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Targeting Wnt Signaling in Cancer: Opportunities Abound If We Can Avoid the Sword of Damocles
| Targeting Wnt Signaling in Cancer: Opportunities Abound If We Can Avoid the Sword of Damocles |
| Autore | Kahn Michael |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (298 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
Wnt signaling
synovial sarcoma TNIK NCB-0846 MYC hepatitis B virus HBV cancer liver cancer β-catenin TCF/LEF pancreatic cancer pancreatic stellate cells CBP p300 pancreatitis fibrosis just-right signaling APC colorectal cancer RNA-binding proteins Musashi drug discovery Notch signaling cancer therapy fungi secondary metabolite derivative microenvironment Wnt AML drug target signaling colorectal porcupine R-spondin serrated immunotherapy wnt vitamin D colon cancer L1 Wnt target genes cell adhesion NF-κB invasion and metastasis cancer stem cells EMT Lgr5 Wnt/beta-catenin signaling angiogenesis anti-angiogenic therapy gastrointestinal cancers therapeutic targeting of Wnt signaling β-catenin paradox molecular targeting urothelial cancer immune checkpoint inhibitor immunotherapy resistance IBD colitis β-catenin mutations tumor metabolism tumor immunology molecular therapeutics precision medicine astrocytic brain tumors DKKs GSK3β |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Targeting Wnt Signaling in Cancer |
| Record Nr. | UNINA-9910566469503321 |
Kahn Michael
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Interplay of Microbiome and Immune Response in Health and Diseases
| The Interplay of Microbiome and Immune Response in Health and Diseases |
| Autore | Barceló-Coblijn Gwendolyn |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (206 p.) |
| Soggetto non controllato |
gastrointestinal diseases
sterile inflammation Staphylococcus spp etiopathogenesis colitis Escherichia coli bacteriophages atopic dermatitis intravenous immunoglobulin G adaptive immunity 16S rRNA gene vaginal microbiota modularity innate immunity gut-liver axis disease activity immune system cytokines commensals Staphylococcus aureus dysbiosis fecal transplantation TLR mimicry etanercept dextran sulfate sodium CAR T-cell 3-dihydroxy-4-methoxyBenzaldehyde chemo free treatment Staphylococcus epidermis rheumatoid arthritis microbiome co-occurrence network immune epigenetics 2 autoimmunity superoxide dismutase precision medicine metabolism adoptive cell transfer (ACT) gut barrier antibiotics checkpoint inhibitors probiotics microbiota Candida albicans Enterococcus faecalis chronic liver diseases TCR anaerobic bacteria HSV2 bacteriocins methotrexate microbial interactions T cells virus mice lymphoid malignancies HPV macrophages anti-TNF-? inflammation chondroitin sulfate disaccharide immunotherapy genomics immuno-oncology diet aerobic bacteria immunological niche melanin health chemokines gut microbiota cutaneous immunity HIV TIL cancer global network |
| ISBN | 3-03921-647-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367747303321 |
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Barceló-Coblijn Gwendolyn
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Molecular and Cellular Basis for Parkinson's Disease
| The Molecular and Cellular Basis for Parkinson's Disease |
| Autore | Müller Thomas |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (230 p.) |
| Soggetto non controllato |
microRNAs
disease-modifying effects SH-SY5Y inpatient treatment sphingolipids neurodegeneration magnetic resonance spectroscopy MO3.13 schizophrenia epigenetics long-chain acylcarnitine molecular mimicry curli multimodal complex treatment chlorogenic acid glycerophospholipids caffeic acid lipoproteins myenteric plexus neurometabolites HOG immature oligodendrocyte autophagy oligodendrocyte hypochlorite alpha-synuclein microbiome glucocerebrosidase Lewy Body Dementia brain iron mesenchymal stem cells fatty acid ?-oxidation GABA enteric glial cell gut-brain axis microbiota REM sleep behavior disorders redox cycling magnetic resonance imaging differentiation ?-synuclein-mediated pathology Parkinson disease Gaucher’s disease metallothionein [123I]FP-CIT-SPECT dopaminergic neuron mature oligodendrocyte glycerolipids spectroscopy neuroinflammation exosomes immunotherapy DNA methylation sterol lipids nigral cells cell line cysteinyl-dopamine myelin parkinsonisms multiple sclerosis rotenone brain fatty acyls Krabbe’s disease neuroprotection DAT motor dysfunction secretome multiprofessional therapy Parkinson’s disease oxidative stress alpha-Synuclein |
| ISBN | 3-03921-549-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367753003321 |
