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Precision Medicine in Solid Tumors
| Precision Medicine in Solid Tumors |
| Autore | Dey Nandini |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (304 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
pediatric tumors
tumor mutational burden TMB whole-exome sequencing gene panel sequencing immune checkpoint inhibitors glioblastoma prognosis overall survival extent of resection random forest Decision tree personalized precision oncology circulating free DNA liquid biopsy epidermal growth factor receptor tyrosine kinase inhibitor osimertinib comprehensive genomic profiling molecular genotyping intratumor heterogeneity multiple biopsies tumor evolution clonality classification strategic therapeutic intervention thymoma driver mutation sequencing molecular barcoding EGFR mutation EGFR-TKI cfDNA NGS digital enrichment next-generation sequencing solid cancer universal health-care system precision medicine presumed germline findings clinical guideline non-small cell lung cancer outcome adjuvant chemotherapy anaplastic lymphoma receptor tyrosine kinase HNSCC ctDNA tDNA DDR genes PARP inhibitors new drug development next-generation sequencing (NGS) open data regulatory reform tumor profiling test triple-negative breast cancer (TNBC) breast cancer targeted therapy TNBC subtypes immunotherapy cancer screening smoking electronic records PD-L1 cancer-associated fibroblasts resistance chemotherapy CTC immunocytochemistry parallel double-detection laboratory-friendly |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595078103321 |
Dey Nandini
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Advances in the Understanding of Molecular Mechanisms of Resistance in Noctuid Pests
| Recent Advances in the Understanding of Molecular Mechanisms of Resistance in Noctuid Pests |
| Autore | Le Goff Gaelle |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (142 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
fall armyworm
insecticide resistance target-site mutations Bt resistance corn strain rice strain resistance management Indonesia Kenya 1'S-1'-Acetoxychavicol acetate Alpinia galanga Spodoptera frugiperda Sf9 cells botanical pesticide Mythimna loreyi rice armyworm invasive pest LAMP diagnostic PCR Helicoverpa armigera transposable elements insertions sites insecticide resistance genes insect rearing dynamic energy budget (DEB) theory development temperature variability Bacillus thuringiensis Cry protein ATP-Binding Cassette ABC Transporter ATP switch model pore-forming toxin resistance genetics Noctuidae Helicoverpa Spodoptera Heliothis Chloridea Trichoplusia ABCC2 biological invasion Cytochrome P450 Fall armyworm cytochromes P450 carboxyl/cholinesterases glutathione S-transferases ATP-binding cassette transporters soybean looper reference genes Cry1F genotyping targeted sequencing resistance screen |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557478203321 |
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Le Goff Gaelle
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Developments on Protein–Ligand Interactions : From Structure, Function to Applications
| Recent Developments on Protein–Ligand Interactions : From Structure, Function to Applications |
| Autore | de Brevern Alexandre G |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (282 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
pimaricin thioesterase
protein-substrate interaction macrocyclization molecular dynamics (MD) simulation pre-reaction state folate folate receptor peptide conjugation click reaction biolayer interferometry acetylcholinesterase resistance organophosphorus pesticides molecular modeling lepidopterous insects conserved patterns similarity 3D-patterns epigenetics protein-RNA interaction RRM domain inhibitor NMR fragment-based screening TDP-43 galectin-1 gulopyranosides fluorescence polarization benzamide selective phospholipase C gamma 1 SLP76 virtual screening pharmacophore mapping molecular docking molecular dynamics caspase inhibition protein-ligand binding free energy Monte Carlo sampling docking and scoring molecular conformational sampling procollagen C-proteinase enhancer-1 glycosaminoglycans computational analysis of protein-glycosaminoglycan interactions calcium ions fragment-based docking protein–ligand analysis drug discovery and design structure–activity relationships bioremediation High Energy Molecules HMX protein design nitroreductase flavoprotein substrate specificity pharmacophore secretoglobin odorant-binding protein chemical communication pheromone N-phenyl-1-naphthylamine in silico docking protein–ligand interactions 2D interaction maps ligand-binding assays protein-ligand complexes dataset clustering structural alignment refinement PD-1/PD-L1 immune checkpoint inhibitors biphenyl-conjugated bromotyrosine amino acid conjugation amino-X in silico simulation IC50 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Recent Developments on Protein–Ligand Interactions
