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Pharmacogenetics to Avoid Adverse Drug Reactions
| Pharmacogenetics to Avoid Adverse Drug Reactions |
| Autore | López-Fernández Luis A |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (220 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
5-fluorouracil
capecitabine fluoropyrimidine thymidylate synthase thymidylate synthase enhancer region upstream stimulatory factor 1 adverse drug reactions pharmacogenomics epistasis random forest statin cardiovascular disease colorectal cancer personalised medicine toxicity (es)citalopram drug-gene-interaction drug-drug-interaction drug-drug-gene-interaction the PharmLines initiative antipsychotic agents pharmacogenetics cytochrome P-450 enzyme system psychotic disorders precision medicine direct oral anticoagulants clinical implementation atorvastatin SLCO1B1 HLA cutaneous adverse drug reaction SCAR genetic polymorphism antiepileptics CYP450 enzymes platelet reactivity single-nucleotide variants acute coronary syndrome clopidogrel genotype allele polymorphism HLA B CYP2C9*3 cutaneous adverse drug reactions (CADRs) anti-epileptic drugs (AEDS) phenytoin (PHT) genetic risk factors South India India cardiology adverse events guidelines |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557610103321 |
López-Fernández Luis A
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Plant Natural Products for Human Health
| Plant Natural Products for Human Health |
| Autore | Zhang Hongjie |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (514 p.) |
| Soggetto non controllato |
PhGs
bitter orange immunomodulator A549 cells bergapten triptolide BMP/Smad phytochemicals antioxidant enzymes kumquat MTT assay HepaRG cells human health nanoparticles dendritic cells drug discovery biofilm catechin antitubercular activity Panax notoginseng saponins animals mouse-hair growth A? curcumin WNT/?-catenin copaiba AD Plasmodium parasites traditional medicine procyanidin A2 PET inhibition rheumatoid arthritis cannabinoid type 1 receptor iridoids inflammatory bowel disease acute liver injury human-hair-follicle dermal papilla cells Neuroprotective dihydromyricetin AMPK thromboembolism ginseng drug design and development endoplasmic reticulum stress mitogen-activated protein kinase Nrf2 prenylated flavonoids inflammation preclinical studies plants dietary supplements Glycyrrhiza uralensis aspirin Tripterygium wilfordii P. eryngii reperfusion ethnopharmacology glucans innovation hpatoprotection hinokitiol phytocannabinoid antistaphylococcal activity Shh/Gli green tea sesquiterpenoids adjuvant-induced arthritis yuzu hepatotoxicity p53/Bax Keap1 nuclear factor-kappaB oxidative stress pharmacokinetic study cinnamamides toxicity APAP Astragali Radix computational softwares plant natural product onion anti-malaria activity lipogenesis bleeding time diterpenoids Penthorum chinense Pursh myocardial hypertrophy automation adjuvant grapefruit melanoma cell essential oil sweet orange Amadori rearrangement compounds heme oxygenase global health calorie restriction bergamot liposomes EGCG celastrol herb–drug interactions cannabigerol anti-inflammation OH· free radical molecular targets gluconeogenesis microbiome SIRT1 fucoidan heart PC12 cells acetaminophen omics time-kill assay arthritis lychee seed bioinformatics structure–activity relationship precision medicine orange petitgrain immune modulation antiproliferation flavonoids scoulerine oleoresin triterpenic acids Cannabis sativa NAFLD biological activity differentiation oxygen consumption rate mitochondrial bioenergetics neroli apoptosis targeted delivery platelet activation protein kinase heat-process hepatic steatosis hyperglycemia natural products lemon genistein neuroinflammation astragaloside IV cytoxicity flavonoid paracetamol medicinal plants insulin resistance resveratrol mandarin garlic TGF-? morin hydrate sirtuin 3 MMPs gomisin N lime Ziziphus jujuba antifungal activity ischemia migration caspases small molecules |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346688103321 |
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Zhang Hongjie
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Plant Responses and Tolerance to Metal/Metalloid Toxicity
| Plant Responses and Tolerance to Metal/Metalloid Toxicity |
| Autore | Hasanuzzaman Mirza |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (318 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Botany & plant sciences |
