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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (606 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
benzofurans
chemical synthesis cytotoxic properties HeLa MOLT-4 K562 anticancer anti-neuroinflammation coumarin dihydroartemisinin flavonoids allene E-stereoselective regioselective anti-cancer activity cyanopyridone substituted pyridine pyridotriazine pyrazolopyridine thioxotriazopyridine anticancer activity HepG2 antitumor activity computational docking MDM2-p53 interaction xanthones yeast-based assays estrone derivatives hydrazine N-substituted pyrazoline anti-ovarian cancer topoisomerase II inhibitor kinase inhibitor antiproliferative agent urea synthesis antiproliferative activity apoptosis indoleamine 2,3-dioxygenase inhibitor anti-tumor immune modulation tryptophan metabolism taxoids βIII-tubulin P-glycoprotein drug resistance thiopene thienopyrimidinone thiazolidinone breast cancer benzofuran–pyrazole nanoparticles cytotoxic activity PARP-1 inhibition 3,6-dibromocarbazole 5-bromoindole carbazole actin migration Thienopyrimidine Pyrazole PI3Kα inhibitor quinazolin-4(3H)-one quinazolin-4(3H)-thione Schiff base antioxidant activity DFT study ortho-quinones beta-lapachone tanshione IIA PI3Ks PI3Kδ inhibitors 2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide anticancer agents protein–protein interactions virtual screening mimetics drug discovery bivalency polyvalency antitumor cell cycle ovarian cancer P-MAPA IL-12 TLR signaling inflammation chemoresistance 4-(pyridin-4-yloxy)benzamide 1,2,3-triazole c-Met natural product anticancer agent zampanolide Talazoparib PARP inhibitor prodrug o-nitro-benzyl photoactivatable protecting groups salinomycin overcoming drug resistance tumor specificity synergy 5-fluorouracil gemcitabine amides/esters colchicine analogs thiocolchicine colchiceine antimitotic agents hydrates dihydropyranoindole HDAC inhibitors neuroblastoma aromatase MCF-7 NIH3T3 benzimidazole triazolothiadiazine docking ADME organosilicon compounds SILA-409 (Alis-409) SILA-421 (Alis-421) multidrug resistance (MDR) reversal ABCB1 (P-glycoprotein) colon cancer colchicine amide colchicine sulfonamide tubulin inhibitors docking studies crystal structure PROTACs protein degradation IGF-1R Src protein kinase phenylpyrazolopyrimidine enzyme inhibition molecular simulation androgen receptor prostate cancer enzalutamide apalutamide darolutamide triple-negative breast cancer cytotoxicity chrysin analogues flavonoid anticancer compounds |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Drugs 2021
| Anticancer Drugs 2021 |
| Autore | Meegan Mary J |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (594 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
thymidylate synthase
cytotoxicity 1,2,3-triazole 1,3,4-oxadiazole 5-fluoruracil pemetrexed docking 3,4'-bis-guanidino 3-amino-4'-guanidino diphenyl ether phenyl pyridyl ether intramolecular hydrogen bond cancer cell viability HL-60 BRAF apoptosis thieno[2,3-d][1,2,3]triazine acetamide H1299 HER2 EGFR Bcl-2 inhibitors Indole-based analogues benzimidazole MTT cytotoxic assay cell cycle analysis DNA fragmentation ELISA solid/lipid nanoparticles phenstatin letrozole tubulin polymerisation inhibitor aromatase inhibitor breast cancer hybrid molecule dual-targeting molecule designed multiple ligand NaMSA cyclophosphamide histopathology testis urinary bladder anticancer agents enantioselective synthesis gastric adenocarcinoma tryptophanol concentration-guided dosing model informed dosing physiologically based pharmacokinetics sorafenib tyrosil-DNA-phosphodiesterase 1 adamantane resin acid TDP1 cytotoxic agents apoptosis induction HT-29 cells MDA-MB-231 cells mechanism prediction STAT inhibitors miR-21 hydrazide derivatives nitrogen scaffolds mitoxantrone cardiotoxicity inflammation oxidative stress age cumulative dose Trk NTRK tissue-agnostic larotrectinib entrectinib Trk fusion protein kinase inhibitors USFDA cancer patent review generic product doxazosin MD simulations combretastatin A-4 cytotoxic activity hybrid compounds indazole mucin MUC1 MUC16 immunotherapy cancer vaccine CAR (chimeric antigen receptor) ADC (antibody-drug conjugate) thiourea interleukin-6 trypan blue assay chalcones exportin-1 covalent binding CovDock anticancer activity xanthone in vitro in vivo isolation synthesis heterocyclic compound benzenesulfonamides imidazoles alkylated colony formation tumor spheroids HDAC inhibitors chalcone dual inhibitors carvedilol kidney toxicity 7-deaza-4'-thioadenosine derivatives multi-kinase inhibitor anticancer nucleoside Imiquimod drug efflux multidrug resistance Toll-Like Receptor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576874303321 |
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Meegan Mary J
