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Therapeutic Potential of Plant Secondary Metabolites in the Treatment of Diseases and Drug Development
| Therapeutic Potential of Plant Secondary Metabolites in the Treatment of Diseases and Drug Development |
| Autore | Drašar Pavel B |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (334 p.) |
| Soggetto topico |
Technology: general issues
Chemical engineering |
| Soggetto non controllato |
Cannabis sativa (Cannabis)
cannabinoids tetrahydrocannabinol (THC) cannabidiol (CBD) cannabinoid receptors (CB1 and CB2) Papaver somniferum (opium poppy) secondary metabolites ursolic acid NSCLC tumorsphere EGFR STAT3 MMP2 PD-L1 MAFLD tanshinone IIA phytochemical lipogenesis lipid accumulation LXRα malaria quinine chloroquine artemisinin onchocerciasis ivermectin moxidectin cancer vincristine vinblastine anabolic diabetes Duchenne muscular dystrophy β-ecdysone ecdysteroid ecdysterone Mas1 osteoporosis sarcopenia COVID-19 cardiometabolic diseases respiratory diseases natural product SARS-CoV-2 lung cancer United States Food and Drug Administration-approved drug natural remedy triterpenoid molecular ribbon Huisgen 1,3-dipolar cycloaddition amide bond multifunctional PEG3 derivative antimicrobial activity anti-HIV activity cytotoxicity supramolecular self-assembly phytocannabinoids cannabichromene thermos-TRPs TRPA1 α,α-dimethylheptyl effect betulinic acid BODIPY bevirimat cell-cycle fluorescent microscopy maturation inhibitor capsaicinoids endocannabinoidome microbiota overweight obesity food intake lipidomics metabolism alkaloids membrane fusion viral fusion inhibitor antiviral therapy curcumin cancer cells bioavailability curcumin derivatives curcumin analogues curcumin delivery systems natural product synthesis lignans inflammation NF-κB inhibition |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580203103321 |
Drašar Pavel B
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Toxicological Effects of Mycotoxins on Target Cells
| Toxicological Effects of Mycotoxins on Target Cells |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (218 pages) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Destruxin A
Bombyx mori binding protein BmTudor-sn Bm12 cell Ochratoxin A (OTA) human Stem Cells mycotoxins cells cytotoxicity cell culture T-2 toxin HT-2 toxin apoptosis autophagy endophyte fungi neurotoxin lolitrems ochratoxin A beauvericin mixtures HepG2 cells genotoxicity cell cycle Fusarium Aspergillus Penicillium Alternaria emerging mycotoxin in vitro IPEC-J2 occurrence data trichothecene biosynthetic pathway acetyltransferase deacetylase deoxynivalenol 3-acetyldeoxynivalenol isotrichodermol isotrichodermin differentiated Caco-2 cells cell apoptosis transcriptome analysis hepatocyte chicken acute toxicity combined toxicity cell protection silibinin in silico prediction co-culture models mycotoxin interaction Loewe additivity combination index isobologram Chou-Talalay method MixLow IPEC-J2 cells RNA-seq inflammation MAPKs |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557291503321 |
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation
| Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation |
| Autore | Ciccodicola Alfredo |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (356 p.) |
| Soggetto non controllato |
transcription factor
transcription self-incompatibility cytogenetics epigenetics selenocysteine tea AP-2? nonsense-mediated decay transcriptomics Akt1 promoter cell metabolism pediveliger larvae Patau Syndrome tristetraprolin (TTP) long non-coding RNA (lncRNA) pregnancy G-quadruplex glioblastoma placenta PRDM gene family circRNA-disease associations bioadhesive gene expression Crassostrea gigas transcription regulation cell differentiation RNA interference transcriptome inflammatory response FOXO1 Adiponectin liquid chromatograph-tandem mass spectrometer (LC-MS/MS) selenium selenocysteine insertion sequence inflammation selenoproteins research methods nutritional status structures and functions CRISPR/Cas9 fertilization melanin differentially expressed genes tyrosinase posttranscriptional regulation major depressive disorder human malignancies pathway CDKN1C transcription factors p57Kip2 enhancer activity mouse disorders high-throughput RNA sequencing (RNA-Seq) TCGA data analysis RNA-seq heterogeneous network insect and drug design therapeutic targets mechanisms obesity Pacific oyster Rsh regulon common pathway Pax3 somatic mutations nutrition molecular docking bioinformatics interactome long non-coding RNAs transcriptional regulation Pteria penguin (Röding Adiponectin receptors transcriptome profiling 1798) N-acyl-l-homoserine lactone ppGpp tumorigenesis sphingomonads human disease adenosine and uridine-rich elements (AREs) progress and prospects miR-25-3p acute leukemia Novosphingobium pentaromativorans US6-1 microscopy cancer molecular pathways causal inference |