| Soggetto non controllato |
metal stress
toxicity silicon Si-fertilization genomics transporter genes cadmium toxicity oxidative stress antioxidative defense system photosynthetic pigments environmental pollution phytoextraction cadmium biostimulation oxidative damage metal toxicity sulphur nutrition stress mitigation cation exchange capacity glutathione agriculture Cd stress environmental gene expression PGPB switchgrass P. fasciculatum heavy metals tolerant plant protein carbonylation photosynthesis proteins mining soils thiols phenolic metabolites organic acids lead castor beans citric acid antioxidant enzyme antioxidant system ethylene glyoxalase system photosynthesis proline metabolism zinc jute varieties copper stress phytoremediation bioaccumulation factor translocation factor growth copper toxicity micronutrient deficiency iron nicotianamine histidine Cu-chelation lead pollution antioxidants bentonite grain biochemistry biochar maize hybrids nickel nutrients translocation heavy metal reactive oxygen species oxidative burst Rhododendron arboreum Vigna radiata enzymes activity chromium (Cr) polyphenols abiotic stress antioxidant defense methylglyoxal organic acid ripening physiology silver chemical elicitors chili fibrous crop environmental pollutants morphological traits soil remediation chelating agents chromium wastewater sunflower biomass chlorophyll contents |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557785903321 |
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Hasanuzzaman Mirza
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Polymer Materials in Biomedical Application
| Polymer Materials in Biomedical Application |
| Autore | Raza Faisal |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (254 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
hydrogels
crosslinking degradable gamma (γ)-irradiation sterilization sterility assurance antibacterial ability jojoba Simmondsia chemistry liquid wax biology toxicity pharmaceutical/industrial uses articular cartilage mechanical properties tribological properties antibacterial pathogens infectious diseases silver nanoparticles wound care wound dressings polymers gelatin nanofibers sponges Ag/RGO nanocomposites green preparation anticancer performance potential mechanism oxidative stress hydrogel poloxamer 407 polymer poloxamer 407 gel transungual drug delivery onychomycosis ungual penetration enhancer Terbinafine diafiltration SAXS aromatic interactions poly(sodium 4-styrenesulfonate) chlorpheniramine polyelectrolyte aggregation coaxial electrospinning extracellular matrix myelination oligodendrocyte water-soluble materials orthokeratology lens protein deposition optical characteristics rubbing chitosan kenaf nanocrystalline cellulose platelet lysate wound healing carbohydrate polymers blends functional food antioxidant activity co-microencapsulation spray drying bacteria viability (Bacillus clausii) probiotics itraconazole self-emulsifying nanovesicles transungual anti-fungal |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557613203321 |
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Raza Faisal
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Preparation, Physico-Chemical Properties and Biomedical Applications of Nanoparticles
| Preparation, Physico-Chemical Properties and Biomedical Applications of Nanoparticles |
| Autore | Cavalu Simona |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
titanium cranioplasty
endoprosthesis patented solutions amniotic membrane FTIR spectroscopy immunohistochemistry AFM UV light antibiotic pterygium surgery selenium nanoparticles Lactobacillus casei cadmium antioxidant enzymes liver histology anti-apoptotic anti-inflammatory endodontic sealer CNTs chlorhexidine silver nanoparticles antimicrobial liposomes hyaluronic acid full-factorial berberine bioavailability metal nanoparticles carbon-based nanomaterials screen-printed electrodes electrochemical (bio)sensors biomedical applications PMMA bone cements peppermint essential oil gentamicin antimicrobial properties nanomedicine nanoparticles phytomedicine bioinformatics neurodegenerative diseases silver gold nanocages in vitro bioactivity antibacterial activity electrospinning nanofibers implants wound healing targeted delivery biopolymers ZnO-NPs traditional synthesis green synthesis toxicity gatifloxacin cubosomal dispersion MIC corneal permeation methicillin resistant Staphylococcus aureus keratitis hepatocellular carcinoma cancer diagnosis targeting smart therapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580206203321 |