Recent Developments on ProteinâLigand Interactions |
| Record Nr. | UNINA-9910566462703321 |
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de Brevern Alexandre G
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Religion, Power, and Resistance : New Ideas for a Divided World
| Religion, Power, and Resistance : New Ideas for a Divided World |
| Autore | Halafoff Anna |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (196 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
sociology of religion
post-colonial reflexivity epistemology race religion violence South Africa decoloniality Chinese religion secularization Xunzi Durkheim identity African Pentecostalism integration transnationalism diaspora religious diversity religions law media education religious strength sex gender Canada religion and migration intersectionality popular religions multiple modernities lived religion power resistance social theory holistic spirituality Ghana's New Churches ideology dominant ideology alternative ideology political power social constructionism Islamism Islam Shi'ism spiritualism rituals Iran non-religion atheism persecution policy diversity young people spirituality complexity hybridity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Religion, Power, and Resistance |
| Record Nr. | UNINA-9910557551203321 |
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Halafoff Anna
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Resistance to Salinity and Water Scarcity in Higher Plants. Insights From Extremophiles and Stress-Adapted Plants: Tools, Discoveries and Future Prospects
| Resistance to Salinity and Water Scarcity in Higher Plants. Insights From Extremophiles and Stress-Adapted Plants: Tools, Discoveries and Future Prospects |
| Autore | Grene Ruth |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (117 p.) |
| Soggetto topico |
Science: general issues
Botany & plant sciences |
| Soggetto non controllato |
salinity
water stress resistance adaptation extremophiles |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Resistance to Salinity and Water Scarcity in Higher Plants. Insights From Extremophiles and Stress-Adapted Plants |
| Record Nr. | UNINA-9910557484303321 |
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Grene Ruth
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The revolution before the revolution : late authoritarianism and student protest in Portugal / / Guya Accornero
| The revolution before the revolution : late authoritarianism and student protest in Portugal / / Guya Accornero |
| Autore | Accornero Guya |
| Pubbl/distr/stampa | New York ; ; Oxford, [England] : , : Berghahn, , [2016] |
| Descrizione fisica | 1 online resource (186 p.) |
| Disciplina | 946.9043 |
| Collana | Protest, Culture and Society |
| Soggetto topico |
Student movements - Portugal - 20th century
Student protestors - Portugal - 20th century |
| Soggetto non controllato |
1974
authoritarian carnation revolution colonialism communist party democracy democratization engaging estado novo regime european history fights governing government history military coup modern history page turner police studies political popular movements portugal portuguese democratization portuguese history protest realistic resistance revolt revolution revolutionary social movement societal convulsions sociology tyranny warfare warriors |
| ISBN | 1-78533-115-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Title Page; Table of Contents; List of Figures; Acknowledgments; List of Abbreviations; Introduction; Chapter 1. Two Decades That Shook the World: 1956-1974; Chapter 2. The First Protest Cycle: 1956-1965; Chapter 3. 'The Marcelo's Spring' and the Opening of a Second Protest Cycle; Chapter 4. Protest Cycle or Permanent Conflict?; Chapter 5. The Demise of the New State; Conclusions. Social Movements and Authoritarianism; Bibliography; Index |
| Record Nr. | UNINA-9910798356503321 |
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Accornero Guya
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| New York ; ; Oxford, [England] : , : Berghahn, , [2016] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The revolution before the revolution : late authoritarianism and student protest in Portugal / / Guya Accornero
| The revolution before the revolution : late authoritarianism and student protest in Portugal / / Guya Accornero |
| Autore | Accornero Guya |
| Pubbl/distr/stampa | New York ; ; Oxford, [England] : , : Berghahn, , [2016] |
| Descrizione fisica | 1 online resource (186 p.) |
| Disciplina | 946.9043 |
| Collana | Protest, Culture and Society |
| Soggetto topico |
Student movements - Portugal - 20th century
Student protestors - Portugal - 20th century |
| Soggetto non controllato |
1974