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Müller Thomas
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Second Life of Natural Killer (NK) Cells
| The Second Life of Natural Killer (NK) Cells |
| Autore | Joseph C. Sun |
| Pubbl/distr/stampa | Frontiers Media SA, 2018 |
| Descrizione fisica | 1 electronic resource (118 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
natural killer cells
ILC NK cells immune therapy viral infection NK cell education immunotherapy MHC-I cancer immune regulation adaptive immunity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Second Life of Natural Killer |
| Record Nr. | UNINA-9910345960903321 |
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Joseph C. Sun
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| Frontiers Media SA, 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Shaping of Cancer by the Tumour Microenvironment and Its Relevance for Cancer Therapy
| The Shaping of Cancer by the Tumour Microenvironment and Its Relevance for Cancer Therapy |
| Autore | Madureira Patrícia Alexandra Saraiva |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (307 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
hypoxia
macrophages colon cancer tumor microenvironment immune cell infiltration prognosis feline mammary carcinoma PD-1 PD-L1 CTLA-4 TNF-α biomarkers immunotherapy cancer histone modification inhibitor KDM5B molecular docking repurposing cancer acidity hyperosmolarity cross-presentation tumour microenvironment syngeneic model prostate cancer radiotherapy preclinical modelling myeloid-derived suppressor cells biomarker stroma cancer-associated fibroblast (CAF) extracellular matrix (ECM) cytokine/chemokine growth factors pro- and anti-tumor immune cells immunomodulatory roles radiotherapy dose fractionation radioresistance radiosensitivity breast cancer S100A10 (p11) tumor growth tumor progression metastasis carcinoma mammary gland triple negative pre-metastatic niche pro-inflammatory cytokines clinical trials evolutionary therapy darwinian evolution cancer cells subpopulations diclofenac koningic acid spheroid 3D co-culture microenvironment resistance myeloid cells cancer development molecular subtypes of pancreatic cancer chemotherapy response pancreatic stellate cells regulatory T cells tumor-associated macrophages myeloid derived suppressor cells glioblastoma (GB) Hypoxia Inducible Factor (HIF) glioma stem cells (GSC) oxidative stress reactive oxygen species plasmin plasminogen S100A10 uPA uPAR PAI-1 PAI-2 cancer stem cells cancer recurrence therapeutic resistance signaling pathways targeted therapy head and neck cancer lung cancer bladder cancer |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557354203321 |
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Madureira Patrícia Alexandra Saraiva
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Towards New Promising Discoveries for Lung Cancer Patients: A Selection of Papers from the First Joint Meeting on Lung Cancer of the FHU OncoAge (Nice, France) and the MD Anderson Cancer Center (Houston, TX, USA)
| Towards New Promising Discoveries for Lung Cancer Patients: A Selection of Papers from the First Joint Meeting on Lung Cancer of the FHU OncoAge (Nice, France) and the MD Anderson Cancer Center (Houston, TX, USA) |
| Autore | Hofman Paul |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (230 p.) |
| Soggetto non controllato |
microRNAs
multiplexed screening education non-smoker image analysis artificial intelligence research lung cancer spatial analysis optimization fluorescence geriatric assessment geriatric interventions TNBC liquid biopsy non-small cell lung cancer integrated approaches well-being hormone-like action EGFR mutations reversal of EMT tumor plasticity immune profiling macrophage multiplexed methodologies targeted treatment techniques immune-oncology bioinformatics MALAT1 long non-coding RNAs CD8 T Cells personal medicine EGFR TKIs lncRNA hormones elderly interleukin-1? and immunometabolism chromogenic xenograft metastasis PD-1/PD-L1 checkpoint blockade immunotherapy molecular cancer tissues digital NSCLC immune blockade lung adenocarcinoma circulating tumor cells brightfield non-coding RNAs older adults cancer tumor microenvironment aging rational therapy |
| ISBN | 3-03921-452-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Towards New Promising Discoveries for Lung Cancer Patients |
| Record Nr. | UNINA-9910367760103321 |
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Hofman Paul
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Toxins and Cancer Therapy
| Toxins and Cancer Therapy |
