Theranostics, Gallium-68, and Other Radionuclides [[electronic resource] ] : A Pathway to Personalized Diagnosis and Treatment / / edited by Richard P. Baum, Frank Rösch |
Edizione | [1st ed. 2013.] |
Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013 |
Descrizione fisica | 1 online resource (567 p.) |
Disciplina |
610.28/4
610.284 |
Collana | Recent Results in Cancer Research |
Soggetto topico |
Oncology
Nuclear medicine Neuroradiology Radiotherapy Molecular biology Oncology Nuclear Medicine Molecular Medicine |
ISBN |
1-283-61262-3
9786613925077 3-642-27994-5 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Theranostics, Gallium-68,and Other Radionuclides; Contents; Part IGenerators; 1 68Ge/68Ga Generators: Past, Present, and Future; Abstract; 1...Introduction; 2...The Early Years (1960--1970): The Dawn of 68Ga; 2.1 Further Generator Developments: Al2O3-Based EDTA-Eluted Generators; 2.2 68Ga-EDTA: The PET Pharmaceutical, Development of Positron Scintillation Cameras; 3...Hibernating 68Ga Medical Applications, but New Chemistry Ahead; 4...Commercial ''Ionic'' Generators; 5...Current State/Outlook; References; 2 Overview and Perspectives on Automation Strategies in 68Ga Radiopharmaceutical Preparations
Abstract1...Introduction; 2...Approach to Automation: Considerations on 68Ga Radiolabeling Process; 3...Modules for 68Ga Radiopharmaceuticals; 3.1 Classification and Characteristics of Automated Systems; 3.2 Automation and Regulatory Aspects; 4...Perspectives; References; 3 Post-Processing via Cation Exchange Cartridges: Versatile Options; Abstract; 1...Introduction; 2...The Initial Cation Exchange-Based Post-Purification Concept; 3...Combined Cation and Anion Exchange-Based Post-Processing; 4...Post-Processing Towards Nonaqueous Systems for Labeling Lipophilic Compounds 5...Instant Quantification of Generator 68Ge Breakthrough6...Conclusions; References; 4 68Ga Generator Integrated System: Elution--Purification--Concentration Integration; Abstract; 1...Introduction; 2...Nuclear Characteristics and Radioactive Transformation Equilibrium; 3...68Ge/68Ga Separation and 68Ga Generator; 3.1 Nanocrystalline Ceramic Structure Sorbent Used for Chromatographic 68Ge/68Ga Separation; 3.2 68Ga Generator Setup; 3.3 Generator Operation and Specification; 3.4 68Zn2+ Formation and Its Influence on Coordination Chemistry of 68Ga-Radiolabeling 4...Post-Elution Purification--Concentration of 68Ga Eluate4.1 Salt-Form Cationic Exchange Resin-Based Purification--Concentration Method; 4.2 Automation Process and Setup of 68Ga Radioisotope Generator Integrated System (RADIGIS-68Ga); 4.3 Basic/Acidic 68Ga Eluates and Their Radiolabeling; 4.4 Performance of 68Ga Generator and 68Ga Radioisotope Generator Integrated System; 5...Quality Evaluation Experiments: Quality Control Protocols and Radiolabeling Efficacy Evaluation; 5.1 Quality Evaluation of 68Ga Solution; 5.1.1 Quality Control Procedures 5.1.2 Radiolabeling Efficacy Evaluation Based on Radiolabeling Ligands DOTATOC and DOTATATE with 68Ga Solution5.2 Operation Performance Assessment of Ga-68 Generator Systems; Acknowledgments; References; 5 Purification and Labeling Strategies for 68Ga from 68Ge/68Ga Generator Eluate; Abstract; 1...Introduction; 1.1 History; 1.2 Current State; 1.3 Basic Methods; 1.3.1 Anionic Purification; 1.3.2 Cationic Purification; 1.3.3 Fractional Elution; 2...Combined Cationic--Anionic Purification of 68Ge/68Ga Generator Eluate for Labeling of Fragile Peptides and Proteins; 2.1 Aim; 2.2 Description 2.3 Advantages |
Record Nr. | UNINA-9910438129103321 |
Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013 | ||
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Lo trovi qui: Univ. Federico II | ||
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Therapeutic Nuclear Medicine [[electronic resource] /] / edited by Richard P. Baum |
Edizione | [1st ed. 2014.] |
Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014 |
Descrizione fisica | 1 online resource (922 p.) |
Disciplina | 616.07575 |
Collana | Radiation Oncology |
Soggetto topico |
Radiology
Nuclear medicine Oncology Imaging / Radiology Nuclear Medicine Oncology |
ISBN | 3-540-36719-5 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | PART I: Basic Principles (11 chapters) -- PART II: Clinical Applications: Brain and Nasopharyngeal Tumors (4 chapters).-Thyroid Cancer (11 chapters) -- Benign Thyroid Diseases (2 chapters) -- Primary and Metastatic Liver Cancer (5 chapters) -- Bone and Joint Disease (5 chapters) -- Hematological Malignancies (8 chapters) -- Endocrine Tumors (2 chapters) -- Radioimmunotherapy (7 chapters) -- Intravascular/Intracavitary/Interstitial and Epidemal RadionuclideTherapy (5 chapters) -- PART III: Radiation Biology and Dosimetry (11 chapters) -- PART IV: Radiation Planning and Perspectives of Radionuclide Therapy (10 chapters) -- Subject Index. |
Record Nr. | UNINA-9910300349803321 |
Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014 | ||
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Lo trovi qui: Univ. Federico II | ||
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