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Infection and autoimmunity / / edited by Yehuda Shoenfeld, Nancy Agmon-Levin, Noel R. Rose
| Infection and autoimmunity / / edited by Yehuda Shoenfeld, Nancy Agmon-Levin, Noel R. Rose |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | London, England : , : Academic Press, , 2015 |
| Descrizione fisica | 1 online resource (1071 p.) |
| Disciplina | 616.97/8 |
| Soggetto topico |
Autoimmune diseases - immunology
Infections - immunology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
0-444-63272-7
0-444-63269-7 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Infection and Autoimmunity; Copyright ; Contents ; Contributors ; Chapter 1: Introduction; 1. Introduction; 2. Rheumatic Fever, A Prime Example; 3. Guillain-Barré Syndrome, A Second Example; 4. Underlying Mechanisms; 5. Autoimmunity Vs. Autoimmune Disease: The Adjuvant Effect; 6. The Problems and the Promise; 7. Lessons of Molecular (Epitope) Mimicry; 8. Views of the Future; Acknowledgements; References; Chapter 2: Infections and Autoimmune Diseases: An Interplay of Pathogenic and Protective Links; 1. Introduction; 2. Pathogenic Roles of Infections; 2.1. Viruses; 2.2. Bacteria
2.3. Fungi2.4. Parasites; 3. Protective Role of Infections; References; Part 1: Mechanisms of Autoimmunity induction by infectious agents and vaccination; Chapter 3: Molecular Mimicry and Autoimmunity; 1. Introduction; 2. Common Infectious Agents and Their Roll in Setting Autoimmune Disorders; 2.1. Viruses; 2.2. Bacteria; 2.3. Parasites; 3. Neuro-Autoimmune Disease; 4. Endocrinological Autoimmune Disease; 5. Inflammatory Articular Disease; 6. Vasculitides; 6.1. Summary and Suggestions for the Future: `Control of Molecular mimicry; References Chapter 4: Epitope Spreading in Autoimmune Diseases1. Introduction; 2. Examples of Epitope Spreading in Autoimmune Diseases; 2.1. Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis; 2.2. Insulin-Dependent Diabetes Mellitus or Type I Diabetes; 2.3. Arthritis; 2.4. Systemic Lupus Erythematosus; 2.5. Other Autoimmune Diseases; 3. Mechanisms Underlying Epitope Spreading During the Course of an Autoimmune Disease; 3.1. Upregulation of the Display of Cryptic/Subdominant Epitopes Within a Self Antigen Under Inflammatory Conditions 3.2. Release of Self Antigens and Their Processing and Presentation Following Tissue Damage in the Course of a Microbial ...3.3. Post-Translational Modification of Antigens; 3.4. The Frequency and Avidity of Epitope-Specific Precursor T Cells Within the Mature T Cell Repertoire Favoring Respons...; 3.5. Presentation of Neo-Epitopes Within a Particular Self Antigen by the B Cells Specific for That Antigen; 3.6. The Influence of Antigen-Bound Antibodies on the Processing and Presentation of T Cell Epitopes Within That Antigen; 3.7. Antigen Cross-Presentation and Epitope Spreading 3.8. Site of Initiation of Epitope Spreading: Target Organ Versus the Periphery4. Physiological Significance of Epitope Spreading: Involvement of Epitope Spreading in the Pathogenesis of Autoimmune Di...; 5. Implications of Epitope Spreading in Immunotherapy of Autoimmune Diseases: Hindering vs. Facilitating the Control of t...; 6. Concluding Remarks; References; Chapter 5: CD5-Expressing B-1 Cells and Infection; 1. Introduction; 2. Characterization of CD5+ B Cells; 2.1. Origins of the Cells; 2.2. Functions of CD5+ B Cells; 2.3. Control of the CD5+ B Cell Population 3. CD5+ B Cells and Disease |
| Record Nr. | UNISA-996426329203316 |
| London, England : , : Academic Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Vaccines and autoimmunity / / edited by Yehuda Shoenfeld and Nancy Agmon-Levin
| Vaccines and autoimmunity / / edited by Yehuda Shoenfeld and Nancy Agmon-Levin |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, , [2015] |
| Descrizione fisica | 1 online resource (394 p.) |
| Disciplina | 614.47 |
| Soggetto topico |
Vaccination
Immunological adjuvants Autoimmunity |
| ISBN |
1-118-66349-7
1-118-66372-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Title Page; Copyright; Contents; Contributors; Chapter Introduction; References; Part I Mosaic of Autoimmunity; Chapter 1 Role of Adjuvants in Infection and Autoimmunity; Introduction; The different types of adjuvants; Aluminum salts; Oil-based adjuvants; Virosomes; Novel and experimental adjuvants; Mechanisms of adjuvanticity; Adjuvants and the adaptive and innate immune response; Adjuvants and TLRs; Mechanisms of adjuvant adverse effects; Autoimmunity and environmental/natural adjuvants; Adjuvant-related diseases; Mineral oils as a cause of autoimmunity