| ISBN | 3-03921-266-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Transcriptional Regulation |
| Record Nr. | UNINA-9910346689003321 |
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Ciccodicola Alfredo
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Transcriptome and Genome Analyses Applied to Aquaculture Research
| Transcriptome and Genome Analyses Applied to Aquaculture Research |
| Autore | Pereiro Patricia |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (554 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Fisheries & related industries |
| Soggetto non controllato |
RNA-Seq
lncRNAs Dicentrarchus labrax viral infection nodavirus immune response fish T lymphocytes infection malnutrition inflammation aquaculture histopathology immunohistochemistry enteromyxosis Philasterides dicentrarchi turbot transcriptomics Chinese mitten crab Eriocheir sinensis transportome transporters salinity osmoregulation transcriptome meta-analysis gills short pentraxins c-reactive protein zebrafish transcript expression antiviral SVCV rag1 mutants skin mucosal immunity hypoxia hypo-metabolic state growth swimming performance metabolic landmarks muscle transcriptome glycolysis lipid metabolism protein turnover gilthead sea bream hepatopancreas necrosis disease metatranscriptomics sequencing hepatopancreatic flora teleost B cells single cell transcriptomics immunoglobulins immune markers transcription factors long non-coding RNAs hepatic transcript expression salmon microarray omega-6/omega-3 ratio nutrigenomics fatty acids liver muscle Misgurnus anguillicaudatus sexual size dimorphism polyploid size dimorphism comparative transcriptome gene expression edible red sea urchin Loxechinus albus RNA-seq reference transcriptome Chinese soft-shelled turtle Aeromonas hydrophila hemorrhagic sepsis molecular immunopathogenesis tripartite motif proteins B30.2 domain antiviral immunity Ctenopharyngodon idella grass carp reovirus metamorphosis brain RNA sequencing intermuscular bone development Megalobrama amblycephala Oreochromis niloticus histological structure Atlantic salmon smoltification genome mRNAs miRNAs sox family genes Pelodiscus sinensis estradiol pseudo-female sex-related heterosis heterobeltiosis environment transgressive genes conserved miRNA high-throughput sequencing lumpfish novel miRNA RT-qPCR heat shock protein co-chaperon network salinity-alkalinity adaptation molecular evolution Lateolabrax maculatus genomics stress response HPI-axis neuroendocrine-immune interaction common carp poly-unsaturated fatty acid fatty acid elongase association study genomic selection bulked segregant analysis SNP association analysis joint effect seawater adaptation microRNAs small-RNA sequencing microarray transcriptome European seabass chronic inflammation opioid receptors immune status whole-transcriptome sequencing sex differentiation non-coding RNAs ceRNA red cusk-eel thermal stress liver transcriptome oxidative damage protein folding hepatic enzymes |
| ISBN | 3-0365-5921-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910637793503321 |
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Pereiro Patricia
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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TRP Channels in Health and Disease
| TRP Channels in Health and Disease |
| Autore | Dietrich Alexander |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (266 p.) |
| Soggetto non controllato |
transient receptor potential channels
