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Oncolytic Virus Immunotherapy
| Oncolytic Virus Immunotherapy |
| Autore | Marchini Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (366 p.) |
| Soggetto topico |
Medicine
Clinical & internal medicine |
| Soggetto non controllato |
oncolytic viruses
melanoma immunotherapy checkpoint inhibitors combinatory therapy reovirus oncolytic virus adenovirus oncolytic virotherapy targeting immunogenic cell death αvβ6 integrin oncolytic adenovirus cancer immunotherapy multi-stage immunostimulatory arming HSV-1 clinical trials newcastle disease virus NDV cancer immune checkpoint inhibitor PD-1 PD-L1 CTLA-4 type I interferon herpes simplex virus retargeted virus tropism retargeting tumor checkpoint inhibitor vaccination antigen-agnostic vaccination HER2 parvovirus tumor microenvironment combination therapy glioblastoma pancreatic cancer colorectal cancer measles virus vector engineering immune checkpoint blockade antitumor immune response delivery genetic modification biomarkers personalized oncolyticvirotherapy class I HLA immunosurveillance immunoediting oncogenic signaling RAS DNA methyltransferase inhibitor (DNMTi) viral mimicry epigenetic silencing adoptive T cell therapy CAR T cell pancreatic ductal adenocarcinoma vesicular stomatitis virus small molecule cancer immune therapy cancer therapy |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566462203321 |
Marchini Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Plasma in Cancer Treatment
| Plasma in Cancer Treatment |
| Autore | Bogaerts Annemie |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (358 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
cell adhesion
plasma medicine oncology cold atmospheric plasma selectivity plasma-treated liquid dielectric barrier discharge pancreatic cancer pancreatic stellate cells immunogenic cell death dendritic cells cell communication extracellular matrix (ECM) reactive oxygen and nitrogen species (ROS) tumour microenvironment (TME) extracellular vesicles communication junctions three-dimensional in vitro culture models apoptosis breast cancer genome-wide expression reactive oxygen species anticancer drugs screening tumor spheroids combination therapy kINPen reactive oxygen and nitrogen species ROS cancer non-thermal atmospheric pressure plasma (NTP) indirect treatment plasma-treated phosphate-buffered saline electroporation electric pulses pulsed electric field amplitude melanoma long-lived reactive species bone cancer osteosarcoma reactive species plasma-activated liquid Ringer's saline organotypic model nonthermal biocompatible plasma soft jet plasma human glioblastoma p38/MAPK pathway tissue penetration non-thermal plasma non-invasive plasma treatment (NIPP) cervical intraepithelial neoplasia (CIN) Raman imaging Raman microspectroscopy Plasma lipid interactions cold physical plasma radiation therapy radio-frequency discharge PARP-inhibitor olaparib DNA-damage gold quantum dots plasma nanomaterials cellular uptake invasiveness cold atmospheric pressure plasma plasma-activated Ringer's lactate solution ovarian cancer cytotoxicity plasma-activated liquids multicellular tumor spheroids long-lived reactive oxygen and nitrogen species high frequency electrosurgery plasma treatment cold atmospheric plasma (CAP) free radicals cancer selectivity cervical cancer treatment cervical intraepithelial neoplasia cholangiocarcinoma cold plasma innovative therapy tumor cells macrophages plasma selectivity plasma jet |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557527603321 |
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Bogaerts Annemie
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases
| Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases |
| Autore | Rustum Youcef M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (166 p.) |
| Soggetto non controllato |
isoselenourea
malignant chemotherapeutics epigenetics antitumor activity methylseleninic acid mTOR inhibitors tumor heterogeneity hypoxia ER stress melanoma EMT lipid peroxidation immune evasion hypoxia-inducible factors (HIFs) selenium-binding protein 1 glutathione DNA damage hSP56 apoptosis tocopherol anticancer viability SELENBP1 selenium clear-cell renal cell carcinoma microRNAs SBP1 entosis PD-L1 miRNA cancer stem cells cell plasticity disease clear cell renal cell carcinoma HIF head and neck cancer selenium species VEGF STAT3 hypoxia-inducible factor methylselenocysteine anticancer agent Se-containing nanoparticles DNA damage and repair radiation seleno-l-methionine cancer tumor microenvironment methylselenoesters |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346851003321 |
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Rustum Youcef M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Polyamine Metabolism in Disease and Polyamine-Targeted Therapies
| Polyamine Metabolism in Disease and Polyamine-Targeted Therapies |
| Autore | Murray-Stewart Tracy |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (240 p.) |
| Soggetto non controllato |
protein synthesis in cancer
