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STATs and IRFs in Innate Immunity: From Transcriptional Regulators to Therapeutic Targets
| STATs and IRFs in Innate Immunity: From Transcriptional Regulators to Therapeutic Targets |
| Autore | Lee Chien-Kuo |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (221 p.) |
| Soggetto topico |
Medicine
Immunology |
| Soggetto non controllato |
STAT
IRF innate immunity inflammation transcriptional regulation therapeutic target |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | STATs and IRFs in Innate Immunity |
| Record Nr. | UNINA-9910557304103321 |
Lee Chien-Kuo
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Stem Cell Research on Cardiology
| Stem Cell Research on Cardiology |
| Autore | David Robert |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (356 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Fabry disease
human embryonic stem cells CRISPR/Cas9 genomic editing Mass spectrometry proteomic analysis hypertrophic cardiomyopathy disease model physical exercise cardiac cellular regeneration microRNA (miR) Akt signaling cardiomyocyte proliferation cardiac hypertrophy cardioprotection myocarditis inflammation leukocytes cardiomyocytes multi-electrode-array micro-electrode-array MEA drug/toxicity screening field potential arrhythmia electrocardiography cardiac regeneration stem cells iPSC PSC ESC cardiovascular disease regeneration cardiac progenitor cells induced pluripotent stem cells transdifferentiation direct reprogramming genetic engineering cardiac tissue engineering biomaterials 18F-FDG PET cardiac induced cells cardiac function non-invasive imaging human pluripotent stem cell ventricular maturation bone marrow stem cells angiogenesis myocardial infarction human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) iPS cells big conductance calcium activated potassium channel (BK) Maxi-K slo1 KCa1.1 iberiotoxin long QT syndrome mesenchymal stromal cells (MSC) mRNA miRNA cardiac reprogramming cardiac differentiation cardiovascular diseases adult stem cells myocardial infraction 3D printing 3D model bioprinting cardiovascular medicine heart myocardium heart valves vascular graft endothelialization tissue engineering decorin fibronectin electrospinning endothelial progenitor cells bioreactor biostable polyurethane MicroRNA Mir-133 coronary heart disease biomarker meta-analysis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557701803321 |
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David Robert
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
| Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression |
| Autore | Stefanachi Angela |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
EGR-1
flavonoid (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile MDA-MB-231 MMP9 TNFα pancreatic ductal adenocarcinoma cyclodextrin inclusion complex phase solubility studies preformulation studies biphenylnicotinamide derivatives dual inhibitor EGFR VEGFR2 ligand-based pharmacophore molecular docking molecular dynamics leukemias doxorubicin inflammation drug delivery tumor targeting elastin-like polypeptide cell penetrating peptide matrix metalloproteinase doxorubicin resistance photosensitizer delivery system PAMAM dendrimer photodynamic therapy cytotoxicity phototoxicity colorectal adenocarcinoma dicarboximides chemical synthesis apoptosis kinases anticancer gene profiling SAR biomarkers colorectal cancer early detection examination liquid biopsy personalized medicine tumor treatment exosomes ctDNA CTC cytotoxic activity pyrazole derivatives MTT assay ADMET analysis single-crystal diffraction FTIR spectroscopy NMR spectroscopy thermogravimetric analysis acute myelogenous leukemia platelets microparticles γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor neuroblastoma molecular iodine cyclophosphamide xenografts metronomic therapy tamoxifen CYP2D6 MCF-7 Ishikawa cells SERM TNBC uterotrophic α-mangostin poly(amidoamine) dendrimer targeted drug delivery biotin targeting glioblastoma multiforme squamous cell carcinoma antiparasitic therapy diclofenac indomethacin oleanolic acid derivative conjugates NF-κB Nrf2 MAPKs PSN-1 cells reactive oxygen species glioblastoma brain tumor extracellular vesicles pancreatic cancer paclitaxel clathrin endocytosis sulforaphane nicotine metalloproteinase-9 gastric cancer cell invasion Arylquin 1 colon cancer tumor progression azelastine oxidative stress autophagy mitotic catastrophe chronic myeloid leukemia imatinib tyrosine kinase ketoconazole P-glycoprotein drug efflux transporter non-small-cell lung cancer cisplatin resistance aldehyde dehydrogenase isothiocyanates disulfiram epithelial to mesenchymal transition aminopeptidase N acetamidophenones Schiff bases semicarbazones thiosemicarbazones inhibition of proliferation |
| ISBN | 3-0365-5927-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639990003321 |
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Stefanachi Angela
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Stroke, Dementia and Atrial Fibrillation
| Stroke, Dementia and Atrial Fibrillation |
| Autore | Russo Vincenzo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (212 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