photochromic ligands elementary immunology Purkinje cell EPSC substance P chemicals organ toxicity lymphocytes HSP70 physiology bioavailable inflammatory bowel disease platelets pollutants yeast regulatory T cells kinase Saccharomyces cerevisiae manganese cerebellum TRP channel NHERF inflammation nanoHPLC-ESI MS/MS TRPM7 chemical probes TRPM8 dorsal column nuclei TRPV2 TRPV3 calcitonin gene-related peptide TRPV1 ion channels transient receptor potential 2D gel electrophoresis MALDI-TOF MS(/MS) TRPV4 overproduction sulfur mustard oxidative stress graft versus host disease menthol topical chemosensor AP18 calcium signalling mucosal epithelium cuneate nucleus production platform TRPC channels ulcerative colitis channel structure xerostomia neutrophils cardiovascular system TRPC5 TRPC6 TRPC3 TRPC4 calcium signaling protein purification adipose tissue transient receptor potential (TRP) channels sodium TH17 diacylglycerol hypersensitivity TRPY1 GABAB HEK293 thrombosis ion channel TRPC pathophysiology SMAD toxicology endothelium calcium proteomics TRPA1 salivary glands TRP channels lipid mediators sensors radiation TRPM4 channel human medulla oblongata mGluR1 small molecules TRPC3 pharmacology |
| ISBN | 3-03921-083-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674009603321 |
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Dietrich Alexander
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ubiquitination in Health and Diseases
| Ubiquitination in Health and Diseases |
| Autore | Ishigami Tomoaki |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (292 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
deubiquitinase
degradation therapeutic target cancer hematopoiesis hematopoietic stem cells immune response regulation of gene expression ubiquitin system genetic diseases ubiquitin ligase deubiquitinases monoubiquitin signaling vesicular trafficking protein complex formation inflammation inhibitor innate immune interferon LUBAC NF-κB ubiquitin Parkinson’s disease dopa-responsive dystonia tyrosine hydroxylase α-synuclein fatty acid-binding protein 3 ubiquitination proteasomal degradation ubiquitin-proteasome system mitochondria E3 ubiquitin ligase MITOL/MARCH5 salt-sensitive hypertension Nedd4L/Nedd4-2 epithelial sodium channel aldosterone sensitive distal nephron excitation-transcription coupling RNF183 RNF186 RNF182 RNF152 RING finger mTOR endoplasmic reticulum stress osmotic stress ubiquitin code virus infection virus-host interaction tau protein semisynthesis disulfide-coupling polyubiquitin fibrils aggregation neurodegeneration deubiquitination inhibitors protein quality control proteolysis protein stabilization regulatory T cells mesenchymal stem cell cortical bone derived stem cell myocardial infarction blood pressure renal salt reabsorption vascular function ubiquitin proteasome system ubiquitin–proteasome pathway cilia ciliogenesis differentiation proliferation ciliopathy E3s DUBs UPS neurodegenerative disease immune-related diseases |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557356403321 |
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Ishigami Tomoaki
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Update on Nutrition and Food Allergy
| Update on Nutrition and Food Allergy |
| Autore | De Jong Nicolette W |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (202 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
cow's milk protein
peptides Caco-2 cell immunogenicity allergenicity glycation oral food challenge successful introduction children food allergy allergy cow's milk hens egg peanut hazelnut glutenin methylglyoxal allergic reaction gut microflora heat-processing skin-gut-axis cutaneous sensitization atopic dermatitis microbiota diet history allergenic protein thresholds eliciting dose bite size hen's egg birch pollen Bet v 1 OAS pear oral challenge seaweed inflammation oral diagnosis extracts oral allergy syndrome skin prick test specific IgE baked milk tolerance |
| ISBN | 3-0365-5348-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619471603321 |
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De Jong Nicolette W
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Updates in Management of SARS-CoV-2 Infection
| Updates in Management of SARS-CoV-2 Infection |
| Autore | Flisiak Robert |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (198 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
COVID-19
