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Alzheimer’s Disease Research : What Has Guided Research So Far and Why It Is High Time for a Paradigm Shift / / by Christian Behl
| Alzheimer’s Disease Research : What Has Guided Research So Far and Why It Is High Time for a Paradigm Shift / / by Christian Behl |
| Autore | Behl Christian |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (XXV, 652 p. 116 illus., 107 illus. in color.) |
| Disciplina |
612.8
616.83110072 |
| Soggetto topico |
Neurosciences
Neurology Nervous system - Diseases Cognitive neuroscience Neurophysiology Learning - Physiological aspects Memory - Physiological aspects Neuroscience Neurological Disorders Cognitive Neuroscience Learning and Memory |
| ISBN | 3-031-31570-7 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1. Introduction -- Chapter 2. The Psychiatrist and Pathologist Aloysius Alzheimer and His Seminal Findings -- Chapter 3. Alzheimer’s Disease Research After 1945: The Recommencement -- Chapter 4. Alzheimer’s Research Goes Deeper – Ultrastructural Electron Microscopy Studies -- Chapter 5. Focus on Neurochemistry Led to the Cholinergic Hypothesis of Alzheimer’s Disease -- Chapter 6. The Glutamatergic-Hypothesis of Alzheimer’s Disease -- Chapter 7. Biochemistry and Genetics Points Out a Prime Suspect for Causing Alzheimer’s Disease -- Chapter 8. Getting to the Bottom of It: Amyloid Beta Peptide Is Derived from a Larger Precursor -- Chapter 9. Step by Step Towards an Amyloid Beta Peptide-Based Hypothesis of Alzheimer’s Disease -- Chapter 10. Concerns about the Amyloid Cascade Hypothesis and Reappraisals -- Chapter 11. Ignorance or Conspiracy? Or Just an Amyloid Firewall that Blocks Alternative Ideas? -- Chapter 12. In the Slip Stream of Amyloid: The Tau and Tangle Hypothesis -- Chapter 13. Focus on Tauopathies and Beyond -- Chapter 14. Alzheimer’s Research Gains Momentum and Spreads Out -- Chapter 15. The Amyloid Cascade Hypothesis Has to Deliver, Finally -- Chapter 16. Beyond APP, PSEN1, PSEN2, and APOE: What Else Does the Genome Tell Us? Chapter 17. Alternative Hypotheses and Observations that were Somehow Lost on the Way -- Chapter 18. Is the Persistence of the Amyloid Cascade Hypothesis a Result of Constant Confirmation Bias? -- Chapter 19. Driving Forces of Alzheimer’s Research Directions -- Chapter 20. Thirty Years after the Launch of the Amyloid Cascade Hypothesis: Is There a Shift of Gears at Last? -- Chapter 21. "If You Change the Way You Look at Things, Things You Look at Change". |
| Record Nr. | UNINA-9910734833403321 |
Behl Christian
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| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cell Aging: Molecular Mechanisms and Implications for Disease / / by Christian Behl, Christine Ziegler
| Cell Aging: Molecular Mechanisms and Implications for Disease / / by Christian Behl, Christine Ziegler |
| Autore | Behl Christian |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (113 p.) |
| Disciplina | 571.6 |
| Collana | SpringerBriefs in Molecular Medicine |
| Soggetto topico |
Molecular biology
Cytology Pathology Molecular Medicine Cell Biology |
| ISBN | 3-642-45179-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Aging and cell aging: an introduction -- Cell cycle: the life cycle of a cell -- Theories and mechanisms of aging -- Selected age-related disorders. |
| Record Nr. | UNINA-9910298301003321 |
|
Behl Christian
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| Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molekulare Mechanismen der Zellalterung und ihre Bedeutung für Alterserkrankungen des Menschen / / von Christian Behl, Christine Ziegler
| Molekulare Mechanismen der Zellalterung und ihre Bedeutung für Alterserkrankungen des Menschen / / von Christian Behl, Christine Ziegler |
| Autore | Behl Christian |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer Spektrum, , 2016 |
| Descrizione fisica | 1 online resource (128 p.) |
| Disciplina | 570 |
| Soggetto topico |
Cytology
Molecular biology Pathology Cell Biology Molecular Medicine |
| ISBN | 3-662-48250-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ger |
| Nota di contenuto | Einführung -- Der Zellzyklus: Lebenszyklus einer Zelle -- Theorien und Mechanismen des Alterns -- Ausgewählte altersbedingte Erkrankungen. |
| Record Nr. | UNINA-9910485015903321 |
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Behl Christian
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| Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer Spektrum, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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