neuroblastoma epigenetics Drosophila imaginal discs pneumococcal pneumonia transgenic mice spermidine/spermine N1-acetyl transferase ?-difluoromethylornithine MYC skeletal muscle protein expression curcumin colorectal cancer autophagy human embryonic kidney 293 (HEK293) melanoma tumor immunity Snyder-Robinson Syndrome Streptococcus pneumoniae B-lymphocytes autoimmunity spermine oxidase cell differentiation diferuloylmethane immunity antizyme transgenic mouse polyamine hirsutism chemoprevention CRISPR transglutaminase polyamine analogs NF-?B spermine synthase atrophy aging oxidative stress mast cells African sleeping sickness pancreatic ductal adenocarcinoma eflornithine carcinogenesis ornithine decarboxylase polyamine transport inhibitor putrescine neutrophils spermidine untranslated region spermine polyphenol M2 macrophages polyamine transport system metabolism difluoromethylorthinine DFMO antizyme inhibitors capsule polyamine transport eosinophils MCF-7 cells difluoromethylornithine polyamine metabolism mutant BRAF polyamines cadaverine proteomics airway smooth muscle cells breast cancer X-linked intellectual disability complementation T-lymphocytes bis(ethyl)polyamine analogs antizyme 1 cancer osteosarcoma |
| ISBN | 3-03921-153-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367757003321 |
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Murray-Stewart Tracy
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Preclinical Evaluation of Lipid-Based Nanosystems
| Preclinical Evaluation of Lipid-Based Nanosystems |
| Autore | Silva Ana Catarina |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (351 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
nanostructured lipid carriers (NLC)
formulation optimization rivastigmine quality by design (QbD) nasal route nose-to-brain N-alkylisatin liposome urokinase plasminogen activator PAI-2 SerpinB2 breast cancer liposomes target delivery nanosystem FZD10 protein colon cancer therapy supersaturation silica-lipid hybrid spray drying lipolysis lipid-based formulation fenofibrate mesoporous silica oral drug delivery hyaluronic acid drug release light activation stability mobility biocorona dissolution enhancement phospholipids solid dosage forms porous microparticles nanoemulsion(s) phase-behavior DoE D-optimal design vegetable oils non-ionic surfactants efavirenz flaxseed oil nanostructured lipid carriers nanocarrier docohexaenoic acid neuroprotection neuroinflammation fluconazole Box‒Behnken design nanotransfersome ulcer index zone of inhibition rheological behavior ex vivo permeation nanomedicine cancer doxorubicin melanoma drug delivery ultrasound contrast agents phospholipid coating ligand distribution cholesterol acoustic response microbubble lipid phase dialysis ammonia intoxication cyanocobalamin vitamin B12 atopic dermatitis psoriasis transferosomes lipid vesicles skin topical delivery oligonucleotide self-emulsifying drug delivery systems hydrophobic ion pairing intestinal permeation enhancers Caco-2 monolayer clarithromycin solid lipid nanoparticles optimization permeation pharmacokinetics follicular targeting dexamethasone alopecia areata lipomers lipid polymer hybrid nanocapsules biodistribution skin ethyl cellulose |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557544303321 |
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Silva Ana Catarina
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Sex Hormone Receptor Signals in Human Malignancies
| Sex Hormone Receptor Signals in Human Malignancies |
| Autore | Miyamoto Hiroshi |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (152 p.) |
| Soggetto non controllato |
FOXA1
COBRA1 estrogen progesterone receptor negative mutational profiling heterogeneous nuclear ribonucleoprotein K estrogen receptor alpha salivary gland tumors castration-resistant prostate cancer ELK1 fibroblasts androgen receptor melanocytes drug screening and proteomics PI3K pathway NELFB therapeutic targets immunohistochemistry androgen deprivation therapy ovarian cancer estrogen receptor epidermal growth factor receptor ethinylestradiol melanoma breast cancer keratinocytes G-protein coupled estrogen receptor prognosis levonorgestrel ultraviolet radiation sex hormone receptors upper urinary tract urothelial carcinoma CRPC nuclear factor erythroid 2-related factor 2 TP53 |
| ISBN | 3-03921-174-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367756503321 |
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Miyamoto Hiroshi
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Synthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications
| Synthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications |
| Autore | Doti Nunzianna |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
polymers
peptidomimetics AFM transfection molecular modelling peptide α-helix hydrocarbon stapling ring-closing metathesis i,i + 1 staple X-ray structure deferoxamine RGD peptides integrins radiodiagnostics PET imaging retro-inverso peptides anticancer peptides drug delivery peptide antigens Aβ IAPP antimicrobial peptides peptides diagnostic ELISA microarray PET SPECT imaging diagnostic non-imaging diagnostic amphiphilic peptides non-viral gene delivery nanocarrier peptide self-assemblies stimuli responsive SARS-CoV-2 FRET molecular docking molecular dynamics MM-GBSA drug repurposing antiviral cancer cyclic peptide integrin αvβ3 ALOS4 melanoma fluorescent peptide environment-sensitive fluorophore peptide labeling luciferin membrane-binding peptide antimicrobial peptide antitumor peptide RGD peptide antiproliferative activity chirality conformational analysis density functional theory (DFT) ferrocene hydrogen bonds peptidomimetic X-ray protein–protein interactions (PPIs) voltage-gated Na+ (Nav) channels fibroblast growth factor 14 (FGF14) medium spiny neurons (MSNs) nucleus accumbens (NAc) neurotherapeutics cyclophilin A (CypA) apoptosis-inducing factor (AIF) human neuroblastoma SH-SY5Y cells staurosporine-mediated cell death AIF(370-394) peptide caspase-3 PARP antifungal antibacterial peptide-based therapies synthetic peptides |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Synthetic Peptides and Peptidomimetics |
| Record Nr. | UNINA-9910580210803321 |
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Doti Nunzianna
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeting STAT3 and STAT5 in Cancer
| Targeting STAT3 and STAT5 in Cancer |
| Autore | Moriggl Richard |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (578 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
multiple myeloma
STAT3 S3I-1757 nanoparticle CD38 siRNA/RNAi polyethylenimine PEI lipopolyplex siRNA delivery glioma glioblastoma STAT5 AKT ERK1/2 prolactin androgens prostate cancer knockout escape mechanisms stem/progenitor cells cell hierarchy cancer CD4+ T cells CD8+ T cells myeloid cells immune check point hepatitis C virus (HCV) cirrhosis hepatocellular carcinoma (HCC) endoplasmic reticulum (ER) stress oxidative stress (OS) unfolded protein response (UPR) microRNA-122 (miR-122) nuclear factor erythroid 2-related factor 2 (NRF2) signal transducer and activator of transcription 3 (STAT3) hepatocyte nuclear factor 4 alpha (HNF4A) solid cancers cell cycle apoptosis inflammation mitochondria stemness tumor suppression melanoma autoimmune disease immunotherapy tumor-immune cell interactions breast cancer PD-L1 M2 macrophages NK cells STAT3 inhibitor XIII hedging transaction costs dynamic programming risk management post-decision state variable cancer progression cancer-stem cell cytokine therapy resistance metastasis immunosuppression tumor microenvironment proliferation tyrosine kinase 2 JAK family of protein tyrosine kinases signal transducer and activator of transcription cytokine receptor signaling gain-of-function mutation tumorigenesis ADAM17 interleukin-6 trans-signaling epidermal growth factor receptor (EGF-R) shedding metalloprotease tumor necrosis factor alpha (TNFα) inflammation associated cancer colon cancer lung cancer SH2 domain mutations autosomal-dominant hyper IgE syndrome inflammatory hepatocellular adenomas T-cell large granular lymphocytic leukemia T-cell prolymphocytic leukemia growth hormone insensitivity syndrome nuclear pore complex nuclear transport receptors nucleocytoplasmic shuttling targeting tumor-associated macrophages adoptive T cell therapy immune suppression STAT transcription factors JAK STAT T-PLL T-cell leukemia meta-analysis STAT5B signaling small-molecule inhibitors cancer models companion animals comparative oncology pharmacological inhibitor STAT5 signaling chemotherapy resistance myeloid leukemia heat shock proteins chaperones stabilization targeted therapy ovarian cancer hematopoietic cancers therapeutic targeting pharmacological inhibitors mTOR Bone Marrow Failure Syndromes lymphocytes lymphoma T-cells RHOA NGS MPN JAK2 V617F neoplastic stem cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557623503321 |
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Moriggl Richard
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday: Natural Products in Modern Drug Discovery
| Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday: Natural Products in Modern Drug Discovery |
| Autore | Hussain Hidayat |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (360 p.) |
| Soggetto topico |
Research & information: general
Chemistry Organic chemistry |
| Soggetto non controllato |
multi-component reaction
fusidic acid TEMPO-conjugate electron paramagnetic resonance (EPR) spectroscopy caspase-3 incomptine A sesquiterpene lactone Decachaeta incompta cytotoxic activity iTRAQ apoptosis ROS production violacein hepatocellular carcinoma proliferation stemness natural products tumor microenvironment (TME) lung cancer phytochemicals botanical agents steroidal alkaloids solanidane alkaloids demissidine solanidine flavonoids coronavirus SARS-CoV-2 SARS-CoV MERS-CoV anticancer activity apoptosis resistance ophiobolin A polygodial Wittig reaction melanoma tumor heterogeneity pregnancy anti-tumor peptides in vitro model medicinal herbs cancer treatment cancer stem cells drug resistance metastasis RCE-4 PCD ATG 4B the Bcl-2-Beclin 1 complex Sparticola junci structure elucidation ECD-TDDFT COX inhibitory molecular docking antiproliferative cytotoxic Sepedonium ampullosporum peptaibols ampullosporin glutamic acid methyl ester solid-phase peptide synthesis antifungal anticancer target identification kaempferol docking DARTS Src breast cancer butein frondoside-A STAT3 angiogenesis invasion viability tumor growth marine fungi Cosmospora sp soudanone Magnaporthe oryzae co-culture phytopathogen molecular networking metabolomics bispecific antibody Trypsiligase click chemistry biorthogonal chemistry antibody engineering |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday |
| Record Nr. | UNINA-9910585945403321 |
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Hussain Hidayat
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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