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Regulatory RNAs in the Nervous System, 2nd Edition
| Regulatory RNAs in the Nervous System, 2nd Edition |
| Autore | Tommaso Pizzorusso |
| Pubbl/distr/stampa | Frontiers Media SA, 2018 |
| Descrizione fisica | 1 electronic resource (346 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
neurodevelopment
neurodevelopmental disorder transcriptomics neurodegeneration aging brain plasticity |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346737703321 |
Tommaso Pizzorusso
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| Frontiers Media SA, 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Sphingolipids : From Pathology to Therapeutic Perspectives - A Themed Honorary Issue to Prof. Lina Obeid
| Sphingolipids : From Pathology to Therapeutic Perspectives - A Themed Honorary Issue to Prof. Lina Obeid |
| Autore | van Echten-Deckert Gerhild |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (292 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
S1P receptor
inflammation S1P transporter spinster homolog 2 barrier dysfunction anxiety depression sphingolipids sphingomyelinase ceramidase Smpd1 acid sphingomyelinase forebrain depressive-like behavior anxiety-like behavior ceramide ceramides ceramidases neurodegenerative diseases infectious diseases sphingosine 1-phoshate sphingosine 1-phosphate receptor S1P1-5 sphingosine 1-phosphate metabolism sphingosine 1-phosphate antagonistst/inhibitors sphingosine 1-phosphate signaling stroke multiple sclerosis neurodegeneration fingolimod Sphingosine-1-phosphate obesity type 2 diabetes insulin resistance pancreatic β cell fate hypothalamus sphingosine-1-phosphate ischemia/reperfusion cardioprotection vasoconstriction coronary flow myocardial function myocardial infarct albumin type 1 diabetes beta-cells islets insulin cytokines S1P animal models cystic fibrosis autophagy myriocin Aspergillus fumigatus CLN3 disease Cln3Δex7/8 mice flupirtine allyl carbamate derivative apoptosis cancer gangliosides immunotherapy metastasis phenotype switching sphingosine 1-phosphate Sphingosine 1-phosphate (S1P) S1P-lyase (SGPL1) tau calcium histone acetylation hippocampus cortex astrocytes neurons sphingosine kinase G-protein-coupled receptors Gαq/11 sphingosine kinase 1 SK1 microRNA transcription factor hypoxia long non-coding RNA |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Sphingolipids |
| Record Nr. | UNINA-9910557545203321 |
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van Echten-Deckert Gerhild
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Systems Analytics and Integration of Big Omics Data
| Systems Analytics and Integration of Big Omics Data |
| Autore | Hardiman Gary |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (202 p.) |
| Soggetto non controllato |
precision medicine informatics
drug sensitivity chromatin modification cell lines biocuration neurodegeneration multivariate analysis artificial intelligence epigenetics missing data sequencing clinical data class imbalance integrative analytics algorithm development for network integration deep phenotype non-omics data feature selection Gene Ontology miRNA-gene expression networks omics data plot visualization Alzheimer's disease tissue classification epidemiological data proteomic analysis genotype RNA expression indirect effect multi-omics dementia multiomics integration data integration phenomics network topology analysis challenges transcriptome enrichment analysis regulatory genomics scalability heterogeneous data systemic lupus erythematosus database microtubule-associated protein tau disease variants genomics joint modeling distance correlation annotation phenotype direct effect curse of dimensionality gene-environment interactions logic forest machine learning KEGG pathways multivariate causal mediation amyloid-beta bioinformatics pipelines support vector machine pharmacogenomics candidate genes tissue-specific expressed genes cognitive impairment causal inference |
| ISBN | 3-03928-745-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404089603321 |
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Hardiman Gary
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targets, Tracers and Translation - Novel Radiopharmaceuticals Boost Nuclear Medicine
| Targets, Tracers and Translation - Novel Radiopharmaceuticals Boost Nuclear Medicine |
| Autore | Reischl Gerald |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (214 p.) |
| Soggetto non controllato |
pretargeting