authoritarian carnation revolution colonialism communist party democracy democratization engaging estado novo regime european history fights governing government history military coup modern history page turner police studies political popular movements portugal portuguese democratization portuguese history protest realistic resistance revolt revolution revolutionary social movement societal convulsions sociology tyranny warfare warriors |
| ISBN | 1-78533-115-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Title Page; Table of Contents; List of Figures; Acknowledgments; List of Abbreviations; Introduction; Chapter 1. Two Decades That Shook the World: 1956-1974; Chapter 2. The First Protest Cycle: 1956-1965; Chapter 3. 'The Marcelo's Spring' and the Opening of a Second Protest Cycle; Chapter 4. Protest Cycle or Permanent Conflict?; Chapter 5. The Demise of the New State; Conclusions. Social Movements and Authoritarianism; Bibliography; Index |
| Record Nr. | UNINA-9910819013103321 |
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Accornero Guya
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| New York ; ; Oxford, [England] : , : Berghahn, , [2016] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Natural Bioactive Compounds in the Rise and Fall of Cancers : Volume 2
| Role of Natural Bioactive Compounds in the Rise and Fall of Cancers : Volume 2 |
| Autore | Luparello Claudio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (318 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
berberine
signaling pathways oncogenic cascades TRAIL microRNAs cancer therapy colon cancer cells ethanol Nrf2 HO-1 ER stress autophagy MMPs formononetin cancer preclinical models cell signaling angiogenesis nobiletin colorectal cancer chemoprevention bioactivities experimental therapeutics HDAC multiple myeloma oleacein breast cancer persistent organic pollutants breast cancer risk breast cancer prognostic systematic review carrageenan invasion metastasis RacGAP1 radiotherapy marine sponge natural product anticancer drug oral cancer inhibition phytochemicals small organic agents Piper eriopodon, alkenylphenols human cancer cells cell death apoptosis caspase-independent cell death XIAP antagonists XIAP-BIR3 domain Calocedrus formosana lung cancer yatein cell-cycle arrest xenograft isorhamnetin G2/M arrest ROS AMPK pancreatic cancer epigallocatechin-3-gallate (EGCG) gemcitabine glycolysis phosphofructokinase natural polyphenols anticancer activities molecular mechanisms Streptomyces mangrove anti-proliferative colon cancer epithelial mesenchymal transition inflammation malignant cancer natural anti-inflammatory compounds pro-resolving lipids anticancer drugs flavonoids natural compounds Xenopus laevis AOM/DSS model melanoma cells nicotine α9-nAChR PD-L1 STAT3 gigantol AKT JAK/STAT cancer stem cell tumor maintenance tumor density proteomics honokiol anticancer mechanism signalling pathway uterine sarcoma fucoidan isobolography colchicine alkaloid mesoporous silica nanoparticles targeted delivery system PD-1 immune checkpoint inhibitor and cancer immunotherapy glucose transport drugs innate immunity β-glucans nutrition immunotherapy estrogen estrogen receptor alpha polyphenols daidzein daidzein metabolites paclitaxel breast cancer cells obesity renin-angiotensin system eicosapentaenoic acid adipocyte inflammation olive leaf extract oleuropein Seahorse analysis cancer metabolism glycolytic markers Malva pseudolavatera Webb & Berthel acute myeloid leukemia reactive oxygen species brain cancer gliomas schwannomas malignant tumors of the peripheral nerve sheath (MPNST) neurofibromas bioavailability nanoparticle-based delivery systems natural bioactive compound gallic acid EGFR signaling p53 EGCG non-coding RNAs anti-cancer drug NSCLC EGFR TKI FASN inhibitors resistance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Role of Natural Bioactive Compounds in the Rise and Fall of Cancers |
| Record Nr. | UNINA-9910557476303321 |
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Luparello Claudio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Spumaretroviruses
| Spumaretroviruses |
| Autore | Khan Arifa |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (352 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
spumavirus
feline illness proviral load neglected virus bovine foamy virus infectious clone particle release cell-free transmission foamy virus spumaretrovirus cross-species virus transmission zoonosis restriction factors immune responses FV vectors virus replication latent infection feline foamy virus epidemiology retrovirus Spumaretrovirus mountain lion Puma concolor ELISA protease reverse transcriptase RNase H reverse transcription antiviral drugs resistance simian foamy virus gibbon lesser apes co-evolution complete viral genome equine foamy virus isolation Japan sero-epidemiology reptile foamy virus endogenous foamy virus endogenous retrovirus ancient retroviruses co-speciation foamy virus-host interactions viral tropism infection kidney cats