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Cavalu Simona
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Prevalence, Fate and Effects of Plastic in Freshwater Environments
| Prevalence, Fate and Effects of Plastic in Freshwater Environments |
| Autore | Khan Farhan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (84 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
plastics
plastic debris African great lakes freshwater beach clean-up citizen science microplastic Enchytraeus crypticus enchytraeids avoidance test toxicity oxidative stress catalase glutathione S-transferase polyethylene Tubifex tubifex aquatic oligochetes mortality glutathione reductase peroxidase microplastic exposure freshwater environments microplastics Africa ingestion Nile tilapia (Oreochromis niloticus) catfish (Bagrus Bajad) fibers ATR-FTIR spectroscopy plastic pollution oysters Mississippi Sound fluorescence microscopy laser direct infrared analysis LDIR bulk water sampling Bonnet Carré Spillway dysbiosis microbiome |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557334103321 |
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Khan Farhan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Renal Cell Carcinoma
| Renal Cell Carcinoma |
| Autore | López José I |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (500 p.) |
| Soggetto topico |
Renal cell carcinoma
Kidneys - Cancer |
| Soggetto non controllato |
N-glycomapping
SMAD proteins patient survival pro-IL-1? survival prediction inflammation markers tumor migration prognostic factors practical approach circular RNAs in a clinico-genomic predictive model glycomarkers review nephrectomy uric acid VEGF inhibitors metabolic reprogramming collecting duct carcinoma curcumin metabolome profiling identification of circular RNAs IL-2 experimental validation of circular RNA Raf/MEK/ERK HOT PI3K/Akt/mTOR pentose phosphate pathway kidney cancer LOT mutation RCC polybromo-1 pale cell MMP-9 gene expression recurrence free survival chromosomal loss IL-1? chronic kidney disease glutathione transferase omega 2 label-free glutathione transferase omega 1 emerging entity copy number alteration FOXO3 predictive role tumor slice culture tyrosine kinase inhibitors PPP ESC CDKN1A expression metastasis PD-L1 diagnostic and prognostic markers EVI1 copy number loss RNA sequencing NK cells glutathione metabolism clear cell renal cell carcinoma renal cell cancer proliferation eosinophilic variant Xp11 translocation renal cell carcinoma prognosis invasion immune infiltration IL4R? FISH 11) translocation renal cell carcinoma tumor microenvironment metabolome hyperosmolality toxicity ALK drug sensitivity t(6 copy number analysis urine genetic association polymorphism solute carrier proteins kidney metastatic ccRCC molecular genetic features recurrence-free survival chromophobe renal cell carcinoma unclassified renal tumor overall survival mTOR inhibitors mTOR JAK2 von Hippel-Lindau miR-155-5p glycoproteomics PBRM1 miR-133b survival TFE3 TFEB oncocytic renal tumor immune checkpoint inhibitors biomarker MMP10 TCGA ghrelin EMT like checkpoint inhibitors MiT family translocation renal cell carcinoma gene signature sarcomatoid transforming growth factor beta clear cell Renal Cell Carcinoma tumor adhesion renal cancer unclassified renal cell carcinoma Papillary renal cell carcinoma (pRCC) miR-146a-5p renal cell everolimus integrins cytoreductive nephrectomy immunotherapy predictive factors immunohistochemistry MTA2 IL13R?1 targeted therapy intratumour heterogeneity aurora A TCA cycle AMP-activated protein kinases cancer-specific survival programmed death-ligand 1 efficacy renal cell carcinoma anaplastic lymphoma kinase rearrangement TFEB-amplified renal cell carcinoma statins cancer immunotherapy microRNA new entity proteome profiling |
| ISBN | 3-03928-639-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404087003321 |
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López José I
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Natural Compounds in Inflammation and Inflammatory-Related Diseases
| Role of Natural Compounds in Inflammation and Inflammatory-Related Diseases |
| Autore | Maione Francesco |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (174 p.) |
| Soggetto non controllato |
toxicity
