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Atherothrombosis in clinical practice [[electronic resource] /] / edited by Deepak L. Bhatt
Atherothrombosis in clinical practice [[electronic resource] /] / edited by Deepak L. Bhatt
Pubbl/distr/stampa Oxford ; ; New York, : Oxford University Press, c2013
Descrizione fisica 1 online resource (177 p.)
Disciplina 616.1/36
Altri autori (Persone) BhattDeepak L
Collana Oxford American cardiology library
Soggetto topico Atherosclerosis
Coronary heart disease
Soggetto genere / forma Electronic books.
ISBN 0-19-997676-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Contents; Preface; Contributors; 1. Atherothrombosis; 2. Coronary Artery Disease; 3. Valvular Heart Disease; 4. Cerebrovascular Disease: Ischemic Syndromes Due to Atherothrombosis; 5. Atrial Fibrillation; 6. Peripheral Artery Disease; 7. Lipid-Modifying Therapy; 8. Antithrombotic Therapy; 9. Treatment of Primary Hypertension; 10. Therapy for Type 2 Diabetes; Index; A; B; C; D; E; F; G; H; I; L; M; N; O; P; R; S; T; U; V; W
Record Nr. UNINA-9910452960003321
Oxford ; ; New York, : Oxford University Press, c2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Atherothrombosis in clinical practice [[electronic resource] /] / edited by Deepak L. Bhatt
Atherothrombosis in clinical practice [[electronic resource] /] / edited by Deepak L. Bhatt
Pubbl/distr/stampa Oxford ; ; New York, : Oxford University Press, c2013
Descrizione fisica 1 online resource (177 p.)
Disciplina 616.1/36
Altri autori (Persone) BhattDeepak L
Collana Oxford American cardiology library
Soggetto topico Atherosclerosis
Coronary heart disease
ISBN 0-19-997676-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Contents; Preface; Contributors; 1. Atherothrombosis; 2. Coronary Artery Disease; 3. Valvular Heart Disease; 4. Cerebrovascular Disease: Ischemic Syndromes Due to Atherothrombosis; 5. Atrial Fibrillation; 6. Peripheral Artery Disease; 7. Lipid-Modifying Therapy; 8. Antithrombotic Therapy; 9. Treatment of Primary Hypertension; 10. Therapy for Type 2 Diabetes; Index; A; B; C; D; E; F; G; H; I; L; M; N; O; P; R; S; T; U; V; W
Record Nr. UNINA-9910779856603321
Oxford ; ; New York, : Oxford University Press, c2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Atherothrombosis in clinical practice / / edited by Deepak L. Bhatt
Atherothrombosis in clinical practice / / edited by Deepak L. Bhatt
Edizione [1st ed.]
Pubbl/distr/stampa Oxford ; ; New York, : Oxford University Press, c2013
Descrizione fisica 1 online resource (177 p.)
Disciplina 616.1/36
Altri autori (Persone) BhattDeepak L
Collana Oxford American cardiology library
Soggetto topico Atherosclerosis
Coronary heart disease
ISBN 0-19-997676-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Contents; Preface; Contributors; 1. Atherothrombosis; 2. Coronary Artery Disease; 3. Valvular Heart Disease; 4. Cerebrovascular Disease: Ischemic Syndromes Due to Atherothrombosis; 5. Atrial Fibrillation; 6. Peripheral Artery Disease; 7. Lipid-Modifying Therapy; 8. Antithrombotic Therapy; 9. Treatment of Primary Hypertension; 10. Therapy for Type 2 Diabetes; Index; A; B; C; D; E; F; G; H; I; L; M; N; O; P; R; S; T; U; V; W
Record Nr. UNINA-9910821095103321
Oxford ; ; New York, : Oxford University Press, c2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Cardiovascular clinical trials [[electronic resource] ] : putting the evidence into practice / / edited by Marcus Flather, Deepak L. Bhatt, Tobias Geisler
Cardiovascular clinical trials [[electronic resource] ] : putting the evidence into practice / / edited by Marcus Flather, Deepak L. Bhatt, Tobias Geisler
Pubbl/distr/stampa Chichester, West Sussex, : Wiley-Blackwell, 2012
Descrizione fisica 1 online resource (413 p.)
