiogenesis -- 4 Telocytes and Signaling Molecules -- 5 Telocytes and Immune Cells -- 6 Telocytes and Fibroblasts -- 7 The Role of Telocytes in the Production of Extracellular Matrix -- 8 Conclusions and Future Directions -- References -- Modeling the Roles of Astrocytes in the Metastatic Tumor Cell Microenvironment -- 1 Introduction -- 2 Two-Dimensional (2D) Models -- 2.1 2D Single-Cell Assays -- 2.2 2D Scratch Assay -- 2.3 Two-Dimensional Coculture Assay -- 3 Three-Dimensional (3D) Models -- 3.1 Transwell Insert Models (Boyden Chambers) -- 3.2 Spheroid Culture -- 4 Effect of Astrocytes on Endothelial Cells -- 5 In Vivo Models -- 6 Human Samples -- 7 Microfluidic Models -- 8 Conclusion and Outlook. References -- Roles of Fibroblasts in Microenvironment Formation Associated with Radiation-Induced Cancer -- 1 Introduction -- 2 Fibroblasts in Tumor Microenvironment -- 3 Effects of Radiation on Human Health -- 4 Radiation-Induced Cancer -- 5 Mitochondria as a Biological Radiation Target -- 6 Roles of ATM in Mitochondrial Radiation Response -- 7 Oxidative Stress and Cancer -- 8 Tumor Microenvironment in Radiation-Related Cancer -- References -- Tumor Microenvironment-Associated Pericyte Populations May Impact Therapeutic Response in Thyroid Cancer -- 1 Introduction -- 2 Ontogeny and Lineage of Pericytes -- 3 Biology of Pericytes -- 4 Pericyte and Normal Thyroid Function -- 5 Thyroid Cancer Microenvironment -- 6 Role of Pericytes in Tumor Metastasis -- 7 Role of Pericyte in Drug Resistance -- 8 Targeting Pathways That Are Functional in Pericytes -- 9 Conclusions -- References -- The Adrenergic Nerve Network in Cancer -- 1 Introduction -- 2 Main Text -- 2.1 Adrenergic Nerve Signaling Bridges the Brain and Peripheral Tumors -- 2.2 Adrenergic Axonogenesis and Neurogenesis in the Tumor Microenvironment -- 2.3 Adrenergic Signaling and Crosstalk in Tumors -- 2.3.1 Adrenergic Signaling and Crosstalk with Cancer Cells -- 2.3.2 Adrenergic Signaling and Crosstalk with the TME -- Immune Cells -- Endothelial Cells -- Lymphatic Cells -- Mesenchymal Stem Cells, Cancer-Associated Fibroblasts, and Adipocytes -- 2.4 Adrenergic Signaling and Therapies -- 3 Commentary -- References -- Current Treatment Modalities Targeting Tumor Microenvironment in Castration-Resistant Prostate Cancer -- 1 Introduction -- 1.1 Tumor Microenvironment in Prostate Cancer Progression -- 1.2 Secondary Hormonal Manipulations -- 1.3 Chemotherapy in Metastatic CRPC -- 1.4 Taxanes -- 1.5 Targeting Immune Checkpoint Inhibitors -- 1.6 Targeting Inhibitors of Steroidogenic Enzymes. 1.7 Tyrosine Kinase Inhibitors |
| Record Nr. | UNINA-9910506392803321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