long-lasting effect iso-?-acids ammonium glycyrrhizinate metabolomics cytokines Alnus sibirica energy metabolism curcumin antineuroinflammation nitric oxide antioxidant nutraceutical food liver nardochinoid B endometriosis adipose tissue Nardostachys chinensis tau macrophage nociception heme oxygenase-1 enzymatic hydrolysis IL-6 nuciferine docking chronic nonbacterial prostatitis black tea polyphenol network pharmacology Tagetes patula L. SEM lipopolysaccharide solid lipid nanoparticle tauopathy memory lupane-type triterpene acute lung injury inducible nitric oxide synthase inflammation anti-inflammatory microglia resveratrol theaflavins hirsutanonol short-term high-fat diet inflammatory disease juçara oregonin PPARs NF-?B neuroprotection Portulaca oleracea TNF-? depression |
| ISBN | 3-03921-553-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367756703321 |
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Maione Francesco
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Roles and Functions of ROS and RNS in Cellular Physiology and Pathology
| Roles and Functions of ROS and RNS in Cellular Physiology and Pathology |
| Autore | Zarkovic Neven |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (230 p.) |
| Soggetto non controllato |
toxicity
toll-like receptors acrolein hydroxyapatite-based biomaterials LC-MS/MS blood–brain barrier NADPH-oxidase human neuroblastoma SH-SY5Y cells NRF2-NQO1 axis granulocytes free radicals antioxidant plaque vulnerability bEnd.3 relaxation Ca2+ keratinocytes oxidative metabolism of the cells lipid peroxidation intermittent hypoxia osteoblast growth UV radiation ROS bEnd5 cyclopurines NF?B glucose deprivation antimicrobial endothelial cells 4-hydroxynonenal (4-HNE) histamine glutamine deprivation optical coherence tomography antioxidants DNA damage glutathione NQO1 transcript variants xeroderma pigmentosum cancer cells VAS2870 reactive oxygen species (ROS) TP53 mutation DNA and RNA polymerases viability oxidative burst macrophages inflammation Nrf2 von Willebrand factor reactive oxygen species growth control intracellular signaling MFN2 nuclear factor erythroid 2–related factor 2 fusion/fission IMR-90 calcium proliferation mitochondria pathophysiology of oxidative stress redox balance 4-hydroxynonenal cannabidiol oxidative homeostasis rs1800566 neuronal cell death heme-oxygenase-1 vitamins cell signaling TRPM2 channel aorta cancer growth cancer regression oxidative stress nucleotide excision repair |
| ISBN | 3-03928-783-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404087603321 |
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Zarkovic Neven
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Selected Papers from XVI MaNaPro and XI ECMNP
| Selected Papers from XVI MaNaPro and XI ECMNP |
| Autore | Vasconcelos Vítor |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (214 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
marine-derived fungi
secondary metabolites polyketides drimanes meroterpenoids cytotoxicity benthic cyanobacteria tropical mangrove Guadeloupe phylogenetic diversity chemical diversity molecular networking antimicrobial activity proteasome inhibition dolabellane secosteroids soft coral marine natural products actinomycetes biofouling antifouling antibiofilm napyradiomycins hybrid isoprenoids drug discovery bioprospection Dysidea avara avarone/avarol redox-active compounds quinones and hydroquinones dioxothiazinoquinone Schistosoma mansoni Plasmodium falciparum Leishmania spp 3D-SAR analysis DFT studies PhenoTarget approach MRMS protein-ligand complex polycarpine holothurian diatom anti-fouling compounds saponins triterpene glycosides mass spectrometry Antarctica ascidian microbiome microbial diversity palmerolide A co-occurrence porphyrinoids annelida marine bioproducts HPLC-DAD toxicity photosensitizers chirality configurational analysis distance geometry NMR spectroscopy NOE data residual dipolar couplings Sarcophyton cherbonnieri cembranoid anti-inflammatory activity elastase release superoxide anion generation osteoarthritis amentadione preclinical osteoarthritis models marine compounds Cystoseira usneoides inflammation mineralization chondrocytes synoviocytes cartilage explants |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557670103321 |
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Vasconcelos Vítor
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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