memory loss
antioxidant neuroprotective acetylcholinesterase inhibitor molecular docking atrial fibrillation venous thrombosis anticoagulation perception chronic obstructive pulmonary disease atrial fibrillation cardiovascular risk outcome prognosis novel oral anticoagulants prosthetic valve replacement subclinical atrial fibrillation stroke ischemic cerebral events catheter ablation screening cognitive impairment atrial fibrillation ablation iatrogenic interatrial septum defect paradoxical embolism anticoagulant interruption cardioversion oral anticoagulation therapy left atrial appendage thrombosis transesophageal echocardiography IL1B IL1RN polymorphism inflammation cognitive decline rhythm control microbleeds cerebral ischemia diabetes mellitus metformin thiazolidinediones GLP-1 receptor agonists SGLT-2 inhibitors atrial high rate episodes NOACs non vitamin K oral anticoagulants oral anticoagulation intracerebral hemorrhage cerebral small vessel disease brain MRI circulating biomarkers direct oral anticoagulants (DOACs) atrial fibrillation (AF) electrical cardioversion (EC) surgical cryoablation left atrial function minimally invasive mitral valve repair echocardiography aneurysmal subarachnoid hemorrhage interdisciplinary setting metabolic syndrome obesity dementia |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557585603321 |
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Russo Vincenzo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Structural and Functional Analysis of Extracts in Plants
| Structural and Functional Analysis of Extracts in Plants |
| Autore | Lamponi Stefania |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (465 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
hierarchical cluster analysis
principal component analysis ultrasound-assisted extraction triterpenic acid Ziziphus jujuba water-pepper FRAP DPPH polarity-based solvent extraction α-amylase inhibition circular economy green biorefinery polyunsaturated fatty acids phytochemicals amino acids food and feed UHPLC-ESI-ORBITRAP-MS/MS Bergenia emeiensis polysaccharides optimization RSM acrylamide-induced damage Sorbus commixta fruit anti-melanoma activity caspase-3 polyphenolic compounds depression antioxidant cytokines anti-inflammatory cytotoxicity medicinal mushroom Psilocybe natalensis coak oak chlorophyll terpenes lupeol cuticular permeance Suaeda vermiculata halophyte aqueous-ethanolic extract liver toxicity hepatoprotective liver disorders mass spectrometry LC-MS HepG-2 HepG-2/ADR zebrafish toxicity embryotoxicity medicinal plant animal model Crocus sativus in vivo carrageenan analgesic antidepressant anticoagulant adipogenesis AMPK anti-obesity triglycerides UCP1 Anacardiaceae design of experiments (DOEs) flavonoids green extraction HPLC-DAD LC-MS/MS tannins ultrasound assisted-extraction (UAE) compact mass spectrometry cleansing properties detergent plants phytochemical tissue culture Arbutus pavarii antibacterial activity MRSA time-kill curves ultrahigh-performance liquid chromatography mass spectrometry (UHPLC- ESI-MS/MS) Trigonella stellata caffeic acid osteoporosis osteoblast osteoclast BMP Euphorbia cuneata Euphorbiaceae lipopolysaccharide oxidative stress NF-κB lung injury pachycereus weberi escontria chiotilla antioxidant activity phenolic compounds betalains food composition food analysis Scrophularia buergeriana S. koraiensis S. takesimensis harpagoside osteoclast differentiation RANKL Araucaria angustifolia bioactive compounds cysteine protease inhibitor functional food insecticide plant extracts termites tumor cells pine nuts urban pest polyphenols fruit development natural food colorant Sambucus canadensis Japanese knotweed Reynoutria Polygonum Polygonaceae anthraquinones emodin physcion HPTLC HPTLC-MS densitometry carrot juices carotenoids high-speed juicer low-speed juicer food processing extraction glucosinolates kale (Brassica oleracea var. acephala) phenolics candelilla plant antioxidant properties antimicrobial activity candelilla cultivation candelilla wax polysterols saponins therapeutic properties sage stirring and heating extraction mechanochemical extraction antiproliferative activity mutagenicity anticoagulant activity Rosmarinus officinalis hydroalcoholic extract Sam-Myo-Whan traditional medicine gouty arthritis inflammation monosodium urate Underutilized Mexican plants Cactus fruits Antioxidant activities Antiproliferative properties |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557474303321 |
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Lamponi Stefania
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Structure, Activity, and Function of Protein Methyltransferases
| Structure, Activity, and Function of Protein Methyltransferases |
| Autore | Jeltsch Albert |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (292 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
protein lysine methylation
