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Isolation and Identification of Bioactive Secondary Metabolites
| Isolation and Identification of Bioactive Secondary Metabolites |
| Autore | Seca Ana Maria Loureiro da |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (272 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
coumarins
Lycium metabolomic HPLC-MS orbitrap secondary metabolites endemic plants olive leaves supercritical fluid extraction antioxidants hyperuricemia plant-based functional food xanthine oxidase adenosine deaminase uric acid transporter bioactive compound Piper pseudoarboreum bioassay-guided fractionation leishmanicidal activity alkamides (E)-piplartine Wedelia chinensis organic farming phytotoxic substances vanillic acid gallic acid Origanum subspecies morphological traits glandular trichomes essential oil composition rosmarinic acid sensory evaluation colored potato tubers total phenols anthocyanins saccharides nutrition microelements plants fungi food supplements cardiovascular diseases neurodegenerative diseases Alzheimer's disease metabolic syndrome apocarotenoid caffeic acid derivative flavonoid Lactuca sativa lignan megastigmane sesquiterpene lactone 1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid black chokeberry anthocyanin simulated moving bed antioxidant activity neuroprotection Artemisia clinical trials health effects adverse effects anticancer antiparasitic artemisinin santonin achillin tehranolide Aglaomorpha quercifolia GC-MS profile rhizome leaves n-hexane extract fatty acids terpenoids linolenic acid hop-16-ene cardiac glycosides secondary plant metabolites natural product isolation hyrcanoside deglucohyrcanoside ouabain cymarin digitoxin anticancer activity Na+/K+-ATPase inhibitors corn salad leafy vegetables phytochemicals liquid chromatography mass spectrometry celastrol Celastraceae antimicrobial activity mechanism of action Bacillus subtilis |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576883103321 |
Seca Ana Maria Loureiro da
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Medicinal Plants for Cardiovascular and Neurodegenerative Aging-related Diseases: From Bench to Bedside
| Medicinal Plants for Cardiovascular and Neurodegenerative Aging-related Diseases: From Bench to Bedside |
| Autore | Liu Yue |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (294 p.) |
| Soggetto topico |
Science: general issues
Pharmacology |
| Soggetto non controllato |
medicinal plants
aging age-related diseases cardiovascular disease neurodegenerative diseases |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Medicinal Plants for Cardiovascular and Neurodegenerative Aging-related Diseases |
| Record Nr. | UNINA-9910557386003321 |
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Liu Yue
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondrial Dysfunction and Neurodegeneration
| Mitochondrial Dysfunction and Neurodegeneration |
| Autore | Tapias Victor |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (209 p.) |
| Soggetto topico |
Science: general issues
Neurosciences |
| Soggetto non controllato |
mitochondrial dysfunction
quality control neurodegenerative diseases Parkinson's disease Alzheimer's disease |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557387303321 |
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Tapias Victor
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nanobody
| Nanobody |
| Autore | Rothbauer Ulrich |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Bacillus anthracis
immunoassay single-domain antibody genetic fusion Beta galactosidase P-type ATPase nanobody llama Zinc-transport Zinc-transporting P-ATPase ZntA TNF fluorescent nanobodies sensor anti-cytokine therapy autoimmune disease Western equine encephalitis virus MagPlex toxin antibody camelid vaccine biodefense hydrogen exchange-mass spectrometry virus formatting Fc-domain half-life ischemia stroke MCAO single domain antibodies phage display intrabody intracellular antibody GTPase RHO BRET RAS chromobodies live-cell imaging compound screening cellular models single-domain antibody fragments molecular imaging molecular therapy nuclear imaging targeted fluorescence imaging intraoperative imaging Nanobody Single Domain Antibody Cancer Immunotherapy Imaging influenza influenza B virus hemagglutinin single domain antibody NanobodyTM yeast display epitope mapping GFP C. elegans development drosophila zebrafish targeted photodynamic therapy hepatocyte growth factor receptor HGFR c-Met Met VHH photosensitizer single-domain antibodies neurodegenerative diseases brain imaging blood-brain barrier delivery Aids HIV Llama Antibodies bi-specific VHH pepscan competition studies co-crystallisation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557147503321 |