SARS-CoV-2 interleukin-6 tocilizumab therapy coronavirus disease 2019 cytokines severity prognosis mortality kidney failure rapid diagnostic test antigen detection Cytomegalovirus co-infections critical care liver markers inflammation morbidity personalized medicine liver functional tests COVID-19 pneumonia meta-analysis trial sequential analysis children clinical presentation coronavirus disease 2019 (COVID-19) epidemiology severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) clinical outcome symptomatology pandemic angiotensin 1 receptor (AT1R) AT1R concentration angiotensin II symptoms' severity diagnosis artificial intelligence medical imaging systematic umbrella review methodological credibility PCR test COVID-19 diagnosis Charlson Comorbidities Index cluster analysis longitudinal cluster individualized management |
| ISBN | 3-0365-5390-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619470303321 |
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Flisiak Robert
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Urological Cancer 2021
| Urological Cancer 2021 |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (328 pages) |
| Soggetto topico |
Research
Chemistry |
| Soggetto non controllato |
bladder cancer
radiotherapy radiosensitisation molecular subtypes preclinical studies bladder cancer cell lines latent cancer prostate cancer autopsy prognostic index prediction model mortality screening trial renal cell carcinoma PD-1 PD-L1 biomarkers immune checkpoint inhibitors prostatic neoplasms positron-emission tomography decision making tumor thrombus metastasectomy postoperative complications oncological outcomes radical cystectomy AHNAK2 prognosis dog comparative oncology inflammation prostatic atrophy preneoplastic lesion biomarker urine machine learning TRIPOD liquid biopsy glutaminase immunohistochemistry in situ methods prostate PSMA-RLT 177Lu-PSMA PSA mCRPC urinary bladder neoplasms Bacillus Calmette-Guérin (BCG) immunotherapy divergent differentiation variant morphology survival stereotactic body radiotherapy frail patients cancer metastasis genomic analysis microenvironment tumor ecology game theory fluorescence confocal microscopy prostate biopsy ablation margins focal therapy sphingosine 1-phosphate receptor 1 bladder carcinoma cell migration epithelial-mesenchymal transition FTY-720 OIP5 papillary renal cell carcinoma PLK1 tumorigenesis therapy image-guided magnetic resonance imaging ultrasonography biopsy abiraterone enzalutamide docetaxel novel hormonal therapies comparative effectiveness real-world treatment pattern metastatic prostate cancer epiplakin diagnosis advanced urothelial carcinoma immune checkpoint inhibitor prognostic tumour mutational board genomic signatures ctDNA inflammatory indices urothelial carcinoma frailty prognostic factor psoas muscle Hounsfield units |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576872803321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Venom and Toxin as Targeted Therapy
| Venom and Toxin as Targeted Therapy |
| Autore | Kwok Hang Fai (Henry) |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (180 p.) |
| Soggetto non controllato |
cane toad
B cell non-Hodgkin lymphoma Malaysian cobras complement system decay accelerating factor neuroblastoma atopic dermatitis complement dependent cytotoxicity antioxidant enzymes bacterial adhesion cancer therapy N. kaouthia anuran skin secretion frog Apis mellifera syriaca solid phase extraction bee venom phospholipase A2 (bvPLA2) disintegrin toad toxins immunotoxins ribosome-inactivating proteins antimicrobial peptide (AMP) drug design Moxetumomab pasudotox snake venom antiviral activity in vitro effects bombesin-related peptide oxidative stress biomarkers half-life blood vessel formation target therapy 2 MYCN indolealkylamines Huachansu membrane attack complex bouganin bee venom SEM anticancer activity antimicrobial peptide house dust mite extract (DFE) mannose receptor O. hannah bicarinalin gastric cells melittin LC-ESI-MS dermaseptin smooth muscle apoptosis anticancer N. sumatrana Helicobacter pylori inflammation immunotherapy atopic dermatitis (AD) immunotoxin mantle cell lymphoma clearance mass spectrometry Bougainvillea rRNA N-glycosylase activity fungal toxin skin inflammation targeted therapy 4-dinitrochlorobenzene (DNCB) Bee venom VEGF Chansu bufadienolides obsessive-compulsive disorder (OCD) BLF1 antimicrobial activity orellanine VB6-845 acute lymphoblastic leukemia ribosome-inactivating protein CD206 molecular cloning cancer CD22 eIF4A |
| ISBN | 3-03921-190-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367754703321 |
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Kwok Hang Fai (Henry)
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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