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Estrogen effects on traumatic brain injury : mechanisms of neuroprotection and repair / / edited by Kelli Duncan ; contributors Marco Avila-Rodriguez [and twenty eight others]
| Estrogen effects on traumatic brain injury : mechanisms of neuroprotection and repair / / edited by Kelli Duncan ; contributors Marco Avila-Rodriguez [and twenty eight others] |
| Pubbl/distr/stampa | London, England : , : Academic Press, , 2015 |
| Descrizione fisica | 1 online resource (172 p.) |
| Disciplina | 618.175061 |
| Soggetto topico | Estrogen - Therapeutic use |
| ISBN | 0-12-801707-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Estrogen Effects on Traumatic Brain Injury; Copyright Page; Contents; About the Editor; List of Contributors; About the Contributors; Taura Barr; George E. Barreto; Suzanne R. Burstein; Francisco Capani; Laura L. Carruth; Nicolas Diotel; Miranda Reed; Colin J. Saldanha; James Simpkins; Farida Sohrabji; Introduction; Why Should I Care?; Rationale and Scope of the Book; 1 Historical Antecedents; Introduction; The "INS AND OUTS" of TBI: An Overview; A History of TBI from Antiquity Through the 19th Century; From the Bench to the Clinic: TBI in the 20th and 21st Century
Conclusions and Future ThoughtsAcknowledgements; References; 2 Estrogen Actions in the Brain; Introduction; Steroid Hormones; Estrogens; Estrogen Receptors; Blood-Brain Barrier and Glial Cells; Estradiol and Brain Sexual Differentiation; Rapid Estrogen Signaling in the Brain; Estrogen-Sensitive Brain Regions; Sexually Dimorphic Brain Regions; Hippocampus; Cerebellum; Neurotransmitter Systems; Basal Forebrain Cholinergic System; Midbrain and Brainstem Serotonergic System; Catecholaminergic Neurons; Estrogens, Aging, and Neuroprotection; Additional Physiological Effects of Estrogens on the Body Conclusions and New DirectionsReferences; 3 Induction of Estrogen Response Following Injury; Introduction; Reactive Gliosis Following Injury; New Roles for Glial Cells as Steroid Synthesizing Cells; Induction of Glial Aromatase Following Injury; Neuroinflammation Induces Glial Aromatase Independent of Injury; Sex Differences in Cytokine Response Following Injury; Sex Differences in Glial Aromatase Expression Following Injury; Conclusion and Future Directions; Acknowledgements; References; 4 Astrocytic Aromatization and Injury; Aromatase is Expressed in Astroglia What Induces Astrocytic Aromatase Expression?Glial Estrogen Synthesis and Neuroprotection; Apoptosis and Secondary Degeneration; Injury-Induced Cyto- and Neurogenesis; Summary and Future Directions; Further Reading; 5 Aromatase and Estrogens: Involvement in Constitutive and Regenerative Neurogenesis in Adult Zebrafish; Introduction; Unique Features Exhibited by the Brain of Teleost Fish; Neurosteroid Synthesis and Signaling in the Brain of Adult Zebrafish; Aromatase B Expression is Restricted to Radial Glia Acting Like Neural Stem Cells Involvement of Aromatase and Estrogens in Adult Neurogenesis and Brain Repair in ZebrafishComparison with Mammalian and Nonmammalian Models; Hypothesis and Perspectives for Estrogen Involvement in Neurogenesis Regarding New Advances in Zebrafish and New Literature...; Conclusion; References; 6 Neuroprotection by Exogenous Estrogenic Compounds Following Traumatic Brain Injury; Introduction; Neuroprotective Steroids; Estrogens, Progestagens and Androgens as Protective Compounds; Selective Estrogen Receptor Modulators; Selective Tissue Estrogenic Activity Regulator; TBI Protection Strategies Role of Neuroactive Steroids in TBI |
| Record Nr. | UNINA-9910787490803321 |