Disciplina 616.100724
Altri autori (Persone) FlatherM
BhattDeepak L
GeislerTobias
Soggetto topico Cardiovascular system - Diseases - Treatment
Cardiology, Experimental
ISBN 1-283-60427-2
1-118-39937-4
9786613916723
1-118-39935-8
1-118-39934-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Title page; Copyright page; Contents; List of Contributors; Preface; List of Abbreviations; CHAPTER 1: Introduction to randomized clinical trials in cardiovascular disease; What is a randomized clinical trial?; Concept of randomization; Clinical trial phases; Preclinical studies; Phase 1 clinical trials; Phase 2 clinical trials; Phase 3 clinical trials; Phase 4 clinical trials; Study objective; Study populations; Efficacy variables; Surrogate variables; Control groups; Placebo-controlled trials; Active-control trials; Study design (bias); Methods of randomization; Minimization
Random and systematic errorStudy design issues to overcome systematic bias; Blinding; Study design (samples); Comparisons; Trials to show superiority; Trials to show equivalence or non-inferiority; Trials to show a dose-response relationship; Study protocol; Trial monitoring; Data monitoring; Data analysis sets; Intention-to-treat analysis and data set; Per protocol analysis and on-treatment analysis data sets; Subgroup analysis data sets; Unit of analysis; Missing data; Sensitivity analysis; Analysis methods; Demographic and other baseline characteristics
Measurements of treatment complianceAnalysis of efficacy; Distribution of data; Statistical analysis of clinical trials (elementary concepts); Adjustments for covariates; Time to event ("survival") analysis; Sample size and power; Safety evaluation; Subsets and more; Types of significance; Statistical significance; Practical or "clinical" significance; How have trials contributed to medical care?; Clinical trials for treatment of high blood pressure (see also Chapter 12); Clinical trials of atherosclerosis, lipid lowering, and statins (see also Chapter 12)
Clinical trials of acute myocardial infarction, coronary thrombosis, aspirin, and fibrinolysis (see also Chapter 4)Conducting reliable trials: issues of size and simplicity; Costs, cost-effectiveness, and health economics; Practical issues: managing a trial, funding, and regulation; What does the future hold?; References; CHAPTER 2: Publishing results of clinical trials and reviewing papers for publication; General considerations; Authorship; Title; Manuscript structure; Abstract; Introduction; Methods; Results, tables, and figures; Discussion; Database searches; References
Reviewing a submitted article for a journalIntegrity of the data and novelty of the results; Generalizability; Appropriateness of the study design; Scientific value of hypothesis and validity study results; Adequateness of methods; Ethical issues, plagiarism, and publication fraud; Language style, formatting, and presentation of data; Adequateness of citation; Recommendation to accept or decline the manuscript; References; CHAPTER 3: Management of chronic coronary artery disease; Introduction; Definition and classification; Pathophysiology; Medical management of myocardial ischemia
Lifestyle changes
Record Nr. UNINA-9910141393203321
Chichester, West Sussex, : Wiley-Blackwell, 2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Cardiovascular clinical trials : putting the evidence into practice / / edited by Marcus Flather, Deepak L. Bhatt, Tobias Geisler
Cardiovascular clinical trials : putting the evidence into practice / / edited by Marcus Flather, Deepak L. Bhatt, Tobias Geisler
Edizione [1st ed.]
Pubbl/distr/stampa Chichester, West Sussex, : Wiley-Blackwell, 2012
Descrizione fisica 1 online resource (413 p.)
Disciplina 616.100724
Altri autori (Persone) FlatherM
BhattDeepak L
GeislerTobias
Soggetto topico Cardiovascular system - Diseases - Treatment
Cardiology, Experimental
ISBN 1-283-60427-2
1-118-39937-4
9786613916723
1-118-39935-8
1-118-39934-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Title page; Copyright page; Contents; List of Contributors; Preface; List of Abbreviations; CHAPTER 1: Introduction to randomized clinical trials in cardiovascular disease; What is a randomized clinical trial?; Concept of randomization; Clinical trial phases; Preclinical studies; Phase 1 clinical trials; Phase 2 clinical trials; Phase 3 clinical trials; Phase 4 clinical trials; Study objective; Study populations; Efficacy variables; Surrogate variables; Control groups; Placebo-controlled trials; Active-control trials; Study design (bias); Methods of randomization; Minimization
Random and systematic errorStudy design issues to overcome systematic bias; Blinding; Study design (samples); Comparisons; Trials to show superiority; Trials to show equivalence or non-inferiority; Trials to show a dose-response relationship; Study protocol; Trial monitoring; Data monitoring; Data analysis sets; Intention-to-treat analysis and data set; Per protocol analysis and on-treatment analysis data sets; Subgroup analysis data sets; Unit of analysis; Missing data; Sensitivity analysis; Analysis methods; Demographic and other baseline characteristics
Measurements of treatment complianceAnalysis of efficacy; Distribution of data; Statistical analysis of clinical trials (elementary concepts); Adjustments for covariates; Time to event ("survival") analysis; Sample size and power; Safety evaluation; Subsets and more; Types of significance; Statistical significance; Practical or "clinical" significance; How have trials contributed to medical care?; Clinical trials for treatment of high blood pressure (see also Chapter 12); Clinical trials of atherosclerosis, lipid lowering, and statins (see also Chapter 12)
Clinical trials of acute myocardial infarction, coronary thrombosis, aspirin, and fibrinolysis (see also Chapter 4)Conducting reliable trials: issues of size and simplicity; Costs, cost-effectiveness, and health economics; Practical issues: managing a trial, funding, and regulation; What does the future hold?; References; CHAPTER 2: Publishing results of clinical trials and reviewing papers for publication; General considerations; Authorship; Title; Manuscript structure; Abstract; Introduction; Methods; Results, tables, and figures; Discussion; Database searches; References
Reviewing a submitted article for a journalIntegrity of the data and novelty of the results; Generalizability; Appropriateness of the study design; Scientific value of hypothesis and validity study results; Adequateness of methods; Ethical issues, plagiarism, and publication fraud; Language style, formatting, and presentation of data; Adequateness of citation; Recommendation to accept or decline the manuscript; References; CHAPTER 3: Management of chronic coronary artery disease; Introduction; Definition and classification; Pathophysiology; Medical management of myocardial ischemia
Lifestyle changes
Record Nr. UNINA-9910828067003321
Chichester, West Sussex, : Wiley-Blackwell, 2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Platelets in cardiovascular disease [[electronic resource] /] / editor, Deepak L. Bhatt
Platelets in cardiovascular disease [[electronic resource] /] / editor, Deepak L. Bhatt
Pubbl/distr/stampa London, : Imperial College Press, 2008
Descrizione fisica xv, 218 p. : ill
Disciplina 615/.71
Altri autori (Persone) BhattDeepak L
Soggetto topico Cardiovascular agents
Blood platelets
Cardiovascular system - Diseases
Soggetto genere / forma Electronic books.