| Autore | Snook Adam E |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (104 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
immunotoxin
ribotoxin α-sarcin RNase T1 furin intracellular trafficking colorectal cancer botulinum toxin botulinum neurotoxin cancer cancer cells neuropathic pain post-surgical pain parotid gland submaxillary gland gustatory hyperhidrosis sialocele parotid fistula immunotherapy vaccine immune checkpoint inhibitors adoptive cell therapy cytokine therapy Coley's Toxins glioblastoma drug discovery cytotoxic necrotizing factor type 1 protein purification recombinant protein production shiga toxins Gb3/CD77 apoptosis ER stress autophagy Burkitt lymphoma |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557123603321 |
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Snook Adam E
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Treatments for Squamous Cell Cancer
| Treatments for Squamous Cell Cancer |
| Autore | Darido Charbel |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (168 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
oral cancer
tobacco alcohol human papilloma virus targeted sequencing DNA copy number TP53 CDKN2A EGFR PIK3CA anal cancer radiation therapy chemoradiation de-escalation of therapy pain cathepsin S protease-activated receptor-2 PAR2 cancer pain oral squamous cell carcinoma differentiation terminal differentiation oral epithelium epithelial integrity epithelial transformation genetic alterations therapy response biomarkers cutaneous squamous cell carcinoma immunotherapy anti-PD1 biomarkers predictive medicine personalized medicine cancer immune system HNSCC farnesyl transferase tipifarnib combination regimen oropharynx neoplasm squamous cell carcinoma human papillomavirus therapeutic management treatment selection CSCC treatment advances biology immunocompromised immune checkpoint inhibition |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595074003321 |
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Darido Charbel
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumor Microenvironment and Resistance to Current Therapies
| Tumor Microenvironment and Resistance to Current Therapies |
| Autore | Lasfar Ahmed |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (148 p.) |
| Soggetto topico |
Science: general issues
Pharmacology |
| Soggetto non controllato |
cancer resistance
tumor—targeting tumor microenvironment immunotherapy therapy resistance cancer cell signaling targeted therapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557262603321 |
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Lasfar Ahmed
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Urological Cancer 2021
| Urological Cancer 2021 |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (328 pages) |
| Soggetto topico |
Research
Chemistry |
| Soggetto non controllato |
bladder cancer
radiotherapy radiosensitisation molecular subtypes preclinical studies bladder cancer cell lines latent cancer prostate cancer autopsy prognostic index prediction model mortality screening trial renal cell carcinoma PD-1 PD-L1 biomarkers immune checkpoint inhibitors prostatic neoplasms positron-emission tomography decision making tumor thrombus metastasectomy postoperative complications oncological outcomes radical cystectomy AHNAK2 prognosis dog comparative oncology inflammation prostatic atrophy preneoplastic lesion biomarker urine machine learning TRIPOD liquid biopsy glutaminase immunohistochemistry in situ methods prostate PSMA-RLT 177Lu-PSMA PSA mCRPC urinary bladder neoplasms Bacillus Calmette-Guérin (BCG) immunotherapy divergent differentiation variant morphology survival stereotactic body radiotherapy frail patients cancer metastasis genomic analysis microenvironment tumor ecology game theory fluorescence confocal microscopy prostate biopsy ablation margins focal therapy sphingosine 1-phosphate receptor 1 bladder carcinoma cell migration epithelial-mesenchymal transition FTY-720 OIP5 papillary renal cell carcinoma PLK1 tumorigenesis therapy image-guided magnetic resonance imaging ultrasonography biopsy abiraterone enzalutamide docetaxel novel hormonal therapies comparative effectiveness real-world treatment pattern metastatic prostate cancer epiplakin diagnosis advanced urothelial carcinoma immune checkpoint inhibitor prognostic tumour mutational board genomic signatures ctDNA inflammatory indices urothelial carcinoma frailty prognostic factor psoas muscle Hounsfield units |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576872803321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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