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Molecular imaging through magnetic resonance for clinical oncology [[electronic resource] /] / Karen Belkic
| Molecular imaging through magnetic resonance for clinical oncology [[electronic resource] /] / Karen Belkic |
| Autore | Belkic Karen |
| Pubbl/distr/stampa | Cambridge, : Cambridge International Science Publishing, 2004 |
| Descrizione fisica | 1 online resource (348 p.) |
| Disciplina | 616.07548 |
| Soggetto topico |
Diagnostic imaging
Magnetic resonance |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-36120-4
9786610361205 1-904602-86-X 1-4237-4736-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910450177403321 |
Belkic Karen
|
||
| Cambridge, : Cambridge International Science Publishing, 2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular imaging through magnetic resonance for clinical oncology [[electronic resource] /] / Karen Belkic
| Molecular imaging through magnetic resonance for clinical oncology [[electronic resource] /] / Karen Belkic |
| Autore | Belkic Karen |
| Pubbl/distr/stampa | Cambridge, : Cambridge International Science Publishing, 2004 |
| Descrizione fisica | 1 online resource (348 p.) |
| Disciplina | 616.07548 |
| Soggetto topico |
Diagnostic imaging
Magnetic resonance |
| ISBN |
1-280-36120-4
9786610361205 1-904602-86-X 1-4237-4736-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910783478103321 |
|
Belkic Karen
|
||
| Cambridge, : Cambridge International Science Publishing, 2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular imaging through magnetic resonance for clinical oncology [[electronic resource] /] / Karen Belkic
| Molecular imaging through magnetic resonance for clinical oncology [[electronic resource] /] / Karen Belkic |
| Autore | Belkic Karen |
| Pubbl/distr/stampa | Cambridge, : Cambridge International Science Publishing, 2004 |
| Descrizione fisica | 1 online resource (348 p.) |
| Disciplina | 616.07548 |
| Soggetto topico |
Diagnostic imaging
Magnetic resonance |
| ISBN |
1-280-36120-4
9786610361205 1-904602-86-X 1-4237-4736-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- About the author -- CONTENTS -- Preface -- 1. Introduction: Molecular Imaging and Oncology -- 1.1 Functional plus anatomic imaging: The importance of combined modalities for oncology -- 1.2 Spectroscopic imaging through MR: Possibilities to be fully tapped for clinical oncology -- 1.3 Objectives, scope and organization of this book -- Part A BRIEF OVERVIEW OF BASIC PRINCIPLES -- 2. Magnetic Resonance -- 2.1 Precession: Response of 1H and some other nuclei to a static external magnetic field -- 2.2 Response to 90o radio-frequency pulse: Resonance and relaxation -- 2.3 Technical Considerations -- 3. In vivo Magnetic Resonance Spectroscopy -- 3.1 Chemical shift as the basis for identifying metabolites via a frequency spectrum -- 3.2 Characteristics of the metabolites evaluated by MRS -- 3.3 1H (proton) MRS -- 3.4 31 P MRS -- 3.5 MRS of a single volume -- 3.6 Magnetic field inhomogeneity -- 4. Signal Processing for Magnetic Resonance: The Basics -- 4.1 The concept of conjugate variables: Complementary representations -- 4.2 From the time to the frequency domain -- 4.3 Spatial localization: from the momentum to the coordinate representations -- 4.4 A brief mathematical background -- 5. Magnetic Resonance Spectroscopic Imaging -- 5.1 Spatial resolution of spectra -- 5.2 Implementation of MRSI -- 6. Safety Considerations in Magnetic Resonance -- 6.1 Effects of exposure to electromagnetic fields and other risks related to magnetic resonance -- 6.2 Precautions in magnetic resonance -- 6.3 Contraindications to magnetic resonance -- Part B MRS and MRSI -- Current State of the Art in Clinical Oncology -- 7. Magnetic Resonance in Cancer Diagnostics: Generalities -- 7.1 Relaxation rates of neoplastic tissues -- 7.2 Contrast Enhancement -- 7.3 Informative metabolites and metabolite ratios from in vivo MRS for cancer diagnostics.