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antimicrobial Materials with Medical Applications
| Antimicrobial Materials with Medical Applications |
| Autore | Hadjikakou Sotiris |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Microbiology (non-medical) |
| Soggetto non controllato |
bisdemethoxycurcumin
curcumin curcuminoid demethoxycurcumin photodynamic inactivation Staphylococcus aureus Staphylococcus epidermis prosthetic joint infection fracture-related infection bone graft substitute revision arthroplasty local antibiotic antimicrobial activity oxo-titanium(IV) complexes polymer-inorganic composites physicochemical properties thermal properties multi-functionalized cellulose microfibers controlled release wound dressing antioxidant activity sericin AgNPs ZnO green synthesis cavity disinfection antimicrobial substances chlorhexidine adhesion bonding dental caries Cr2O3 Abutilon indicum (L.) Sweet antibacterial anticancer antioxidant biocompatibility metallic nanoparticles silver gold synthesis characterization surface reactivity stability antibacterial activity Escherichia coli multidrug resistant bacteria silver nanoparticles oregano leaves' extract antimicrobial materials hydrogels contact lens plasma electrolytic oxidation additive manufacturing titanium bone implants antibacterial biomaterials surface biofunctionalization implant-associated infection cavity disinfectants primary teeth bond strength face shield facial protective equipment SARS-CoV-2 phage phi 6 MRSA MRSE polyethylene terephthalate benzalkonium chloride COVID-19 multidrug-resistant bacteria bioreduction biocapping agent bionanofactories biomedical |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566478603321 |
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Hadjikakou Sotiris
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biosensors - Recent Advances and Future Challenges
| Biosensors - Recent Advances and Future Challenges |
| Autore | Katz Evgeny |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (504 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
metabolite sensors
sensor biocompatibility ion selective electrodes foreign body reaction O2 glucose lactate biosensors bioelectrochemistry photo-biosensors enzyme biocatalysis electrochemical biosensors real-time continuous operation reagentless reusable calibration-free antibiofouling biosensor biomimetic membranes membrane-bound enzymes electrodes sulfur-containing nanomaterials metallic sulfide nanomaterials sulfur-containing quantum dots enzyme-based biosensors direct electron transfer (DET) redox enzymes nanostructured electrodes protein film voltammetry (PFV) glucose biosensors nanoporous metals nanoporous gold graphene carbon nanotube ordered mesoporous carbon additive manufacturing heme peroxidases semiconductors peroxidase mimics DNA assay nucleic acid isothermal signal amplification restriction endonuclease wearable biosensors metabolism remote monitoring sweat microfluidic 3D printing nanoparticle nanocomposite nanozyme synthesis catalytic properties nano-peroxidase nanooxidase nanolaccase electronanocatalyst amperometric (bio)sensors POC microfluidics immunosensor cancer biomarkers electrochemical DNA sensor nucleic acid sensor DNA RNA pathogen sensing 2D-materials field-effect transistor transition metal dichalcogenides black phosphorus phosphorene hexagonal boron nitride transition metal oxides current-potential curve multi-enzymatic cascades multianalyte detection mass-transfer-controlled amperometric response potentiometric coulometry MXenes 2D nanomaterials wearables electrochemistry bacteria electrochemical ELISA electrochemical immunoassays electrochemical aptamer-based assays chemical sensor field effect capacitive EIS sensor pH sensor enzyme biosensor label-free detection charged molecules DNA biosensor protein detection forensics biometrics cybersecurity fingerprints blood cipher non-invasive biosensors human physiological fluids tears saliva urine |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557118203321 |
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Katz Evgeny
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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BODIPYs and Their Derivatives: The Past, Present and Future
| BODIPYs and Their Derivatives: The Past, Present and Future |
| Autore | Lu Hua |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (131 p.) |
| Soggetto topico | Science: general issues |
| Soggetto non controllato |
BODIPY
dyes/pigments spectroscopic properties synthesis borate complexes |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | BODIPYs and Their Derivatives |
| Record Nr. | UNINA-9910557316403321 |
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Lu Hua
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Carborane: Dedicated to the Work of Professor Alan Welch