chronic kidney disease chronic renal disease integrase integration co-infections NHP pathogenesis zoonoses viral prevalence Neotropical primates free-living primates Brazil new world primates simian retrovirus BFV spuma virus model system animal model animal experiment miRNA function gene expression antiviral host restriction gene therapy in-vivo gene therapy hematopoietic stem and progenitor cells foamy virus vector pre-clinical canine model SCID-X1 innate sensing cGAS STING foamy viruses wild ruminants European bison red deer roe deer fallow deer seroreactivity inter-species transmission HSC gene marking FV gene transfer to HSCs gene therapy alternatives serotype high-throughput sequencing replication kinetics cytopathic effect reverse transcriptase activity miRNA expression virus-host-interaction miRNA target gene identification innate immunity ANKRD17 Bif1 (SH3GLB1) replication in vitro |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557409103321 |
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Khan Arifa
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Sustainable Construction Engineering and Management
| Sustainable Construction Engineering and Management |
| Autore | Zavadskas Edmundas Kazimieras |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (680 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
building information modeling
project owner attitude behavior technology acceptance model BIM information model bridge maintenance management system Public–private partnership (PPP) risk identification risk relationship triangular fuzzy number ISM MICMAC data collection system worker’s smartphone concrete temperature monitoring high-rise building construction sustainable roles LEED contractors Vietnam bridge deterioration prediction model semi-Markov process Weibull-distribution condition rating sustainable construction project management (SCPM) sustainable performance evaluation set pair analysis informatization greenization Guangzhou metro China time management delay management mitigation strategy owner perspective contractor perspective power construction project Tanzania knowledge transfer safety behavior safety management construction site structural equation modeling (SEM) building information modeling (BIM) building performance assessment (BPA) key performance indicators (KPIs) facility management (FM) operation and maintenance (O& M) operating room (OR) defects liability period risk matrix residential buildings loss distribution approach decision tree analytic hierarchy process dynamic programming sustainable investment project participants’ behaviour roof installation projects modular construction rework integrated design process dependency structure matrix (DSM) process optimization sustainability green building delay sources risk management random forest-genetic algorithm computer aid construction project bridge construction risk analysis loss assessment model third-party damage insurance sensitivity analysis uncertainty modelling load action resistance limit states stochastic simulation failure probability structural reliability correlations linguistic action indicators last planner system linguistic action perspective resource-dependent activity relationship scheduling scheduling software Microsoft Excel Visual Basic for Applications (MS Excel VBA) rework causes SWARA method time project success building projects sustainable construction value management exploratory factor analysis construction management green building materials (GBMs) building industry Sustainable Development Goals (SDGs) construction industry MCDM COPRAS method real case study enterprise competitiveness organizational flexibility organizational innovation modernization of construction industry structural equation modeling natural language processing construction data management machine learning thermal insulation multi criteria analysis SALSA buildings Renovation Wave sustainable highway construction sustainability indicators triangular intuitionistic fuzzy multi-criteria decision-making entropy measure risk attitudes organizational learning fly ash geopolymer environment sustainable construction public private partnership critical success factors fuzzy synthetic evaluation project governance maintenance, repair, and rehabilitation (MR& R) inspection optimization infrastructure decision making life cycle assessment materials greenhouse digital transformation digital technology strategy change management project assessment sustainability criteria construction projects decision robustness risk process project management IDEF0 risk system implementation design smart technologies decision-making methods |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557421003321 |
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Zavadskas Edmundas Kazimieras
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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