7.4 MRSI-Importance of full volumetric coverage -- 8. Brain Tumors -- 8.1 Overview of epidemiological & -- clinical aspects -- 8.2 Magnetic resonance imaging in brain tumor diagnostics -- 8.3 Primary diagnosis of brain tumors using in vivo 1H-MRS-MRSI -- 8.4 In vivo MRS and MRSI for brain tumor grading -- 8.5 MRS & -- MRSI for histopathologic classification -- 8.6 MRSI for localization of brain tumors -- 8.7 Gauging response to therapy by MRS & -- MRSI -- 8.8 Prognostic information provided by MRSI -- 8.9 2D J-resolved and in vitro MRS: Further insight into the metabolic characteristics of brain tumors -- 9. Prostate Cancer -- 9.1 Overview of epidemiological & -- clinical aspects -- 9.2 MR-assisted prostate cancer diagnostics -- 9.3 MRI and MRSI for treatment planning -- 9.4 Follow-up with MRI & -- MRSI after treatment -- 9.5 2D COSY & -- in vitro MRS in prostate cancer -- 10. Gynecologic Cancers -- 10.1 Ovarian Cancer -- 10.2 Cancer of the Uterine Cervix -- 10.3 Endometrial Cancer -- 10.4 Comment on difference in approach to gender-specific cancers using MRS and MRSI -- 11. Head and Neck Cancers -- 11.1 Overview of epidemiological & -- clinical aspects -- 11.2 Anatomical and Functional Imaging -- 12. Non-Hodgkin's Lymphoma -- 12.1 Overview of epidemiological & -- clinical aspects -- 12.2 Anatomical and Functional Imaging -- 13. Sarcomas-Musculoskeletal Tumors -- 13.1 Overview of epidemiological & -- clinical aspects -- 13.2 Current approach to 1° diagnosis & -- staging -- 13.3 MRS in the assessment of sarcomas -- 14. Renal Cell Carcinomas -- 14.1 Overview of epidemiological & -- clinical aspects -- 14.2 Current approach to 1° diagnosis & -- staging -- 14.3 Initial studies using in vivo MRS -- 15. Hepatic, Gastrointestinal and other Tumors. 15.1 Functional Anatomical Imaging using PET and advanced CT-based methods -- 15.2 MRI and MRS in hepatic cancers -- 15.3 MR diagnostics in colorectal cancer -- 15.4 MR diagnostics in gastric cancer -- 15.5 MR diagnostics in esophageal cancer -- 15.6 MR diagnostics in pancreatic cancer -- 15.7 In Vitro MRS applied to some other cancers -- 16. Breast Cancer: Screening and Early Detection -- 16.1 Overview of epidemiological & -- clinical aspects -- 16.2 Breast cancer screening with mammography -- 16.3 Molecular imaging with FDG-PET and scintimammography -- 16.4 Magnetic resonance: Early results in 1° breast cancer diagnosis -- Part C Future Perspectives for MRS and MRSI in Cancer Diagnostics -- 17. Limitations of MRS / MRSI in Oncology: Relation to Reliance on the Conventional Framework for Data Analysis -- 17.1 Low Resolution of FFT -- 17.2 Poor signal-to-noise ratio of FFT -- 17.3 The FFT supplies only a shape spectrum -- 17.4 FFT requires for fitting, which is non-unique, the number of metabolites are guessed in advance -- 17.5 Small number of observable compounds on MRS revealed with FFT -- 18. Mathematical Advances in Spectral Analysis: Relevance for MRS/MRSI Cancer Diagnostics -- 18.1 The fast Padé transform has rapid, stable convergence -- 18.2 The FPT improves resolution and SNR -- 18.3 The FPT determines the exact number of metabolites -- 18.4 The FPT treats both Lorentzian and non- Lorentzian spectra on the same footing -- 18.5 The FPT can unambiguously identify overlapping resonances -- 18.6 The FPT accurately estimates concentrations -- 18.7 An illustration of the performance of the FPT for a clinical MRS signal -- 18.8 Validity of the FPT-Error analysis -- 18.9 Appropriateness of the FPT for tumor diagnostics within magnetic resonance -- 19. Next Needed Steps: Padé-Based Optimization of MRS and MRSI in Cancer Diagnostics. 19.1 View to early detection / screening -- 20. Concluding Comments and Outlooks: Prevention, Early Detection & -- Monitoring Cancer in a more Comprehensive Perspective -- 20.1 Emphasis upon quality of life -- Appendix 1 Glossary of Some Terms Relevant to MRS and MRSI -- Appendix 2 List of Acronyms. |
| Record Nr. | UNINA-9910816208203321 |
|
Belkic Karen
|
||
| Cambridge, : Cambridge International Science Publishing, 2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||