ISBN 1-281-86767-5
9786611867676
1-86094-852-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Platelet biology: the role of platelets in hemostasis, thrombosis and inflammation / Richard C. Becker -- 2. Thromboxane antagonists / Brian R. Dulin and Steven R. Steinhubl -- 3. Glycoprotein IIb/IIIa inhibitors / Sam J. Lehman, Derek P. Chew and Harvey D. White -- 4. ADP receptor antagonists / Juhana Karha and Christopher P. Cannon -- 5. Monitoring antiplatelet therapy / Paul Harrison and Alan D. Michelson -- 6. Platelet genomics / Brian K. Jefferson, Kandice Kottke-Marchant and Eric J. Topol -- 7. Future strategies for the development of antiplatelet drugs / Robert A. Harrington.
Record Nr. UNINA-9910453550003321
London, : Imperial College Press, 2008
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Platelets in cardiovascular disease [[electronic resource] /] / editor, Deepak L. Bhatt
Platelets in cardiovascular disease [[electronic resource] /] / editor, Deepak L. Bhatt
Pubbl/distr/stampa London, : Imperial College Press, 2008
Descrizione fisica xv, 218 p. : ill
Disciplina 615/.71
Altri autori (Persone) BhattDeepak L
Soggetto topico Cardiovascular agents
Blood platelets
Cardiovascular system - Diseases
ISBN 1-281-86767-5
9786611867676
1-86094-852-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Platelet biology: the role of platelets in hemostasis, thrombosis and inflammation / Richard C. Becker -- 2. Thromboxane antagonists / Brian R. Dulin and Steven R. Steinhubl -- 3. Glycoprotein IIb/IIIa inhibitors / Sam J. Lehman, Derek P. Chew and Harvey D. White -- 4. ADP receptor antagonists / Juhana Karha and Christopher P. Cannon -- 5. Monitoring antiplatelet therapy / Paul Harrison and Alan D. Michelson -- 6. Platelet genomics / Brian K. Jefferson, Kandice Kottke-Marchant and Eric J. Topol -- 7. Future strategies for the development of antiplatelet drugs / Robert A. Harrington.
Record Nr. UNINA-9910782274403321
London, : Imperial College Press, 2008
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Platelets in cardiovascular disease / / editor, Deepak L. Bhatt
Platelets in cardiovascular disease / / editor, Deepak L. Bhatt
Edizione [1st ed.]
Pubbl/distr/stampa London, : Imperial College Press, 2008
Descrizione fisica xv, 218 p. : ill
Disciplina 615/.71
Altri autori (Persone) BhattDeepak L
Soggetto topico Cardiovascular agents
Blood platelets
Cardiovascular system - Diseases
ISBN 1-281-86767-5
9786611867676
1-86094-852-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Platelet biology: the role of platelets in hemostasis, thrombosis and inflammation / Richard C. Becker -- 2. Thromboxane antagonists / Brian R. Dulin and Steven R. Steinhubl -- 3. Glycoprotein IIb/IIIa inhibitors / Sam J. Lehman, Derek P. Chew and Harvey D. White -- 4. ADP receptor antagonists / Juhana Karha and Christopher P. Cannon -- 5. Monitoring antiplatelet therapy / Paul Harrison and Alan D. Michelson -- 6. Platelet genomics / Brian K. Jefferson, Kandice Kottke-Marchant and Eric J. Topol -- 7. Future strategies for the development of antiplatelet drugs / Robert A. Harrington.
Record Nr. UNINA-9910825818903321
London, : Imperial College Press, 2008
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui