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Circulating Tumor Cells: Finding Rare Events for A Huge Knowledge of Cancer Dissemination
| Circulating Tumor Cells: Finding Rare Events for A Huge Knowledge of Cancer Dissemination |
| Autore | Alix-Panabieres Catherine |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (366 p.) |
| Soggetto non controllato |
FOLFIRINOX
immunofluorescence imaging AR-V7 circulating tumour cells chemoradioresistance CTC-based treatment decisions rVAR2 immunophenotyping immune system CellSearch® flow cytometry clinical trials circulating tumor DNA synaptophysin stem cells colorectal cancer melanoma CTC biology platelets AR CTC capture technology castration resistant prostate cancer (CRPC) PD-L1 expression rovalpituzumab tesirine HMB-45 thymidylate synthase ctDNA tumor cell dissemination solid cancers metastasis locally advanced rectal cancer miRNA epithelial-to-mesenchymal transition (EMT) NSCLC tumor biomarkers tumor stem cells circulating tumor cells major histocompatibility complex class I (MHCI) bone marrow heterogeneity cerebrospinal liquid biopsy fish glioma in vivo flow cytometry colorectal surgery CellSearch single-cell analysis disseminated tumor cells EasyCount slides microsatellite instability circulating plasma cells circulating leukemia cells ARV7 SLUG androgen receptor metastatic colorectal cancer leukocyte-derived extracellular vesicles prostate cancer (PCa) neutrophils liquid biopsy enzalutamide CD133 enrichment and detection technologies biomarkers immune checkpoint inhibitors biomarker RAD23B microbiome integrin B1 ACCEPT emboli small-cell lung carcinoma EPISPOT microfluidics early breast cancer circulating tumor cells (CTC) tumor-initiating cells (TICs) immunomodulation xenograft models CTC-derived xenografts malaria circulating tumor cells (CTCs) clinical utility exosomes liquid surgery ctRNA CTCs epithelial-mesenchymal transition targeted therapy hematological cells gene expression analysis hepatocellular carcinoma (HCC) breast cancer EpCAM enrichment prostate cancer CTC abiraterone fibronectin CTC-derived ex vivo models CTMat chromogranin A CTM exosome |
| ISBN | 3-03928-699-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Circulating Tumor Cells |
| Record Nr. | UNINA-9910404091403321 |
Alix-Panabieres Catherine
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Deep Learning in Medical Image Analysis
| Deep Learning in Medical Image Analysis |
| Autore | Zhang Yudong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (458 p.) |
| Soggetto non controllato |
interpretable/explainable machine learning
image classification image processing machine learning models white box black box cancer prediction deep learning multimodal learning convolutional neural networks autism fMRI texture analysis melanoma glcm matrix machine learning classifiers explainability explainable AI XAI medical imaging diagnosis ARMD change detection unsupervised learning microwave breast imaging image reconstruction tumor detection digital pathology whole slide image processing multiple instance learning deep learning classification HER2 medical images transfer learning optimizers neo-adjuvant treatment tumour cellularity cancer breast cancer diagnostics imaging computation artificial intelligence 3D segmentation active surface discriminant analysis PET imaging medical image analysis brain tumor cervical cancer colon cancer lung cancer computer vision musculoskeletal images lung disease detection taxonomy convolutional neural network CycleGAN data augmentation dermoscopic images domain transfer macroscopic images skin lesion segmentation infection detection COVID-19 X-ray images bayesian inference shifted-scaled dirichlet distribution MCMC gibbs sampling object detection surgical tools open surgery egocentric camera computers in medicine segmentation MRI ECG signal detection portable monitoring devices 1D-convolutional neural network medical image segmentation domain adaptation meta-learning U-Net computed tomography (CT) magnetic resonance imaging (MRI) low-dose sparse-angle quantitative comparison |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557435103321 |
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Zhang Yudong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor
| Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor |
| Autore | Holzmann Klaus |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (276 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
FGFR4
FGF19 gene regulation cancer signaling anticancer FRS2 FGFR NVP-BGJ398 LY2874455 sarcoma cancer-associated fibroblasts GPER breast cancer estrogen FGFR1 FGF2 optogenetics ERK AKT receptor kinase neurite outgrowth HEK293 PC12 fibroblast growth factor receptors signaling receptor cross-talk coreceptor membrane proteins FGFR2 ERK1/2 phosphorylation serine negative feedback loop cancer prognosis HCC inhibitors FGF fibroblast growth factor autocrine signaling skin melanoma squamous and basal cell carcinoma seborrheic keratosis targeted therapy resistance structure kinase inhibitor gastric cancer monoclonal antibody small molecule FGFR2c autophagy keratinocyte MTOR JNK1 review malignant glioma brain cancer astrocytoma Sprouty proteins FGF-mediated signaling tumor suppressor tumor promoter malignant pleural mesothelioma overall survival immunohistochemistry infigratinib sensitivity FGF8 FGF18 adenocarcinoma of the esophagogastric junction neoadjuvant therapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Fibroblast Growth Factor Receptor |
| Record Nr. | UNINA-9910557898903321 |
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Holzmann Klaus
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Immunotherapy, Tumor Microenvironment and Survival Signaling
| Immunotherapy, Tumor Microenvironment and Survival Signaling |
| Autore | Golubovskaya Vita |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (376 p.) |
| Soggetto topico |
Medicine
Clinical & internal medicine |
| Soggetto non controllato |
Autophagy
colorectal cancer immunotherapy tumor stroma tumor microenvironment immune checkpoint inhibitors chemotherapy tyrosine kinase inhibitors angiogenesis check point inhibitors programmed cell death protein 1 programmed cell death 1 ligand 1 cardiotoxicity lung metastasis CAR-T hypoxia tumor microenvironment CD19 BCMA cancer melanoma immune escape antigen loss chimeric antigen receptor electroporation lentivirus lentiviral transduction macrophages leukemia cells lytic peptides targeted therapy dendritic cells pathogenesis risk factors breast cancer resistance checkpoint targeted treatment personalized medicine pediatric solid tumors chimeric antigen receptors cancer vaccines oncolytic viral therapy immunomodulation DCLK1 tumor stem cells clonogenicity mitochondria mitochondrial transfer tunneling nanotubes triple-negative breast cancer immune checkpoint inhibitor combination therapy cancer nanomedicine tumor antigens cancer metabolism cancer immunotherapy nanoparticles immunotherapeutic agent immunomodulators tuft cells cancer stem cells immunotherapies myeloid-derived suppressor cells regulatory T cells crosstalk tumor immune evasion cell-cell contact β2 integrins CD18 CD11 CAR-T cells CD37 cell therapy tumor antigen lymphoma CAR macrophage CAR T cell solid tumors immunometabolism miRNA immunogenic cell death |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580205403321 |
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Golubovskaya Vita
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
apoptosis
fucoidan hepatocellular carcinoma reactive oxygen species 3-alkylpyridinium polymers nicotine nicotinic acetylcholine receptor non-small cell lung carcinoma melanoma sinulariolide proteomic mitochondria caspase cascade marine fungus sediment anthranilic acid Penicillium paneum cytotoxicity dibromotyrosine mitochondrial dysfunction oxidative stress topoisomerase epigonal organ bonnethead shark Jurkat tumor cell line hippuristanol PEL AP-1 STAT3 Akt colorectal cancer marine mollusc brominated indoles shrimp chemoprevention fatty acids carotenoids cancer nanoparticle osteosarcoma lung metastasis elisidepsin lipid rafts hydroxylated lipids fatty acid 2-hydroxylase cooperative binding membrane permeabilization marine organisms polysaccharides anticancer anticarcinogenic mechanisms of action fumigaclavine C anti-proliferation mitochondrial pathway anti-cancer anti-proliferative carotenoid cell cycle arrest fucoxanthin azoxymethane bioactive natural product isatin in vivo model Marthasterias glacialis L. palmitic acid ER-stress CHOP Antibody Drug Conjugates (ADCs) marine antitumor agents clinical trials approved antitumor agents AD0157 angiogenesis marine drug pyrrolidinedione secondary metabolites cancer preventive chemopreventive trabectedin plitidepsin tumor-associated macrophages tumor microenvironment preclinical anticancer immunity antiangiogenesis fascaplysin cyclin-dependent kinase small cell lung cancer camptothecin poly(ADP-ribose)-polymerase inhibitor breast cancer seaweed therapeutic compounds autophagy marine drugs autophagy inhibitors autophagy inducers macrolide programmed cell death energy stress araguspongine C c-Met HER2 gemcitabine pazopanib phase I safety soft tissue sarcoma pachastrissamine jaspine B carbocyclic analogue sphingosine kinase inhibitor molecular modeling ET-743 DNA minor groove binder soft tissue sarcoma chemotherapy bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) anti-metastatic activity cell adhesion β1-integrin FAK BEL-7402 cell triterpene glycosides sea cucumbers antitumor activities arrest of cell cycle antibacterial marangucyclines deep-sea Streptomyces sp. SCSIO 11594 LS-1 SNU-C5/5-FU TGF-β signaling carcinoembryonic antigen kalkitoxin Moorea producens mitochondria toxin VEGF angiogenesis inhibitor hypoxia-inducible factor-1 HIF-1 Lyngbya majuscula marine metabolites SZ-685C nonfunctioning pituitary adenomas Ecklonia cava phlorotannins dieckol migration sipholenol A ABC transporter multidrug resistance P-gp/ABCB1 BCRP/ABCG2 MRP1/ABCC1 marine natural products glioblastoma xyloketal B proliferation TRPM7 marine compound ribosomal protein genes snoRNA FAU RPS30 SNORA62 evolution Porifera Penicillium brevicompactum Brevianamide Mycochromenic acid derivative antifouling Caribbean sponge plakortide endoperoxide leukemia multi-drug resistant leukemia Sarcophyton ehrenbergi soft coral terpenes cembranoids cytotoxic activity molecular docking uveal melanoma oxidative stress virtual screening Topo I inhibitor low toxic natural product Ulva fasciata selenium-containing polysaccharide-protein complex pseudopterosin NF-κB p65 inflammation cytokine release IL-6 TNFα MCP-1 glucocorticoid receptor paulomycins Micromonospora antitumor Cantabrian Sea-derived actinobacteria puupehenones sponges antiangiogenic antitumoral porifera/sponge cancer genes molecular oncology bromophenol molecular mechanisms cell cycle PI3K/Akt p38/ERK ROS human lung cancer glycosaminoglycans antiproliferative heparan sulphate gliotoxin NSCLC adriamycin resistance Sepia ink polysaccharides antitumour chemosensitization anticoagulation sea anemone drug discovery endothelial cells RGD motif kunitz type inhibitor prostate cancer antioxidant natural marine compounds marine biotechnology microalgae marine sponges Aeroplysinin Isofistularin pheochromocytoma and paraganglioma metastasis cancer progression cell adhesion molecules integrin β1 hypoxia phycocyanin non-small cell lung cancer NF-κB signaling marine-derived drugs bioanalysis chromatography manzamine A epithelial-mesenchymal transition lung cancer circulating tumor cells signal transduction cisplatin Lampetra morii buccal gland cystatin F anti-angiogenesis cystatin superfamily Antimicrobial peptide (AMP) Tilapia piscidin 4 (TP4) non-small cell lung cancer (NSCLC) itampolin A FBDD p38α novel inhibitor tetracenomycin X cyclin D1 proteasomal degradation p38 c-JUN λ-carrageenan heparanase anticoagulant depolymerisation cell migration Aspergillus naphthopyrones endophytic fungus Leathesia nana mangrove-derived actinomycete ansamycins divergolides apoptosis-inducing activity actinomycin EMT invasion low molecular weight fucoidan extract N-Ras neuroblastoma-rat sarcoma Cancer programmed cell death-ligand 1 programmed cell death-ligand 2 human sarcoma cell line (HT1080 cells) human normal diploid fibroblast (TIG-1 cells) chimera chemical conjugation anticancer agent hybridization α9-nicotinic acetylcholine receptors (nAChRs) breast cancer cells αO-conotoxin GeXIVA targeted therapy gorgonian Leptogorgia humulane sesquiterpenoids anticancer activity 12-deacetyl-12-epi-scalaradial HeLa cells Nur77 MAPK/ERK pathway Mycalin A C15 acetogenins synthetic analogues antiproliferative activity A375 and HeLa cell lines polyoxygenated steroids sponge Haliclona gracilis Thalassia testudinum thalassiolin B polyphenols CYP1A1 benzo[a]pyrene JNK1/2 natural products synergism A549 cells cytoskeleton P2X7 receptor pollution anti-angiogenic gene expression HSP90 inhibitor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
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Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondria-targeted drug delivery
| Mitochondria-targeted drug delivery |
| Autore | Kopecka Joanna |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (290 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
retinal ischemia
blood-brain barrier endothelial reactive oxygen species oxidative stress tunneling nanotubules neuron central nervous system inflammation hypoxia anticancer peptide (ACP) antimicrobial peptide (AMP) anticancer peptides antimicrobial peptides host defense peptides prediction random forest mitochondria mitochondrial DNA mitochondrial disorders pharmacological therapy gene therapy precision medicine cardiovascular disease drug delivery mitochondria dysfunctions nanocarriers oxoglutarate carrier malate-aspartate shuttle cancer metabolism ATP production diphenyleneiodonium NADPH-oxidase differentiation proliferation mitochondria-targeted antioxidants LPS mitochondrial ROS antitumor agents fluorescence lifetime imaging medicinal chemistry metabolic drug mitochondrial carrier melanoma plumbagin cytotoxic effect metabolism cholesterol lipid raft mitochondrial permeability transition pore alkylphospholipid analog edelfosine mitochondrial oncometabolites cancer drug resistance mitochondrial disease heteroplasmy mitochondrial gene delivery |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576881503321 |