radioiodination neurodegeneration phosphoramidon GRPR molecular imaging allosteric modulator radiosynthesis separation ?-CIT PET/CT imaging technetium-99m gastrin-releasing peptide receptor metabotropic glutamate receptor subtype 5 glutamate oncogenic fusions Fusarinine C hypoxia tirapazamine (TPZ) 68Ga sentinel lymph node 99mTc-radioligand iodine-131 electrophilic radioiodination 4-dioxide (BTDO) minigastrin ceftriaxone tropomyosin receptor kinase carbonic anhydrase IX ABP688 NPY(Y1)R MMPEP radiosensitizer neprilysin-inhibition radiochemistry girentuximab benzotriazine-1 gallium-68 cholecystokinin-2 receptor tumor targeting radioimmunotherapy salivary gland uptake metabolic stability tumor hypoxia multimerization oxidizing agent neuroinflammation gastrin-releasing peptide dextran carbon-11 peptide heterodimers apparent molar activity radiometals microglia rituximab [18F]FMISO [11C]meta-hydroxyephedrine Iodo-Gen® mannose 177Lu-radiopharmaceuticals azomycin nucleosides breast cancer click chemistry small animal imaging SR 4317 benzotriazine-1-monoxide (BTMO) bombesin prostate cancer Chloramine T 99mTc-radiopharmaceuticals ketamine PSMA-617 positron emission tomography hydrazinonicotinic acid (HYNIC) renal cell carcinomas [18F]PSS232 PET endoradiotherapy |
| ISBN | 3-03921-314-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367759003321 |
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Reischl Gerald
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The CB2 Cannabinoid System: A New Strategy in Neurodegenerative Disorder and Neuroinflammation
| The CB2 Cannabinoid System: A New Strategy in Neurodegenerative Disorder and Neuroinflammation |
| Autore | Marialessandra Contino |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 electronic resource (100 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
Cannabinod system
CB2 receptor CB2R inverse AD PD neurodegeneration CB2R agonist Inflammation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | CB2 Cannabinoid System |
| Record Nr. | UNINA-9910227347103321 |
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Marialessandra Contino
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Metabolic-Inflammatory Axis in Brain Aging and Neurodegeneration
| The Metabolic-Inflammatory Axis in Brain Aging and Neurodegeneration |
| Autore | Enrique Cadenas |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 electronic resource (161 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
Brain aging
Mitochondria Energy Metabolism neurodegeneration Neuroinflammation Perimenopause redox homeostasis Alzheimer's disease diabetes |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910261145403321 |
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Enrique Cadenas
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Molecular and Cellular Basis for Parkinson's Disease
| The Molecular and Cellular Basis for Parkinson's Disease |
| Autore | Müller Thomas |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (230 p.) |
| Soggetto non controllato |
microRNAs
disease-modifying effects SH-SY5Y inpatient treatment sphingolipids neurodegeneration magnetic resonance spectroscopy MO3.13 schizophrenia epigenetics long-chain acylcarnitine molecular mimicry curli multimodal complex treatment chlorogenic acid glycerophospholipids caffeic acid lipoproteins myenteric plexus neurometabolites HOG immature oligodendrocyte autophagy oligodendrocyte hypochlorite alpha-synuclein microbiome glucocerebrosidase Lewy Body Dementia brain iron mesenchymal stem cells fatty acid ?-oxidation GABA enteric glial cell gut-brain axis microbiota REM sleep behavior disorders redox cycling magnetic resonance imaging differentiation ?-synuclein-mediated pathology Parkinson disease Gaucher’s disease metallothionein [123I]FP-CIT-SPECT dopaminergic neuron mature oligodendrocyte glycerolipids spectroscopy neuroinflammation exosomes immunotherapy DNA methylation sterol lipids nigral cells cell line cysteinyl-dopamine myelin parkinsonisms multiple sclerosis rotenone brain fatty acyls Krabbe’s disease neuroprotection DAT motor dysfunction secretome multiprofessional therapy Parkinson’s disease oxidative stress alpha-Synuclein |
| ISBN | 3-03921-549-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367753003321 |
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Müller Thomas
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Protein Alpha-Synuclein: Its Normal Role (in Neurons) and its Role in Disease
| The Protein Alpha-Synuclein: Its Normal Role (in Neurons) and its Role in Disease |
| Autore | Manfredsson Fredric P |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (151 p.) |