| London, England : , : Academic Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Estrogen effects on traumatic brain injury : mechanisms of neuroprotection and repair / / edited by Kelli Duncan ; contributors Marco Avila-Rodriguez [and twenty eight others]
| Estrogen effects on traumatic brain injury : mechanisms of neuroprotection and repair / / edited by Kelli Duncan ; contributors Marco Avila-Rodriguez [and twenty eight others] |
| Pubbl/distr/stampa | London, England : , : Academic Press, , 2015 |
| Descrizione fisica | 1 online resource (172 p.) |
| Disciplina | 618.175061 |
| Soggetto topico | Estrogen - Therapeutic use |
| ISBN | 0-12-801707-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Estrogen Effects on Traumatic Brain Injury; Copyright Page; Contents; About the Editor; List of Contributors; About the Contributors; Taura Barr; George E. Barreto; Suzanne R. Burstein; Francisco Capani; Laura L. Carruth; Nicolas Diotel; Miranda Reed; Colin J. Saldanha; James Simpkins; Farida Sohrabji; Introduction; Why Should I Care?; Rationale and Scope of the Book; 1 Historical Antecedents; Introduction; The "INS AND OUTS" of TBI: An Overview; A History of TBI from Antiquity Through the 19th Century; From the Bench to the Clinic: TBI in the 20th and 21st Century
Conclusions and Future ThoughtsAcknowledgements; References; 2 Estrogen Actions in the Brain; Introduction; Steroid Hormones; Estrogens; Estrogen Receptors; Blood-Brain Barrier and Glial Cells; Estradiol and Brain Sexual Differentiation; Rapid Estrogen Signaling in the Brain; Estrogen-Sensitive Brain Regions; Sexually Dimorphic Brain Regions; Hippocampus; Cerebellum; Neurotransmitter Systems; Basal Forebrain Cholinergic System; Midbrain and Brainstem Serotonergic System; Catecholaminergic Neurons; Estrogens, Aging, and Neuroprotection; Additional Physiological Effects of Estrogens on the Body Conclusions and New DirectionsReferences; 3 Induction of Estrogen Response Following Injury; Introduction; Reactive Gliosis Following Injury; New Roles for Glial Cells as Steroid Synthesizing Cells; Induction of Glial Aromatase Following Injury; Neuroinflammation Induces Glial Aromatase Independent of Injury; Sex Differences in Cytokine Response Following Injury; Sex Differences in Glial Aromatase Expression Following Injury; Conclusion and Future Directions; Acknowledgements; References; 4 Astrocytic Aromatization and Injury; Aromatase is Expressed in Astroglia What Induces Astrocytic Aromatase Expression?Glial Estrogen Synthesis and Neuroprotection; Apoptosis and Secondary Degeneration; Injury-Induced Cyto- and Neurogenesis; Summary and Future Directions; Further Reading; 5 Aromatase and Estrogens: Involvement in Constitutive and Regenerative Neurogenesis in Adult Zebrafish; Introduction; Unique Features Exhibited by the Brain of Teleost Fish; Neurosteroid Synthesis and Signaling in the Brain of Adult Zebrafish; Aromatase B Expression is Restricted to Radial Glia Acting Like Neural Stem Cells Involvement of Aromatase and Estrogens in Adult Neurogenesis and Brain Repair in ZebrafishComparison with Mammalian and Nonmammalian Models; Hypothesis and Perspectives for Estrogen Involvement in Neurogenesis Regarding New Advances in Zebrafish and New Literature...; Conclusion; References; 6 Neuroprotection by Exogenous Estrogenic Compounds Following Traumatic Brain Injury; Introduction; Neuroprotective Steroids; Estrogens, Progestagens and Androgens as Protective Compounds; Selective Estrogen Receptor Modulators; Selective Tissue Estrogenic Activity Regulator; TBI Protection Strategies Role of Neuroactive Steroids in TBI |
| Record Nr. | UNINA-9910807641103321 |
| London, England : , : Academic Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||