Human adjuvant disease, silicone as an adjuvant, and connective tissue diseasesMacrophagic myofasciitis and Gulf War syndrome; Autoimmune (autoinflammatory) syndrome induced by adjuvants - ASIA; Conclusions; References; Chapter 2 Infections as Adjuvants for Autoimmunity: The Adjuvant Effect; Introduction; The adjuvant effect; Innate immune pattern recognition of pathogens and adjuvants; Innate immune response mediates the adjuvant effect; Viral infection as adjuvant for autoimmunity: evidence from Coxsackievirus-induced myocarditis; ""Adjuvant disease"" Harnessing the adjuvant effect and autoimmunity against cancerConclusions; Acknowledgments; References; Chapter 3 Experimental Models of Adjuvants; Adjuvant models; Murine models; Rats; Mice; Salmon; Rabbits; Swine; Primates; Conclusions; References; Chapter 4 Answers to Common Misconceptions Regarding the Toxicity of Aluminum Adjuvants in Vaccines; Introduction; Al and neurological disorders; Al as adjuvant in vaccines; How is the safety of Al regulated?; Dietary versus vaccine-derived Al: is there a difference?; Long-term persistence of Al adjuvants in the body and its effects Al's activation of the NLRP3 inflammasome pathway and its role in autoimmune-inflammatory diseasesAl body burden and the health risks associated with life-long exposure to Al adjuvants; Conclusions; Acknowledgments; References; Chapter 5 Allergy and Autoimmunity Caused by Metals: A Unifying Concept; Introduction; Delayed-type hypersensitivity; The allergic and autoimmune effects of metals; Mercury; Gold; Nickel; Aluminum; Conclusions; References; Chapter 6 Genetics and Vaccinology; Introduction; Brief history of vaccinology; Vaccine response and genetics; Epidemiology and genetics Polymorphism of the HLA regionNon-HLA genetic polymorphisms and vaccine response; Conclusions; References; Chapter 7 Silicone and Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA); Introduction; Silicone; Autoimmune/inflammatory syndrome induced by adjuvants (ASIA); Silicone and autoimmunity; Local adverse effects of silicone; The systemic influence of silicone; Antibody response following silicone exposure; Silicone and defined autoimmune diseases; Silicone and scleroderma; Silicone and nondefined autoimmune phenomena; Conclusions; References Chapter 8 Silicone Breast Implants and Autoimmune/Inflammatory Syndrome induced by Adjuvants (ASIA): A Literature Search |
| Record Nr. | UNINA-9910140641403321 |
| Hoboken, New Jersey : , : John Wiley & Sons, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Vaccines and autoimmunity / / edited by Yehuda Shoenfeld and Nancy Agmon-Levin
| Vaccines and autoimmunity / / edited by Yehuda Shoenfeld and Nancy Agmon-Levin |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, , [2015] |
| Descrizione fisica | 1 online resource (394 p.) |
| Disciplina | 614.47 |
| Soggetto topico |
Vaccination
Immunological adjuvants Autoimmunity |
| ISBN |
1-118-66349-7
1-118-66372-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Title Page; Copyright; Contents; Contributors; Chapter Introduction; References; Part I Mosaic of Autoimmunity; Chapter 1 Role of Adjuvants in Infection and Autoimmunity; Introduction; The different types of adjuvants; Aluminum salts; Oil-based adjuvants; Virosomes; Novel and experimental adjuvants; Mechanisms of adjuvanticity; Adjuvants and the adaptive and innate immune response; Adjuvants and TLRs; Mechanisms of adjuvant adverse effects; Autoimmunity and environmental/natural adjuvants; Adjuvant-related diseases; Mineral oils as a cause of autoimmunity
Human adjuvant disease, silicone as an adjuvant, and connective tissue diseasesMacrophagic myofasciitis and Gulf War syndrome; Autoimmune (autoinflammatory) syndrome induced by adjuvants - ASIA; Conclusions; References; Chapter 2 Infections as Adjuvants for Autoimmunity: The Adjuvant Effect; Introduction; The adjuvant effect; Innate immune pattern recognition of pathogens and adjuvants; Innate immune response mediates the adjuvant effect; Viral infection as adjuvant for autoimmunity: evidence from Coxsackievirus-induced myocarditis; ""Adjuvant disease"" Harnessing the adjuvant effect and autoimmunity against cancerConclusions; Acknowledgments; References; Chapter 3 Experimental Models of Adjuvants; Adjuvant models; Murine models; Rats; Mice; Salmon; Rabbits; Swine; Primates; Conclusions; References; Chapter 4 Answers to Common Misconceptions Regarding the Toxicity of Aluminum Adjuvants in Vaccines; Introduction; Al and neurological disorders; Al as adjuvant in vaccines; How is the safety of Al regulated?; Dietary versus vaccine-derived Al: is there a difference?; Long-term persistence of Al adjuvants in the body and its effects Al's activation of the NLRP3 inflammasome pathway and its role in autoimmune-inflammatory diseasesAl body burden and the health risks associated with life-long exposure to Al adjuvants; Conclusions; Acknowledgments; References; Chapter 5 Allergy and Autoimmunity Caused by Metals: A Unifying Concept; Introduction; Delayed-type hypersensitivity; The allergic and autoimmune effects of metals; Mercury; Gold; Nickel; Aluminum; Conclusions; References; Chapter 6 Genetics and Vaccinology; Introduction; Brief history of vaccinology; Vaccine response and genetics; Epidemiology and genetics Polymorphism of the HLA regionNon-HLA genetic polymorphisms and vaccine response; Conclusions; References; Chapter 7 Silicone and Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA); Introduction; Silicone; Autoimmune/inflammatory syndrome induced by adjuvants (ASIA); Silicone and autoimmunity; Local adverse effects of silicone; The systemic influence of silicone; Antibody response following silicone exposure; Silicone and defined autoimmune diseases; Silicone and scleroderma; Silicone and nondefined autoimmune phenomena; Conclusions; References Chapter 8 Silicone Breast Implants and Autoimmune/Inflammatory Syndrome induced by Adjuvants (ASIA): A Literature Search |
| Record Nr. | UNINA-9910830374203321 |
| Hoboken, New Jersey : , : John Wiley & Sons, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||