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Rothbauer Ulrich
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nanomedicine Formulations Based on PLGA Nanoparticles for Diagnosis, Monitoring and Treatment of Disease: From Bench to Bedside
| Nanomedicine Formulations Based on PLGA Nanoparticles for Diagnosis, Monitoring and Treatment of Disease: From Bench to Bedside |
| Autore | Tagit Oya |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (296 p.) |
| Soggetto topico |
Technology: general issues
History of engineering & technology Materials science |
| Soggetto non controllato |
poly(lactic-co-glycolic acid) (PLGA)
blood–brain barrier (BBB) current Good Manufacturing Practice (cGMP) Food and Drug Administration (FDA) nanotechnology PLGA nanoparticles neurodegenerative diseases drug delivery central nervous system neuroprotective drugs fluorescent labeling DiI coumarin 6 rhodamine 123 Cy5.5 quantum yield brightness stability of fluorescent label confocal microscopy intracellular internalization in vivo neuroimaging double-emulsion method dry powder inhalation antigen release porous PLGA particles microfluidics methotrexate chitosan PLA/PLGA sustained release micro-implant animal model minimally invasive drug delivery system nanoparticles poly (lactic-co-glycolic acid) (PLGA) microfluidic pharmacokinetics (PK) and biodistribution atorvastatin calcium poly(lactide-co-glycolide) polymeric nanoparticles carrageenan induced inflammation anti-inflammatory radiolabeled nanoparticles nuclear medicine photothermal therapy phthalocyanine SKOVip-kat Katushka TurboFP635 JO-4 PLGA orthotopic tumors 3D culture spheroids poly(lactic-co-glycolic acid) nanomedicine scale-up manufacturing clinical translation inline sonication tangential flow filtration lyophilization downstream processing H. pylori design of experiments poly(lactic-co-glycolic) acid size cancer chemoimmunotherapy immunogenic cell death immune checkpoint blockade PNA5 glycopeptide mas receptor angiotensin PLGA diblock copolymer ester and acid-end capped double emulsion solvent evaporation biocompatible biodegradable cardiovascular nanoparticle solid-state characterization in vitro drug release kinetics modeling PEGylation amine emulsion polyvinyl alcohol (PVA) Pluronic triblock copolymer trehalose sucrose Indomethacin solvents stabilizers morphology particle-size encapsulation drug release cytotoxicity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Nanomedicine Formulations Based on PLGA Nanoparticles for Diagnosis, Monitoring and Treatment of Disease |
| Record Nr. | UNINA-9910580215803321 |
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Tagit Oya
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Natural Products and Neuroprotection
| Natural Products and Neuroprotection |
| Autore | Angeloni Cristina |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (338 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Vitamin D
Multiple Sclerosis symptom neurodegeneration oxidative injury Parkinson's disease terpenes, rotenone thymol Alzheimer's disease Centella asiatica hippocampus protein poshophatase 2 glycogen synthase kinase 3 B-cell lymphoma 2 neuroprotection nutraceuticals bioavailability stress response neurodegenerative disease bioactive compound natural extract β-amyloid peptide tau protein clinical trial human studies animal studies in vitro studies curcumin free radicals heme oxygenase safety profile type 2 diabetes inflammation vascular damage learning memory natural compound oxidative stress cognitive dysfunction cell death synapse loss protein aggregation neuroinflammation algae seaweeds neurodegenerative diseases auraptene dopamine neuron antioxidant mitochondria Chionanthus retusus flavonoid flower HO-1 NO Lippia citriodora VEE Vs relaxation depression cyclic AMP calcium blood-brain barrier catechin cognition epigallocatechin gallate green tea microbiota 5-(3,5-dihydroxyphenyl)-γ-valerolactone ascaroside pheromone C. elegans dauer neuronal signaling sexual behavior survival signals proteostasis chaperones autophagy ubiquitin-proteasome unfolded protein response natural compounds natural products ethics patients' autonomy beneficence nonmaleficence medical liability Parkinson's disease (PD) mitochondrial dysfunction dynamics hormesis ubiquitin‒proteasome system (UPS) mitophagy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557705603321 |