| Carborane: Dedicated to the Work of Professor Alan Welch |
| Autore | Stogniy Marina Yu |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (114 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
carboranes
DFT reaction pathways boron chemistry o-carborane sulfa-Michael addition reaction cysteine boron neutron capture therapy o-carborane decapitation labeled compound 1,1'-bis(o-carborane) deboronation metalation bis(nickelation) diastereoisomers stereospecific boron clusters liquid crystals fluorescence cholesterol nido-carborane nitrilium derivatives nickel(II) half-sandwich complexes synthesis structure Lewis acid carborane carbonium ylide tetrel bond quantum chemistry electron density ELF iodo derivatives dihalogen bond X-ray structure quantum chemical calculations iron bis(1,2-dicarbollide) chromium bis(1,2-dicarbollide) tetramethyltetrathiafulvalene tetramethyltetraselenafulvalene radical-cation salts crystal and molecular structure electric conductivity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Carborane |
| Record Nr. | UNINA-9910566473603321 |
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Stogniy Marina Yu
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chemical Biology of Sterols, Triterpenoids and Other Natural Products: A Themed Issue in Honor of Professor W. David Nes on the Occasion of His 65th Birthday
| Chemical Biology of Sterols, Triterpenoids and Other Natural Products: A Themed Issue in Honor of Professor W. David Nes on the Occasion of His 65th Birthday |
| Autore | Guo De-an |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (256 p.) |
| Soggetto non controllato |
high-fat high-carbohydrate diet
toxicity oxysterol squalene cyclase sterol content sterolomics Polystichum Smith-Lemli-Opitz syndrome antifungals alkaloid cycloartenol synthase degeneration phytosterol Rhizopus arrhizus fibroblasts pod-blast fern cholesterol cytotoxic activity N-methylpiperidine. reductive deamination genetic disease isoprenoid steroid atherosclerosis granatane antioxidant wound healing development enzyme-assisted derivatization maturity terpene keratinocytes C4-demethylation complex (C4DMC) ?-sitosterol mesocarp sterol biosynthesis mechanism-based inactivators Mucorales gas chromatography-mass spectrometry (GC-MS) Girard reagent ROS sterol pattern N-methylcadaverine ?-tocopherol electrospray ionization-mass spectrometry human African trypanosomiasis HUVECs lipidomics campesterol triterpene oxyphytosterol leishmania Chagas disease LOX-1 sterol C24-methyltransferase antifungal effectivity ergosterol biosynthesis hormone glucose homeostasis retina solanaceae cholestanoic acid algal sterols cell migration withanolides insulin resistance Zingiber officinale posaconazole synthesis pre-diabetes pharmacognosy sterol 4-methylsterol oleanolic acid antiparasitic drugs lupeol oilseed aurelianolides divalent metal co-factor ligation bile alcohol phytosterols azoles infectious disease gingerols UV-radiation oil bodies ZnO sterol 14?-demethylase stigmasterol |
| ISBN | 3-03897-417-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Chemical Biology of Sterols, Triterpenoids and Other Natural Products |
| Record Nr. | UNINA-9910346835903321 |
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Guo De-an
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Contemporary natural philosophy and philosophies . Part 1 / / special issue editors, Prof. Dr. Gordana Dodig-Crnkovic and Prof. Dr. Marcin J. Schroeder
| Contemporary natural philosophy and philosophies . Part 1 / / special issue editors, Prof. Dr. Gordana Dodig-Crnkovic and Prof. Dr. Marcin J. Schroeder |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (350 p.) |
| Disciplina | 501 |
| Soggetto topico |
Science - Philosophy
Philosophy of nature |
| Soggetto non controllato |
pessimistic induction
qualitative ontology dissipative structures physicalism agent-based reasoning thermodynamics the logic of nature reverse mathematics theoretical unity state-space approach common good naturalization of logic monad metaphysics reflexive psychology knowledge neurodynamics consciousness third-way reasoning induction and discovery of laws mind-matter relations exoplanet Second Law of thermodynamics unitarity philosophical foundations in the name of nature big crunch epistemology eco-cognitive model active imagination aesthetics in science science second-person description subsumptive hierarchy 1st-person and 3rd-person perspectives discursive space space flight complexity cybernetics cosmology matter realism eco-cognitive openness hylomorphism measurement fallacies induction vacuum physics mental representation embodiment problem of induction contradiction internalism Jungian psychology synthesis exceptional experiences mind relational biology symmetry breaking emergence phenomenological psychology Aristotle's four causes humanistic management