| Soggetto topico |
Science: general issues
Neurosciences |
| Soggetto non controllato |
alpha-synuclein function
alpha-synuclein aggregation neurodegeneration Parkinson's disease synucleinopathies |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Protein Alpha-Synuclein |
| Record Nr. | UNINA-9910557552603321 |
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Manfredsson Fredric P
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Retina in Health and Disease
| The Retina in Health and Disease |
| Autore | Ptito Maurice |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (465 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
eye
retina development vascularization hypoxia autophagy programmed cell death cellular senescence retinogenesis altricial bird species precocial bird species senescence-associated galactosidase activity diabetes mellitus retinopathy microvascular complication optical coherence tomography angiography black African-American systemic disease biomarker retinal degenerative diseases mesenchymal stem cells stem cell therapy experimental models clinical trials AMD age-related macular degeneration trichostatin A (TSA) HDAC histone deacetylase vascular endothelial growth factor (VEGF) retinal degeneration endoplasmic reticulum stress response unfolded protein response GRP78 retinal glial cell diabetic retinopathy zebrafish neurovascular unit microvascular complications and dysfunction metabolism motor protein myosin 1C photoreceptor rhodopsin outer segments visual function macroglia astrocytes Müller cells optic nerve crush retinal ganglion cells spinal cord injury signal transducer and activator of transcription 3 epidermal growth factor Drp1 apoptosis mitochondria microglia neurodegeneration multiple sclerosis retinal microglia microglia morphotype light damage functional analysis early detection remodeling lactate GPR81 HCAR1 growth cone dLGN axon 3,5-DHBA kallikrein-kinin system kinin receptors GFAP osteopontin retinal detachment diabetes antioxidants bioenergetics respiration ATP glucagon-like peptide-1 exendin-4 catalase immunohistochemistry electron microscopy Charles Bonnet syndrome EEG visual hallucination resting state high-fat diet gut microbiome gut-retina axis RNA sequencing germ-free mice complement cascade angiogenesis retinal inflammation AII amacrine cell Prox1 parvalbumin gap junction eccentricity ON/OFF asymmetry arterioles betulinic acid ischemia-reperfusion injury reactive oxygen species retinal vessels retinal fluorescence imaging amyloid cognitive decline Alzheimer's disease optic neuritis oxidative stress neuroprotection fingolimod iPSC-RPE retinal pigment epithelium immunodeficient RCS rat ultrathin parylene retinal transplantation CD4+CD25+ inflammation iPSC typical cannabinoid receptors atypical cannabinoid receptors electroretinography monkeys visual system eye inflammation lipopolysaccharide natural bioactive extracts Ac2-26 FPR receptor inflammatory mediators retinal light injury LED screen optical filter retinal protection regeneration progenitor cell hyperglycemia photoreceptors neurod Notch |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557336603321 |
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Ptito Maurice
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of Fibrinolytic System in Health and Disease
| The Role of Fibrinolytic System in Health and Disease |
| Autore | Kwaan Hau C |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (170 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
COVID-19
fibrinolysis renin-aldosterone-angiotensin-system (RAAS) plasminogen activator inhibitor 1 (PAI-1) urokinase plasminogen activator urokinase plasminogen activator receptor plasminogen activator inhibitor-1 acute lung injury and repair and pleural injury and pleural organization PAI-1 cardiovascular disease cancer inflammation fibrosis aging obstructive sleep apnoea OSA coagulation platelets brown adipose tissue obesity plasminogen activation immune response thrombin activatable fibrinolysis inhibitor TAFI proCPU proCPB proCPR carboxypeptidase uPA uPAR PA system tissue-type plasminogen activator (tPA) urokinase-type plasminogen activator (uPA) neurodegeneration thrombin shear clot retraction Factor XIII clot stability NETs plasmin plasminogen activator PAI-2 antiplasmin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580213103321 |
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Kwaan Hau C
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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