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Angeloni Cristina
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neuroinflammation and its Resolution: From Molecular Mechanisms to Therapeutic Perspectives
| Neuroinflammation and its Resolution: From Molecular Mechanisms to Therapeutic Perspectives |
| Autore | Zusso Morena |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (282 p.) |
| Soggetto topico |
Science: general issues
Pharmacology |
| Soggetto non controllato |
neuroinflammation
neurodegenerative diseases microglia cytokines therapeutic targets |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Neuroinflammation and its Resolution |
| Record Nr. | UNINA-9910557492503321 |
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Zusso Morena
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neurotransmitter-Related Molecular Modeling Studies
| Neurotransmitter-Related Molecular Modeling Studies |
| Autore | Nowaczyk Alicja |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (188 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
white matter hyperintensities
dysautonomia genetic polymorphisms dementia levodopa renin-angiotensin system orthostatic hypotension reserpine-induced fibromyalgia model vortioxetine ropinirole serotonin and dopamine in fibromyalgia mouse dopamine acetylcholine glutamate BDNF serotonin neurotransmitters statins neurodegenerative diseases stroke depression androgenetic alopecia 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors mixed dyslipidemia risk factors halogenated pyrazolines monoamine oxidase inhibitors kinetics reversibility molecular dynamics guanylate cyclase (GC) chronic heart failure (CHF) pulmonary arterial hypertension (PAH) tiagabine cardiac voltage-gated ion channels molecular modeling ECG study SGLT2i sodium-glucose cotransporter 2 inhibitors neuroprotection atheroprotection mTOR type 2 diabetes mellitus cognitive impairment inflammation oxidative stress antibiotics neurotoxicity adverse drug reaction neurotransmission 5-HT receptors gastrointestinal tract |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580213903321 |
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Nowaczyk Alicja
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Non-Motor Symptoms in Primary Motor Neurological Disorders: from Molecular Pathways to Clinical and Therapeutic Implications
| Non-Motor Symptoms in Primary Motor Neurological Disorders: from Molecular Pathways to Clinical and Therapeutic Implications |
| Autore | Trojsi Francesca |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (130 p.) |
| Soggetto topico |
Science: general issues
Neurosciences |
| Soggetto non controllato |
neurodegenerative diseases
movement disorders motor neuron disease non-motor symptoms C9orf72 hexanucleotide repeat expansion neuropsychiatric disorders sleep disorders levodopa response |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Non-Motor Symptoms in Primary Motor Neurological Disorders |
| Record Nr. | UNINA-9910557205803321 |
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Trojsi Francesca
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nutrition and Central Nervous System
| Nutrition and Central Nervous System |
| Autore | Mohajeri M. Hasan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (182 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
dipeptide
dopamine hippocampus memory monoamine oxidase B milk hypothalamus nucleus accumbens reward appetite palatability major depressive disorder Chinese herbal formula corticosterone BDNF oxidative stress probiotics microbiota beneficial bacteria psychobiotics human health neurodegenerative diseases neuroinflammation apoptosis synaptic dysfunction IRS1 serine phosphorylation diabetes aging Alzheimer’s disease memory decline Aβ AMPK energy depletion S-equol 17β-estradiol estrogen receptor alpha cell cycle β-Amyloid microbiome microbiota-gut-brain axis ADHD attention-deficit-hyperactive-disorder Angelica gigas mild cognitive impairment traumatic brain injury chronic mild stress children cingulum development dietary sugar fructose |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557553503321 |
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Mohajeri M. Hasan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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