real computing A.N. Whitehead final cause naturalism induction and concept formation temporality dispositions dark energy heterogeneity Naturphilosophie computation causality memory evolutive system natural philosophy quantum computing philosophy of information self information analytical psychology logic indeterminacy scientific method dialectics computability language ethics perception philosophy of nature agonism errors of reasoning everyday lifeworld emptiness awareness unity of knowledge digitization fitness depth psychology info-computational model creativity ontology philosophy as a way of life development void big freeze signal transduction abduction retrocausality dual-aspect monism quantum information theoretical biology acategoriality epistemic norms evolutionary psychology apophasis differentiation memory centripetality mathematics Leibniz Ivor Leclerc spatial representation subjective experience intentionality evidence and justification internal quantum state scientific progress holographic encoding information-theory qualia anticipation naturalization F.W.J. Schelling L. Smolin R.M. Unger Aristotle dual aspects process theory of everything philosophy of science cognition compositional hierarchy autocatalysis discourse emergentist reductionism form regulation contingency endogenous selection category theory |
| ISBN | 3-03897-823-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346684603321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cyclodextrin Chemistry and Toxicology
| Cyclodextrin Chemistry and Toxicology |
| Autore | Isidori Marina |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (248 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
cyclodextrin
sulfamethazine zwitterion host-guest complex thermodynamics nanosponges β-cyclodextrin glutathione cancer multicellular spheroids inclusion complexes solubilization nanosponge nanocarriers pharmaceutical applications molecular recognition phenomena molecular dynamics simulations drug delivery drug concentration dyeing textile finishing textile wastewater cyclodextrins HPβCD budesonide inflammation ROS Akt HDAC cholesterol medical imaging contrast agents α-cyclodextrin γ-cyclodextrin MRI PET CT SPECT PAI Cinnamomum osmophloeum linalool microencapsulation cyclodextrin inclusion solution-phase solid state antiretroviral 3-hydroxyflavone (3HF) γ-cyclodextrin (γ-CD) excited-state proton transfer (ESPT) molecular dynamics (MD) density functional theory (DFT) cyclodextrin polymers synthesis separation science materials science biomedicine retinal explant cytotoxicity uptake risperidone inclusion complex randomly methylated β-cyclodextrin compatibility studies excipients solubility stability aggregation doxorubicin nanoparticles alveograph wheat dough bread staling |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585942703321 |
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Isidori Marina
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Design of Micro- and Nanoparticles: Self-Assembly and Application
| Design of Micro- and Nanoparticles: Self-Assembly and Application |
| Autore | Stoikov Ivan |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (290 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
electropolymerization
poly(Azure B) poly(proflavine) DNA sensor doxorubicin determination electrochemical impedance spectroscopy calix[4]arene NHC complex Suzuki-Miyaura coupling DPPC vesicles heparin/protamine particles hepatocyte intravenous injection lacZ protein nanoparticles protein delivery self-assembling antiviral agent nanoparticle coronavirus viral mechanism of entry antiviral mechanism therapeutic approaches SARS-CoV-2 COVID-19 polyol synthesis rhodium nanoparticles surfactants role of additives morphology control toxicity bio-imaging X-ray fluorescence contrast agent XFCT nanomaterials 2D nanostructures thiacalix[4]arene terpenoids geraniol X-ray crystal analysis 2D monomolecular-layer nanosheets polymorphism silica polystyrene maghemite supraparticles patchy particles seeded-growth emulsion polymerization solvent-induced self-assembly pillar[5]arene tetrazole drug delivery systems fluorescein ceria nanorods nanosheets nanozyme biomolecule template catalysis anti-oxidant oxygen radicals lithium iron phosphate hydrothermal synthesis heating rate morphology crystallinity and purity polyelectrolyte multilayers encapsulation calcium carbonate drug delivery shrinkage layered oxides perovskites bismuth titanates exfoliation coating silver nanoparticles AgNPs synthesis separation purification |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Design of Micro- and Nanoparticles |
| Record Nr. | UNINA-9910585938303321 |
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Stoikov Ivan
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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