H3K9 methylation PKMT enzyme specificity enzyme regulation heterochromatin protein post-translational modification NSD3 WHSC1L1 structure and function protein arginine methylation PRMT7 epigenetics cancer immunity pluripotency SETDB1 methyltransferase schizophrenia Huntington's disease Rett syndrome Prader-Willi syndrome congenital heart diseases inflammatory bowel disease MLL2 structure H3K4me3 chromatin regulation disease dystonia NSD1 H3K36 SOTOS NUP98-NSD1 AML PRMT6 post-translational modification H3R2me2a SETD3 posttranslational modifications protein histidine methylation actin polymerization cytoskeleton enteroviruses oncogenesis PRMT5 cardiovascular disease neurodegenerative diseases diabetes inflammation G9a GLP EHMT2 EHMT1 post translational modification lysine methylation N-terminal methylation translation eEF1A METTL13 neuron synapse dendritic spine actin cytoskeleton GTPase PRMT1 arginine methylation H4R3 methylation transcriptional regulation cell signaling DNA damage repair PRMT2 SH3 SETMAR Metnase H3K36me2 Hsmar1 non-homologous end joining repair NHEJ transposase transposable elements histone SET7/9 SETD7 lysine-specific methyltransferase (PKMT) cell proliferation stress response post-translational protein modification |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566479603321 |
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Jeltsch Albert
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Structure, Isotypes, Targets, and Post-Translational Modifications of Immunoglobulins and Their Role in Infection, Inflammation and Autoimmunity
| Structure, Isotypes, Targets, and Post-Translational Modifications of Immunoglobulins and Their Role in Infection, Inflammation and Autoimmunity |
| Autore | Hermouet Sylvie |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (171 p.) |
| Soggetto topico |
Medicine
Immunology |
| Soggetto non controllato |
immunoglobulins
glycosylation targets inflammation infection autoimmunity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557213303321 |
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Hermouet Sylvie
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Synthesis of Marine Natural Products and Molecules Inspired by Marine Substances II
| Synthesis of Marine Natural Products and Molecules Inspired by Marine Substances II |
| Autore | Manzo Emiliano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (111 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
In-silico drug design
virtual screening Avicennia alba gag polyprotein homology modeling ADMET molecular dynamics simulation divergent total synthesis marine natural products tetracyclic meroterpenoids aureol (−)-majusculoic acid anti-inflammation LPS CCK-8 animal studies marine alkaloids biological activity cancer cardiovascular diseases inflammation chemical synthesis ilamycins rufomycins cyclomarins tuberculosis malaria cyclopeptides biosynthesis total synthesis natural products |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557724503321 |
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Manzo Emiliano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Systemic Autoinflammatory Diseases-Clinical Rheumatic Challenges
| Systemic Autoinflammatory Diseases-Clinical Rheumatic Challenges |
| Autore | Feist Eugen |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (266 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
gout
febuxostat colchicine hepatotoxicity prophylaxis myositis inflammatory idiopathic myopathy dysphagia aspiration pneumonia immunoglobulin G4-related orbital disease (IgG4-ROD) orbital lymphoma (OL) computed tomography (CT) Hounsfield unit imaging autoinflammation arthritis CAPS FCAS MWS CINCA NOMID hearing loss urticarial-like rash autoinflammatory disease anti-IL-1 treatment rheumatoid arthritis synovitis neoplasms edema inflammation new genetic variant monogenic autoinflammatory syndrome diagnostic delay anakinra damage index genetic inheritance personalized therapy Interleukin-1 autoinflammatory diseases FMF coronavirus SARS-CoV-2 antibody response adult-onset Still's disease autoinflammatory disorder systemic-onset juvenile idiopathic arthritis haemophagocytic lymphohistiocytosis macrophage activation syndrome IFN-γ JAK inhibitor proliferation DNA damage repair γH2AX PBMCs T lymphocytes proteasome autoimmune proteasome-associated autoinflammatory syndrome therapy IL-1 inhibitors NGS SURF spondyloarthritis human leukocyte antigen undifferentiated enthesitis and/or arthritis ASAS classification criteria clinical management canakinumab cytokines |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557349503321 |
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Feist Eugen
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeting Monocytes/Macrophages to Treat Atherosclerotic Inflammation
| Targeting Monocytes/Macrophages to Treat Atherosclerotic Inflammation |
| Autore | Corti Alessandro |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (127 p.) |
| Soggetto topico |
Science: general issues
Pharmacology |
| Soggetto non controllato |
monocytes/macrophages
inflammation foam cell formation smooth muscle cells atherosclerosis progression |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557600203321 |
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Corti Alessandro
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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