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Kopecka Joanna
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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mTOR Signaling in Metabolism and Cancer
| mTOR Signaling in Metabolism and Cancer |
| Autore | Huang Shile |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
mTOR
histone deacetylase prostate cancer integrins adhesion invasion cell metabolism T cells Foxp3 Acute Lymphoblastic leukemia targeted therapy metabolism cell signalling mTOR signalling head and neck cancer mutant genes biomarkers targeted therapies clinical trials cancers inhibitors photodynamic therapy PI3K Akt skin cancers phytochemicals melanoma basal cell carcinoma squamous cell carcinoma Merkel cell carcinoma TNBC eribulin PI3K/AKT/mTOR everolimus combination synergy mTOR signaling tissue regeneration neuron muscle liver intestine hematologic malignancies regulatory T cells tumor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557107203321 |
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Huang Shile
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Natural Compounds as New Cancer Treatments
| Natural Compounds as New Cancer Treatments |
| Autore | Barrajon Enrique |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (128 p.) |
| Soggetto non controllato |
microbiota
treatment sulforaphane synergy epigenetic natural compound xenohormesis anticancer miR-663 tyrosine kinase inhibitors acetylation epidemiology double-blinded inflammation bladder cancer polypharmacology animal model synbiotics resveratrol royal jelly 5-aza-2'-deoxycytine saponins phenolics cardiovascular disease antioxidant colorectal cancer trypsin inhibitors seeds green tea Gac randomized clinical trial melanoma adverse events extraction microbiome Momordica cochinchinensis freeze dried extract renal cell carcinoma methylation cancer probiotics |
| ISBN | 3-03921-366-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367758003321 |
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Barrajon Enrique
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Advances in Melanoma
| New Advances in Melanoma |
| Autore | Larribère Lionel |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (148 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
melanoma
targeted therapies BRAF druggable mutations real-time PCR NGS assay immune escape microRNA transporter associated with antigen processing incidence population-based study epidemiology Spain skin cancer single-cell transcriptome sequencing treatment response pseudotime analysis treatment ubiquitination miRNAs embryogenesis melanoblasts melanoblast NF1 transcriptome RNAseq Trp-1 metastasis animal models lung mice |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566475303321 |
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Larribère Lionel
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Prognostic and Predictive Markers in Cancer Progression
| New Prognostic and Predictive Markers in Cancer Progression |
| Autore | Costantini Susan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (294 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
MSI2
OSCC oral cancer musashi 2 prognosis N-cadherin EMT breast cancer new metastasis eribulin blood biomarker bladder cancer immune checkpoint inhibitor CD8+ T effector cells microRNA biomarkers head and neck cancer laryngeal cancer prediction metastasis lifestyle habit chemo-/radio resistance therapeutic target AKT AR castration-resistant prostate cancer (CRPC) MAPK mTOR PI3K prostate cancer therapeutic resistance WNT miRNA melanoma melanoma resistance to MAPK/MEK inhibitors resistance to immune checkpoint inhibitors TNBC BRCA1/2 HRR PDL1 TILs PI3KCA PTEN CTCs CSC pancreatic cancer K-RAS oncogene oncogene dependency targeted therapies genomic mutations transcriptomics metabolomics selenoproteins cancer HUB nodes major histocompatibility complex (MHC) human leukocyte antigen (HLA) antigen processing machinery (APM) molecules carcinogenesis tumor predisposition cancer immunotherapy pheochromocytoma paraganglioma head and neck neoplasms head and neck tumors genetic syndromes mutations hyperglycemia cardioncology nivolumab cytokines cardiotoxicity acetyltransferase cancer prognosis NAA10 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557794803321 |
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Costantini Susan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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